Focused ultrasonic heating treatment and monitoring device

Abstract

The utility model provides a focused ultrasound heating treatment and monitoring device, which comprises a treatment transducer and an imaging probe, and the treatment transducer and the imaging probe are integrated. Wherein the treatment transducer is used for focused ultrasonic treatment, and the imaging probe is used for detecting area imaging; a tissue section detected by the imaging probe comprises at least one focusing area center of the treatment transducer; according to the embodiment of the utility model, the integrated treatment transducer and imaging probe can perform real-time monitoring while treating a target object.

Description

TECHNICAL FIELD

[0001] The utility model relates to medical equipment technical field especially, relate to a kind of focused ultrasound heating treatment and monitoring device. BACKGROUND

[0002] In the treatment process, because focused ultrasound uses thermal effect to promote target tissue temperature, often cause some problems, for example, when treating face, due to the error of pre-judgment to treatment tissue, energy is applied to expression muscle, and face rigidity, bilateral asymmetry and other problems are caused.

[0003] To solve this problem, the device in the related art is used in conjunction with an ultrasound imaging probe when using focused ultrasound technology, that is, after measuring the information of the tissue to be treated using the probe, treatment is performed to avoid the above problems. However, the above technical solution still has some shortcomings, because the treatment head and the imaging probe are two separate probes, it is difficult to achieve repeated positioning, resulting in the treatment area being out of sync with the measured spatial position.

[0004] Therefore, the focused ultrasound heating treatment and monitoring device in the related art has the technical problem that the focused ultrasound heating treatment area and the monitoring area are out of sync in spatial position. SUMMARY

[0005] The utility model provides a kind of focused ultrasound heating treatment and monitoring device, to solve the defect that focused ultrasound heating treatment area and monitoring area spatial position are out of sync in prior art, realize the focused ultrasound heating treatment and monitoring device of diagnosis and treatment integration, to carry out real-time monitoring to treatment area.

[0006] The utility model provides a kind of focused ultrasound heating treatment and monitoring treatment device, including following parts.Treatment transducer and imaging probe, wherein, the treatment transducer and the imaging probe are integrated as a whole;Wherein, the treatment transducer is used for focused ultrasound treatment, and the imaging probe is used for detecting area imaging;The tissue section obtained by the imaging probe detection includes the focus area center of at least one treatment transducer.

[0007] According to the focused ultrasound heating treatment and monitoring treatment device provided by the utility model, the treatment transducer includes: main transducer and at least one auxiliary transducer, wherein the relative position of the main transducer and at least one auxiliary transducer remains unchanged or moves in groups, so that the focus area center is relatively fixed with the transducer and the imaging probe in the tissue section.

[0008] The utility model provides a kind of focused ultrasound heating treatment and monitoring treatment device, the main transducer and at least one the auxiliary transducer are single point focusing transducer, line focusing transducer or at least one the single point focusing transducer and at least one the line focusing transducer of splicing.

[0009] The utility model provides a kind of focused ultrasound heating treatment and monitoring treatment device, the device further includes: external control circuit, the external control circuit is electrically connected with the treatment transducer and the imaging probe respectively, wherein, the external control circuit is used to distinguish the working time sequence of the treatment transducer and the imaging probe.

[0010] The utility model provides a kind of focused ultrasound heating treatment and monitoring treatment device, the device further includes: mechanical adjusting component, the mechanical adjusting component is connected with the treatment transducer and the imaging probe respectively, for the overall position movement of the treatment transducer and the imaging probe, wherein the overall position movement includes overall depth movement and overall horizontal movement.

[0011] The utility model provides a kind of focused ultrasound heating treatment and monitoring treatment device, the device further includes: hardware component, the hardware component includes circuit connection and data transmission module, and is electrically connected with the imaging probe, and the hardware component is used to divide the image data returned by the imaging probe into 2 groups of data.

[0012] The utility model provides a kind of focused ultrasound heating treatment and monitoring treatment device, 2 groups of data are used to convert into image data and ultrasonic radio frequency signal respectively.

[0013] The utility model provides a kind of focused ultrasound heating treatment and monitoring treatment device, the device further includes: host computer, the host computer is electrically connected with the hardware component, is used to process the ultrasonic radio frequency signal, to obtain the target information of the tissue section, wherein, the target information includes temperature, elasticity and acoustic attenuation.

[0014] The utility model provides a kind of focused ultrasound heating treatment and monitoring treatment device, the device further includes: multiple temperature sensors, wherein, the multiple temperature sensors are attached to the heating area of the treatment transducer, for detecting the real-time temperature of the heating area of the treatment transducer.

[0015] The utility model provides a kind of focused ultrasound heating treatment and monitoring treatment device, the imaging probe is inlaid in the center position of the treatment transducer.

[0016] The focusing ultrasonic heating treatment and monitoring device provided by the utility model, treatment transducer and imaging probe, wherein, treatment transducer and imaging probe are integrated; wherein, treatment transducer is used for focusing ultrasonic treatment, and imaging probe is used for detecting regional imaging; the tissue section obtained by imaging probe detection includes the focusing area center of at least one treatment transducer, thereby, through integrated treatment transducer and imaging probe, real-time monitoring can be carried out at the same time of treatment target object, other tissues can be avoided, and the accuracy of treatment area is ensured, and then the defect that the focusing ultrasonic heating treatment area and monitoring area spatial position are out of synchronization in the prior art is solved. BRIEF DESCRIPTION OF DRAWINGS

[0017] In order to more clearly illustrate the technical scheme in the utility model or the prior art, the drawings needed to be used in the embodiment or the prior art description will be simply introduced one by one below, and obviously, the drawings in the following description are some embodiments of the utility model, and other drawings can also be obtained by the drawings for the ordinary skilled in the art without creative labor.

[0018] Figure 1 It is the structural schematic diagram of the focusing ultrasonic heating treatment and monitoring treatment device provided by the utility model.

[0019] Figure 2 It is the top view schematic diagram of the transducer group of the focusing ultrasonic heating treatment and monitoring treatment device provided by the utility model.

[0020] Figure 3 It is the section schematic diagram of the transducer group of the focusing ultrasonic heating treatment and monitoring treatment device provided by the utility model.

[0021] Figure 4 It is the structural schematic diagram of interval time and duration provided by the utility model.

[0022] Figure 5 It is the signal feedback adjustment logic schematic diagram provided by the utility model. DETAILED DESCRIPTION

[0023] In order to make the purpose, technical scheme and advantages of the utility model more clear, the technical scheme in the utility model will be clearly and completely described below in conjunction with the drawings in the utility model, obviously, the described embodiment is a part of the embodiment of the utility model, not all the embodiment. Based on the embodiment in the utility model, all other embodiments obtained by the ordinary skilled in the art without creative labor belong to the scope of the utility model protection.

[0024] In the utility model embodiment, unless otherwise explicitly specified and limited, the terms "mounting", "connection", "connecting", "fixing" and the like should be understood in a broad sense, for example, can be fixed connection, or can be detachable connection, or can be integrated; can be mechanical connection, or can be electrical connection or can communicate with each other; can be directly connected, or can be indirectly connected through an intermediate medium; can make the internal connection of two elements or the interaction relationship of two elements. For those skilled in the art, the specific meaning of the above terms in the utility model embodiment can be understood according to the specific circumstances.

[0025] Focused ultrasound technology is widely used in medical devices. When ultrasound travels in a medium, it produces mechanical and cavitation effects. When the ultrasound wave penetrates or passes through the tissue, it can induce molecular oscillation in the body tissue due to reflection, scattering or absorption, thereby ablating adipose tissue. The broken fat cells release a large amount of triglycerides, which are hydrolyzed by lipases into free fatty acids and glycerol, which are gradually absorbed through their own capillaries and lymphatic vessels, and metabolized in the liver or other parts, gradually achieving the purpose of weight loss and body shaping. In addition, focused ultrasound technology is also a new type of non-invasive skin tightening and wrinkle removal method. By applying heat energy to the superficial aponeurotic system layer between the deep layer of the skin and the muscle tissue, the contraction and regeneration of collagen are promoted, thereby lifting the skin tissue and improving the problems of facial relaxation and wrinkles. By using transducers of different frequencies and focal lengths, different depths of treatment can be achieved, including fine line lightening, contour curve improvement and tissue tightness improvement.

[0026] During treatment, focused ultrasound often causes problems due to the use of thermal effects to raise the temperature of the target tissue. For example, when treating the face, the energy is applied to the expression muscles, causing facial stiffness, bilateral asymmetry and other problems. In order to solve this problem, some products currently use an ultrasound image probe during use. By measuring the information of the tissue to be treated using the probe, treatment can be performed, which can avoid the above problems.

[0027] However, the above technical solution still has many disadvantages. For example, since the treatment head and the image probe are two separate probes, it is difficult to achieve repeated positioning, i.e., the treatment area is not synchronized with the measured spatial position; and the image probe cannot work when the treatment head is working, and can only be used to see the condition of the target tissue when the treatment is paused. That is, the treatment area is not synchronized in time with the measured tissue information. The asynchronization of time and space makes it difficult for the image probe to give effective information of the treatment area in actual use, and it cannot monitor the treatment in real time, but can only play a preoperative examination role and cannot monitor the treatment state in real time.

[0028] Reference Figure 1 , Figure 1It is the structural schematic view of the focused ultrasound heating treatment and monitoring treatment device provided by the utility model, wherein, including imaging probe 101 and treatment transducer 102.

[0029] Treatment transducer 102 and imaging probe 101, wherein, treatment transducer 102 and imaging probe 101 are integrated as a whole;

[0030] Wherein, treatment transducer 102 is used for focused ultrasound treatment, and imaging probe 101 is used for detecting regional imaging;The tissue section obtained by imaging probe 101 detection includes at least one focused region center of treatment transducer 102.

[0031] In the embodiment of the utility model, for the integration of treatment transducer and imaging probe, it can be through the way of embedding of main transducer and imaging probe.For example, in order to ensure the imaging quality, the line array transducer with pitch 0.2 millimeter, 128 array elements is used, and its basic size is 5mm*26mm;The main transducer is single point focusing spherical self focusing transducer, and the aperture is 50mm;The imaging probe is embedded in the central aperture, and the specific reference can be made to Figure 1 .

[0032] Wherein, the typical form of imaging probe for medical instruments is line array probe;According to the specific application scene, the frequency is different from 4MHz to 20MHz, and the shallower the applied body surface tissue is, the higher the corresponding frequency is.The frequency of treatment transducer is 200k-10MHz, and the shallower the applied body surface tissue is, the higher the corresponding frequency is.

[0033] In the related art, in the process of focused ultrasound treatment, the treatment area cannot be monitored in real time to avoid other tissues and ensure the accuracy of the treatment area.

[0034] In the embodiment of the utility model, a real-time tissue treatment and monitoring treatment head is integrated with treatment transducer (referred to as treatment transducer) and imaging transducer (referred to as imaging probe) for focused ultrasound treatment, as a diagnosis and treatment integrated element;The section of the tissue measured by the imaging probe contains at least one focused region center (the transducer is referred to as main transducer) of the treatment transducer.

[0035] Through the embodiment of the utility model, the integrated treatment transducer and imaging probe can monitor in real time while treating the target object, can avoid other tissues and ensure the accuracy of the treatment area;Further, the defect that the focused ultrasound heating treatment area and the monitoring area are out of sync in space position in the prior art is solved.

[0036] In the related art, the heating of focused ultrasound also brings many problems. The treatment effect thereof depends on heating, such as ultrasonic ablation, warm ultrasonic treatment, and the like. Temperature has a decisive influence on the safety, comfort, and effectiveness of treatment; however, in actual application, there is a lack of effective monitoring means for the tissue in treatment. Existing technologies have invasive temperature measurement, such as inserting a thermocouple in the process of cancer tissue ablation, but this brings pain to the patient and the thermocouple affects the heating effect; and nuclear magnetic resonance imaging is used for temperature measurement, but the nuclear magnetic resonance imaging equipment is too expensive, and the temperature measurement is not real-time, so it is difficult to be widely applied.

[0037] A typical focused ultrasound heating product on the market has a single-point heating area (i.e., point-focused ultrasound heating), and there are problems of local temperature being too high and temperature distribution being uneven. The temperature near the focal region is relatively high, and the temperature in the region deviating from the focal region is increased very little, and there is almost no treatment effect. Some alternative solutions are: using a line-focused transducer; or using a transducer with a larger focal region size and poor focusing effect. The above solutions have problems mainly as follows: due to the inherent design and manufacturing non-uniformity of the transducer, and environmental factors, including the blood flow environment and tissue heat dissipation environment in the body (for example, when a small tissue region is heated, if there is a larger blood vessel in the region, the temperature around the blood vessel is increased very little), and external environmental conditions, all of which will make the temperature field distribution no longer uniform, and the designed effect cannot be achieved, but at this time, a single transducer cannot compensate for this part of the deviation. At the same time, the effective heating area of such design is very small, and it takes a long time to treat a piece of tissue, and the user experience is very poor.

[0038] As can be seen, in the conventional thermal therapy mode, there is only a single-point heating heat source, the overall temperature distribution is uneven, and is disturbed by the blood flow environment in the body and external conditions.

[0039] Reference Figure 2 , Figure 2 is a top view schematic diagram of a transducer group of a focused ultrasound heating treatment and monitoring treatment device provided by the present application, comprising an imaging probe 101, a main transducer 1021, and an auxiliary transducer 1022.

[0040] Reference Figure 3 , Figure 3 is a sectional view schematic diagram of a transducer group of a focused ultrasound heating treatment and monitoring treatment device provided by the present application, comprising an imaging probe (equivalent to the imaging probe 101 described above), a main transducer (equivalent to the main transducer 1021 described above), and an auxiliary transducer (equivalent to the auxiliary transducer 1022 described above).

[0041] According to the focused ultrasound heating treatment and monitoring treatment device provided by the present application, the treatment transducer comprises:

[0042] The main transducer 1021 and the at least one auxiliary transducer 1022, wherein the relative position of the main transducer 1021 and the at least one auxiliary transducer 1022 remains unchanged or moves in groups, so that the transducer with the imaging probe remains relatively fixed at the center of the focusing area of the tissue section.

[0043] In the embodiment of the utility model, the treatment transducer can also be a transducer group, that is, the main transducer plus the at least one auxiliary transducer, to realize heating of a larger area.

[0044] In one embodiment, the main transducer and the imaging probe are consistent with the above, but 2-3 annular, linearly focused transducers are added to the outer ring, as shown in Figure 2 Figure 2 An example shows one main transducer and one auxiliary transducer in a ring.

[0045] In the related art, because the treatment head and the imaging probe are separate, repeated positioning is not possible. Especially for the focal area of focused heating, as the center of the highest temperature, the size is also small, and the separate measurement cannot obtain information.

[0046] In the embodiment of the utility model, the auxiliary transducer can also be a plurality of single-point transducers, linearly focused transducers, and combinations thereof around the main transducer. The transducer group (the main transducer plus the at least one auxiliary transducer) should meet the following conditions: the main transducer has a larger maximum heating power; and the auxiliary transducers should be distributed radially symmetrically or uniformly in all directions. Due to the diffusion effect of temperature, the heating center temperature of the main transducer is the highest temperature in the entire temperature field, and the coincidence of the imaging probe and the point ensures the safety of the design.

[0047] Through the embodiment of the utility model, the combination transducer structure of the main transducer plus the at least one auxiliary transducer can realize heating of a larger area, and the main transducer and the imaging probe (the imaging probe) coincide, which can effectively monitor the highest temperature to ensure the safety of the device.

[0048] According to the focused ultrasonic heating treatment and monitoring treatment device provided by the utility model, the main transducer and the at least one auxiliary transducer are single-point focused transducers, linearly focused transducers, or a combination of at least one single-point focused transducer and at least one linearly focused transducer.

[0049] In the embodiment of the utility model, the treatment transducer can be a single-point focused transducer, a linearly focused transducer, or a combination of a plurality of the above transducers, that is, a single main transducer or a combination of the main transducer and a plurality of auxiliary transducers. The relative position can remain unchanged or move in groups; however, the transducer with the imaging probe remains relatively fixed at the center of the focusing area of the imaging probe section.

[0050] ​The embodiment of the utility model discloses can select the specific combination of main transducer and auxiliary transducer according to actual conditions, and the main transducer has greater maximum heating power, and the auxiliary transducer is distributed radially or evenly in all directions.

[0051] According to the focusing ultrasonic heating treatment and monitoring treatment device provided by the utility model, the device further comprises: an external control circuit, which is electrically connected with the treatment transducer and the imaging probe respectively, wherein the external control circuit is used for distinguishing the working time sequence of the treatment transducer and the imaging probe.

[0052] In the embodiment of the utility model, the treatment transducer and the imaging probe are also matched with the external control circuit, which is used for ensuring that the working time sequence of the two is separated, that is, the imaging probe does not work when treatment, and the treatment transducer does not work when measurement, so as to avoid the mutual influence of the two by means of ultrasound, and the parameters obtained by the probe are still coherent and complete, which can reflect the real tissue information.

[0053] In the embodiment of the utility model, through the design of the external control circuit and the combination of the treatment ultrasonic transducer and the imaging probe in the diagnosis and treatment integration, the spatial integration of parts and the time coordination of use process are realized.

[0054] Through the embodiment of the utility model, the working time sequence of the treatment transducer and the imaging probe can be ensured to be separated through the external control circuit, so as to avoid the mutual influence of the two by means of ultrasound.

[0055] According to the focusing ultrasonic heating treatment and monitoring treatment device provided by the utility model, the device further comprises: a mechanical adjusting component, which is connected with the treatment transducer and the imaging probe respectively, and is used for moving the overall position of the treatment transducer and the imaging probe, wherein the overall position movement includes overall depth movement and overall horizontal movement.

[0056] In the embodiment of the utility model, through the mechanical adjusting component, the acting depth of the transducer group is adjusted according to the instruction.

[0057] In some embodiments, the adjusting structure, the transducer group, the control system and the driving system constitute an adjusting control structure.

[0058] For example, by reading the data of the imaging probe for analysis, the temperature of the target tissue is obtained, the difference between the set value and the actual value is calculated by using the control system, so as to adjust the output power of the treatment transducer of the driving system, or / and the acting position of the treatment transducer is adjusted by using the mechanical adjusting component, so as to achieve the effect of adjustment and control.

[0059] Typical action position adjustment is local depth adjustment and overall two-dimensional movement adjustment, that is, each transducer is adjusted by one or more independently controlled Z-direction (i.e., the direction perpendicular to the skin surface on which the action is performed) drive motor or other mechanical structure to change the depth at which the focused area acts on the skin, and the entire treatment head is guided to move on the skin surface as a whole by means of artificial / mechanical arm / auxiliary line / camera, etc.

[0060] It is necessary to adjust the depth of the treatment area in different cases, for example, in fat reduction treatment, if the fat layer of the patient is thick, the depth of the treatment may need to be appropriately increased to ensure that the fat tissue in a larger area is heated. At this time, the Z-direction depth of the transducer can be adjusted to achieve it. In order to achieve more flexible control, the adjustable parameters are: the action depth of each treatment transducer; the output power of each treatment transducer. Based on the above parameter feedback adjustment.

[0061] Through the embodiments of the utility model, the treatment ultrasonic transducer can be used as a plurality of groups, and the mechanical adjusting part can be dynamically feedback adjusted based on the information of the imaging probe, the adjusting parameters are the action depth of the transducer and / or the power of the transducer, and flexible adjustment of the treatment transducer and the imaging probe is realized.

[0062] According to the focused ultrasonic heating treatment and monitoring treatment device provided by the utility model, the device further comprises: a hardware component, the hardware component comprises a circuit connection and data transmission module, and is electrically connected with the imaging probe, and the hardware component is used for dividing the image data returned by the imaging probe into two groups of data,

[0063] According to the focused ultrasonic heating treatment and monitoring treatment device provided by the utility model, the two groups of data are respectively used for converting into image data and ultrasonic radio frequency signals.

[0064] In the embodiments of the utility model, the imaging probe is divided into the same two groups of data through the hardware component, one group of data is output as image data after being processed by the hardware component, and the other group of data is an ultrasonic radio frequency (RF, Radio Frequency) signal or an in-phase quadrature (IQ, In-phase Quadrature) signal processed by beam synthesis. The signal is subjected to subsequent processing on the host computer, such as obtaining the temperature, elasticity and acoustic attenuation of the target tissue. The B-ultrasound image is displayed in real time through the display, and the temperature information of the tissue can be superimposed on the B-ultrasound image.

[0065] It should be noted that the traditional B-ultrasound data processing flow is as follows: after the multi-element probe collects data, the data is subjected to beam synthesis, and the original RF signal is obtained; next, the I / Q signal is obtained through quadrature demodulation; then, the image data is obtained through processes such as filtering, gain adjustment, attenuation correction, time domain frequency domain conversion, etc.

[0066] In the embodiment of the utility model, data adds a signal interface at RF signal or I / Q signal, can be USB3.0 or PCIE interface considering data volume, its feature is transmission data speed > 1 G bite / s, this data can obtain the temperature information of target tissue through further data processing, such as thermal strain imaging method temperature measurement, attenuation coefficient method temperature measurement etc.;Obtain the elastic modulus information of tissue by using elastic ultrasonic imaging.

[0067] Through the embodiment of the utility model, the hardware components are respectively electrically connected with the treatment transducer and the imaging probe, so that the treatment data and the monitoring data can be acquired and visually displayed.

[0068] According to the focused ultrasound heating treatment and monitoring treatment device provided by the utility model, the device further comprises: a host computer, the host computer is electrically connected with the hardware components, and is used for processing ultrasonic radio frequency signals to obtain target information of a tissue section, wherein the target information includes temperature, elasticity and acoustic attenuation.

[0069] In the embodiment of the utility model, based on the imaging probe, the hardware components and the host computer, an ultrasonic image-based tissue information acquisition device is formed, the imaging probe is divided into the same two groups of data through the hardware components, one group of data is output as image data after being processed by the hardware components;The other group of data is ultrasonic radio frequency signals or in-phase quadrature signal signals processed by beam synthesis. The signals are processed subsequently in the host computer, such as obtaining temperature, elasticity and acoustic attenuation information of target tissue. The B-ultrasound image is displayed in real time through the display, and the temperature information of the tissue can be superimposed on the B-ultrasound image.

[0070] For the imaging probe, if data is collected according to a fixed frame rate, for example, 20fps, that is, ultrasonic image data is collected once every T=0.05s. The time T1 includes the imaging probe duration T1 and the waiting time T'. The duration T1 includes: device response time T1a;Ultrasonic emission time T1b;Transmission-reception interval T1c;Ultrasonic receiving time T1d;Waiting time T'.

[0071] The acquisition of ultrasonic information of human tissue structure is through the pulse echo amplitude method, in which method, the actual travel of ultrasonic wave is 2 times of the detection depth (s), that is, 2s. At present, it is generally recognized that the average speed of human soft tissue is 1540m / s. Therefore, the detection of the corresponding detection depth is also called the transit time t, which is t=2s / c, and the detection depth per centimeter is about 13us.

[0072] In the current application design, the probe depth is generally no more than 10 cm, so the ultrasound emission time is equal to the ultrasound receiving time, which is about 0.13 ms. The device response time is in several microseconds (negligible); the emission-receiving interval is usually about 1 ms; the total working time is no more than 2 ms. Considering improving the repetition frequency to improve image quality, the total working time is also no more than 10 ms in the case of repeating 4-5 times. Therefore, at 20 fps, the waiting time is greater than 40 ms; at 40 fps, the waiting time is greater than 15 ms.

[0073] Reference Figure 4 , Figure 4 is the structure diagram of interval time and duration provided by the utility model, including treatment transducer duration T3, interval time T2, image probe duration T1 and interval time T4.

[0074] In order to ensure the continuous acquisition of the imaging probe, the strict sense of continuous signal acquisition can be realized in the form of Figure 4 .

[0075] In the embodiment of the utility model, interval time T2 and T4 are added to ensure that the treatment transducer and the image probe do not interfere with each other, and 1 ms can be taken; the image probe duration T1 is as described above, T'=T2+T3+T4. Therefore, it can be seen that the treatment transducer is controlled to heat in the waiting time in each cycle T of the image probe, so that the continuous acquisition of the image probe in the working process of the treatment transducer can be realized, and the two do not interfere with each other. Obviously, with the increase of the sampling frame number, the time of T' will be reduced. Define the highest duty cycle of the treatment transducer σ=T3 / T, for example, at 20 fps, σ=76%; at 40 fps, σ=52%. Too low sampling frame number will lead to poor continuity, increase the cumulative error of the obtained information, and reduce the signal quality; increasing the sampling frame number will reduce σ, thereby reducing the average heating power of the heating transducer, leading to slow temperature rise or difficulty in maintaining the heating temperature. According to industry experience, the frame rate of 50 fps is achievable for image devices, at this time σ=40%, that is, the power upper limit value of the treatment transducer design needs to be permanently changed to 2.5 times the normal value, and increasing further will greatly burden the driving circuit of the image probe and the treatment transducer, but the reduction of the step is very limited, so the benefit is very low; the normal water level of the current image probe can realize a frame rate of more than 10 fps, and when reduced to 10 fps, σ=88%, the step is long but acceptable, and further reduction cannot bring obvious cost reduction to the driving circuit of the image probe and the treatment transducer. Therefore, 10-50 fps is the preferred working range of the image probe.

[0076] The device further comprises: a plurality of temperature sensors, wherein the plurality of temperature sensors are attached to the heating area of the treatment transducer, and are used for detecting the real-time temperature of the heating area of the treatment transducer.

[0077] At present, the traditional image probe, such as B-ultrasound, can only obtain the image of the tissue, but cannot provide the information of the tissue change and temperature change caused by the focused ultrasonic heating. The tissue data collected by the image probe can be used for processing more contents, including real-time measurement of the temperature of the treatment area, so as to ensure the safety, comfort and effectiveness of the treatment. In addition to the temperature information, other processing based on the ultrasonic image, such as tissue feature identification and blood flow detection, also has high application value.

[0078] Therefore, in the prior art, the tissue temperature rise cannot be non-invasively and real-timely measured and monitored during the focused ultrasonic treatment, and the safety, comfort and effectiveness are problems.

[0079] In the embodiment of the utility model, the imaging probe, the main transducer, the plurality of auxiliary transducers and the plurality of temperature sensors located on the surface of the attached area can constitute a coordinated ultrasonic heating system of multi-point area heating.

[0080] According to the focused ultrasonic heating treatment and monitoring treatment device provided by the utility model, the imaging probe is embedded in the center position of the treatment transducer.

[0081] In the embodiment of the utility model, when the treatment transducer is a combined transducer, the imaging probe is embedded in the center position of the main transducer, and the auxiliary transducer can also be a plurality of single-point transducers, a line-focused transducer and a combination thereof surrounding the main transducer. The transducer group (the main transducer plus at least one auxiliary transducer) should meet the following conditions: the main transducer has a larger maximum heating power; and the auxiliary transducers should be radially symmetrically distributed or uniformly distributed in all directions. Due to the diffusion effect of temperature, the heating center temperature of the main transducer is the highest temperature in the entire temperature field, and the coincidence of the imaging probe and the point ensures the safety of the design.

[0082] In the embodiment of the utility model, the working frequency, form and driving signal of each transducer can be independently controlled. According to the temperature signal obtained by the imaging probe and the signals of the plurality of temperature sensors on the surface of the attached area, the output of each transducer is adjusted, so as to maintain the stability of the temperature field in the larger heating area.

[0083] In the embodiment of the utility model, the coordinated ultrasonic heating system of multi-point area heating has higher adjustment freedom, and the whole system works according to the time sequence set in the above embodiment, therefore, in order to facilitate design and control, all the transducers are preferably fixed to the duty ratio of sigma, and the switch is opened and closed, and the heating power of the transducer is controlled by changing the driving voltage amplitude (by fixing the driving voltage amplitude, the duty ratio can also be adjusted, but the duty ratio is not greater than sigma).

[0084] Reference Figure 5 , Figure 5 The signal feedback adjustment logic diagram provided by the utility model. The coordinated ultrasonic heating system of multi-point area heating works through signal feedback adjustment control, and the adjustment logic is as shown in the figure, the imaging module measures the center temperature of the main transducer, and obtains the total heating power of all treatment transducers through PID control, and distributes the heating power of the auxiliary transducer; when there is difference in the plurality of temperature sensors on the surface, temperature calibration is carried out and the center temperature of the main transducer measured by the imaging module is returned, and the distribution of the heating power of the auxiliary transducer is stopped.

[0085] Compared with the heating mode of single-point focusing, the heating center of the design is located at multiple points in the heating area, and the temperature of the whole area is increased to the set value together with the heating process. As described above, the non-uniformity of the transducer inherent design and manufacture, and environmental factors, including the blood flow environment and tissue heat dissipation environment in the body, and external environmental conditions, will make the temperature field distribution no longer uniform; through the plurality of temperature sensors at different positions on the surface of the heating area, the difference can be obtained. The temperature value has difference with the temperature in the tissue, but the temperature change rule is sufficient to reflect the temperature change rule in the corresponding tissue. Therefore, according to the center temperature of the main transducer measured by the imaging probe, the total power of all transducers required for heating (to maintain the temperature rise and temperature maintenance of the whole area) can be obtained through PID control.

[0086] Further, according to the temperature change of each temperature sensor, the power of each transducer is distributed in real time, and the purpose is to balance the temperature, and the power distribution of the transducer is reduced for the area with faster temperature rise. A typical and mature way is to use PID (Proportional-Integral-Derivative) neuron network decoupling control algorithm.

[0087] At the same time in the process, because of the temperature measurement principle of the imaging module itself, cumulative error is easy to appear in long-term temperature measurement and result deviation, the temperature sensor on the skin provides anchor value reference, and the temperature measurement result can be corrected.

[0088] The utility model provides a kind of diagnosis and treatment integrated treatment ultrasonic transducer and imaging probe combination design, including the integration of space and the time coordination of use process is proposed in the above embodiment of the utility model.The treatment ultrasonic transducer can be used as multiple groups, based on the information of imaging probe carries out dynamic feedback adjustment, and the adjustment parameter is transducer action depth and / or transducer power.By imaging probe, the B ultrasonic image of tissue and other tissue information, such as temperature / elasticity etc.

[0089] The device embodiments described above are only schematic, wherein the units described as separate components can or can not be physically separate, and the components displayed as units can or can not be physical units, i.e., can be located in one place, or can be distributed on a plurality of network units. Part or all of the modules can be selected according to actual needs to achieve the purpose of the embodiment scheme. Those skilled in the art can understand and implement without creative labor.

[0090] From the description of the above embodiments, those skilled in the art can clearly understand that the embodiments can be realized by software and necessary general hardware platform, and of course, can also be realized by hardware. Based on such understanding, the above technical solutions can be embodied in the form of software product, which can be stored in computer readable storage medium, such as ROM / RAM, magnetic disk, optical disk, etc., including a plurality of instructions to make a computer device (which can be personal computer, server, or network device, etc.) execute the method described in each embodiment or some part of the embodiment.

[0091] Finally, it should be pointed out that: the above embodiments are only used to illustrate the technical solutions of the utility model, but not to limit them; although the utility model has been described in detail with reference to the foregoing embodiments, those skilled in the art should understand that they can still modify the technical solutions recorded in the foregoing embodiments, or make equivalent replacement for some technical features; and these modifications or replacements do not make the essence of the corresponding technical solutions deviate from the spirit and scope of the technical solutions of the embodiments of the utility model.

Claims

1. A focused ultrasound heating treatment and monitoring apparatus, characterized by, The device comprises: a therapy transducer and an imaging probe, wherein the therapy transducer and the imaging probe are integrated; wherein the therapy transducer is used for focused ultrasound therapy, and the imaging probe is used for detecting regional imaging; a tissue section obtained by the imaging probe detection includes at least one focused region center of the therapy transducer.

2. The focused ultrasound heating treatment and monitoring apparatus according to claim 1, wherein, The therapy transducer comprises: a main transducer and at least one auxiliary transducer, wherein the relative position of the main transducer and the at least one auxiliary transducer remains unchanged or moves in groups, so that the focused region center is relatively fixed on the tissue section transducer and the imaging probe.

3. The focused ultrasound heating treatment and monitoring apparatus of claim 2, wherein, The main transducer and the at least one auxiliary transducer are single-point focusing transducers, line focusing transducers, or a combination of the at least one single-point focusing transducer and the at least one line focusing transducer.

4. The focused ultrasound heating treatment and monitoring apparatus of claim 1, wherein, The device further comprises: an external control circuit, which is electrically connected to the therapy transducer and the imaging probe respectively, wherein the external control circuit is used to distinguish the working time sequence of the therapy transducer and the imaging probe.

5. The focused ultrasound heating treatment and monitoring apparatus of claim 1, wherein, The device further comprises: a mechanical adjustment component, which is connected to the therapy transducer and the imaging probe respectively, and is used for overall position movement of the therapy transducer and the imaging probe, wherein the overall position movement includes overall depth movement and overall horizontal movement.

6. The focused ultrasound heating treatment and monitoring apparatus of claim 1, wherein, The device further comprises: a hardware component, which comprises a circuit connection and data transmission module, and is electrically connected to the imaging probe, wherein the hardware component is used to divide the image data returned by the imaging probe into two groups of data.

7. The focused ultrasound heating treatment and monitoring apparatus of claim 6, wherein, The two groups of data are respectively used to convert into image data and ultrasonic radio frequency signals.

8. The focused ultrasound heating treatment and monitoring apparatus of claim 7, wherein, The device further comprises: a host computer, which is electrically connected to the hardware component, and is used to process the ultrasonic radio frequency signals to obtain target information of the tissue section, wherein the target information includes temperature, elasticity, and acoustic attenuation.

9. The focused ultrasound heating treatment and monitoring apparatus of claim 1, wherein, The device further comprises: a plurality of temperature sensors, wherein the plurality of temperature sensors are attached to the heating region of the therapy transducer, and are used to detect the real-time temperature of the heating region of the therapy transducer.

10. The focused ultrasound heating treatment and monitoring apparatus of claim 1, wherein, The imaging probe is embedded in the center position of the therapy transducer.

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