Sample processing device

By designing a sample processing device with a turntable assembly and a puncture positioning assembly, the problems of complex structure and low efficiency of manual sample loading in traditional sample analyzers are solved, realizing efficient and reliable full-process operation of sample processing in a small sample analyzer.

CN223808219UActive Publication Date: 2026-01-16SHANGHAI I-READER BIOTECH CO LTD
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Patent Information

Application Number
CN202423303603.7
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-12-30
Publication Date
2026-01-16
Estimated Expiration
2034-12-30

AI Technical Summary

Technical Problem

Traditional portable sample analyzers have complex structures and large space requirements for automated sample loading instruments, while manual sample loading is inefficient and difficult to apply to small sample analyzers and emergency scenarios.

Method used

Design a sample processing device including a turntable assembly, a puncture positioning assembly, and a sample unloading assembly. The turntable is equipped with multiple cavities. The sample injection, mixing, sampling, and unloading are achieved through the rotation of the turntable, and the entire process is automated.

Benefits of technology

It achieves high efficiency and reliability in small-batch sample processing, meets the sample preprocessing requirements in limited space, and improves the efficiency and reliability of sample processing.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model provides a sample treatment device, and relates to the technical field of medical equipment, the sample treatment device comprises a turntable assembly, a puncture positioning assembly and a sample unloading assembly which are arranged on a wallboard, the turntable assembly comprises a turntable, a plurality of accommodating cavities are circumferentially formed in the turntable and are used for accommodating sampling tubes, and the puncture positioning assembly and the sample unloading assembly are respectively positioned on one side of the turntable; the rotating disc rotates to drive the sampling pipe to rotate to stations corresponding to the puncture positioning assembly and the sample unloading assembly respectively, the puncture positioning assembly performs puncture sampling on the sampling pipe, and the sample unloading assembly unloads the sampling pipe from the rotating disc. The multiple containing cavities are formed in the rotating disc, related operation can be carried out on the multiple sampling pipes at the same time, all the processes of sample pretreatment are completed through driving of the rotating disc, the sample treatment efficiency is improved, and meanwhile the limited design space is met. The whole device is stable in structure and ensures the reliability of sample treatment. The full-flow operation of small-scale batch sample loading, uniform mixing, sampling and sample unloading is realized, and the sample processing efficiency and reliability are improved.
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Description

Technical Field

[0001] This application relates to the field of medical device technology, specifically to a sample processing device. Background Technology

[0002] Traditional portable sample analyzers typically use either automated sample loading instruments or manual sample loading. Automated sample loading instruments often have complex sample processing devices that occupy a large space or are exposed on the outside of the machine, making them unsuitable for small sample analyzers. Manual sample loading requires thorough mixing of blood samples before testing, and single-tube manual loading is inefficient and complex. A single loading station cannot meet the requirements for continuous loading, making it unsuitable for emergency scenarios. Utility Model Content

[0003] The purpose of this application is to provide a sample processing device that can realize the entire process of small-batch sample loading, mixing, sampling and unloading, thereby improving the efficiency and reliability of sample processing.

[0004] In one aspect of this application, a sample processing device is provided, including a turntable assembly, a puncture positioning assembly, and a sample unloading assembly disposed on a wall panel. The turntable assembly includes a turntable with a plurality of accommodating cavities arranged circumferentially for accommodating sampling tubes. The puncture positioning assembly and the sample unloading assembly are respectively located on one side of the turntable. The turntable rotates, causing the sampling tubes to rotate to the positions corresponding to the puncture positioning assembly and the sample unloading assembly, respectively. The puncture positioning assembly punctures and samples the sampling tubes, and the sample unloading assembly unloads the sampling tubes from the turntable.

[0005] Optionally, the turntable assembly includes a motor and a spindle connected to the motor, the spindle being connected to the turntable.

[0006] Optionally, the turntable assembly further includes a first retaining ring and a second retaining ring, which are disposed opposite to each other and surround the outer peripheral wall of the turntable with the sample unloading assembly to block the opening of the receiving cavity.

[0007] Optionally, the first retaining ring is provided with a sample inlet, which is connected to a receiving cavity near the sample inlet.

[0008] Optionally, the puncture positioning assembly includes a mounting plate fixed to the wall panel and a limiting block fixed to the mounting plate. The mounting plate extends from the wall panel to the outer periphery of the turntable and the disc surface of the turntable away from the wall panel, and forms a bent portion at the disc surface of the turntable. The limiting block is fixed on the bent portion and located between the bent portion and the turntable. An elastic element is also provided between the mounting plate and the limiting block.

[0009] Optionally, the end face of the mounting plate facing the receiving cavity forms a puncture port, and the puncture port communicates with the receiving cavity.

[0010] Optionally, the sample unloading assembly includes a base fixed to the wall panel, a slide rail and a motor are provided on the base, the motor is connected to a slider, the slider is connected to the slide rail, and a movable door is provided on the slider so that the movable door moves along the slide rail. The direction of movement of the movable door along the slide rail is perpendicular to the surface of the turntable, and the movable door corresponds to the opening of the receiving cavity at the bottom of the turntable.

[0011] Optionally, it also includes detection components, which are respectively located in the accommodating cavity near the sample inlet to detect whether the sampling tube has been properly inserted, in the accommodating cavity near the sample unloading component to detect whether the sampling tube has been completely unloaded, and in the accommodating cavity at the bottom of the turntable to detect whether the turntable is accurately positioned.

[0012] Optionally, the detection component includes an optical coupler or an optical sensor.

[0013] Optionally, it also includes a controller, which is electrically connected to the detection component, the turntable component, the sample unloading component, and the puncture positioning component, respectively.

[0014] The sample processing device provided in this application embodiment includes a turntable assembly, a puncture positioning assembly, and a sample unloading assembly mounted on a wall panel. The turntable assembly includes a turntable with multiple circumferentially arranged cavities for accommodating sampling tubes. The puncture positioning assembly and the sample unloading assembly are located on opposite sides of the turntable. The turntable rotates, causing the sampling tubes to rotate to their corresponding positions. The puncture positioning assembly punctures and extracts samples from the sampling tubes, and the sample unloading assembly removes the samples from the turntable. This device enables sample injection, mixing, sampling, and unloading. It features a sample puncture position, which, in conjunction with the puncture positioning assembly, allows for sample puncture and aspiration. After sample processing, the device can be unloaded. The multiple cavities on the turntable allow for simultaneous operation on multiple sampling tubes. The turntable drives all pre-processing steps, improving sample processing efficiency while meeting limited design space requirements. Furthermore, the entire device has a stable structure, ensuring reliable sample processing. It enables the entire process of small-batch sample loading, mixing, sampling, and unloading, improving the efficiency and reliability of sample processing. Attached Figure Description

[0015] To more clearly illustrate the technical solutions of the embodiments of this application, the accompanying drawings used in the embodiments of this application will be briefly introduced below. It should be understood that the following drawings only show some embodiments of this application and should not be regarded as a limitation of the scope. For those skilled in the art, other related drawings can be obtained based on these drawings without creative effort.

[0016] Figure 1 This is one of the schematic diagrams of the sample processing device provided in this embodiment;

[0017] Figure 2 This is the second schematic diagram of the sample processing device provided in this embodiment;

[0018] Figure 3 This is the third schematic diagram of the sample processing device provided in this embodiment.

[0019] Icons: 10-Wall panel; 11-Turntable; 110-Cavity; 111-Groove; 112-First retaining ring; 113-Second retaining ring; 114-Cavity opening; 115-Sample inlet; 116-Mandrel; 117-Noise reduction component; 118-Motor; 120-Motor; 121-Slide rail; 122-Sliding door; 123-Base; 130-Mounting plate; 130a-Piercing port; 131-Bending part; 132-Limiting block; 141-Sample injection detection assembly; 142-Sample unloading detection assembly; 142a-Optical coupler plate; 142b-Optical coupler; 142c-Optical coupler baffle; 143-Sample positioning assembly; 20-Sampling tube. Detailed Implementation

[0020] The technical solutions in the embodiments of this application will be clearly and completely described below with reference to the accompanying drawings.

[0021] In the description of this application, it should be noted that the terms "inner" and "outer," etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings, or the orientation or positional relationship commonly used when the product is in use. They are used only for the convenience of describing this application and for simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on this application. Furthermore, the terms "first," "second," etc., are used only to distinguish descriptions and should not be construed as indicating or implying relative importance.

[0022] It should also be noted that, unless otherwise explicitly specified and limited, the terms "setup" and "connection" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a direct connection or an indirect connection through an intermediate medium; and they can refer to the internal connection of two components. Those skilled in the art can understand the specific meaning of the above terms in this application based on the specific circumstances.

[0023] Based on the limitations of current sample analyzers in terms of application scenarios such as sample loading and mixing, this application provides a sample processing device that has a small footprint, simple structure, and accurate positioning, and can realize functions such as automatic sample loading, mixing, puncture positioning, and sample unloading in small batches.

[0024] Specifically, please refer to Figure 1 As shown, this application provides a sample processing device, including: a turntable assembly, a puncture positioning assembly, and a sample unloading assembly disposed on a wall panel 10. The turntable assembly includes a turntable 11, which has a plurality of accommodating cavities 110 arranged circumferentially for accommodating sampling tubes 20. The puncture positioning assembly and the sample unloading assembly are respectively located on one side of the turntable 11. The turntable 11 rotates, causing the sampling tubes 20 to rotate to the positions corresponding to the puncture positioning assembly and the sample unloading assembly, respectively. The puncture positioning assembly punctures and samples the sampling tubes 20, and the sample unloading assembly unloads the sampling tubes 20 from the turntable 11.

[0025] Sampling tubes 20 are disposed within the receiving cavities 110 of the turntable 11. Multiple receiving cavities 110 are arranged circumferentially around the turntable 11, with one sampling tube 20 housed in each cavity. For example, the turntable 11 is circular. Multiple sampling tubes 20 are arranged in a circumferential ring around the turntable 11, with each sampling tube 20 arranged radially, its bottom pointing towards the center of the turntable 11. When the turntable 11 rotates, it drives the multiple sampling tubes 20 to rotate, achieving the effect of simultaneously mixing the multiple sampling tubes 20.

[0026] When the turntable 11 rotates to different positions, the same sampling tube 20 can be in different positions. The puncture positioning component and the sample unloading component are located on one side of the turntable 11 and correspond to the cavity opening 114 of the receiving cavity 110. When the sampling tube 20 rotates with the turntable 11 to the puncture position corresponding to the puncture positioning component, the puncture positioning component performs a puncture operation on the sampling tube 20; when the sampling tube 20 rotates to the sample unloading position corresponding to the sample unloading component, the sample unloading component unloads the sampling tube 20 from the turntable 11, thus completing one operation cycle.

[0027] The sample processing device provided in this application embodiment can realize sample injection, shaking, sampling and unloading. The device is equipped with a sample puncture position, which, together with the puncture positioning component, can perform functions such as puncture and sample aspiration. After the sample processing is completed, the sample can be unloaded.

[0028] The multiple accommodating cavities 110 on the turntable 11 allow for simultaneous operation on multiple sampling tubes 20. The turntable 11 drives all pre-processing steps (including sample injection, transport, rotation and mixing, puncture sampling, and sample removal) to improve sample processing efficiency while meeting limited design space requirements. Furthermore, the entire device is structurally stable, ensuring reliable sample processing.

[0029] In some embodiments, such as Figure 2 As shown, the sample processing device is fixed on the wall panel 10. The turntable assembly includes a motor 118 and a spindle 116. The spindle 116 passes through the wall panel 10 and is connected to the motor 118. The spindle 116 is also fixedly connected to the turntable 11. The motor 118 drives the turntable 11 to rotate through the spindle 116, so that the sampling tube 20 inside the turntable 11 rotates to different positions.

[0030] The turntable assembly also includes a first retaining ring 112 and a second retaining ring 113. The first retaining ring 112 and the second retaining ring 113 surround the outer peripheral wall of the turntable 11, which can block the cavity opening 114 of the accommodating cavity 110 of the turntable 11, and prevent the sampling tube 20 in the cavity opening 114 from sliding out of the accommodating cavity 110 under the action of gravity and centrifugal force.

[0031] The first retaining ring 112 is located on one side of the turntable 11 and is fixedly connected to the wall plate 10. The first retaining ring 112 is provided with a sample inlet 115, which is connected to the receiving cavity 110 on the turntable 11 located at the sample inlet position. The sampling tube 20 enters the receiving cavity 110 of the turntable 11 through the sample inlet 115. The second retaining ring 113 is located on the other side of the turntable 11 and is also fixed to the wall plate 10. A noise reduction component 117, such as noise reduction cotton, is also provided on the inner side of the second retaining ring 113, that is, between the second retaining ring 113 and the turntable 11, to reduce the noise generated by the collision between the sampling tube 20 and the second retaining ring 113 during the rotation and mixing process.

[0032] The puncture positioning assembly is located directly above the turntable 11. The puncture positioning assembly includes a mounting plate 130, a limiting block 132, and several elastic elements, such as springs. The springs are located between the mounting plate 130 and the limiting block 132, with one end of the spring fixed to the mounting plate 130 and the other end fixed to the limiting block 132.

[0033] Mounting plate 130 is fixed to wall panel 10. Mounting plate 130 extends to turntable 11 and forms a bent portion 131 on the side of turntable 11 away from wall panel 10. Mounting plate 130 has a puncture port 130a at the upper end of the outer peripheral wall of turntable 11. The puncture port 130a communicates with the cavity 114 of turntable 11. Limiting block 132 is located between the turntable 11 on the side away from wall panel 10 and the bent portion 131 of mounting plate 130. Limiting block 132 is connected to the bent portion 131 of mounting plate 130. A groove 111 is formed on the turntable 11 at the position of limiting block 132.

[0034] Due to the setting of the groove 111, the accommodating cavity 110 forms a semi-closed structure at the groove 111 position. Under natural conditions, under the compression force of the spring, the limiting block 132 and the groove 111 form a limiting space. This limiting space can be understood as the upper part of the accommodating cavity 110 near the outer peripheral wall of the turntable 11. The inner diameter of this limiting space in the direction perpendicular to the turntable 11 is smaller than the inner diameter in the direction parallel to the turntable 11. That is, the cross section of this limiting space forms a long strip in the radial direction of the turntable 11, which is adapted to the shape of the sampling tube 20. The limiting block 132 can restrict the sampling tube 20 within this limiting space.

[0035] When the sampling tube 20 rotates to the puncture position via the turntable 11, the spring located between the mounting plate 130 and the limiting block 132 will continuously generate a compressive force on the cap of the sampling tube 20, so that the sampling tube 20 is stable in the puncture position without shaking. The end face of the mounting plate 130 facing the accommodating cavity 110 forms a puncture port 130a, which is connected to the accommodating cavity 110, so that the puncture needle can be inserted into the sampling tube 20 in the accommodating cavity 110 through the puncture port 130a to perform puncture sampling operation.

[0036] The sample unloading assembly is located on the outer periphery of the turntable 11 and below the first retaining ring 112. The first retaining ring 112, the sample unloading assembly, and the second retaining ring 113 form a ring structure, which blocks the outer peripheral wall of the turntable 11 to prevent the sampling tube 20 inside the turntable 11 from sliding out of the turntable 11.

[0037] Specifically, refer to Figure 3 As shown, the sample unloading assembly is located at the bottom of the turntable 11, and includes a base 123. The base 123 is fixed to the wall panel 10. A slide rail 121 and a motor 120 are fixed on the base 123. A slider is adapted on the slide rail 121. The motor 120 is connected to the slider. The sliding door 122 is fixed on the slider or is integrated with the slider. When the motor 120 rotates, it drives the sliding door 122 to move on the slide rail 121. The direction in which the sliding door 122 moves along the slide rail 121 is perpendicular to the surface of the turntable 11. The sliding door 122 corresponds to the opening 114 of the receiving cavity 110 at the bottom of the turntable 11.

[0038] In this way, when the sliding door 122 moves, it can block the opening 114 of the sample unloading cavity 110 of the turntable 11 or move away from the opening 114. In the non-unloading state, the sliding door 122 blocks the opening 114 of the cavity 110; when unloading is required, the sliding door 122 moves away from the opening 114 of the cavity 110. At this time, the opening 114 is unobstructed, and the sampling tube 20 in the opening 114 can slide out from the opening 114 by gravity. The area below this unloading position corresponds to the waste tube compartment. After the sampling tube 20 slides out, it naturally falls into the waste tube compartment.

[0039] On the other hand, the sample processing device is also equipped with several detection components. Depending on their location, the detection components include a sample injection detection component 141, a sample unloading detection component 142, and a sample positioning component 143.

[0040] The sample injection detection component 141 is fixed on the wall plate 10 and located at the upper end of the cavity 114 of the turntable 11 receiving cavity 110 closest to the sample injection port 115. It is used to detect whether the sampling tube 20 is injected into the correct position and whether the sampling tube 20 exceeds the specified length.

[0041] The sample unloading detection component 142 is mounted on the base 123 of the sample unloading component. The base 123 is fixed on the wall plate 10 and located at the upper end of the cavity 114 closest to the sample unloading position accommodating cavity 110. It is used to detect whether the sampling tube 20 has been unloaded.

[0042] The sample positioning component 143 is located at the upper end of the cavity opening 114 of the bottommost accommodating cavity 110 of the turntable 11 and is fixed on the wall plate 10 for accurate positioning of the turntable 11.

[0043] The detection component can specifically be an optocoupler 142b or a light sensor. For example... Figure 3 As shown, taking the sample unloading detection component 142 as an example, an optical coupler plate 142a is provided on the base 123, and an optical coupler 142b is provided on the optical coupler plate 142a. An optical coupler baffle 142c is connected to the moving door 122 of the sample unloading component, so that the optical coupler baffle 142c can move with the moving door 122. When the moving door 122 blocks the cavity opening 114 of the receiving cavity 110 of the sample unloading position, the optical coupler baffle 142b is located inside the optical coupler 142b. When the moving door 122 is moved away, exposing the cavity opening 114 of the receiving cavity 110 for sample unloading, the optical coupler baffle 142c moves with the moving door 122 and is removed from the optical coupler 142b. At this time, the optical coupler 142b sends a signal to the controller, indicating that the sample unloading is complete. The detection components in other positions are executed in a similar manner and will not be described in detail.

[0044] The sample processing device also includes a controller, which is electrically connected to the motor 118 of the detection component and the turntable component, the motor 120 of the sample unloading component, the puncture positioning component, etc., to automatically control, detect, and puncture the entire sample processing device, thereby automating the operation and improving operational efficiency and response accuracy.

[0045] In summary, the sample processing device provided in this application embodiment allows the sampling tube 20 to be inserted through the inlet 115 of the first retaining ring 112 during sample injection, passing through the cavity 114 of the turntable 11 to reach the receiving cavity 110. The turntable 11 is rotated by the motor 118 of the turntable assembly to mix the sample in the sampling tube 20. Since the unloading assembly, the first retaining ring 112, and the second retaining ring 113 form a ring structure surrounding the outer peripheral wall of the turntable 11, blocking the cavity 114, the sampling tube 20 will not slide down under the action of gravity and centrifugal force. The turntable 11 drives the sampling tube 20 to rotate and mix. After rotating several times, the sampling tube 20 reaches the puncture position. The limiting block 132 of the puncture positioning assembly stabilizes the sampling tube 20 in the set position. The puncture needle passes through the puncture port 130a on the mounting plate 130 to puncture the sampling tube 20 for sampling.

[0046] During sample unloading, motor 118 drives turntable 11 to rotate, and sampling tube 20 reaches the unloading position. Motor 120 of the unloading assembly drives slider and movable door 122 fixed on slider, causing movable door 122 to move away from turntable 11 along the direction perpendicular to the turntable 11. The cavity 114 at the unloading position is not blocked by movable door 122, and sampling tube 20 slides naturally from the receiving cavity 110 into the waste tube compartment by gravity. The sample processing device of this application can simultaneously perform sample injection, puncture, and shaking steps while unloading, greatly improving sample processing efficiency. The high integration is achieved through the stacked design of multiple receiving cavities 110 on turntable 11. The turntable assembly completes all sample preprocessing processes (including sample injection, transportation, rotation and shaking, puncture sampling, and unloading) with a simplified structure and drive, while meeting the limited design space requirements.

[0047] The sample processing device provided in the above-described embodiments of this application realizes the functions of sample injection, transportation, mixing, buffering, and unloading of the sampling tube 20, resulting in a simpler process. Through the cooperation of the turntable 11 and the retaining ring, the requirements for sample injection from the outside and rotation of the test tube from the inside can be met, making the mechanism more flexible and space-saving. Simultaneously, motion stability is improved. Stable movement of the device is also achieved through precise motor 118 drive and limit block 132. The sample processing device provided in this embodiment of the application ensures stable operation while improving the reliability and efficiency of sample processing; in space-constrained situations, it realizes all functions of the entire sample processing process, significantly improving the performance of the immunoassay analyzer and meeting a wider range of application needs.

[0048] The above description is merely an embodiment of this application and is not intended to limit the scope of protection of this application. Various modifications and variations can be made to this application by those skilled in the art. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of this application should be included within the scope of protection of this application.

Claims

1. A sample processing device, characterized by, The application relates to a wallboard-based sample collection device, which comprises a rotating disc assembly, a puncture positioning assembly and a sample unloading assembly. The rotating disc assembly comprises a motor and a shaft connected with the motor, and the shaft is connected with the rotating disc.

2. The sample processing device of claim 1, wherein, The rotating disc assembly further comprises a first baffle ring and a second baffle ring, which are oppositely arranged and enclosed on the outer wall of the rotating disc together with the sample unloading assembly to shield the cavity mouth of the accommodating cavity.

3. The sample processing device of claim 2, wherein, The first baffle ring is provided with a sample inlet, which is communicated with the accommodating cavity close to the sample inlet.

4. The sample processing device of claim 3, wherein, The puncture positioning assembly comprises a mounting plate fixed on the wallboard and a limiting block fixed with the mounting plate.

5. The sample processing device of claim 1, wherein, The end surface of the mounting plate facing the accommodating cavity forms a puncture port, which is communicated with the accommodating cavity.

6. The sample processing device of claim 5, wherein, The sample unloading assembly comprises a base fixed on the wallboard, a slide rail and a motor arranged on the base, a sliding block connected with the motor, a moving door arranged on the sliding block to move along the slide rail, and the direction of the moving door along the slide rail is perpendicular to the disc surface of the rotating disc.

7. The sample processing device of claim 1, wherein, The detection assembly is arranged in the accommodating cavity close to the sample inlet to detect whether the sample tube is in place, in the accommodating cavity close to the sample unloading assembly to detect whether the sample tube is unloaded, and in the accommodating cavity at the bottom of the rotating disc to detect whether the rotating disc is accurately positioned.

8. The sample processing device of any one of claims 1 to 7, wherein, The detection assembly comprises an optical coupling or an optical sensor.

9. The sample processing device of claim 8, wherein, The application further comprises a controller electrically connected with the detection assembly, the rotating disc assembly, the sample unloading assembly and the puncture positioning assembly.

10. The sample processing device of claim 8, wherein, ​