Experimental animal trachea instillation device

By designing an experimental animal tracheal drip device, the problem of secretions entering the trachea during nasal drip was solved, achieving safe and efficient drug dripping and nasal cavity cleaning, and ensuring the reliability of experimental results.

CN223653985UActive Publication Date: 2025-12-12SHENZHEN FUTIAN DISTRICT SECOND PEOPLES HOSPITAL
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Patent Information

Application Number
CN202422233065.2
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-09-12
Publication Date
2025-12-12
Estimated Expiration
2034-09-12

AI Technical Summary

Technical Problem

When administering medication via nasal instillation into the trachea of ​​experimental animals, secretions can easily enter the trachea along with the medication, posing a safety hazard and affecting experimental results.

Method used

A tracheal dripping device for experimental animals was designed, including a fixing part, an insertion part, and an adjustment part. By adjusting the angle and position of the animal, the insertion part is used to drip the drug directly into the trachea, and the insertion part is used to clean the nasal cavity to prevent secretions from entering the trachea.

Benefits of technology

It effectively prevents nasal secretions from entering the trachea, improving the safety and accuracy of the experiment and ensuring the reliability of the experimental results.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model provides an experimental animal trachea instillation device, which relates to the technical field of animal experiments, and comprises a fixing part, the fixing part is used for fixing four limbs of an animal, and the angle of the fixing part is adjusted, so that the angle of the animal can be adjusted; an animal is fixed on the fixing part, when the nasal cavity needs to be flushed, the driving part moves downwards by adjusting the end, located on the head of the animal, of the fixing plate, the head of the animal is lower than the legs at the moment, the fixing tube and the instillation hose are inserted into the nasal cavity, normal saline is injected into the nasal cavity through the instillation hose, and the nasal cavity is flushed; wastewater and secreta generated after flushing can be discharged out of the nasal cavity through the cavity, the nasal cavity can be conveniently cleaned, after cleaning is completed, medicine is instilled into the trachea through the instillation hose, an instillation experiment can be conveniently carried out, secreta in the nasal cavity can be effectively prevented from entering the trachea, and the experiment safety is improved.
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Description

TECHNICAL FIELD

[0001] The utility model relates to animal experiment technical field, concretely is a kind of experimental animal tracheal instillation device. BACKGROUND

[0002] Experimental animal tracheal instillation is a common drug delivery method, especially widely used in the study of lung disease model, usually choose mouse as experimental animal, gender is unlimited, age is generally 6-8 weeks, variety such as balb / c, C57BL / 6J etc.

[0003] Because animal nasal cavity is prone to secretions and other impurities, when instillation experiment is carried out through nose, secretions are prone to enter the trachea of animal along with liquid medicine, which has certain safety hazard to animal and affects the experimental results. UTILITY MODEL CONTENT

[0004] The utility model aims at providing a kind of experimental animal tracheal instillation device, to solve the problem of existing technology in the instillation experiment through nose, secretions are prone to enter the trachea of animal along with liquid medicine, which has certain safety hazard to animal and affects the experimental results.

[0005] To achieve the above-mentioned purpose, the utility model adopts the following technical scheme: the experimental animal tracheal instillation device includes fixed part;For the limbs of animal are fixed, and the angle of fixed part is adjusted, and then the angle of animal can be adjusted;Insertion part: set on fixed part, insertion part can be inserted into the nasal cavity of animal, so that medicine is instilled into the trachea of animal, and normal saline can be injected into the nasal cavity through insertion part;Adjusting part: set below fixed part, for adjusting the angle of fixed part, so as to adjust the angle of animal according to use condition, clean the nasal cavity, when instilling medicine, adjust fixed part to the position where the position of animal head is higher than the position of leg, when cleaning the nasal cavity, adjust fixed part to the position where the position of leg is higher than the position of head.

[0006] The further technical scheme of the utility model is that the fixed part includes fixed plate, four belts are arranged on the fixed part, and the limbs of animal are fixed by the belts

[0007] The further technical scheme of the utility model is that the insertion part includes fixed disc fixedly connected to the fixed plate, the fixed disc is located at one side of the head of animal, three instillation hoses are slidably connected in the fixed disc, the circles of the three instillation hoses are equilateral triangle array, and the arc surfaces of the three instillation hoses are connected with each other, when the arc surfaces of the three instillation hoses are connected with each other, a cavity is formed between the three instillation hoses.

[0008] The further technical scheme of the utility model discloses, the fixed disc is away from the one side of animal and is fixedly connected with the flow guide plate, and the flow guide plate is located below the drip hose.

[0009] The further technical scheme of the utility model discloses, the adjusting part includes the first support plate and the second support plate that are hinged to the bottom surface of the fixed plate, and the bottom plate is arranged below the first support plate and the second support plate, the first support plate is located below the leg of the animal, the second support plate is located below the head of the animal, and the bottom end of the first support plate and the second support plate can be translated along the length direction of the bottom plate.

[0010] The further technical scheme of the utility model discloses, the drive part includes the sliding slot that is set up on the bottom plate, the first sliding block and the second sliding block are slidably connected in the sliding slot, and the bottom end of the first sliding block is hinged with the first support plate, the bottom end of the second sliding block is hinged with the second support plate, the first sliding block and the second sliding block are all screw-connected with the screw rod, the left and right sides of the bottom plate are all provided with the rotary drive part, and the output end of the two rotary drive parts all extends into the sliding slot and is fixedly connected with the two screw rods respectively.

[0011] The further technical scheme of the utility model discloses, the rotary drive part is servo motor.

[0012] The utility model discloses the beneficial effect is:

[0013] When needing to flush the nasal cavity, the drive part is moved down through the adjusting fixed plate at the end of the head of the animal, at this time, the head position of the animal is lower than the leg position, the fixed pipe and the drip hose are inserted into the nasal cavity, the physiological saline is injected into the nasal cavity through the drip hose, the nasal cavity is flushed, the waste water and secretion after flushing can be discharged from the nasal cavity through the cavity, so that the nasal cavity can be conveniently cleaned, after cleaning, the medicine is dropped into the trachea through the drip hose, so that the dropping experiment can be conveniently carried out, the secretion in the nasal cavity can be effectively prevented from entering the trachea, and the safety of the experiment is improved. ACCURATE DRAWINGS

[0014] Figure 1 It is the front view in the specific embodiment of the utility model.

[0015] Figure 2 It is the right view in the specific embodiment of the utility model.

[0016] Figure 3 It is the structure right view of the insertion part in the specific embodiment of the utility model.

[0017] In the figure: 1, fixed part; 11, fixed plate; 12, belt; 2, insertion part; 21, fixed disc; 22, fixed tube; 23, infusion hose; 24, cavity; 25, guide plate; 3, adjusting part; 31, first support plate; 32, second support plate; 33, bottom plate; 4, driving part; 41, sliding groove; 42, first sliding block; 43, second sliding block; 44, screw rod; 45, rotary driving piece. DETAILED DESCRIPTION

[0018] The specific embodiments of the utility model will be further described below in combination with the drawings.

[0019] As Figures 1-3 shown, an experimental animal tracheal infusion device, including fixed part 1, for the limbs of animals are fixed, easy to drip infusion experiment on animals, and the angle of fixed part 1 is adjusted, so as to realize when the animal is fixed, the angle of the animal can be adjusted, so that the head position is higher than the leg position, or the leg position is higher than the head position, the fixed part 1 is provided with insertion part 2, the insertion part 2 can be inserted into the nasal cavity of the animal, so as to pour the medicine into the trachea of the animal, and the physiological saline can be injected into the nasal cavity through the insertion part 2, the nasal cavity is cleaned, to prevent the secretion from entering the trachea with the medicine, when the medicine is dripped, the fixed part 1 is adjusted to the position that the head position of the animal is higher than the leg position, the medicine can be easily entered into the trachea, when the nasal cavity is cleaned, the fixed part 1 is adjusted to the position that the leg position is higher than the head position, the physiological saline can be effectively prevented from entering the trachea, and the physiological saline can be easily discharged, the subsequent medicine can be easily dripped, the lower of the fixed part 1 is provided with adjusting part 3, for adjusting the angle of the fixed part 1, so as to adjust the angle of the animal according to the use condition.

[0020] As Figure 1 and Figure 2 shown, the fixed part 1 includes a fixed plate 11, the fixed part 1 is provided with four belts 12, the limbs of the animals are fixed through the belts 12, so that the animals can be easily fixed on the fixed plate 11, when the end of the fixed plate 11 located at the leg of the animal moves downward, the head position of the animal is higher than the leg position, so that the animal can be easily dripped, when the end of the fixed plate 11 located at the head of the animal moves downward, the leg position of the animal is higher than the head position, so that the nasal cavity of the animal can be easily washed, to prevent the physiological saline from entering the trachea.

[0021] As Figures 1-3As shown, the insertion part 2 comprises a fixed disc 21 fixedly connected to the fixed plate 11, the fixed disc 21 is located on one side of the animal head, three infusion tubes 23 are slidably connected in the fixed disc 21, the circular shape of the three infusion tubes 23 is in equilateral triangle array, and the arc surfaces of the three infusion tubes 23 are connected with each other, when the arc surfaces of the three infusion tubes 23 are connected with each other, a cavity 24 is formed between the three infusion tubes 23, after the physiological saline is injected into the nasal cavity through the infusion tube 23, the nasal cavity can be flushed, the waste water after flushing can be discharged from the nasal cavity through the cavity 24, and the secretions can also be discharged with the waste water, after cleaning, the medicine is dropped into the trachea through the infusion tube 23, so that the dropping can be conveniently carried out, and the secretions can be prevented from entering the trachea with the medicine, thereby reducing the safety hidden danger, the guide plate 25 is fixedly connected to the side of the fixed disc 21 away from the animal, and the guide plate 25 is located below the infusion tube 23, so that the discharged waste water can be guided and collected.

[0022] As shown in Figure 1 and Figure 2 , the adjusting part 3 comprises a first support plate 31 and a second support plate 32 hinged to the bottom surface of the fixed plate 11, a bottom plate 33 is arranged below the first support plate 31 and the second support plate 32, the first support plate 31 is located below the leg of the animal, and the second support plate 32 is located below the head of the animal, the bottom ends of the first support plate 31 and the second support plate 32 can translate along the length direction of the bottom plate 33, when the high edge of the first support plate 31 is not perpendicular to the long edge of the fixed plate 11, one end of the fixed plate 11 located at the leg of the animal will move downward, when the high edge of the second support plate 32 is not perpendicular to the long edge of the fixed plate 11, one end of the fixed plate 11 located at the head of the animal will move downward, so as to adjust the positions of the two ends of the fixed plate 11.

[0023] As shown in Figure 1 and Figure 2 , the driving part 4 comprises a sliding groove 41 opened in the bottom plate 33, a first sliding block 42 and a second sliding block 43 are slidably connected in the sliding groove 41, the first sliding block 42 is hinged to the bottom end of the first support plate 31, the second sliding block 43 is hinged to the bottom end of the second support plate 32, a lead screw 44 is threadedly connected in each of the first sliding block 42 and the second sliding block 43, rotating driving members 45 are arranged on the left and right sides of the bottom plate 33, the output ends of the two rotating driving members 45 extend into the sliding groove 41 and are fixedly connected with the two lead screws 44 respectively, the rotating driving member 45 is a servo motor, when the rotating driving member 45 is started, the lead screw 44 can be driven to rotate, when the lead screw 44 rotates, the bottom ends of the second support plate 32 and the first support plate 31 can be driven to move, so that the angle of the fixed plate 11 can be conveniently adjusted.

[0024] Working principle: first, the animal is fixed on the fixed part 1, when the nasal cavity needs to be washed, the driving part 4 is started, the driving part 4 moves down through the adjusting fixed plate 11 at the end of the animal's head, at this time, the position of the animal's head is lower than that of the leg, then the fixed tube 22 and the infusion hose 23 are inserted into the nasal cavity, the physiological saline is injected into the nasal cavity through the infusion hose 23, the nasal cavity is washed, the waste water and the secretion after washing can be discharged from the nasal cavity through the cavity 24, so that the nasal cavity can be conveniently cleaned, after cleaning, the medicine is dropped into the trachea through the infusion hose 23, so that the dropping experiment can be conveniently carried out, the secretion in the nasal cavity can be effectively prevented from entering the trachea, and the safety of the experiment is improved.

[0025] It is apparent for those skilled in the art that the present application is not limited to the details of the above exemplary embodiments, but can be implemented in other concrete forms without departing from the spirit or essential characteristics of the present application. Therefore, the embodiments should be considered in all aspects as illustrative and not restrictive, and the scope of the present application is defined by the appended claims rather than the above description, and it is intended to encompass all changes falling within the meaning and scope of the equivalent elements of the claims. Any reference signs in the claims should not be considered as limiting the involved claims.

[0026] In addition, it should be understood that, although the present specification is described in terms of embodiments, not every embodiment contains only one independent technical solution, and the description of the specification is only for the sake of clarity, and those skilled in the art should consider the specification as a whole, and the technical solutions in each embodiment can be appropriately combined to form other embodiments that those skilled in the art can understand.

Claims

1. A tracheal drip device for laboratory animals, characterized in that: Includes a fixing part (1); used to fix the limbs of an animal, and the angle of the fixing part (1) can be adjusted so that the angle of the animal can be adjusted; Insertion part (2): It is provided on the fixing part (1). The insertion part (2) can be inserted into the nasal cavity of the animal, thereby dripping the medicine into the animal's trachea, and can also inject physiological saline into the nasal cavity through the insertion part (2). Adjustment part (3): Located below the fixing part (1), it is used to adjust the angle of the fixing part (1) so as to adjust the angle of the animal according to the usage situation and clean the nasal cavity. When administering medicine, the fixing part (1) is adjusted to the position of the animal's head higher than its legs. When cleaning the nasal cavity, the fixing part (1) is adjusted to the position of the legs higher than the head.

2. The experimental animal tracheal drip device according to claim 1, characterized in that, The fixing part (1) includes a fixing plate (11) and four straps (12) are provided on the fixing part (1) to fix the animal's limbs.

3. The experimental animal tracheal drip device according to claim 2, characterized in that, The insertion part (2) includes a fixing plate (21) fixedly connected to the fixing plate (11). The fixing plate (21) is located on one side of the animal's head. Three drip tubes (23) are slidably connected inside the fixing plate (21). The circles of the three drip tubes (23) are arranged in an equilateral triangle array, and the arc surfaces of the three drip tubes (23) are connected to each other. When the arc surfaces of the three drip tubes (23) are connected to each other, a cavity (24) will be formed between the three drip tubes (23).

4. The experimental animal tracheal drip device according to claim 3, characterized in that, A guide plate (25) is fixedly connected to the side of the fixed plate (21) away from the animal, and the guide plate (25) is located below the drip tube (23).

5. The experimental animal tracheal drip device according to claim 4, characterized in that, The adjustment part (3) includes a first support plate (31) and a second support plate (32) hinged to the bottom surface of the fixed plate (11). A base plate (33) is provided below the first support plate (31) and the second support plate (32). The first support plate (31) is located below the animal's legs, and the second support plate (32) is located below the animal's head. The bottom ends of the first support plate (31) and the second support plate (32) can be translated along the length direction of the base plate (33).

6. The experimental animal tracheal drip device according to claim 5, characterized in that, The drive unit (4) includes a slide groove (41) opened on the base plate (33). A first slider (42) and a second slider (43) are slidably connected in the slide groove (41). The first slider (42) is hinged to the bottom end of the first support plate (31), and the second slider (43) is hinged to the bottom end of the second support plate (32). A lead screw (44) is threaded into both the first slider (42) and the second slider (43). Rotary drive members (45) are provided on both the left and right sides of the base plate (33), and the output ends of the two rotary drive members (45) extend into the slide groove (41) and are fixedly connected to the two lead screws (44) respectively.

7. The experimental animal tracheal drip device according to claim 6, characterized in that, The rotary drive (45) is a servo motor.