Rat fixing device
By designing a rat restraint device, which uses a first fixation plate and a second fixation plate to fix the rat's head and chest/abdomen, the problem of high physical exertion and manpower requirements for rat blood collection operators in existing technologies is solved. This enables rapid and stable rat restraint by a single person, thus improving blood collection efficiency.
Patent Information
- Application Number
- CN202422904171.9
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-11-27
- Publication Date
- 2026-01-02
- Estimated Expiration
- 2034-11-27
AI Technical Summary
In the existing technology, the operation of collecting blood from the anterior vena cava of rats requires two people to assist in fixation, which leads to high physical exertion for the operators and makes it easy for blood collection to be unstable due to errors, and requires a lot of human resources.
A rat restraint device was designed, including a first fixation plate and a second fixation plate. The rat's head is fixed by a first fixation strap, and the chest or abdomen is fixed by a second fixation strap. Combined with a pole and a stable platform, the rat can be quickly and stably restrained by a single person.
It reduces the physical exertion of the operator in restraining the rat, reduces the manpower required for auxiliary fixation, and improves the stability and efficiency of blood collection.
Smart Images
Figure CN223746497U_ABST
Abstract
Description
TECHNICAL FIELD
[0001] The utility model relates to rat anterior vena cava blood sampling technical field, especially a rat restraint device. BACKGROUND
[0002] Rat blood collection is widely used in pharmacokinetics and toxicokinetics research. According to the requirements of the International Conference on Harmonization of Technical Requirements for Registration of Pharmaceuticals for Human Use (ICH) guidelines and the National Medical Products Administration (NMPA) guidelines, the number of blood sampling time points in rat toxicokinetics research needs to meet the requirements of dynamic drug exposure evaluation.
[0003] Rat anterior vena cava blood sampling is a commonly used blood sampling method that meets the research needs. Adult rats used for blood sampling generally weigh 250g-600g, and in pharmacokinetics and toxicokinetics research, a rat often needs to be repeatedly sampled more than 10 times in one round of blood sampling, and multiple rounds of blood sampling are generally required in a long-term test. Therefore, the operator needs to fix the rat a large number of times.
[0004] Currently, the artificial restraint method for rat anterior vena cava blood sampling is two-person restraint. One hand of the operator holds the rat's neck and back skin to keep the rat's head, neck, and chest vertical, exposing the neck injection site. The other assistant fixes the front limb of the injection site to keep it horizontal. The operator's other hand keeps the syringe parallel to the rat's head and tilts it outward by 5°-10°, tilting the needle tip toward the ventral side. The needle is inserted for blood sampling, and after blood sampling, the blood is immediately transferred to an EP tube. The operator presses the blood sampling site to stop bleeding.
[0005] A large number of restraint operations can easily cause the operator to be physically exhausted, leading to unstable rat restraint, and blood collection failure due to operation errors. In addition, the operator needs to be assisted by an assistant while performing artificial restraint, resulting in labor consumption. UTILITY MODEL CONTENT
[0006] The utility model aims to provide a rat restraint device to solve the problems existing in the prior art, effectively reducing the physical consumption of the operator in restraining the rat and reducing the labor consumption of the assistant.
[0007] To achieve the above-mentioned purpose, the utility model provides the following scheme:
[0008] The utility model provides a rat fixing device, including first fixed plate, second fixed plate, first fixed band and at least one second fixed band, the lower extreme of first fixed plate with the upper end fixed connection of second fixed plate, first fixed plate can bear the head of rat, both ends of first fixed band are fixedly established on first fixed plate, it has first restraint area between the middle part of first fixed band and first fixed plate, first restraint area is used for placing the head of rat, the middle part of first fixed band can press the head of rat on first fixed plate, each second fixed band is side by side arrangement, both ends of each second fixed band are fixedly established on second fixed plate, it has second restraint area between the middle part of each second fixed band and second fixed plate, second restraint area is used for placing the chest or abdomen of rat, the middle part of second fixed band can press the chest or abdomen of rat on second fixed plate.
[0009] Preferably, the number of second fixed bands is two, one second fixed band is used to contact the chest of the rat, and the other second fixed band is used to contact the abdomen of the rat.
[0010] Preferably, the first fixed band is a first elastic band, and the second fixed band is a second elastic band; the connection between one end of the first fixed band and the first fixed plate is detachable to adjust the length of the portion of the first fixed band placed in the first restraint area; and the connection between one end of the second fixed band and the second fixed plate is detachable to adjust the length of the portion of the second fixed band placed in the second restraint area.
[0011] Preferably, the width of the second fixed band is greater than or equal to 3 cm.
[0012] Preferably, the surface of the first fixed plate and the second fixed plate used to contact the rat is fixedly provided with a rubber layer.
[0013] Preferably, the connection between the first fixed plate and the second fixed plate is fixedly provided with a left front leg fixing rod and a right front leg fixing rod, the left front leg fixing rod is arranged on one side of the first fixed plate, and the right front leg fixing rod is arranged on the other side of the first fixed plate; the left front leg fixing rod is provided with a third fixed band, the third fixed band can fix the left front leg of the rat on the left front leg fixing rod when blood is collected from the left side of the rat; and the right front leg fixing rod is provided with a fourth fixed band, the fourth fixed band can fix the right front leg of the rat on the right front leg fixing rod when blood is collected from the right side of the rat.
[0014] Preferably, the third fixed band is a third elastic band, and the fourth fixed band is a fourth elastic band.
[0015] Preferably, the length of the first fixed plate is 5cm, and the width is 3cm; the length of the second fixed plate is 30cm, and the width is 6cm; the length of the left front leg fixed rod and the right front leg fixed rod is 6cm.
[0016] Preferably, the device further comprises a vertical rod and a stable platform, the bottom end of the vertical rod is fixed on the stable platform, the second fixed plate is hinged to the top end of the vertical rod, and the hinge between the second fixed plate and the vertical rod can be locked; the first fixed plate and the second fixed plate can be horizontal or vertical.
[0017] Preferably, the bottom surface of the stable platform is provided with a plurality of walking support wheels.
[0018] The device has the following technical effects compared with the prior art:
[0019] The rat fixing device provided by the device can fix the head of the rat through the first fixed belt and the first fixed plate, and fix the chest and abdomen of the rat through the second fixed belt and the second fixed plate, so that the rat is effectively fixed, the physical consumption of the operator in fixing the rat is effectively reduced, and the human consumption of the auxiliary fixing personnel is reduced. BRIEF DESCRIPTION OF DRAWINGS
[0020] In order to more clearly illustrate the technical scheme in the embodiments of the device or the prior art, the drawings needed in the embodiments will be briefly introduced as follows. Obviously, the drawings in the following description are only some embodiments of the device, and other drawings can be obtained by those skilled in the art without creative labor on the basis of the drawings.
[0021] Figure 1 Figure 1 is a schematic view of the rat fixing device provided by the device when the first fixed plate and the second fixed plate are vertical;
[0022] Figure 2 Figure 2 is a side view of the rat fixing device in Figure 1; Figure 1
[0023] Figure 3 Figure 3 is a perspective view of the rat fixing device in Figure 1; Figure 1
[0024] Figure 4 Figure 4 is a schematic view of the rat fixing device provided by the device when the first fixed plate and the second fixed plate are horizontal;
[0025] Figure 5 Figure 5 is a side view of the rat fixing device in Figure 4; Figure 4
[0026] Figure 6 Figure 6 is a perspective view of the rat fixing device in Figure 4.Figure 4 A three-dimensional diagram of a rat restraint device;
[0027] In the diagram: 1-First fixing plate, 2-Second fixing plate, 3-First fixing strap, 4-Second fixing strap, 5-Left front leg fixing rod, 6-Right front leg fixing rod, 7-Upright pole, 8-Stabilizing platform, 9-Walking support wheel. Detailed Implementation
[0028] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.
[0029] The purpose of this invention is to provide a rat restraint device to solve the problems existing in the prior art, effectively reduce the physical exertion of the operator in restraining the rat, and reduce the manpower consumption of the auxiliary restraint personnel.
[0030] To make the above-mentioned objectives, features and advantages of this utility model more apparent and understandable, the utility model will be further described in detail below with reference to the accompanying drawings and specific embodiments.
[0031] like Figures 1-6 As shown, this utility model provides a rat restraint device, including a first fixing plate 1, a second fixing plate 2, a first fixing strap 3, and at least one second fixing strap 4. The lower end of the first fixing plate 1 is fixedly connected to the upper end of the second fixing plate 2. The first fixing plate 1 can support the rat's head. Both ends of the first fixing strap 3 are fixedly mounted on the first fixing plate 1. The middle part of the first fixing strap 3 has a first binding area between itself and the first fixing plate 1. The first binding area is used to place the rat's head. The middle part of the first fixing strap 3 can press the rat's head tightly onto the first fixing plate 1. Each second fixing strap 4 is arranged side by side. Both ends of each second fixing strap 4 are fixedly mounted on the second fixing plate 2. The middle part of each second fixing strap 4 has a second binding area between itself and the second fixing plate 2. The second binding area is used to place the rat's chest or abdomen. The middle part of the second fixing strap 4 can press the rat's chest or abdomen tightly onto the second fixing plate 2.
[0032] The rat restraint device provided by this utility model uses a first fixing strap 3 and a first fixing plate 1 to fix the rat's head, and a second fixing strap 4 and a second fixing plate 2 to fix the rat's chest and abdomen, thereby achieving effective restraint of the rat. This can effectively reduce the physical exertion of the operator in restraining the rat and reduce the manpower consumption of the auxiliary restraint personnel.
[0033] The specific use method of the rat fixing device is provided in the utility model.
[0034] (1)Prepare disinfection cotton swab, alcohol, syringe, EP tube, shaver and dry cotton ball and other materials.
[0035] (2)Grasp the rat and check the number, fix the rat on the rat fixing device provided in the utility model, skin the neck with the shaver, expose the needle insertion position, vertically fix the first fixed plate 1 and the second fixed plate 2, and make the rat in the operation state.
[0036] (3)Disinfect the blood sampling area of the rat with the disinfection cotton swab, and wipe dry with the dry cotton swab.
[0037] (4)Insert the needle into the syringe at the bottom of the triangular fossa of the rat neck and the head at a certain angle, and insert into the anterior vena cava towards the heart.
[0038] (5)After rapid blood sampling, transfer to the EP tube, press the hemostasis with the dry cotton ball at the rat blood sampling place, and make the rat return to the horizontal position.
[0039] (6)Take off the rat, and operate the next rat.
[0040] As a more preferred embodiment of the embodiment, the number of the second fixing belts 4 is two, one second fixing belt 4 is used for contacting with the chest of the rat, and the other second fixing belt 4 is used for contacting with the abdomen of the rat, the structure is simple, and the chest and the abdomen of the rat can be effectively fixed.
[0041] As a more preferred embodiment of the embodiment, the first fixing belt 3 is a first elastic belt, and the second fixing belt 4 is a second elastic belt; the connection between one end of the first fixing belt 3 and the first fixed plate 1 can be disassembled to adjust the length of the part on the first fixing belt 3 placed in the first restraint area; the connection between one end of the second fixing belt 4 and the second fixed plate 2 can be disassembled to adjust the length of the part on the second fixing belt 4 placed in the second restraint area, which is convenient for manufacturing and using, is convenient for ensuring that the rat is moderately loose, and after use, the first fixing belt 3 and the second fixing belt 4 can be opened to take out the rat.
[0042] As a more preferred embodiment of the embodiment, the width of the second fixing belt 4 is greater than or equal to 3cm, which can effectively fix the rat and avoid hurting the rat.
[0043] Further, the surface for contacting with the rat on the first fixed plate 1 and the second fixed plate 2 is fixedly provided with a rubber layer, which can make the rat warm and comfortable.
[0044] Further, the connecting part of the first fixing plate 1 and the second fixing plate 2 is fixedly provided with a left front leg fixing rod 5 and a right front leg fixing rod 6, the left front leg fixing rod 5 is arranged on one side of the first fixing plate 1, and the right front leg fixing rod 6 is arranged on the other side of the first fixing plate 1; the left front leg fixing rod 5 is provided with a third fixing belt, and the third fixing belt can fix the left front leg of the rat on the left front leg fixing rod 5 when blood is collected from the left side of the rat; the right front leg fixing rod 6 is provided with a fourth fixing belt, and the fourth fixing belt can fix the right front leg of the rat on the right front leg fixing rod 6 when blood is collected from the right side of the rat, so as to facilitate blood collection operation.
[0045] As a more preferred embodiment of the present embodiment, the third fixing belt is a third elastic belt, and the fourth fixing belt is a fourth elastic belt, which is convenient for manufacturing and using, and after use, the third fixing belt and the fourth fixing belt can be opened to take out the rat.
[0046] As a more preferred embodiment of the present embodiment, the length of the first fixing plate 1 is 5cm, and the width is 3cm; the length of the second fixing plate 2 is 30cm, and the width is 6cm; the length of the left front leg fixing rod 5 and the right front leg fixing rod 6 is 6cm, and the structure is compact, which is convenient for manufacturing and using.
[0047] Further, the rat fixing device also comprises a stand rod 7 and a stable platform 8, the bottom end of the stand rod 7 is fixedly arranged on the stable platform 8, the second fixing plate 2 is hingedly connected with the top end of the stand rod 7, the hinge connection between the second fixing plate 2 and the stand rod 7 can be locked, the first fixing plate 1 and the second fixing plate 2 can be horizontal or vertical, the first fixing plate 1 and the second fixing plate 2 can be conveniently fixed when horizontal, and the first fixing plate 1 and the second fixing plate 2 can be conveniently used for blood collection operation when vertical.
[0048] As a more preferred embodiment of the present embodiment, the height of the stand rod 7 is 30cm, which is convenient for operation of the rat.
[0049] Further, the bottom surface of the stable platform 8 is provided with a plurality of walking supporting wheels 9, which is convenient for flexible transfer of the rat position.
[0050] The principle and implementation mode of the specific examples are described in the present application, and the above examples are only used to help understand the method and core idea of the present application; meanwhile, for the general technical personnel in the field, according to the idea of the present application, the specific implementation mode and application range will be changed. In conclusion, the content of the specification should not be understood as the limitation of the present application.
Claims
1. A rat restraint device, characterized by: The first fixed plate and the second fixed plate are fixedly connected at the lower end of the first fixed plate and the upper end of the second fixed plate, the first fixed plate can bear the head of a rat, the two ends of the first fixed band are fixedly arranged on the first fixed plate, the middle part of the first fixed band and the first fixed plate have a first restraint area, the first restraint area is used for placing the head of a rat, and the middle part of the first fixed band can press the head of a rat on the first fixed plate, each second fixed band is arranged side by side, the two ends of each second fixed band are fixedly arranged on the second fixed plate, the middle part of each second fixed band and the second fixed plate have a second restraint area, the second restraint area is used for placing the chest or abdomen of a rat, and the middle part of the second fixed band can press the chest or abdomen of a rat on the second fixed plate.
2. The rat restraint device of claim 1, wherein: The number of the second fixed bands is two, one of the second fixed bands is used for contacting the chest of a rat, and the other of the second fixed bands is used for contacting the abdomen of a rat.
3. The rat restraint device of claim 1, wherein: The first fixed band is a first elastic band, and the second fixed band is a second elastic band; the connection between one end of the first fixed band and the first fixed plate can be disassembled to adjust the length of the part of the first fixed band arranged in the first restraint area; and the connection between one end of the second fixed band and the second fixed plate can be disassembled to adjust the length of the part of the second fixed band arranged in the second restraint area.
4. The rat restraint device of claim 3, wherein: The width of the second fixed band is greater than or equal to 3 cm.
5. The rat restraint device of claim 1, wherein: The surfaces of the first fixed plate and the second fixed plate for contacting a rat are fixedly provided with rubber layers.
6. The rat restraint device of claim 1, wherein: The connection between the first fixed plate and the second fixed plate is fixedly provided with a left front leg fixing rod and a right front leg fixing rod, the left front leg fixing rod is arranged on one side of the first fixed plate, the right front leg fixing rod is arranged on the other side of the first fixed plate, a third fixed band is arranged on the left front leg fixing rod, the third fixed band can fix the left front leg of a rat on the left front leg fixing rod when blood is collected from the left side of the rat, a fourth fixed band is arranged on the right front leg fixing rod, and the fourth fixed band can fix the right front leg of a rat on the right front leg fixing rod when blood is collected from the right side of the rat.
7. The rat restraint device of claim 6, wherein: The third fixed band is a third elastic band, and the fourth fixed band is a fourth elastic band.
8. The rat restraint device of claim 6, wherein: The length of the first fixed plate is 5 cm, and the width is 3 cm; the length of the second fixed plate is 30 cm, and the width is 6 cm; and the length of the left front leg fixing rod and the right front leg fixing rod is 6 cm.
9. The rat restraint device of claim 1, wherein: The first fixed plate and the second fixed plate can be horizontal or vertical.
10. The rat restraint device of claim 9, wherein: The bottom surface of the stable platform is provided with a plurality of walking support wheels.