Reagent bin for full-automatic chemiluminescence immunoassay analyzer

By employing a dual-layer turntable structure and automated operation methods, the problem of low efficiency in reagent compartments for large-capacity and high-speed assisted sample addition has been solved. Automatic loading and unloading of reagent kits has been achieved, improving the operational efficiency and human-computer interaction convenience of the fully automated chemiluminescence immunoassay analyzer.

CN223711618UActive Publication Date: 2025-12-23SUZHOU HYBIOME BIOMEDICAL ENG CO LTD
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Patent Information

Application Number
CN202423124548.5
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-12-18
Publication Date
2025-12-23
Estimated Expiration
2034-12-18

AI Technical Summary

Technical Problem

Existing fully automated chemiluminescence immunoassay analyzers suffer from inertia issues in reagent compartments regarding large-capacity and high-speed assisted sample addition, resulting in low operational efficiency. Furthermore, manual loading and unloading of reagent kits is labor-intensive and inconvenient.

Method used

It adopts a double-layer turntable structure, including an outer turntable and an inner turntable, combined with a drive frame, a Y-axis drive mechanism, a reagent kit barcode scanner, a mechanical gripper, and a Z-axis drive mechanism to realize automatic loading and unloading of reagent kits and meet the high-speed auxiliary sample dispensing function.

Benefits of technology

The automated operation of the reagent kits was achieved, which improved the efficiency of the reagent compartment, reduced the intensity of manual labor, and optimized the instrument layout design.

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Abstract

The utility model discloses a reagent bin for a full-automatic chemiluminescence immunoassay analyzer, which relates to the field of reagent bins and comprises a base, a reagent bin body is mounted on one side of the top of the base, and the top of an inner cavity of the reagent bin body is rotatably connected with an outer ring turntable and an inner ring turntable. A Y-axis driving mechanism, a kit code scanning gun, a mechanical gripper, a Z-axis driving mechanism and an X-axis driving mechanism are arranged at the top of the feeding and discharging assembly. According to the reagent bin for the full-automatic chemiluminescence immunoassay analyzer, the reagent bin rotating disc comprises the outer ring rotating disc and the inner ring rotating disc, the outer ring rotating disc and the inner ring rotating disc can independently rotate so as to meet the high-speed auxiliary sample adding function, meanwhile, automatic loading of a kit can be achieved, the kit only needs to be manually placed on the kit, and the kit can be automatically loaded. The mechanical gripper can be matched with the kit code scanning gun to complete code scanning and loading, and empty kits can be taken out of the reagent bin body to be directly discarded.
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Description

Technical Field

[0001] This utility model relates to the field of reagent storage, and in particular to a reagent storage for a fully automated chemiluminescence immunoassay analyzer. Background Technology

[0002] A default requirement for high-throughput fully automated chemiluminescence immunoassay analyzers is that a single instrument can test more items, carrying reagents for more than 30 tests. A typical Roche 801 instrument can carry 47 items. This places two demands on the reagent compartment of high-throughput instruments: efficient reagent needle aspiration and a larger reagent capacity.

[0003] In addition to providing a refrigerated environment for the reagents, the existing rotary reagent compartment also positions the corresponding reagents to the sampling port of the reagent needle by rotation, assisting the reagent needle in aspirating the reagents. Essentially, it breaks down the sampling action of the reagent needle into the action of two parts, thereby improving the efficiency of the instrument.

[0004] To meet the requirement for larger reagent capacity, a natural extension of the approach is to increase the size of the disc-shaped reagent compartment. However, this presents two problems: First, the inertia of the disc increases exponentially with its diameter, placing more stringent demands on its high-speed control, making it unable to meet the auxiliary sample dispensing function of high-throughput, high-speed instruments. Second, a single-ring arrangement of reagents leads to wasted space in the central area of ​​the disc. Of course, reagents can be arranged in two or more rings, but this still cannot solve the problem of excessive overall inertia that prevents the high-speed auxiliary sample dispensing function from being met.

[0005] In addition, with the increase in reagent capacity, the existing manual loading and unloading of reagents and empty reagent kits has two problems: on the one hand, it is labor-intensive; on the other hand, the reagent compartment interface must be easy for personnel to operate, otherwise it is inconvenient to load reagents and unload empty reagent kits, which limits the layout design of the instrument.

[0006] Therefore, it is necessary to propose a reagent compartment for a fully automated chemiluminescence immunoassay analyzer to solve the above problems. Utility Model Content

[0007] The main objective of this invention is to provide a reagent compartment for a fully automated chemiluminescence immunoassay analyzer, which can effectively solve the problems in the background art.

[0008] To achieve the above objectives, the technical solution adopted by this utility model is as follows:

[0009] A reagent compartment for a fully automated chemiluminescence immunoassay analyzer includes a base, a reagent compartment body is mounted on one side of the top of the base, a compartment door is movably connected to the top of the reagent compartment body, and an outer ring turntable and an inner ring turntable are rotatably connected to the top of the inner cavity of the reagent compartment body, with reagent kit mounting slots opened on the top of both the outer ring turntable and the inner ring turntable.

[0010] The top of the base is equipped with a loading and unloading assembly, and the top of the loading and unloading assembly is movably connected to a drive frame. The top of the loading and unloading assembly is provided with a Y-axis drive mechanism, a reagent kit barcode scanner, a mechanical gripper, a Z-axis drive mechanism, and an X-axis drive mechanism.

[0011] Preferably, a feeding compartment is provided on the side of the top of the reagent compartment body, and a drive motor is installed on the top of the reagent compartment body. The drive motor is connected to the outer wall of the compartment door through a drive shaft, and the size of the compartment door and the feeding compartment are compatible.

[0012] Preferably, a fixed shaft is installed in the center of the inner cavity of the reagent chamber, and an outer ring drive assembly is installed on one side of the bottom of the inner cavity of the reagent chamber. The outer ring drive assembly includes an outer ring servo motor, a first gear, a second gear, and an outer ring rotating shaft. The outer ring rotating shaft is rotatably connected to the outer wall of the inner ring rotating shaft. The top of the servo motor is installed at the bottom of the first gear through the first rotating shaft. The second gear is installed at the bottom of the outer wall of the outer ring rotating shaft. The first gear and the second gear mesh with each other. The outer ring rotating shaft is installed at the bottom of the outer ring turntable.

[0013] Preferably, an inner ring drive assembly is installed on the other side of the bottom of the base cavity. The inner ring drive assembly includes an inner ring servo motor, a belt, a first pulley, a second pulley, and an inner ring rotating shaft. The inner ring rotating shaft is rotatably connected to the outer wall of a fixed shaft. The top of the inner ring servo motor is mounted on the bottom of the first pulley via a second rotating shaft. The belt is mounted on the outer walls of the first and second pulleys. The second pulley is mounted on the outer wall of the inner ring rotating shaft. The inner ring rotating shaft is mounted on the bottom of the inner ring turntable.

[0014] Preferably, a Y-axis drive mechanism is installed on the top of the loading and unloading assembly, the drive frame is installed at the drive end of the Y-axis drive mechanism, and the reagent kit is placed on the top of the drive frame.

[0015] Preferably, the X-axis drive mechanism is installed on the top of the loading and unloading assembly, the Z-axis drive mechanism is installed on the drive end of the X-axis drive mechanism, and the bottom of the Z-axis drive mechanism is installed on the top of the mechanical gripper.

[0016] Compared with the prior art, the present invention has the following beneficial effects:

[0017] This fully automated chemiluminescence immunoassay analyzer uses a reagent compartment with an outer and inner rotating disc. Both discs can rotate independently to enable high-speed assisted sample loading. The inner rotating disc is located at the innermost part of the reagent compartment body, while the outer rotating disc is located at the outermost part. The axis between the outer and inner rotating discs is fixed. Through a drive frame, Y-axis drive mechanism, reagent barcode scanner, mechanical gripper, Z-axis drive mechanism, and X-axis drive mechanism, automatic reagent loading can be achieved. The operator only needs to place the reagent on the reagent tray, and the mechanical gripper, in conjunction with the reagent barcode scanner, can complete the scanning and loading, and can remove empty reagents from the reagent compartment body for direct disposal. Attached Figure Description

[0018] Figure 1 This is a schematic diagram of the overall structure of this utility model;

[0019] Figure 2 This is a cross-sectional view of the present invention;

[0020] Figure 3 This is a top view of the reagent compartment body of this utility model;

[0021] Figure 4 This is a schematic diagram of the loading and unloading assembly of this utility model.

[0022] In the diagram: 1. Base; 2. Reagent compartment body; 3. Feeding compartment; 4. Drive motor; 5. Compartment door; 6. Loading / unloading assembly; 7. Reagent kit; 8. Y-axis drive mechanism; 9. Reagent kit barcode scanner; 10. Mechanical gripper; 11. Z-axis drive mechanism; 12. X-axis drive mechanism; 13. Outer ring turntable; 14. Inner ring turntable; 15. Reagent kit mounting slot; 16. Outer ring drive assembly; 17. Inner ring drive assembly; 18. Outer ring rotating shaft; 19. Inner ring rotating shaft; 20. Fixed shaft. Detailed Implementation

[0023] To make the technical means, creative features, objectives and effects of this utility model easier to understand, the present utility model will be further described below in conjunction with specific embodiments. Example

[0024] like Figures 1-3As shown, a reagent compartment for a fully automated chemiluminescence immunoassay analyzer includes a base 1, a reagent compartment body 2 mounted on one side of the top of the base 1, a compartment door 5 movably connected to the top of the reagent compartment body 2, an outer ring turntable 13 and an inner ring turntable 14 rotatably connected to the top of the inner cavity of the reagent compartment body 2, and reagent kit mounting slots 15 opened on the top of both the outer ring turntable 13 and the inner ring turntable 14, a feeding compartment 3 opened on the side of the top of the reagent compartment body 2, a drive motor 4 mounted on the top of the reagent compartment body 2, the drive motor 4 being connected to the outer wall of the compartment door 5 via a drive shaft, the dimensions of the compartment door 5 and the feeding compartment 3 being adapted to each other, a fixed shaft 20 mounted in the center of the inner cavity of the reagent compartment body 2, and an outer ring drive assembly 16 mounted on one side of the bottom of the inner cavity of the reagent compartment body 2, the outer ring drive assembly 16 including an outer ring servo motor, a gear, and a... Gear 2, outer ring shaft 18, outer ring shaft 18 is rotatably connected to the outer wall of inner ring shaft 19, the top of the servo motor is mounted on the bottom of gear 1 through the first shaft, gear 2 is mounted on the bottom of the outer wall of outer ring shaft 18, gear 1 and gear 2 mesh with each other, outer ring shaft 18 is mounted on the bottom of outer ring turntable 13, inner ring drive assembly 17 is mounted on the other side of the bottom of the inner cavity of base 1, inner ring drive assembly 17 includes inner ring servo motor, belt, pulley 1, pulley 2, inner ring shaft 19, inner ring shaft 19 is rotatably connected to the outer wall of fixed shaft 20, the top of inner ring servo motor is mounted on the bottom of pulley 1 through the second shaft, belt is mounted on the outer walls of pulley 1 and pulley 2, pulley 2 is mounted on the outer wall of inner ring shaft 19, inner ring shaft 19 is mounted on the bottom of inner ring turntable 14. Example

[0025] like Figure 1 , Figure 4 As shown, a reagent compartment for a fully automated chemiluminescence immunoassay analyzer includes a base 1 with a loading / unloading assembly 6 mounted on top. A drive frame 21 is movably connected to the top of the loading / unloading assembly 6. The top of the loading / unloading assembly 6 is equipped with a Y-axis drive mechanism 8, a reagent scanner 9, a mechanical gripper 10, a Z-axis drive mechanism 11, and an X-axis drive mechanism 12. The Y-axis drive mechanism 8 is mounted on the top of the loading / unloading assembly 6, and the drive frame 21 is mounted at the drive end of the Y-axis drive mechanism 8. A reagent kit 7 is placed on the top of the drive frame 21. The X-axis drive mechanism 12 is mounted on the top of the loading / unloading assembly 6, and the Z-axis drive mechanism 11 is mounted at the drive end of the X-axis drive mechanism 12. The bottom of the Z-axis drive mechanism 11 is mounted on the top of the mechanical gripper 10.

[0026] The reagent compartment turntable includes an outer turntable 13 and an inner turntable 14. Both the outer turntable 13 and the inner turntable 14 can rotate independently to meet the high-speed auxiliary sample dispensing function. The inner rotating shaft 19 is located at the innermost side of the reagent compartment body 2; the outer rotating shaft 18 is located at the outermost layer of the reagent compartment body 2; the fixed shaft 20 is between the outer rotating shaft 18 and the inner rotating shaft 19. Through the set drive frame 21, Y-axis drive mechanism 8, reagent barcode scanner 9, mechanical gripper 10, Z-axis drive mechanism 11 and X-axis drive mechanism 12, the automatic loading of reagent kit 7 can be realized. The operator only needs to place the reagent kit 7 on the reagent compartment body 2. The mechanical gripper 10 can work with the reagent barcode scanner 9 to complete the scanning and loading, and can take the empty reagent kit out of the reagent compartment body 2 and discard it directly.

[0027] The foregoing has shown and described the basic principles, main features, and advantages of this utility model. Those skilled in the art should understand that this utility model is not limited to the above embodiments. The embodiments and descriptions in the specification are merely illustrative of the principles of this utility model. Various changes and modifications can be made to this utility model without departing from its spirit and scope, and all such changes and modifications fall within the scope of the claims. The scope of protection of this utility model is defined by the appended claims and their equivalents.

Claims

1. A reagent compartment for a fully automated chemiluminescence immunoassay analyzer, comprising a base (1), characterized in that: A reagent compartment body (2) is installed on one side of the top of the base (1). A compartment door (5) is movably connected to the top of the reagent compartment body (2). An outer ring turntable (13) and an inner ring turntable (14) are rotatably connected to the top of the inner cavity of the reagent compartment body (2). A reagent kit installation slot (15) is opened on the top of both the outer ring turntable (13) and the inner ring turntable (14). The top of the base (1) is equipped with a loading and unloading assembly (6), and the top of the loading and unloading assembly (6) is movably connected to a drive frame (21). The top of the loading and unloading assembly (6) is provided with a Y-axis drive mechanism (8), a reagent kit barcode scanner (9), a mechanical gripper (10), a Z-axis drive mechanism (11), and an X-axis drive mechanism (12).

2. The reagent compartment for a fully automated chemiluminescence immunoassay analyzer according to claim 1, characterized in that: A feeding chamber (3) is provided on the side of the top of the reagent chamber body (2). A drive motor (4) is installed on the top of the reagent chamber body (2). The drive motor (4) is connected to the outer wall of the chamber door (5) through a drive shaft. The dimensions of the chamber door (5) and the feeding chamber (3) are compatible.

3. The reagent compartment for a fully automated chemiluminescence immunoassay analyzer according to claim 1, characterized in that: A fixed shaft (20) is installed in the center of the inner cavity of the reagent chamber body (2). An outer ring drive assembly (16) is installed on one side of the bottom of the inner cavity of the reagent chamber body (2). The outer ring drive assembly (16) includes an outer ring servo motor, gear one, gear two, and an outer ring rotating shaft (18). The outer ring rotating shaft (18) is rotatably connected to the outer wall of the inner ring rotating shaft (19). The top of the servo motor is installed at the bottom of gear one through the first rotating shaft. Gear two is installed at the bottom of the outer wall of the outer ring rotating shaft (18). Gear one and gear two mesh with each other. The outer ring rotating shaft (18) is installed at the bottom of the outer ring turntable (13).

4. The reagent compartment for a fully automated chemiluminescence immunoassay analyzer according to claim 1, characterized in that: An inner ring drive assembly (17) is installed on the other side of the bottom of the inner cavity of the base (1). The inner ring drive assembly (17) includes an inner ring servo motor, a belt, a pulley one, a pulley two, and an inner ring rotating shaft (19). The inner ring rotating shaft (19) is rotatably connected to the outer wall of the fixed shaft (20). The top of the inner ring servo motor is installed at the bottom of the pulley one through the second rotating shaft. The belt is installed on the outer walls of the pulley one and the pulley two. The pulley two is installed on the outer wall of the inner ring rotating shaft (19). The inner ring rotating shaft (19) is installed at the bottom of the inner ring turntable (14).

5. The reagent compartment for a fully automated chemiluminescence immunoassay analyzer according to claim 1, characterized in that: The loading and unloading assembly (6) is equipped with a Y-axis drive mechanism (8) on top, and the drive frame (21) is installed at the drive end of the Y-axis drive mechanism (8). The reagent kit (7) is placed on the top of the drive frame (21).

6. The reagent compartment for a fully automated chemiluminescence immunoassay analyzer according to claim 1, characterized in that: The X-axis drive mechanism (12) is installed on the top of the loading and unloading assembly (6), the Z-axis drive mechanism (11) is installed on the drive end of the X-axis drive mechanism (12), and the bottom of the Z-axis drive mechanism (11) is installed on the top of the mechanical gripper (10).