Modeling device for rat CUMS depression model

By designing a device that flexibly adjusts the living space and stimulation of laboratory mice, the problems of time-consuming and labor-intensive operation and inconsistent experimental conditions of existing devices are solved, thereby improving operational efficiency and experimental success rate.

CN223652939UActive Publication Date: 2025-12-12河南医药大学第二附属医院(河南省精神病医院)
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Patent Information

Application Number
CN202423278042.X
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-12-30
Publication Date
2025-12-12
Estimated Expiration
2034-12-30

AI Technical Summary

Technical Problem

Existing rat CUMS depression model establishment devices are time-consuming, labor-intensive, inefficient, and prone to inconsistent experimental conditions, leading to experimental failure.

Method used

A device was designed that includes a stepped upright plate, a string of rat cages, a guide rod, a limiting plate, a lead screw, and a noise generator. It can flexibly adjust the living space, accessibility to drinking water, and noise stimulation of laboratory rats. The space and drinking water can be flexibly adjusted through positioning pins and handwheels. The noise generator is electrically connected to the controller.

Benefits of technology

This allows for flexible adjustment of the living space of laboratory mice and multi-angle stimulation, improving operational efficiency, ensuring consistency of experimental conditions, and reducing the possibility of experimental failure.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model provides a rat CUMS depression model making device which comprises two vertical plates, a baffle and a plurality of mouse cage strings are arranged on the rear side between the two vertical plates, and each mouse cage string comprises a plurality of mouse cage bodies. Each mouse cage body comprises a bottom plate located at the bottom, two side plates are arranged on the bottom plate, a cover plate is hinged to the tops of the two side plates, protective nets are arranged on the front side and the rear side between the two side plates respectively, the mouse cage bodies are connected through connecting rods, and the connecting rods on the side plates located on the outer sides of the mouse cage bodies at the two ends are rotationally connected with vertical plates; each mouse cage string is provided with a guide rod, the guide rods penetrate through the mouse cage bodies, two limiting plates which are arranged on the guide rods in a sliding mode are arranged in each mouse cage body, the mouse cage strings are further provided with lead screws which penetrate through the mouse cage bodies and are rotationally connected with the mouse cage bodies, and the lead screws are in threaded connection with the limiting plates in the mouse cage bodies. The structural design of the rat CUMS depression model modeling device provided by the utility model can stimulate an experimental rat from multiple angles to complete a CUMS depression model.
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Description

TECHNICAL FIELD

[0001] The utility model belongs to the medical experimental technical field, concretely relates to a rat CUMS depression model moulding device. BACKGROUND

[0002] The chronic unpredictable stress (CUMS) depression model is an effective animal depression model, and the CUMS stress process includes the following steps: depriving experimental rats of water, depriving experimental rats of food, reversing day and night, noise stimulation, overnight wetting, electric shock stimulation, limited space restraint, low-frequency flash lamp stimulation, etc., and the stimulation intensity, batch and sequence of all experimental rats in each batch test should be the same and end until the end.

[0003] Therefore, a new moulding device is needed to solve the above problems. UTILITY MODEL CONTENTS

[0004] The utility model aims at the shortage of prior art, provides a rat CUMS depression model moulding device, and the specific scheme is as follows:

[0005] A rat CUMS depression model moulding device, including two ladder-shaped vertical plates, the rear side between the two vertical plates is provided with a baffle, and a plurality of rat cage strings are further arranged between the two vertical plates, each rat cage string includes a plurality of rat cage bodies;The rat cage body includes a bottom plate at the bottom, two side plates are arranged on the bottom plate, a cover plate is hingedly arranged on the top of the two side plates, a protective net is arranged between the two side plates, a plurality of rat cage bodies are connected through connecting rods, and the connecting rods on the side plates of the rat cage bodies at both ends are rotatably connected with the vertical plates;A guide rod is arranged on each rat cage string, the guide rod penetrates through a plurality of rat cage bodies, two limiting plates are arranged in each rat cage body and are slidably arranged on the guide rod, a lead screw is further arranged on the rat cage string and rotatably connected with the plurality of rat cage bodies, the lead screw is screwed with the limiting plates in each rat cage body, and the thread rotation directions of the two limiting plates in each rat cage body are opposite.

[0006] Based on the above, a plurality of positioning holes are arranged on the side plate of one of the rat cage bodies, and a positioning pin corresponding to the positioning holes is arranged on one of the vertical plates and penetrates and slides.

[0007] Based on the above, a water bottle is arranged on the cover plate, the water bottle includes a bottle body penetrating through the cover plate, a threaded cylinder is arranged on the bottle body and screwed with the cover plate, and a gravity ball is arranged at the water outlet position of the water bottle.

[0008] Based on the above, a noise generator is arranged on one of the vertical plates and electrically connected with the controller arranged on the vertical plate.

[0009] Based on the above, one end of the lead screw is provided with a hand wheel.

[0010] The utility model discloses relative prior art has substantial feature and progress, specifically speaking, the utility model has the following advantages:

[0011] The rat CUMS depression model molding device has the structural design that can flexibly adjust the level of the survival space of experimental rats, the size of the survival space and the convenience degree of the survival space drinking water, and then completes the CUMS depression model from multiple angles. BRIEF DESCRIPTION OF DRAWINGS

[0012] Figure 1 It is the overall structure schematic diagram of the utility model.

[0013] Figure 2 It is Figure 1 The structure schematic diagram of A place in middle.

[0014] Figure 3 It is the partial structure side view of the utility model.

[0015] Figure 4 It is the structure schematic diagram of drinking water bottle in the utility model.

[0016] Figure 5 It is the side view of the utility model.

[0017] In the drawing: 1. vertical board;2. baffle;3. mouse cage string;4. mouse cage body;5. bottom plate;6. cover plate;7. protective net;8. drinking water bottle;8-1. bottle body;8-2. water outlet nozzle;8-3. gravity ball;8-4. threaded cylinder;9. limiting plate;10. guide rod;11. lead screw;12. hand wheel;13. connecting rod;14. positioning hole;15. positioning pin;16. noise generator;17. controller. DETAILED DESCRIPTION

[0018] The technical scheme of the utility model is further described in detail below through specific embodiments. EMBODIMENT

[0019] As Figures 1-5As shown, the utility model provides a rat CUMS depression model moulding device, including two piece ladder shape's vertical board 1, two piece the rear side between the vertical board 1 is equipped with baffle 2, still be equipped with multiple mouse cage string 3 between two vertical boards 1, every mouse cage string 3 includes multiple mouse cage body 4;The mouse cage body 4 includes the bottom plate 5 at bottom, is equipped with two side plates on bottom plate 5, the top of two side plates is hinged and is equipped with cover plate 6, is equipped with protective net 7 between two side plates front and back side respectively, multiple mouse cage body 4 is connected through connecting rod 13, and the connecting rod 13 on the outside side plate of mouse cage body 4 at both ends is rotatably connected with vertical board 1;Every mouse cage string 3 is equipped with guide rod 10, and guide rod 10 penetrates multiple mouse cage body 4, and two limit plates 9 that slide in guide rod 10 are equipped in every mouse cage body 4, and still be equipped with screw rod 11 that penetrates multiple mouse cage body 4 and is rotatably connected with it on mouse cage string 3, the limit plate 9 in every mouse cage body 4 inside is screwed with screw rod 11, and the thread rotation direction of the two limit plates 9 in every mouse cage body 4 inside corresponding screw rod 11 is opposite.

[0020] For the convenience of adjusting the inclination angle of mouse cage string 3, the side plate of one of the mouse cage bodies 4 is provided with a plurality of positioning holes 14, and one of the vertical boards 1 is provided with a positioning pin 15 penetrating and slidingly arranged in the positioning holes 14.

[0021] The cover plate 6 is provided with a drinking bottle 8, and the drinking bottle 8 includes a bottle body 8-1 penetrating the cover plate 6, the bottle body 8-1 is provided with a threaded cylinder 8-4 screwed with the cover plate 6, and a water outlet 8-2 of the drinking bottle 8 is provided with a gravity ball 8-3.

[0022] For the convenience of applying noise stimulation to the rats, one of the vertical boards 1 is provided with a noise generator 16 electrically connected with a controller 17 arranged on the vertical board 1.

[0023] For the convenience of rotating the screw rod 11, one end of the screw rod 11 is provided with a hand wheel 12.

[0024] The rat CUMS depression model moulding device can flexibly adjust the levelness of the survival space of the experimental rats, the size of the survival space and the convenience of drinking water in the survival space, and is also convenient for applying noise interference to the experimental rats, so that the experimental rats are stimulated from multiple angles to complete the CUMS depression model.

[0025] It should be noted finally that: the above examples are only used to illustrate the technical solutions of the utility model and not to limit them; although the utility model has been described in detail with reference to the preferred embodiments, those skilled in the art should understand that: the specific embodiments of the utility model can still be modified or some technical features can be replaced by equivalents; without departing from the spirit of the technical solutions of the utility model, they should be covered in the technical solution range of the utility model claimed.

Claims

1. A rat CUMS depression model device, characterized in that: The utility model provides a kind of noise reduction device, including two stepped vertical plates (1), back side is equipped with baffle (2) between two described vertical plate (1), still be equipped with multiple squirrel cage string (3) between two vertical plate (1), each squirrel cage string (3) includes multiple squirrel cage body (4);The squirrel cage body (4) includes bottom plate (5) at bottom, bottom plate (5) is equipped with two side plates, the top of two side plates is hingedly equipped with cover plate (6), front and back sides between two side plates are equipped with protective net (7), multiple squirrel cage body (4) are connected by connecting rod (13), the connecting rod (13) on the side plate of the outer side of squirrel cage body (4) located at both ends is rotatably connected with vertical plate (1);Every squirrel cage string (3) is equipped with guide rod (10), guide rod (10) penetrates multiple described squirrel cage body (4), every squirrel cage body (4) is equipped with two limit plates (9) slidingly arranged on guide rod (10), squirrel cage string (3) is also equipped with screw rod (11) penetrating multiple squirrel cage body (4) and being rotatably connected with it, the screw rod (11) is screwed with the limit plate (9) in every squirrel cage body (4) and the thread rotation direction of the two limit plates (9) in every squirrel cage body (4) corresponding to screw rod (11) is opposite.

2. The rat CUMS depression model modeling device according to claim 1, characterized in that: The side plate of one of the described squirrel cage body (4) is equipped with multiple positioning holes (14), and one of the vertical plate (1) is equipped with a positioning pin (15) penetrating and slidingly arranged corresponding to the positioning hole (14). 3.The rat CUMS depression model modeling device according to claim 1, characterized in that: The cover plate (6) is equipped with a drinking bottle (8), the drinking bottle (8) includes a bottle body (8-1) penetrating the cover plate (6), the bottle body (8-1) is equipped with a threaded cylinder (8-4) screwed with the cover plate (6), and a water outlet (8-2) of the drinking bottle (8) is provided with a gravity ball (8-3).

4. The rat CUMS depression model modeling device according to claim 3, characterized in that: One of the vertical plate (1) is equipped with a noise generator (16), and the noise generator (16) is electrically connected with a controller (17) arranged on the vertical plate (1).

5. The rat CUMS depression model modeling device according to claim 1, characterized in that: One end of the screw rod (11) is provided with a hand wheel (12).