Low-pressure low-oxygen culture device for small animals

Abstract

The utility model provides a low-pressure low-oxygen culture device for small animals, which relates to the technical field of medical experiment devices and comprises a culture box and a gas control device. The gas control device comprises a monitoring assembly and gas control equipment, the monitoring assembly is arranged in the incubator and can monitor the air pressure and the oxygen partial pressure in the incubator in real time, and the gas control equipment is connected with the incubator through a pipeline. The air pressure and the oxygen partial pressure in the culture box can be adjusted in an air exhaust or air inflation manner; through the gas control device with the monitoring assembly and the gas control equipment, the internal environment of the incubator can be adjusted to a low-pressure low-oxygen environment, so that a low-pressure low-oxygen experiment is realized, the experiment effect is remarkable, the use and the operation are convenient, the structure is simple, and the cost is low; the device can keep the pressure stable for a long time, and can be used for simulating chronic low-pressure low-oxygen research of plateau life.

Description

Technical Field

[0001] This utility model relates to the field of medical experimental device technology, specifically to a low-pressure, low-oxygen culture device for small animals. Background Technology

[0002] The small animal hypoxia experiment is an experiment that studies the physiological responses of small animals by simulating a low-pressure, low-oxygen environment. The subjects are mostly small and medium-sized animals such as mice and rabbits. These animals are placed in a low-pressure, low-oxygen environment to observe and analyze the effects of the low-pressure, low-oxygen environment on their physiological functions.

[0003] Existing low-pressure and low-oxygen chambers for low-pressure and low-oxygen experiments are bulky, complex in structure, expensive, and cumbersome to operate, making them unsuitable for ordinary users. Therefore, a simple and easy-to-use low-pressure and low-oxygen culture device for small animals is urgently needed. Utility Model Content

[0004] The purpose of this utility model is to provide a low-pressure, low-oxygen culture device for small animals to solve the aforementioned technical problems in the prior art; the preferred technical solutions among the various technical solutions provided by this utility model can produce many technical effects, as detailed below.

[0005] To achieve the above objectives, the present invention provides the following technical solution:

[0006] This utility model provides a low-pressure, low-oxygen culture device for small animals, comprising an incubator and a gas control device, wherein: the incubator is provided with a placement position for placing animal cages; the gas control device includes a monitoring component and a gas control device, the monitoring component is disposed in the incubator and can monitor the gas pressure and oxygen partial pressure in the incubator in real time, and the gas control device is connected to the incubator through a pipeline and can adjust the gas pressure and oxygen partial pressure in the incubator by evacuating or inflating the gas.

[0007] Preferably, the incubator includes a box body and a support frame disposed within the box body, and the support frame is provided with at least one placement position.

[0008] Preferably, the enclosure includes a front panel, a door frame is provided on the front panel, and a door is provided on the door frame; the front panel is a transparent panel; and the door is a transparent door.

[0009] Preferably, the support frame has multiple placement positions arranged in a vertical hierarchy inside.

[0010] Preferably, the support frame includes two rectangular frames symmetrically arranged in the front-back direction, and a horizontal support frame is connected between the two rectangular frames, with the placement position formed below and above the horizontal support frame.

[0011] Preferably, the number of horizontal support frames is set to two, and the two horizontal support frames are symmetrically arranged in the support frame in the left-right direction relative to the door frame.

[0012] Preferably, a handle is provided on the left side wall and / or right side wall of the housing.

[0013] Preferably, the monitoring component includes an oxygen partial pressure sensor and a gas pressure sensor, both of which are disposed inside the incubator; the monitoring component also includes a humidity sensor and a temperature sensor, both of which are disposed inside the incubator.

[0014] Preferably, the housing is provided with an inlet quick-connect connector and an outlet quick-connect connector on the side near the gas control device. The height of the inlet quick-connect connector is greater than the height of the outlet quick-connect connector. The inlet quick-connect connector and the outlet quick-connect connector are used to connect the inlet pipe and the outlet pipe, respectively. A filter device is provided on the gas control device and connected to the inlet pipe and / or the outlet pipe. A wire harness connector is provided on the side of the housing near the gas control device.

[0015] Preferably, the gas control device is configured as an air extraction device, which adjusts the gas pressure and oxygen partial pressure inside the incubator by extracting air.

[0016] The low-pressure, low-oxygen culture device for small animals provided by this utility model has at least the following beneficial effects:

[0017] The low-pressure, low-oxygen culture device for small animals includes an incubator and a gas control device. The incubator provides space for low-pressure, low-oxygen experiments on small animals, while the gas control device is used to control the gas pressure and oxygen partial pressure inside the incubator, enabling it to form a low-pressure, low-oxygen environment.

[0018] The incubator is equipped with a placement area, where the animal cage and the animals inside can be placed directly during actual use.

[0019] The gas control device includes a monitoring component and a gas control device. The monitoring component is installed inside the incubator, and the gas control device is connected to the incubator through a pipeline. Before the low-pressure, low-oxygen experiment, the gas control device adjusts the gas pressure and oxygen in the incubator to a low-pressure, low-oxygen state by evacuating or filling the incubator. Before the low-pressure, low-oxygen experiment, the gas control device evacuates or fills the incubator at a preset frequency to achieve air circulation and maintain the target gas pressure, oxygen partial pressure, temperature, and air humidity. During this process, since small animals are kept in the incubator, their breathing and excretion will make the air turbid, and the carbon dioxide concentration and humidity will increase. By intermittently evacuating or filling the incubator, the stable state of the environment inside the incubator can be effectively maintained.

[0020] This invention utilizes a gas control device with monitoring components and gas control equipment to adjust the internal environment of the incubator to a low-pressure, low-oxygen environment, thereby achieving low-pressure, low-oxygen experiments. This not only results in significant experimental effects but also provides convenient operation, simple structure, and low cost.

[0021] This invention can maintain stable pressure for a long time and can be used for research on chronic low pressure and low oxygen to simulate high-altitude life. Attached Figure Description

[0022] To more clearly illustrate the technical solutions in the embodiments of this utility model or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of this utility model. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0023] Figure 1 This is a schematic diagram of the structure of this utility model;

[0024] Figure 2 This is a structural schematic diagram of the incubator (excluding the door) of this utility model;

[0025] Figure 3 This is a structural schematic diagram of the incubator (excluding the front panel) of this utility model;

[0026] Figure 4 This is a schematic diagram of the support frame of this utility model;

[0027] Figure 5 This is a structural block diagram of one embodiment of the air extraction device and monitoring component of this utility model;

[0028] Figure 6 This is a structural block diagram of another embodiment of the air extraction device and monitoring component of this utility model;

[0029] Figure 7 This is a rear view schematic diagram of the air extraction device of this utility model.

[0030] Figure Labels

[0031] 1. Incubator; 11. Chamber; 111. Front panel; 112. Door frame; 113. Handle; 114. Inlet quick-connect connector; 115. Outlet quick-connect connector; 116. Wiring harness connector; 117. Mounting frame; 12. Support frame; 121. Placement position; 122. Rectangular frame; 1221. Rectangular border; 1222. Column; 1223. Reinforcing rod; 123. Support beam; 124. Horizontal support frame; 2. Gas control device; 21. Vacuuming device; 22. Monitoring components; 221. Oxygen partial pressure sensor; 222. Gas pressure sensor; 223. Temperature sensor; 224. Humidity sensor; 23. Filter device; 3. Alarm device. Detailed Implementation

[0032] To make the objectives, technical solutions, and advantages of this utility model clearer, the technical solutions of this utility model will be described in detail below. Obviously, the described embodiments are only a part of the embodiments of this utility model, and not all of them. Based on the embodiments of this utility model, all other implementation methods obtained by those skilled in the art without creative effort are within the scope of protection of this utility model.

[0033] Example 1:

[0034] This invention provides a low-pressure, low-oxygen culture device for small animals, referenced... Figures 1 to 7 As shown, the low-pressure, low-oxygen culture device for small animals includes an incubator 1 and a gas control device 2.

[0035] The incubator 1 is equipped with a placement space 121, which is used to place animal cages for culturing small animals.

[0036] The gas control device 2 includes a monitoring component 22 and a gas control device. The monitoring component 22 is installed inside the incubator 1, and the gas control device is connected to the incubator 1 through a pipeline.

[0037] During the low-pressure, low-oxygen experiment, the animal cage is placed on placement position 121, and the gas control device is activated. The gas control device adjusts the air pressure and oxygen partial pressure inside the incubator 1 by pumping or filling air at a preset frequency, thereby creating a low-pressure, low-oxygen environment. During the experiment, the breathing and snoring of the small animals will pollute the air and increase the carbon dioxide concentration, thus affecting the air pressure and oxygen partial pressure. The monitoring component 22 monitors the air pressure and oxygen partial pressure inside the incubator 1 in real time. It works with the gas control device to maintain the air pressure and oxygen partial pressure inside the incubator 1 at a constant state, thereby maintaining a low-pressure, low-oxygen environment for a long time.

[0038] This invention, through a gas control device with a monitoring component 22 and a gas control device, can adjust the internal environment of the incubator 1 to a low-pressure, low-oxygen environment, thereby realizing low-pressure, low-oxygen experiments. Not only are the experimental results significant, but the operation is also convenient. At the same time, the overall structure is simple and the cost is low.

[0039] Example 2:

[0040] Example 2 is based on Example 1:

[0041] like Figures 1 to 7 As shown, the incubator 1 includes a box body 11 and a support frame 12. The support frame 12 is disposed inside the box body 11, and at least one placement position 121 is provided on the support frame 12.

[0042] The support frame 12 is a load-bearing component, and the box 11 is a sealing component, which can form a relatively closed internal environment, making it easy to maintain low pressure and low oxygen.

[0043] As an optional implementation, the box 11 has a cubic structure, including a front panel 111, a rear panel, a left panel, a right panel, a top panel, and a bottom panel. A door frame 112 is provided on the front panel 111, and a door is provided at the position of the door frame 112 that can be opened and closed.

[0044] Specifically, the cage door is hinged and can be flipped on the door frame 112. In actual use, the animal cage can be put in and taken out by opening the cage door.

[0045] The front panel 111 is a transparent panel; the cabinet door is a transparent door, and both the front panel 111 and the cabinet door can be made of transparent plastic material.

[0046] With this setup, users can directly observe the physiological functions of small animals in low-pressure, low-temperature environments.

[0047] As an optional implementation, the support frame 12 has multiple placement positions 121 arranged vertically inside.

[0048] The multiple placement positions 121 can accommodate multiple animal cages, thereby enabling low-pressure and low-oxygen experiments with multiple experimental groups of the same type or multiple experimental groups of different types (different small animals).

[0049] As an optional implementation, the support frame 12 includes two rectangular frames 122 symmetrically arranged in the front-back direction, and a horizontal support frame 124 is connected between the two rectangular frames 122. The horizontal support frame 124 is a rectangular support frame, thus forming a double-layer structure. Placement positions 121 are formed below and above the horizontal support frame 124.

[0050] As an optional implementation, the number of horizontal support frames 124 is set to two. The two horizontal support frames 124 are symmetrically arranged in the support frame 12 in the left and right directions relative to the door frame 112, which can form two double-layer structures that are symmetrical in the left and right directions.

[0051] The rectangular frame 122 includes a rectangular border 1221. Support beams 123 are horizontally connected between two rectangular frames 122, and all support beams 123 are evenly distributed along the edge of the rectangular border 1221.

[0052] Two vertical columns 1222 are set in the middle of the rectangular frame 1221, and a horizontal support frame 124 is connected to the outside of the corresponding column 1222. An inclined reinforcing rod 1223 is provided between the rectangular frame 1221 and the column 1222.

[0053] In practical applications, multiple horizontal support frames 124 can be set along the vertical direction to form a multi-layer structure, and the specific number of layers can be set according to actual needs.

[0054] Furthermore, the inner wall of the support frame 12 may also be provided with an inner cladding panel.

[0055] As an optional implementation, a handle 113 is provided on the left side wall and / or right side wall of the housing 11.

[0056] The handle 113 facilitates the movement of the incubator 1.

[0057] Specifically, a handle 113 is provided on the left side wall of the box 11, and a fixing frame 117 is provided on the right side wall. The fixing frame 117 is a stand, which can reduce the distance between the incubator 1 and the gas control device, making the overall structure more compact. On the other hand, it can also be used for gripping without affecting the movement of the incubator 1.

[0058] As an optional implementation, the monitoring component 22 includes an oxygen partial pressure sensor 221 and a gas pressure sensor 222, both of which are located inside the incubator 1 and are positioned away from the inlet quick connector 114 and the outlet quick connector 115.

[0059] Optionally, the oxygen partial pressure sensor 221 adopts an OOM202 type oxygen concentration sensor, and the pressure sensor 222 adopts an XGZP6847 type pressure sensor.

[0060] As an optional implementation, the monitoring component 22 also includes a humidity sensor 224 and a temperature sensor 223, both of which are disposed inside the incubator 1 and located away from the inlet quick connector 114 and the outlet quick connector 115.

[0061] Furthermore, the small animal low-pressure low-oxygen culture device also includes an alarm device 3, which is installed on the wall of the box 11. The alarm device 3 can be an audible and visual alarm device, which can issue an alarm when the air pressure, oxygen partial pressure, temperature or humidity is abnormal. This is existing technology and will not be described in detail here.

[0062] As an optional implementation, the housing 11 is provided with an inlet quick connector 114 and an outlet quick connector 115 on the side near the gas control device. The height of the inlet quick connector 114 is greater than the height of the outlet quick connector 115, forming an airflow pattern of top inlet and bottom outlet.

[0063] The quick-connect fitting 114 for air intake and the quick-connect fitting 115 for air outlet are used to connect the air intake pipe and the air outlet pipe, respectively. A filter device 23 is provided on the gas control equipment in connection with the air intake pipe and / or the air outlet pipe.

[0064] Preferably, the gas control device is provided with two filter devices 23, which are connected to the inlet quick connector 114 and the outlet quick connector 115 respectively through the inlet pipe and the outlet pipe; further, the filter device 23 is an air filter, specifically a ZFC series, model 100-06B.

[0065] A wire harness connector 116 is provided on the side of the housing 11 near the gas control device to facilitate wire harness laying.

[0066] As an optional implementation, the gas control device is configured as an air extraction device 21, which controls the gas pressure and oxygen partial pressure inside the incubator 1 by air extraction.

[0067] During the low-pressure, low-oxygen experiment, as the small animals breathe, the carbon dioxide produced will affect the oxygen partial pressure and gas pressure inside the incubator 1. At this time, the gas inside the incubator 1 is extracted by the air extraction device 21, and at the same time, fresh air enters the incubator 1, thereby ensuring the oxygen partial pressure and gas pressure inside the incubator 1.

[0068] In the description of this application, it should be understood that the terms "upper", "lower", "inner", "outer", "front", "rear", "left", "right", "top", "bottom", etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings. They are only for the convenience of describing this application and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on this application.

[0069] Furthermore, in the description of this application, the terms "multiple" and "several" mean at least two, such as two, three, etc., unless otherwise explicitly specified.

[0070] In this application, unless otherwise expressly specified and limited, the terms "installation," "connection," "linking," "fixing," etc., should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral part; they can refer to a direct connection or an indirect connection through an intermediate medium; they can refer to the internal communication of two components or the interaction between two components, unless otherwise expressly limited. Those skilled in the art can understand the specific meaning of the above terms in this application according to the specific circumstances.

[0071] The above description is merely a specific embodiment of this utility model, but the protection scope of this utility model is not limited thereto. Any variations or substitutions that can be easily conceived by those skilled in the art within the technical scope disclosed in this utility model should be included within the protection scope of this utility model. Therefore, the protection scope of this utility model should be determined by the protection scope of the claims.

Claims

1. A low-pressure, low-oxygen culture device for small animals, characterized in that, Includes an incubator and a gas control device, wherein: The incubator is equipped with a placement area for placing animal cages; The gas control device includes a monitoring component and a gas control device. The monitoring component is installed inside the incubator and can monitor the gas pressure and oxygen partial pressure inside the incubator in real time. The gas control device is connected to the incubator through a pipeline and can adjust the gas pressure and oxygen partial pressure inside the incubator by evacuating or filling the incubator.

2. The low-pressure, low-oxygen culture device for small animals according to claim 1, characterized in that, The incubator includes a box body and a support frame disposed within the box body, and at least one placement position is provided on the support frame.

3. The low-pressure, low-oxygen culture device for small animals according to claim 2, characterized in that, The enclosure includes a front panel, a door frame is provided on the front panel, and a door is provided on the door frame that can be opened and closed. The front panel is a transparent panel; The door of the box is a transparent door.

4. The low-pressure, low-oxygen culture device for small animals according to claim 2, characterized in that, The support frame has multiple placement positions arranged in a vertical hierarchy inside.

5. The low-pressure, low-oxygen culture device for small animals according to claim 3, characterized in that, The support frame includes two rectangular frames arranged symmetrically in the front-back direction, and a horizontal support frame is connected between the two rectangular frames. The placement position is formed below and above the horizontal support frame.

6. The low-pressure, low-oxygen culture device for small animals according to claim 5, characterized in that, The number of horizontal support frames is set to two, and the two horizontal support frames are symmetrically arranged in the support frame in the left-right direction relative to the door frame.

7. The low-pressure, low-oxygen culture device for small animals according to claim 2, characterized in that, The box is provided with handles on the left and / or right side walls.

8. The low-pressure, low-oxygen culture device for small animals according to claim 1, characterized in that, The monitoring components include an oxygen partial pressure sensor and a gas pressure sensor, both of which are located inside the incubator. The monitoring component also includes a humidity sensor and a temperature sensor, both of which are located inside the incubator.

9. The low-pressure, low-oxygen culture device for small animals according to claim 2, characterized in that, The housing is provided with an inlet quick connector and an outlet quick connector on the side near the gas control device. The height of the inlet quick connector is greater than the height of the outlet quick connector. The inlet quick connector and the outlet quick connector are used to connect the inlet pipe and the outlet pipe, respectively. A filter device is provided on the gas control device in connection with the inlet pipe and / or the outlet pipe. A wire harness connector is provided on the side of the housing closest to the gas control device.

10. The low-pressure, low-oxygen culture device for small animals according to claim 1, characterized in that, The gas control device is configured as an air extraction device, which adjusts the gas pressure and oxygen partial pressure inside the incubator by extracting air.

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