Tetanus human immune globulin centrifugal device
By designing a combination of lid, centrifuge chamber, locking structure, pressing mechanism, limiting mechanism, and fixing mechanism, the problem of unstable centrifuge tube sealing cap in the centrifuge device was solved, achieving stable fixation of centrifuge tubes at high speeds, preventing liquid splashing, and ensuring the separation and purification effect of raw plasma.
Patent Information
- Application Number
- CN202423172635.8
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-12-20
- Publication Date
- 2025-12-26
- Estimated Expiration
- 2034-12-20
AI Technical Summary
In existing centrifugation devices, the centrifuge tube caps are unstable when separating and purifying immunoglobulin raw material plasma, causing liquid to splash out and affecting the separation and purification effect.
A centrifuge device for tetanus human immunoglobulin was designed. Through the cooperation of a lid, centrifuge chamber, locking structure, pressure mechanism, limiting mechanism and fixing mechanism, the centrifuge tube sealing cap is stably fixed to prevent liquid from splashing out.
At high speeds, the centrifuge tube caps are less prone to instability, preventing liquid splashing and ensuring the separation and purification of raw plasma.
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Figure CN223717376U_ABST
Abstract
Description
TECHNICAL FIELD
[0001] The utility model relates to centrifugal device technical field, specifically, relate to a kind of tetanus human immunoglobulin centrifugal device. BACKGROUND
[0002] Tetanus human immunoglobulin is an important biological pharmaceutical product, mainly used for treating and preventing tetanus. In the preparation process, the raw material plasma needs to be centrifuged to separate and purify immunoglobulin, so tetanus human immunoglobulin centrifugal device is needed.
[0003] The existing centrifugal device is not convenient for fixing the sealing cover of the centrifugal tube when separating and purifying the immunoglobulin raw material plasma. When the centrifugal device rotates at high speed, the sealing cover of the centrifugal tube may not be stable, which may cause liquid to splash out and affect the separation and purification of the raw material plasma. Therefore, a tetanus human immunoglobulin centrifugal device is needed to solve the above problems. UTILITY MODEL CONTENT
[0004] The utility model aims to provide a kind of tetanus human immunoglobulin centrifugal device, solve the problem that the existing centrifugal device in prior art separates and purifies immunoglobulin raw material plasma, because centrifugal device is not convenient for fixing the sealing cover of the centrifugal tube, when the centrifugal device rotates at high speed, the sealing cover of the centrifugal tube may not be stable, which may cause liquid to splash out and affect the separation and purification of the raw material plasma.
[0005] The utility model provides the following technical scheme: a kind of tetanus human immunoglobulin centrifugal device, including centrifugal box, the top end of the centrifugal box is hinged with lid, the inside bottom of the centrifugal box is fixedly connected with annular plate, the top of the annular plate is provided with annular groove, the inner side of the annular plate is equipped with rotating mechanism, the bottom of the lid is provided with installation slot, the inside of the installation slot is equipped with abutting mechanism, the bottom of the lid is provided with rectangular slot, the inside of the rectangular slot is equipped with limiting mechanism for fixing abutting mechanism, the outer side end of the lid is equipped with fixing mechanism for fixing limiting mechanism.
[0006] As a preferred embodiment of the above technical solution, the rotating mechanism includes a motor, the motor is fixedly installed on the inner wall of the annular plate, the output end of the motor is provided with a rotating rod, the outer end of the rotating rod is fixedly connected with a centrifugal disc, and a plurality of placing grooves are formed in the top end of the centrifugal disc.
[0007] As a preferred embodiment of the above technical solution, the inside bottom of each placing groove is provided with a non-slip pad, and the inner wall of each placing groove is fixedly connected with a non-slip ring.
[0008] As the preferred technical scheme of the above, the bottom end of the centrifugal disc is fixedly connected with a plurality of round rods, the bottom end of each round rod is rotatably provided with a ball, and each ball is located in an annular groove.
[0009] As the preferred technical scheme of the above, the pressing mechanism comprises a pressing ring plate, the pressing ring plate is rotatably arranged at the inner top end of the mounting groove, the bottom end of the pressing ring plate is fixedly connected with a plurality of pressing plates, and the bottom end of the pressing ring plate is provided with an insertion slot at the side end of each pressing plate.
[0010] As the preferred technical scheme of the above, the limiting mechanism comprises a rectangular plate, the rectangular plate is inserted into the rectangular groove, the side end of the rectangular plate is fixedly connected with an insertion plate, the insertion plate is inserted into the insertion slot, the side end of the rectangular plate is fixedly connected with a pull rod, the pull rod is inserted into the outer side end of the box cover, the outer end of the pull rod is sleeved with a spring, one end of the spring is fixedly connected to the side end of the rectangular plate, and the other end of the spring is fixedly connected to the inner side end of the rectangular groove.
[0011] As the preferred technical scheme of the above, the fixing mechanism comprises two groups of supports, the two groups of supports are fixedly connected to the outer side end of the box cover, a screw sleeve is fixedly connected between the side ends of the two groups of supports, the side end of the pull rod is rotatably provided with a screw rod, the screw rod is threadedly connected in the screw sleeve, and the side end of the screw rod is fixedly connected with a rotating plate.
[0012] Compared with the prior art, the utility model has the advantages of:
[0013] The utility model discloses a box cover, centrifugal box, locking structure, pressing mechanism, limiting mechanism and the cooperation of fixing mechanism, through the placing of every centrifugal tube in every placing groove, through the spring toping rectangular plate and drive insertion plate and insert into any one insertion slot, can make every pressing plate just align every placing groove top, when the box cover closes between the locking structure and centrifugal box, every pressing plate can just press in the top of centrifugal tube, at this moment can press the sealing cover of every centrifugal tube top, then through the pull of rotating plate, can drive pull rod to move, at this moment pull rod drives rectangular plate and insertion plate to move, makes insertion plate leave insertion slot, through the continuous pull of rotating plate, the rotation of rotating plate can drive screw rod and threadedly connected in screw sleeve, can fix the position of pull rod and insertion plate, avoids the influence of insertion plate to the rotation of pressing ring plate, when starting motor drives rotating rod and centrifugal disc to rotate, can drive every centrifugal tube to rotate, because the pressing plate presses in the top of centrifugal tube, centrifugal tube rotates and can drive whole pressing ring plate to rotate, at this moment because pressing ring plate and pressing plate press the sealing cover of centrifugal tube top, therefore when centrifugal device speed is fast, does not easily lead to the unstable situation of centrifugal tube sealing cover, thereby avoids the liquid splash, avoids the influence of raw material blood plasma separation and purification. BRIEF DESCRIPTION OF DRAWINGS
[0014] Figure 1 It is a whole structure schematic view of a tetanus human immunoglobulin centrifugal device;
[0015] Figure 2 It is a bottom exploded structure schematic view of a tetanus human immunoglobulin centrifugal device;
[0016] Figure 3 It is Figure 2 It is a partial enlarged structure schematic view of A in the middle;
[0017] Figure 4 It is a sectional structure schematic view of a tetanus human immunoglobulin centrifugal device.
[0018] In the figure: 1, centrifugal box; 2, box cover; 201, mounting groove; 202, rectangular groove; 3, annular plate; 301, annular groove; 4, rotating mechanism; 401, motor; 402, rotating rod; 403, centrifugal disc; 404, placing groove; 405, anti-skid pad; 406, anti-skid ring; 407, round rod; 408, ball; 5, pressing mechanism; 501, pressing annular plate; 502, pressing plate; 503, insertion slot; 6, limiting mechanism; 601, rectangular plate; 602, insertion plate; 603, pull rod; 604, spring; 7, fixing mechanism; 701, support; 702, screw sleeve; 703, screw rod; 704, rotating plate. DETAILED DESCRIPTION
[0019] The technical solutions in the embodiments of the utility model will be clearly and completely described below with reference to the drawings in the embodiments of the utility model.
[0020] As Figures 1-4 shown, the utility model provides a technical scheme: a tetanus human immunoglobulin centrifugal device, including centrifugal box 1, the top end of centrifugal box 1 is hinged with box cover 2, and the box cover 2 and centrifugal box 1 are opened and closed through the existing locking structure (not shown), the inside bottom end of centrifugal box 1 is fixedly connected with annular plate 3, the top end of annular plate 3 is provided with annular groove 301, the inner side of annular plate 3 is equipped with rotating mechanism 4, the bottom end of box cover 2 is provided with mounting groove 201, the inside of mounting groove 201 is equipped with pressing mechanism 5, the bottom end of box cover 2 is provided with rectangular groove 202, the inside of rectangular groove 202 is equipped with limiting mechanism 6 for fixing pressing mechanism 5, and the outer side end of box cover 2 is equipped with fixing mechanism 7 for fixing limiting mechanism 6, in the implementation, the cooperation of box cover 2, centrifugal box 1, locking structure, pressing mechanism 5, limiting mechanism 6 and fixing mechanism 7 is convenient for pressing and fixing the sealing cover of the top end of centrifugal tube, so when the centrifugal device speed is fast, the sealing cover of centrifugal tube is not prone to unstable sealing, thereby avoiding liquid splashing out and avoiding affecting the separation and purification of raw material plasma.
[0021] As an implementation manner in the embodiment, as shown in the figure, Figure 4 The rotating mechanism 4 includes a motor 401 fixedly installed on the inner wall of the annular plate 3, the output end of the motor 401 is installed with a rotating rod 402, the outer end of the rotating rod 402 is fixedly connected with a centrifugal disc 403, the top end of the centrifugal disc 403 is provided with a plurality of placing grooves 404, the inner bottom end of each placing groove 404 is installed with an anti-skid pad 405, the inner wall of each placing groove 404 is fixedly connected with an anti-skid ring 406, the bottom end of the centrifugal disc 403 is fixedly connected with a plurality of round rods 407, the bottom end of each round rod 407 is rotatably provided with a ball 408, and each ball 408 is located in the annular groove 301. In the implementation, after each centrifugal tube is placed in each placing groove 404 until the bottom of the centrifugal tube contacts the anti-skid pad 405, the centrifugal tube is arranged in cooperation with the anti-skid pad 405 and the anti-skid ring 406, which can improve the stability of the centrifugal tube in the placing groove 404, so that the separation and purification of the immunoglobulin raw plasma in the centrifugal tube is more stable. When the motor 401 is started to drive the rotating rod 402 and the centrifugal disc 403 to rotate, each centrifugal tube can be driven to rotate. When the centrifugal disc 403 rotates, the round rod 407 can be driven to rotate, and the round rod 407 can drive the ball 408 to roll in the annular groove 301 after rotating, which improves the stability of the centrifugal disc 403 when rotating and reduces the friction force when the centrifugal disc 403 rotates, thereby facilitating the separation and purification of the tetanus human immunoglobulin in the centrifugal tube.
[0022] As an implementation manner in the embodiment, as shown in the figure, Figure 2 The pressing mechanism 5 includes a pressing ring plate 501 rotatably arranged at the inner top end of the mounting groove 201, the bottom end of the pressing ring plate 501 is fixedly connected with a plurality of pressing plates 502, and the bottom end of the pressing ring plate 501 is provided with an insertion slot 503 at the side end of each pressing plate 502. In the implementation, when the box cover 2 is closed through the locking structure between the centrifugal box 1, each pressing plate 502 can be pressed on the top end of the centrifugal tube, which can press and tighten the sealing cover at the top end of each centrifugal tube. Therefore, when the centrifugal device rotates at a high speed, the sealing cover of the centrifugal tube is not easy to be unstable, so as to avoid liquid splashing out and affecting the separation and purification of the raw plasma.
[0023] As an implementation manner in the embodiment, as shown in the figure, Figure 3As shown, the limiting mechanism 6 comprises a rectangular plate 601 inserted into the rectangular groove 202, the side end of the rectangular plate 601 is fixedly connected with an insertion plate 602 inserted into the insertion groove 503, the side end of the rectangular plate 601 is fixedly connected with a pull rod 603 inserted into the outside side end of the box cover 2, the outer end of the pull rod 603 is sleeved with a spring 604, one end of the spring 604 is fixedly connected to the side end of the rectangular plate 601, the other end of the spring 604 is fixedly connected to the inside side end of the rectangular groove 202, the fixing mechanism 7 comprises two groups of supports 701 fixedly connected to the outside side end of the box cover 2, the side ends of the two groups of supports 701 are fixedly connected with a screw sleeve 702, the side end of the pull rod 603 is rotatably provided with a screw rod 703 threaded into the screw sleeve 702, the side end of the screw rod 703 is fixedly connected with a rotating plate 704, in the implementation process, the spring 604 pushes the rectangular plate 601 to drive the insertion plate 602 to be inserted into any one of the insertion grooves 503, so that each pressing plate 502 is aligned with the top of each placement groove 404, so that when the box cover 2 is closed through the locking structure and the centrifugal box 1, each pressing plate 502 can be pressed on the top of the centrifugal tube, at this time, the sealing cover on the top of each centrifugal tube can be pressed tightly, then by pulling the rotating plate 704, the pull rod 603 can be moved, at this time, the pull rod 603 drives the rectangular plate 601 and the insertion plate 602 to move, so that the insertion plate 602 is separated from the insertion groove 503, at this time, the insertion plate 602 no longer limits the rotation of the pressing annular plate 501, at this time, by continuing to pull the rotating plate 704, when the threaded end of the screw rod 703 is located at the side end of the screw sleeve 702, the rotating plate 704 can drive the screw rod 703 to be screwed into the screw sleeve 702, so that the positions of the pull rod 603 and the insertion plate 602 can be fixed, avoiding the influence of the insertion plate 602 on the rotation of the pressing annular plate 501.
[0024] Working principle: after placing each centrifugal tube in each placing groove 404 until the bottom of the centrifugal tube contacts the non-slip pad 405, the centrifugal tube is set through the cooperation of the non-slip pad 405 and the non-slip ring 406, which can improve the stability of the centrifugal tube in the placing groove 404, so that the immunoglobulin raw material plasma in the centrifugal tube is more stable during separation and purification, the spring 604 pushes the rectangular plate 601 to drive the plug plate 602 to plug into any one of the plug slots 503, so that each pressing plate 502 is just aligned with the top end of each placing groove 404, so that each pressing plate 502 can just press on the top end of the centrifugal tube when the box cover 2 is closed through the locking structure between the centrifugal box 1, so that the sealing cover at the top end of each centrifugal tube can be pressed tightly, then by pulling the rotating plate 704, the pull rod 603 can be moved, at this time the pull rod 603 drives the rectangular plate 601 and the plug plate 602 to move, so that the plug plate 602 leaves the plug slot 503, at this time the plug plate 602 is no longer limited and fixed by the pressing ring, at this time by continuing to pull the rotating plate 704, when the threaded end of the screw rod 703 is located at the side end of the screw sleeve 702, the rotating plate 704 can drive the screw rod 703 to be screwed in the screw sleeve 702, so that the position of the pull rod 603 and the plug plate 602 can be fixed, avoiding the influence of the plug plate 602 on the rotation of the pressing ring plate 501, when the motor 401 is started to drive the rotating rod 402 and the centrifugal disc 403 to rotate, each centrifugal tube can be rotated, since the pressing plate 502 presses on the top end of the centrifugal tube, the centrifugal tube can drive the whole pressing ring plate 501 to rotate after rotating, at this time since the pressing ring plate 501 and the pressing plate 502 press and fix the sealing cover at the top end of the centrifugal tube, therefore when the centrifugal device rotates at high speed, it is not easy to cause the sealing cover of the centrifugal tube to be unstable, so as to avoid the liquid from spilling out and affecting the separation and purification of the raw material plasma.
[0025] The above examples are only used to illustrate the technical solutions of the present application, but not limit it.
Claims
1. A centrifuge device for tetanus human immunoglobulin, comprising a centrifuge box (1), the top end of which is hinged with a box cover (2), characterized in that: The inner bottom end of the centrifugal box (1) is fixedly connected with an annular plate (3), the top end of the annular plate (3) is provided with an annular groove (301), the inner side of the annular plate (3) is provided with a rotating mechanism (4), the bottom end of the box cover (2) is provided with a mounting groove (201), the inside of the mounting groove (201) is provided with a pressing mechanism (5), the bottom end of the box cover (2) is provided with a rectangular groove (202), the inside of the rectangular groove (202) is provided with a limiting mechanism (6) for fixing the pressing mechanism (5), and the outer side end of the box cover (2) is provided with a fixing mechanism (7) for fixing the limiting mechanism (6).
2. The human tetanus immunoglobulin centrifugal device according to claim 1, characterized in that: The rotating mechanism (4) comprises a motor (401), the motor (401) is fixedly installed on the inner wall of the annular plate (3), the output end of the motor (401) is provided with a rotating rod (402), the outer end of the rotating rod (402) is fixedly connected with a centrifugal disc (403), and the top end of the centrifugal disc (403) is provided with a plurality of placing grooves (404).
3. The human tetanus immunoglobulin centrifugation device according to claim 2, characterized in that: The inside of each placing groove (404) is provided with an anti-skid pad (405), and the inner wall of each placing groove (404) is fixedly connected with an anti-skid ring (406).
4. The human tetanus immunoglobulin centrifugal device according to claim 2, characterized in that: The bottom end of the centrifugal disc (403) is fixedly connected with a plurality of round rods (407), the bottom end of each round rod (407) is rotatably provided with a ball (408), and each ball (408) is located in the annular groove (301).
5. The human tetanus immunoglobulin centrifugal device according to claim 1, characterized in that: The pressing mechanism (5) comprises a pressing ring plate (501), the pressing ring plate (501) is rotatably arranged at the inner top end of the mounting groove (201), the bottom end of the pressing ring plate (501) is fixedly connected with a plurality of pressing plates (502), and the bottom end of the pressing ring plate (501) is provided with a slot (503) at the side end of each pressing plate (502).
6. The human tetanus immunoglobulin centrifugation device according to claim 5, characterized in that: The limiting mechanism (6) comprises a rectangular plate (601), the rectangular plate (601) is inserted into the rectangular groove (202), the side end of the rectangular plate (601) is fixedly connected with an insertion plate (602), the insertion plate (602) is inserted into the slot (503), the side end of the rectangular plate (601) is fixedly connected with a pull rod (603), the pull rod (603) is inserted into the outer side end of the box cover (2), the outer end of the pull rod (603) is sleeved with a spring (604), one end of the spring (604) is fixedly connected with the side end of the rectangular plate (601), and the other end of the spring (604) is fixedly connected with the inner side end of the rectangular groove (202).
7. The human tetanus immunoglobulin centrifugation device according to claim 6, characterized in that: The fixing mechanism (7) comprises two groups of supports (701), the two groups of supports (701) are fixedly connected with the outer side end of the box cover (2), the side ends of the two groups of supports (701) are fixedly connected with a threaded sleeve (702), the side end of the pull rod (603) is rotatably provided with a threaded rod (703), the threaded rod (703) is threadedly connected in the threaded sleeve (702), and the side end of the threaded rod (703) is fixedly connected with a rotating plate (704).