Filtering equipment for drug intermediate synthesis

Abstract

The utility model discloses filtering equipment for synthesis of a drug intermediate, which relates to the technical field of synthesis of drug intermediates and comprises a support frame, and a filter cartridge is arranged above the support frame. Various impurities and peculiar smells in the drug intermediates can be comprehensively and finely removed, the coarse filter screen firstly intercepts large impurities, the fine filter screen further removes small particles, and the activated carbon adsorption layer adsorbs tiny impurities and peculiar smells, so that the purity of the drug intermediates is greatly improved, and a high-quality raw material guarantee is provided for subsequent drug production; the eccentric wheel on the rotating shaft is driven by the motor to rotate, so that the fixing ring, the connecting ring and the filter cartridge vibrate up and down in a reciprocating manner, materials flow more smoothly on the filter screens (a coarse filter screen and a fine filter screen) under the reset action of the spring I in the vibration process, the blockage condition is reduced, and the filtering speed is increased.

Description

TECHNICAL FIELD

[0001] The utility model relates to the technical field of drug intermediate synthesis, especially to a filter equipment for drug intermediate synthesis. BACKGROUND

[0002] In the synthesis process of drug intermediates, the filtration link is the key step to ensure product quality and purity, and the purity and quality of drug intermediates as intermediate products in the drug synthesis process directly affect the efficacy, safety and stability of the final drug.

[0003] In practical application, the filter equipment for drug intermediate synthesis usually needs the following technologies:

[0004] 1. Filtration capacity, which can effectively remove impurities of different sizes and types to ensure the purity of intermediates;

[0005] 2. Anti-blocking mechanism to facilitate smooth passage of materials through the filter layer and improve filtration efficiency

[0006] At present, the traditional filter equipment for drug intermediate synthesis has poor filtration effect in actual use, cannot completely remove impurities, affects product quality, and is prone to filter screen blockage, resulting in slow filtration speed and low efficiency. UTILITY MODEL CONTENT

[0007] (I) Technical problem solved

[0008] In view of the deficiencies of the prior art, the utility model provides a filter equipment for drug intermediate synthesis, which solves the technical problems of the traditional filter equipment for drug intermediate synthesis, such as poor filtration effect in actual use, inability to completely remove impurities, influence on product quality, and prone to filter screen blockage, resulting in slow filtration speed and low efficiency.

[0009] (II) Technical scheme

[0010] To achieve the above purpose, the utility model is implemented by the following technical scheme:

[0011] The utility model provides a filter equipment for drug intermediate synthesis, including support frame, the top of support frame is provided with filter cartridge, the filter cartridge is sequentially provided with coarse filter screen, fine filter screen and activated carbon adsorption layer from top to bottom, the upper end of filter cartridge is provided with feed inlet, the bottom of filter cartridge is provided with discharge pipe, the filter cartridge is fixedly sleeved with connecting ring, the both sides of connecting ring upper surface are all set up with the installation mouth, the support frame is installed with fixed ring, the both sides of fixed ring upper end are all fixedly installed with mounting block, two mounting blocks are respectively active and are passed through installation mouth, be provided with fixed component on the fixed ring, fixed component includes press ring, the both sides of fixed ring end are all fixedly installed with lug plate, the motor is fixedly installed on the support frame, the output shaft of motor is fixedly connected with the pivot, the pivot is fixedly installed with eccentric wheel, and the eccentric wheel is located the bottom of fixed ring.

[0012] Preferably: the press ring is below the fixed ring, two lock rods are fixedly installed on the upper end of the press ring, both the lock rods are active and pass through the fixed ring and are respectively active and pass through the two mounting blocks, spring two is fixedly connected between the press ring and the fixed ring.

[0013] Preferably: the surface of each mounting block is provided with a groove, the both sides of the upper surface of the connecting ring are provided with through holes, the both sides of the upper end of the support frame are fixedly installed with limit rods, each limit rod is respectively active and passes through the lug plate, and spring one is active and is sleeved on each limit rod.

[0014] Preferably: the bottom end of the connecting ring is conical design, the connecting ring is installed on the upper end of the fixed ring, the discharge pipe is active and passes through the fixed ring, the support frame is placed with a collection cylinder, and the discharge pipe is active and inserted into the collection cylinder.

[0015] (Three) beneficial effects

[0016] I. Through the layered filtration of coarse filter screen, fine filter screen and activated carbon adsorption layer in the filter cartridge, various impurities and odors in the drug intermediates can be comprehensively and finely removed, the coarse filter screen first intercepts larger impurities, the fine filter screen further removes smaller particles, and the activated carbon adsorption layer adsorbs tiny impurities and odors, greatly improving the purity of the drug intermediates and providing high-quality raw material guarantee for subsequent drug production. The eccentric wheel on the pivot is driven to rotate by the motor, so that the fixed ring, the connecting ring and the filter cartridge reciprocate up and down, and in the vibration process, the reset action of spring one makes the flow of materials on the filter screen (coarse filter screen, fine filter screen) more smooth, reduces the plugging condition, and speeds up the filtering speed. At the same time, the limit rods ensure the stability and direction of vibration, improve the efficiency and stability of filtration.

[0017] II. When installing, align the installation port on the connecting ring with the installation block, pass the installation block through to achieve preliminary installation, and finally lock by pressing the pressing ring and the locking rod. When disassembling, press the pressing ring downward to make the locking rod disengage, rotate the filter cartridge to make the installation port coincide with the installation block, and then disassemble, which is convenient for replacing the filter cartridge and using. BRIEF DESCRIPTION OF DRAWINGS

[0018] The above description is only a summary of the technical scheme of the present application. In order to more clearly understand the technical means of the present application, and can be implemented in accordance with the content of the specification, the following is a detailed description of the preferred embodiments of the present application with reference to the accompanying drawings.

[0019] Figure 1 The structure diagram of the whole filter equipment for synthesizing pharmaceutical intermediates of the present application is shown in the figure.

[0020] Figure 2 The structure diagram of the filter cartridge of the present application is shown in the figure.

[0021] Figure 3 The structure diagram of the fixed ring of the present application is shown in the figure.

[0022] Figure 4 The structure diagram of the eccentric wheel of the present application is shown in the figure.

[0023] Legend: 1, support frame; 11, limiting rod; 12, spring I; 13, collection cylinder; 2, filter cartridge; 21, coarse filter screen; 22, fine filter screen; 23, activated carbon adsorption layer; 24, feed inlet; 25, discharge pipe; 3, connecting ring; 31, through hole; 32, installation port; 4, fixed ring; 41, installation block; 43, ear plate; 44, groove; 5, pressing ring; 51, spring II; 52, locking rod; 6, motor; 61, rotating shaft; 62, eccentric wheel. DETAILED DESCRIPTION

[0024] The embodiment of the application provides a filtering device for drug intermediate synthesis, which effectively solves the problem of poor filtering effect, incomplete removal of impurities, influence on product quality, filter screen blockage, slow filtering speed and low efficiency of the conventional filtering device for drug intermediate synthesis in actual use, can completely and finely remove various impurities and odors in the drug intermediate, the coarse filter screen first intercepts large impurities, the fine filter screen further removes small particles, and the activated carbon adsorption layer adsorbs small impurities and odors, greatly improving the purity of the drug intermediate and providing high-quality raw material guarantee for subsequent drug production, the eccentric wheel on the rotating shaft is driven by the motor to rotate, the fixed ring, the connecting ring and the filter cylinder are reciprocated up and down, in the vibration process, the reset action of the spring one makes the flow of the material on the filter screen (the coarse filter screen and the fine filter screen) more smooth, reduces the blockage and speeds up the filtering speed, meanwhile, the limiting rod ensures the stability and direction of the vibration, and the filtering efficiency and stability are improved.

[0025] The embodiment is as shown in Figure 1 , Figure 2 , Figure 3 and Figure 4 , the technical scheme in the embodiment of the application effectively solves the technical problems of poor filtering effect, incomplete removal of impurities, influence on product quality, filter screen blockage, slow filtering speed and low efficiency of the conventional filtering device for drug intermediate synthesis in actual use, and the overall idea is as follows:

[0026] The utility model provides a filter equipment for drug intermediate synthesis, including support frame 1, the top of support frame 1 is provided with filter cartridge 2, coarse filter screen 21, fine filter screen 22 and activated carbon adsorption layer 23 are sequentially arranged from top to bottom in filter cartridge 2, the upper end of filter cartridge 2 is provided with feed inlet 24, the bottom of filter cartridge 2 is provided with discharge pipe 25, the fixed sleeve of filter cartridge 2 is connected with connecting ring 3, the both sides of connecting ring 3 upper surface are all seted up with mounting 32, the fixed ring 4 is installed on support frame 1, the both sides of fixed ring 4 upper end are all fixedly installed with mounting block 41, two mounting blocks 41 respectively move and pass through mounting 32, be provided with fixed assembly on fixed ring 4, and fixed assembly includes press ring 5, the both sides of fixed ring 4 end part are all fixedly installed with ear plate 43, motor 6 is fixedly installed on support frame 1, the output shaft of motor 6 is fixedly connected with pivot 61, pivot 61 is fixedly installed with eccentric wheel 62, and eccentric wheel 62 is located at the bottom of fixed ring 4, press ring 5 is located below fixed ring 4, two lock bars 52 are fixedly installed on press ring 5 upper end, two lock bars 52 all move and pass through fixed ring 4, and respectively move and pass through two mounting blocks 41, and spring no.Then rotate the filter cartridge 2, so that the two mounting blocks 41 set in the connecting ring 3 surface, then loosen the press ring 5, using the reset action of spring two 51, so that the press ring 5 and the lock rod 52 reset, so that the two lock rods 52 through the through hole 31, and reinserted in the mounting block 41, complete the limiting locking of the connecting ring 3, when the filter cartridge 2 is disassembled, similarly, press the press ring 5 downward, so that the two lock rods 52 are separated from the through hole 31, at this time the connecting ring 3 is not limited by the blocking, rotate the filter cartridge 2 so that the two mounting ports 32 coincide with the mounting block 41, and then the filter cartridge 2 can be disassembled upward, the installation and disassembly of the filter cartridge 2 is simple and convenient.

[0027] Working principle:

[0028] First, in the process of drug intermediate synthesis, the material to be filtered enters the filter cartridge 2 from the feed port 24, first passes through the coarse filter screen 21, and the larger impurities and particles are intercepted, then the material continues to pass through the fine filter screen 22, further removing small particle substances, finally, the material passes through the activated carbon adsorption layer 23, adsorbing the tiny impurities, peculiar smell, etc. in it, start the motor 6, so that the rotating shaft 61 rotates, through the rotation of the rotating shaft 61 drives the eccentric wheel 62 to rotate, through the rotation of the eccentric wheel 62 will exert an upward thrust on the fixed ring 4, so that the fixed ring 4, the connecting ring 3 and the filter cartridge 2 move up, using the reset action of spring one 12, the fixed ring 4, the connecting ring 3 and the filter cartridge 2 reset downward, so that the fixed ring 4, the connecting ring 3 and the filter cartridge 2 reciprocate up and down, under the action of vibration, the flow of material on the filter screen is more smooth, reducing the filter screen blockage, speeding up the filtering speed, improving the filtering efficiency, when the filtering is completed, the pure drug intermediate is discharged from the discharge pipe 25 to the collecting cylinder 13.

[0029] Second, in the installation of filter cartridge 2, the installation port 32 is aligned with the installation block 41, so that the two installation blocks 41 smoothly pass through the installation port 32, so that the filter cartridge 2 is installed on the fixed ring 4, realizing the preliminary installation of the filter cartridge 2, then press the press ring 5 downward, so that the two lock rods 52 move down, then rotate the filter cartridge 2, so that the two installation blocks 41 are sleeved on the surface of the connecting ring 3, then release the press ring 5, and reset the press ring 5 and the lock rod 52 by the reset action of the spring 2, so that the two lock rods 52 pass through the through hole 31 and are reinserted in the installation block 41, complete the limiting locking of the connecting ring 3, when disassembling the filter cartridge 2, similarly, press the press ring 5 downward, so that the two lock rods 52 are separated from the through hole 31, at this time the connecting ring 3 is not limited by the blocking, rotate the filter cartridge 2 so that the two installation ports 32 are respectively coincided with the installation block 41, and the filter cartridge 2 can be disassembled upward, the installation and disassembly of the filter cartridge 2 are relatively simple and convenient. Finally, it should be pointed out that: obviously, the above examples are only examples for clearly illustrating the present application, and are not limited to the embodiments. For ordinary skilled in the art, on the basis of the above description, other different forms of changes or variations can also be made. Here, it is not necessary and impossible to enumerate all the embodiments. The obvious changes or variations derived therefrom are still within the protection scope of the present application.

Claims

1. A filtering device for the synthesis of pharmaceutical intermediates, comprising a support frame (1), characterized in that: The upper part of the support frame (1) is provided with a filter cartridge (2), the filter cartridge (2) is sequentially provided with a coarse filter screen (21), a fine filter screen (22) and an activated carbon adsorption layer (23) from top to bottom, the upper end of the filter cartridge (2) is provided with a feeding port (24), the bottom end of the filter cartridge (2) is provided with a discharging pipe (25), the filter cartridge (2) is fixedly sleeved with a connecting ring (3), and the upper surface of the connecting ring (3) is provided with mounting ports (32) on both sides. Wherein, the support frame (1) is provided with a fixed ring (4), the upper end of the fixed ring (4) is provided with mounting blocks (41) on both sides, the two mounting blocks (41) are respectively movably penetrated through the mounting ports (32), and the fixed ring (4) is provided with a fixing assembly, and the fixing assembly comprises a pressing ring (5). Wherein, the both ends of the fixed ring (4) are fixedly provided with ear plates (43), the support frame (1) is fixedly provided with a motor (6), the output shaft of the motor (6) is fixedly connected with a rotating shaft (61), the rotating shaft (61) is fixedly provided with an eccentric wheel (62), and the eccentric wheel (62) is located at the bottom of the fixed ring (4).

2. A filter apparatus for the synthesis of pharmaceutical intermediates according to claim 1, characterized in that: The pressing ring (5) is located below the fixed ring (4), and the upper end of the pressing ring (5) is fixedly provided with two lock rods (52). Wherein, the two lock rods (52) are movably penetrated through the fixed ring (4) and movably penetrated through the two mounting blocks (41) respectively.

3. A filter apparatus for the synthesis of pharmaceutical intermediates according to claim 2, characterized in that: The spring two (51) is fixedly connected between the pressing ring (5) and the fixed ring (4).

4. A filter apparatus for the synthesis of pharmaceutical intermediates according to claim 3, characterized in that: The surface of each mounting block (41) is provided with a groove (44). Wherein, the upper surface of the connecting ring (3) is provided with through holes (31) on both sides.

5. A filter apparatus for the synthesis of pharmaceutical intermediates according to claim 4, characterized in that: The upper end of the support frame (1) is fixedly provided with limiting rods (11) on both sides, and the limiting rods (11) are movably penetrated through the ear plates (43) respectively. Wherein, the spring one (12) is movably sleeved on each limiting rod (11).

6. A filter apparatus for the synthesis of pharmaceutical intermediates according to claim 5, characterized in that: The bottom end of the connecting ring (3) is designed in a conical shape, the connecting ring (3) is installed at the upper end of the fixed ring (4), and the discharging pipe (25) is movably penetrated through the fixed ring (4). Wherein, the support frame (1) is placed with a collecting cylinder (13), and the discharging pipe (25) is movably inserted into the collecting cylinder (13).

Images