Jig for absorbing liquid in biological experiment

By designing an array of aspiration needles and a threaded connection for biological experiments, the problem of low efficiency in traditional dropper aspiration was solved, achieving efficient and accurate batch aspiration and ensuring the stability and safety of the experiment.

CN223732805UActive Publication Date: 2025-12-30INST OF MICROBIOLOGY CHINESE ACAD OF SCI
View PDF 0 Cites 0 Cited by

Patent Information

Application Number
CN202520119833.3
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2025-01-17
Publication Date
2025-12-30
Estimated Expiration
2035-01-17

AI Technical Summary

Technical Problem

Traditional dropper aspiration methods are inefficient in biological experiments, making it difficult to meet the needs of high-throughput screening and large-scale cell culture media. Furthermore, they are subject to operational complexity and the risk of human error, which affects the accuracy and reliability of experimental results.

Method used

A fixture for aspirating liquid in biological experiments is used, including a mounting base and an array of aspiration needles. The end of the aspiration needle away from the mounting base is provided with an aspiration groove, and the groove wall is provided with a frosted or serrated texture layer. The aspiration needle and the mounting base are detachably connected by a threaded engagement.

Benefits of technology

It improves the efficiency of batch liquid aspiration, reduces the number of operations and experimental time, reduces human error, ensures the accuracy and stability of experimental data, and improves experimental efficiency and safety.

✦ Generated by Eureka AI based on patent content.

Smart Images

  • Figure CN223732805U_ABST
    Figure CN223732805U_ABST
Patent Text Reader

Abstract

The utility model discloses a jig for absorbing liquid in a biological experiment. The jig for biological experiment liquid suction comprises a mounting base, a plurality of liquid suction needles are distributed on the mounting base in an array mode, a liquid suction groove is formed in the end, away from the mounting base, of each liquid suction needle, and a frosted line layer or a sawtooth line layer is arranged on the groove wall of each liquid suction groove. According to the utility model, a plurality of liquid suction needles are distributed on the mounting seat in an array form, so that a plurality of samples or reagents can be sucked and transferred at the same time in single operation, and the batch liquid suction efficiency is improved; besides, the liquid suction groove is formed in the end, far away from the mounting seat, of the liquid suction needle, so that the liquid suction area is increased, the liquid can be more sufficiently and uniformly distributed at the needle tip, the liquid suction path is optimized, and the dripping leakage phenomenon is reduced; in addition, the frosted line layer or the sawtooth line layer is arranged on the groove wall of the liquid suction groove, the adhesive force between the liquid and the groove wall is enhanced, and the liquid is effectively prevented from sliding off in the suction and transfer process.
Need to check novelty before this filing date? Find Prior Art

Description

Technical Field

[0001] This utility model relates to the field of liquid aspiration fixtures, and in particular to a fixture for liquid aspiration in biological experiments. Background Technology

[0002] In the field of biological experiments, the precise aspiration and transfer of liquids is one of the key steps in the experimental process, directly affecting the accuracy and reproducibility of experimental results. Traditionally, this operation mainly relies on droppers, which are widely used due to their simple structure and convenient operation. However, with the continuous advancement of biological experimental technology and the increasing scale of experiments, especially when processing large numbers of samples or conducting high-throughput screening experiments, the dropper method has gradually revealed its inefficiency.

[0003] Specifically, droppers can only aspirate and transfer a limited amount of liquid at a time. When faced with scenarios involving large-scale liquid aspiration, such as changing large-scale cell culture media or simultaneously dispensing multiple sets of biochemical reagents, operators must repeat the aspiration-transfer action multiple times. This not only significantly increases the complexity of experimental procedures but may also lead to a substantial extension of experimental time, thus affecting experimental efficiency and the workload of researchers. Furthermore, frequent manual operations can introduce human error, affecting the accuracy of experimental data.

[0004] Given the aforementioned limitations, the industry urgently needs a tool that can efficiently and accurately complete batch liquid aspiration tasks to meet the high demands of efficiency and precision in modern biological experiments. Utility Model Content

[0005] The purpose of this invention is to overcome the shortcomings of the prior art and provide a fixture for aspirating liquids in biological experiments.

[0006] To solve the above-mentioned technical problems, the present invention adopts the following technical solution:

[0007] This utility model provides a fixture for liquid aspiration in biological experiments, comprising: a mounting base, on which a plurality of aspiration needles are arranged in an array, and an aspiration groove is provided at the end of each aspiration needle away from the mounting base, the groove wall being provided with a frosted texture layer or a serrated texture layer.

[0008] In one specific embodiment, the mounting base is provided with a threaded through hole, and the end of the suction needle away from the suction groove is provided with a threaded end. The threaded end cooperates with the threaded through hole so that the suction needle and the mounting base form a detachable connection.

[0009] In one specific embodiment, the length of the threaded end is slightly less than the length of the threaded through hole.

[0010] In one specific embodiment, the aspiration needle is cylindrical.

[0011] In one specific embodiment, the diameter of the aspiration needle is 0.8mm-2.5mm.

[0012] In one specific embodiment, the width of the liquid suction groove is 0.4mm-1.2mm.

[0013] In one specific embodiment, the distance between adjacent aspiration needles is 8mm-15mm.

[0014] In one specific embodiment, the mounting base is further provided with a handle on the side away from the liquid suction tank.

[0015] In one specific embodiment, the mounting base is square in shape.

[0016] In one specific embodiment, the aspiration needle is made of metal.

[0017] The present invention provides a fixture for liquid aspiration in biological experiments, which offers several advantages over existing technologies. Firstly, the array of aspiration needles on the mounting base allows for the simultaneous aspiration and transfer of multiple samples or reagents in a single operation, significantly improving the efficiency of batch liquid aspiration. Secondly, the presence of an aspiration groove at the end of the aspiration needle furthest from the mounting base not only increases the aspiration area, enabling more thorough and even distribution of liquid at the needle tip, but also optimizes the liquid aspiration path through the specific shape of the groove, reducing dripping. Thirdly, the groove wall is textured with a frosted or serrated surface, enhancing adhesion between the liquid and the groove wall and effectively preventing liquid slippage during aspiration and transfer. This further improves the stability and accuracy of liquid aspiration, ensuring the reliability of experimental data.

[0018] The present invention will be further described below with reference to the accompanying drawings and specific embodiments. Attached Figure Description

[0019] To more clearly illustrate the technical solutions in the embodiments of this utility model, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of this utility model. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0020] Figure 1 A front view of the fixture for aspirating liquids in biological experiments provided by this utility model;

[0021] Figure 2 This is a schematic diagram of the back structure of the fixture for aspirating liquid in biological experiments provided by this utility model. Detailed Implementation

[0022] To make the objectives, technical solutions, and advantages of this utility model clearer, the present utility model will be further described in detail below with reference to the accompanying drawings and specific embodiments.

[0023] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those skilled in the art without creative effort are within the protection scope of the present utility model.

[0024] In the description of this utility model, it should be understood that the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", etc., indicating the orientation or positional relationship are based on the orientation or positional relationship shown in the accompanying drawings, and are only for the convenience of describing this utility model and simplifying the description, and are not intended to indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of this utility model.

[0025] Furthermore, the terms "first" and "second" are used for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of that feature. In the description of this utility model, "a plurality of" means two or more, unless otherwise explicitly specified.

[0026] In this utility model, unless otherwise explicitly specified and limited, the terms "installation," "connection," "joining," and "fixing," etc., should be interpreted broadly. For example, they can refer to a connection, a detachable connection, or an integral part; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; they can refer to the internal communication of two components or the interaction between two components. Those skilled in the art can understand the specific meaning of the above terms in this utility model according to the specific circumstances.

[0027] In this invention, unless otherwise explicitly specified and limited, "above" or "below" the second feature can include direct contact between the first and second features, or contact between the first and second features through another feature between them. Furthermore, "above," "over," and "on top" of the second feature includes the first feature directly above or diagonally above the second feature, or simply indicates that the first feature is at a higher horizontal level than the second feature. "Below," "below," and "under" the second feature includes the first feature directly below or diagonally below the second feature, or simply indicates that the first feature is at a lower horizontal level than the second feature.

[0028] In the description of this specification, the references to terms such as "one embodiment," "some embodiments," "example," "specific example," or "some examples," etc., indicate that a specific feature, structure, material, or characteristic described in connection with that embodiment or example is included in at least one embodiment or example of the present invention. The illustrative expressions of the above terms in this specification should not be construed as necessarily referring to the same embodiment or example. Furthermore, the specific features, structures, materials, or characteristics described may be combined in any suitable manner in one or more embodiments or examples. In addition, those skilled in the art can combine and integrate the different embodiments or examples described in this specification.

[0029] See Figures 1 to 2 The specific embodiment shown in this utility model discloses a fixture for liquid aspiration in biological experiments, including: a mounting base 10, on which a plurality of aspiration needles 20 are arranged in an array, and a liquid aspiration groove 21 is provided at one end of the aspiration needles 20 away from the mounting base 10, and the groove wall of the liquid aspiration groove 21 is provided with a frosted texture layer or a serrated texture layer.

[0030] Specifically, the mounting base 10 on the fixture has several aspiration needles 20 arranged in an array. This design allows for the simultaneous aspiration and transfer of multiple samples or reagents in a single operation, greatly improving the efficiency of batch aspiration. Compared to traditional dropper aspiration, it significantly reduces the number of operations and experimental time, making it particularly suitable for high-throughput screening experiments or large-scale cell culture scenarios that require processing large numbers of samples. Furthermore, an aspiration groove 21 is provided at the end of the aspiration needle 20 furthest from the mounting base 10. This design not only increases the aspiration area, allowing the liquid to be distributed more fully and evenly at the needle tip, but also optimizes the liquid aspiration path through the specific shape of the aspiration groove 21, reducing dripping. In addition, the walls of the aspiration groove 21 are textured with a frosted or serrated surface treatment. This surface treatment enhances the adhesion between the liquid and the groove wall, effectively preventing liquid slippage during aspiration and transfer, further improving the stability and accuracy of aspiration, and ensuring the reliability of experimental data.

[0031] More specifically, the number and array distribution of the aspiration needles 20 can be flexibly adjusted according to specific experimental needs, improving the applicability and flexibility of the fixture.

[0032] In one embodiment, the mounting base 10 is provided with a threaded through hole, and the end of the suction needle 20 away from the suction groove 21 is provided with a threaded end. The threaded end cooperates with the threaded through hole so that the suction needle 20 and the mounting base 10 form a detachable connection.

[0033] Specifically, the threaded connection design creates a secure, detachable connection between the aspiration needle 20 and the mounting base 10, effectively preventing the aspiration needle 20 from loosening or falling off during the experiment, ensuring the accuracy and safety of the experiment. Furthermore, the threaded connection allows the aspiration needle 20 to be easily removed from the mounting base 10, facilitating cleaning, disinfection, or replacement of the aspiration needle 20 as needed, thus improving the flexibility and applicability of the fixture. The quick-release design between the aspiration needle 20 and the mounting base 10 significantly shortens the preparation and completion time of the experiment, improving experimental efficiency. Simultaneously, the secure connection reduces experimental interruptions caused by the loosening of the aspiration needle 20, further enhancing experimental efficiency. Additionally, the threaded design simplifies and facilitates cleaning and maintenance of the fixture, allowing researchers to easily disassemble the aspiration needle 20 for cleaning and disinfection, ensuring the hygiene and safety of the fixture.

[0034] In one embodiment, the length of the threaded end is slightly less than the length of the threaded through hole.

[0035] Specifically, based on the size of the threaded end of the suction needle 20 and the required depth of fit, the length of the threaded through hole is reasonably set to ensure that after the suction needle 20 is installed, the threaded end can be fully screwed into the threaded through hole without protruding from its surface. In other words, by ensuring that the threaded end does not protrude from the threaded through hole, the risk of accidental contact or improper operation by the experimenter is avoided, significantly improving the safety of the fixture. This design detail reflects meticulous consideration for the safety of experimenters, enhances their trust and confidence in the fixture, helps improve their focus and accuracy during experiments, avoids experimental interruptions caused by scratches or other accidents, ensures the continuity of experiments and the integrity of data, and improves experimental efficiency. This not only enhances the practicality of the fixture but also reflects a focus on user experience, improving the overall quality and market competitiveness of the fixture.

[0036] In one embodiment, the aspiration needle 20 is cylindrical.

[0037] Specifically, the cylindrical aspiration needle 20 has a smooth outer surface and a consistent diameter, which helps reduce resistance when aspirating and transferring liquids, allowing the liquid to be aspirated more smoothly and quickly. In addition, the cylindrical aspiration needle 20 has no complex structure or hard-to-reach corners, making cleaning and maintenance simpler and more convenient, helping to maintain the hygiene and performance of the fixture.

[0038] In one embodiment, the diameter of the aspiration needle 20 is 0.8 mm to 2.5 mm.

[0039] Specifically, the appropriate diameter of the aspirator 20 is selected based on the specific type and requirements of the biological experiment. For example, a smaller diameter aspirator 20 can be selected for experiments requiring precise aspiration of minute amounts of liquid, while a larger diameter aspirator 20 can be selected for experiments requiring rapid aspiration of large amounts of liquid. Furthermore, by precisely controlling the diameter of the aspirator 20, the amount of liquid aspirated can be precisely controlled, improving the accuracy and repeatability of the experiment. Additionally, aspirator 20s of different diameters can meet the aspiration flow rate requirements of different experiments, ensuring rapid and stable aspiration of liquid during the experiment. Moreover, the availability of aspirator 20s with multiple diameter options allows the fixture to be applied to more types of biological experiments, improving its flexibility and versatility. Finally, precise diameter control of the aspirator 20 helps reduce errors during the experiment, improving the reliability and accuracy of experimental data.

[0040] In one embodiment, the width of the liquid suction groove 21 is 0.4mm-1.2mm.

[0041] Specifically, different widths of the aspiration groove 21 can be flexibly selected according to experimental needs. For example, for experiments requiring precise aspiration of trace amounts of liquid, a narrower aspiration groove 21 can be selected; while for experiments requiring rapid aspiration of larger amounts of liquid, a wider aspiration groove 21 can be selected. Furthermore, precise width control of the aspiration groove 21 helps reduce liquid leakage and waste during the experiment, improving the accuracy and precision of liquid aspiration. Additionally, different widths of the aspiration groove 21 can adapt to different liquid flow rates, ensuring stable and uniform liquid aspiration during the experiment. Moreover, providing a variety of aspiration groove 21 width options allows the fixture to be applicable to more types of biological experiments, improving its flexibility and versatility. Furthermore, the precise width and edge treatment of the aspiration groove 21 help reduce errors during the experiment, improving the reliability and accuracy of experimental data.

[0042] In one embodiment, the distance between adjacent aspiration needles 20 is 8mm-15mm.

[0043] Specifically, the distance between adjacent aspiration needles 20 can be flexibly adjusted according to the specific needs of the experiment. For example, for experiments requiring simultaneous aspiration of liquid from multiple different locations, a smaller distance can be selected to improve aspiration efficiency; while for experiments requiring avoidance of cross-contamination, a larger distance can be selected to ensure safety. Furthermore, a reasonable spacing between the aspiration needles 20 ensures that each needle can work independently and efficiently, improving the speed and efficiency of liquid aspiration. It also avoids mutual interference caused by needles 20 being too close together, such as cross-contamination or uneven aspiration, thus improving the accuracy and reliability of the experiment. In addition, the availability of multiple spacing options for the aspiration needles 20 allows the fixture to be applied to more types of biological experiments, improving its flexibility and versatility.

[0044] In one embodiment, the mounting base 10 is further provided with a handle portion 30 on the side away from the liquid suction groove 21.

[0045] Specifically, the handle 30 is designed to be integrated with or detachably connected to the mounting base 10 to ensure its stability and durability during use. The handle 30 may feature an anti-slip design, such as added texture or a rubber coating, to improve grip stability and safety. The handle 30 is mounted on the side of the mounting base 10 away from the aspiration tank 21; this design ensures that the operator will not interfere with the working areas of the aspiration needle 20 and the aspiration tank 21 during operation.

[0046] More specifically, the addition of the handle 30 makes it easier and faster for experimenters to operate the fixture, improving experimental efficiency. In addition, the non-slip design of the handle 30 improves grip stability and reduces the risk of experimental accidents caused by unstable grip. Furthermore, the design of the handle 30 takes into account ease of cleaning and maintenance, helping to keep the fixture clean and hygienic.

[0047] In one embodiment, the mounting base 10 is square in shape.

[0048] Specifically, the square-shaped mounting base 10 has a stable support structure, ensuring that the fixture remains stable during placement and is not easily tipped over or rolled, thus improving safety during experiments. Furthermore, the square shape allows the mounting base 10 to make full use of space, reducing unnecessary gaps and improving the overall compactness and portability of the fixture.

[0049] In one embodiment, the aspiration needle 20 is made of metal.

[0050] Specifically, the aspiration needle 20 is made of metals such as stainless steel, titanium alloy, or high-quality alloy steel, which are widely used due to their high strength, good corrosion resistance, and machinability. Stainless steel is one of the commonly used materials for manufacturing the aspiration needle 20 because of its excellent corrosion resistance, strength, and ease of cleaning. Titanium alloy is also considered in some special applications due to its lightweight, high strength, and good biocompatibility.

[0051] More specifically, the metal aspiration needle 20 has sufficient strength to withstand various mechanical stresses and pressures during the experiment, ensuring the stability and reliability of the aspiration process. Furthermore, the aspiration needle 20, made of stainless steel or titanium alloy, has excellent corrosion resistance, enabling it to withstand various corrosive substances that may be encountered during the experiment, thus extending its service life.

[0052] The above embodiments are preferred implementations of this utility model. In addition, this utility model can also be implemented in other ways. Any obvious substitutions without departing from the concept of this technical solution are within the protection scope of this utility model.

Claims

1. A jig for use in biological experiments, comprising: The application relates to a liquid suction device, which comprises: a mounting base, wherein a plurality of liquid suction needles are arranged on the mounting base, and a liquid suction groove is arranged at one end of each liquid suction needle away from the mounting base, and a frosted layer or a sawtooth layer is arranged on the groove wall of the liquid suction groove.

2. The tool for biological experiment pipetting according to claim 1, wherein, The mounting base is provided with a threaded through hole, and the end of each liquid suction needle away from the liquid suction groove is provided with a threaded end, which is matched with the threaded through hole, so that the liquid suction needle and the mounting base are detachably connected.

3. The tool for biological experiment pipetting according to claim 2, wherein, The length of the threaded end is slightly lower than the length of the threaded through hole.

4. The tool for biological experiment pipetting according to claim 1, wherein, The liquid suction needle is in a cylindrical shape.

5. The tool for biological experiment pipetting according to claim 4, wherein, The diameter of the liquid suction needle is 0.8-2.5 mm.

6. The tool for biological experiment pipetting according to claim 5, wherein, The width of the liquid suction groove is 0.4-1.2 mm.

7. The tool for biological experiment pipetting according to claim 1, wherein, The distance between adjacent liquid suction needles is 8-15 mm.

8. The tool for biological experiment pipetting according to claim 1, wherein, The side of the mounting base away from the liquid suction groove is further provided with a handle part.

9. The tool for biological experiment pipetting according to claim 1, wherein, The mounting base is in a square shape.

10. The tool for biological experiment pipetting according to claim 1, wherein, The liquid suction needle is made of metal.