Auxiliary experimental mouse tail vein injection device

Abstract

The utility model discloses an auxiliary laboratory mouse tail vein injection device which comprises a laboratory mouse fixing mechanism and an injection mechanism, and the laboratory mouse fixing mechanism is used for fixing a laboratory mouse; the laboratory mouse fixing mechanism comprises a containing pipe assembly, the containing pipe assembly is used for containing a laboratory mouse, the front end and the rear end of the containing pipe assembly are detachably connected with a head end cover and a tail end cover through connecting pieces respectively, a plurality of air holes are formed in the head end cover, and an opening allowing the mouse tail to stretch out is formed in the tail end cover; the connecting piece comprises a side support, the side support is installed on the side wall of the head end cover and the side wall of the tail end cover, and a clamping hook is rotatably installed on the side support through a shaft. According to the utility model, the experimental mouse fixing mechanism is arranged, so that the tail end cover can be detached, the experimental mouse is placed in the accommodating tube assembly, and then the tail end cover is mounted on the accommodating tube assembly, and the tail of the experimental mouse penetrates through the opening and is exposed outside the accommodating tube assembly, so that injection is facilitated.

Description

Technical Field

[0001] This utility model relates to the field of animal experimental equipment technology, and in particular to an auxiliary device for tail vein injection in experimental mice. Background Technology

[0002] Laboratory mice are among the most commonly used laboratory animals. For various biological experiments, tail vein injection is often necessary. Tail vein injection is a method of directly injecting drugs or other substances into the animal's bloodstream, commonly used for drug administration, sampling, or injecting tracers. However, due to the small size and high mobility of laboratory mice, manually restraining them and performing the injection is not only difficult but also prone to causing injury, thus affecting the experiment.

[0003] A search revealed Chinese patent application CN202420123921.6, which discloses a rat tail vein injection fixation device, comprising a cylindrical container and a cap. A vent tube is connected to the end of the cylindrical container. A shell is symmetrically fixed to the outer edge of the cylindrical container. Insertion holes are formed on the sidewalls of the shells. A locking assembly is slidably disposed at the top of the inner cavity of the shells. Insertion rods are symmetrically fixed to the side of the cap near the cylindrical container. Wedge-shaped grooves are symmetrically formed on the sides of the two sets of insertion rods that are far apart from each other. A through hole is formed at the bottom of the sidewall of the cap, and a fixing plate is fixedly connected to the through hole. Several sets of notches are evenly spaced at both ends of the fixing plate. The injection fixation device in the above-mentioned literature has the following shortcomings: its size is relatively fixed and it cannot be applied to experimental mice of different sizes. Utility Model Content

[0004] The purpose of this invention is to address the shortcomings of existing technologies by proposing an auxiliary experimental rat tail vein injection device.

[0005] To achieve the above objectives, the present invention adopts the following technical solution:

[0006] A device for assisting in tail vein injection in laboratory mice includes a mouse fixation mechanism and an injection mechanism, wherein the mouse fixation mechanism is used to fix the laboratory mouse.

[0007] The experimental mouse fixation mechanism includes: a receiving tube assembly, which is used to receive the experimental mouse. The front end and rear end of the receiving tube assembly are detachably connected to a head end cover and a tail end cover by connectors. The head end cover has multiple air holes, and the tail end cover has an opening for the mouse tail to extend out.

[0008] The connector includes a side support, which is installed on the side wall of the head end cover and the tail end cover. A hook is rotatably mounted on the side support via a shaft. The side of the receiving tube assembly is provided with linearly distributed positioning teeth, which are adapted to the hook. A connecting piece is fixed to one end of the hook, and the shaft of the hook is connected to the side support via a spring.

[0009] As a further embodiment of this utility model: the receiving tube assembly includes a first receiving tube and a second receiving tube, which are connected by an elastic connecting part; the positioning teeth are respectively disposed on the sides of the first receiving tube and the second receiving tube; and side supports are provided on the sides of both the first receiving tube and the second receiving tube.

[0010] A guide rod is fixed on one side support of the first receiving tube, and the guide rod is slidably connected to the inner wall of one side support of the second receiving tube; a threaded knob is rotatably installed on the other side support of the first receiving tube, and the threaded knob is threadedly connected to the inner wall of the other side support of the second receiving tube.

[0011] As a further improvement of this utility model: the experimental mouse fixing mechanism is used in conjunction with a support mechanism; the support mechanism includes a mounting frame, on which a support frame is mounted, a buckle is provided on the top of the support frame, and a side rod adapted to the buckle is installed on the side of the first receiving tube.

[0012] As a further embodiment of this utility model: a slide block is fixed to one side of the outer wall of the support frame, a slide rail is installed on the mounting frame, the slide block is slidably connected to the slide rail, and a threaded rod is rotatably installed in the slide rail, the threaded rod being threadedly connected to the inner wall of the slide block.

[0013] As a further embodiment of this utility model: a toothed rod is installed on the mounting bracket, a sliding frame is movably installed on the toothed rod, and a top plate is fixed to the top of the sliding frame; a fixing member for fixing the sliding frame to the toothed rod is installed on the sliding frame.

[0014] As a further improvement of this utility model: the fixing member includes:

[0015] The tie rod is slidably connected to the inner wall of the sliding frame.

[0016] The toothed block is fixed to one end of the pull rod near the toothed bar. The toothed bar has evenly distributed convex teeth on its side, and the toothed block is adapted to the convex teeth.

[0017] A spring, one end of which is fixed to the sliding frame, and the other end of which is fixed to one end of the pull rod;

[0018] Pull ring, the pull ring is fixed to the outer wall of one end of the pull rod.

[0019] As a further improvement of this utility model: a strip groove is provided on the top plate, and the position of the strip groove is adapted to the opening.

[0020] The beneficial effects of this utility model are as follows:

[0021] 1. This utility model, by setting up a laboratory mouse fixation mechanism, allows the tail end cap to be removed, the laboratory mouse to be placed inside the receiving tube assembly, and then the tail end cap to be installed on the receiving tube assembly, so that the laboratory mouse's tail passes through the opening and is exposed outside the receiving tube assembly for easy injection. In addition, due to the setting of hooks and linearly distributed positioning teeth, the installation position of the head end cap or tail end cap can be adjusted according to needs, thereby adjusting the length of the receiving tube assembly extending into the head end cap or tail end cap, achieving the purpose of adjusting the overall effective length of the laboratory mouse fixation mechanism. It is suitable for laboratory mice of different sizes, and the use of hooks and positioning teeth in combination can better avoid the laboratory mouse's hands compared to screwing and other methods, thus improving reliability.

[0022] 2. By setting up an elastic connecting part, a threaded knob and other structures, this utility model can adjust the distance between the first and second receiving tubes by turning the threaded knob, thereby adapting to experimental mice of different sizes and improving its practicality.

[0023] 3. By setting up structures such as side rods and support frames, this utility model can lock the side rods into the buckles of the support frames to support and fix the experimental mouse fixing mechanism, so as to facilitate operation; by setting up structures such as slide rails and threaded screw rods, the height of the slide can be adjusted by turning the threaded screw rod, thereby adjusting the height of the support frame, which improves practicality.

[0024] 4. This utility model, by setting a top plate with a strip groove, can place the rat tail in the strip groove and press it into position for easy injection operation, thus improving practicality; by setting a fixing component, the pull rod can be pulled to both sides, causing the toothed block to disengage from the toothed bar's convex teeth. After adjusting the height of the top plate as needed, the toothed block and the convex teeth are engaged under the action of spring rebound force, thereby fixing the sliding frame. Attached Figure Description

[0025] Figure 1 This is a schematic diagram of the structure of an auxiliary experimental rat tail vein injection device proposed in this utility model;

[0026] Figure 2 This is a schematic diagram of the structure of an auxiliary experimental rat tail vein injection device proposed in this utility model from another angle;

[0027] Figure 3 This is a schematic diagram of the experimental mouse fixation mechanism of the auxiliary experimental mouse tail vein injection device proposed in this utility model, detached from the support frame.

[0028] Figure 4 This is a cross-sectional schematic diagram of the sliding frame of an auxiliary experimental rat tail vein injection device proposed in this utility model;

[0029] Figure 5 This is a schematic diagram of the structure of the experimental mouse fixation mechanism of the auxiliary experimental mouse tail vein injection device proposed in this utility model;

[0030] Figure 6 This is a schematic diagram showing the disassembled structure of the experimental mouse fixation mechanism of the auxiliary experimental mouse tail vein injection device proposed in this utility model.

[0031] In the diagram: 1-Mounting bracket, 2-Tooth bar, 3-Sliding bracket, 4-Top plate, 5-Tail end cover, 6-Second receiving tube, 7-Elastic connection part, 8-First receiving tube, 9-Threaded screw rod, 10-Slide rail, 11-Head end cover, 12-Support bracket, 13-Air hole, 14-Side rod, 15-Opening, 16-Strip groove, 17-Tooth block, 18-Spring, 19-Pull ring, 20-Pull rod, 21-Side bracket, 22-Threaded knob, 23-Connecting piece, 24-Hook, 25-Guide rod, 26-Positioning tooth, 27-Side support. Detailed Implementation

[0032] The technical solution of this utility model will be further described in detail below with reference to specific embodiments.

[0033] The embodiments of this utility model are described in detail below. Examples of these embodiments are shown in the accompanying drawings, wherein the same or similar reference numerals denote the same or similar elements or elements having the same or similar functions throughout. The embodiments described below with reference to the accompanying drawings are exemplary and are only used to explain this utility model, and should not be construed as limiting this utility model.

[0034] Example 1

[0035] A device for assisting in tail vein injection in laboratory mice, such as Figure 1-6 As shown, it includes a mouse restraint mechanism and an injection mechanism. The injection mechanism is not shown in the figure, but can be a commonly used syringe or other similar device, which will not be described in detail here. The mouse restraint mechanism is used to restrain the experimental mouse.

[0036] The experimental mouse fixation mechanism includes: a receiving tube assembly for accommodating the experimental mouse; a head end cover 11 and a tail end cover 5 are detachably connected to the front and rear ends of the receiving tube assembly via connectors; the head end cover 11 has multiple air holes 13, and the tail end cover 5 has an opening 15 for the mouse tail to extend out; the connectors include side supports 27, which are mounted on the side walls of the head end cover 11 and the tail end cover 5; hooks 24 are rotatably mounted on the side supports 27 via shafts; linearly distributed positioning teeth 26 are provided on the side of the receiving tube assembly, which are adapted to the hooks 24; a connecting piece 23 is fixed to one end of the hooks 24; the shaft of the hooks 24 is connected to the side supports 27 via a spring; based on the force of the spring, the hooks 24 are engaged with the positioning teeth 26, thereby fixing the head end cover 11 and the tail end cover 5.

[0037] By setting up a mouse fixation mechanism, the tail end cap 5 can be removed, the mouse can be placed inside the receiving tube assembly, and then the tail end cap 5 can be installed on the receiving tube assembly, so that the mouse's tail passes through the opening 15 and is exposed to the outside of the receiving tube assembly for easy injection.

[0038] To facilitate adjustment of the dimensions of the receiving tube assembly; such as Figure 5 , Figure 6 As shown, the receiving tube assembly includes a first receiving tube 8 and a second receiving tube 6, which are connected by an elastic connecting part 7; the positioning teeth 26 are respectively disposed on the sides of the first receiving tube 8 and the second receiving tube 6; and side brackets 21 are provided on the sides of both the first receiving tube 8 and the second receiving tube 6.

[0039] A guide rod 25 is fixed on one side bracket 21 of the first receiving tube 8, and the guide rod 25 is slidably connected to the inner wall of one side bracket 21 of the second receiving tube 6; a threaded knob 22 is rotatably installed on the other side bracket 21 of the first receiving tube 8, and the threaded knob 22 is threadedly connected to the inner wall of the other side bracket 21 of the second receiving tube 6.

[0040] By setting up structures such as the elastic connection part 7 and the threaded knob 22, the distance between the first receiving tube 8 and the second receiving tube 6 can be adjusted by turning the threaded knob 22, thereby adapting to experimental mice of different sizes and improving practicality.

[0041] For ease of operation; such as Figure 1 As shown, the experimental mouse fixing mechanism is used in conjunction with a support mechanism; the support mechanism includes a mounting frame 1, a support frame 12 is mounted on the mounting frame 1, a buckle is provided on the top of the support frame 12, and a side rod 14 adapted to the buckle is mounted on the side of the first receiving tube 8.

[0042] By setting up structures such as side rod 14 and support frame 12, the side rod 14 can be snapped into the buckle of support frame 12 to support and fix the experimental mouse fixation mechanism, so as to facilitate operation.

[0043] To facilitate adjustment of the structural position; such as Figure 1 , Figure 3 As shown, a slide block is fixed on one side of the outer wall of the support frame 12, and a slide rail 10 is installed on the mounting frame 1. The slide block is slidably connected to the slide rail 10. A threaded rod 9 is rotatably installed in the slide rail 10. The threaded rod 9 is threadedly connected to the inner wall of the slide block.

[0044] By setting up structures such as slide rail 10 and threaded rod 9, the height of the slide can be adjusted by turning the threaded rod 9, thereby adjusting the height of the support frame 12 and improving practicality.

[0045] For ease of operation; such as Figure 1 , Figure 3 , Figure 4 As shown, a toothed rod 2 is mounted on the mounting frame 1, and a sliding frame 3 is movably mounted on the toothed rod 2. A top plate 4 is fixed to the top of the sliding frame 3. A fixing member for fixing the sliding frame 3 to the toothed rod 2 is mounted on the sliding frame 3.

[0046] For ease of fixing; such as Figure 4 As shown, the fastener includes:

[0047] Pull rod 20 is slidably connected to the inner wall of sliding frame 3;

[0048] Tooth block 17 is fixed to one end of pull rod 20 near tooth bar 2. Tooth bar 2 has evenly distributed convex teeth on its side, and tooth block 17 is adapted to the convex teeth.

[0049] Spring 18, one end of spring 18 is fixed to sliding frame 3, and the other end of spring 18 is fixed to one end of pull rod 20;

[0050] Pull ring 19 is fixed to the outer wall of one end of pull rod 20;

[0051] By setting a fixing component, the pull rod 20 can be pulled to both sides, so that the toothed block 17 disengages from the toothed bar 2. After adjusting the height of the top plate 4 as needed, the toothed block 17 engages with the toothed bar under the action of the spring 18, thereby fixing the sliding frame 3.

[0052] For ease of use; such as Figure 4 As shown, a strip groove 16 is provided on the top plate 4, and the position of the strip groove 16 is adapted to the opening 15;

[0053] By setting a top plate 4 with a strip groove 16, the rat's tail can be placed in the strip groove 16 and pressed into position to facilitate injection operations, thus improving practicality.

[0054] The above description is only a preferred embodiment of the present utility model, but the protection scope of the present utility model is not limited thereto. Any equivalent substitutions or changes made by those skilled in the art within the technical scope disclosed in the present utility model, based on the technical solution and the inventive concept of the present utility model, should be included within the protection scope of the present utility model.

Claims

1. An auxiliary device for tail vein injection in laboratory mice, characterized in that, It includes a mouse restraint mechanism and an injection mechanism, wherein the mouse restraint mechanism is used to restrain the experimental mouse; The experimental mouse fixation mechanism includes: a receiving tube assembly, which is used to receive the experimental mouse. The front end and the rear end of the receiving tube assembly are detachably connected to a head end cover (11) and a tail end cover (5) respectively via connectors. The head end cover (11) has multiple air holes (13), and the tail end cover (5) has an opening (15) for the mouse tail to extend out. The connector includes a side support (27), which is installed on the side wall of the head end cover (11) and the tail end cover (5). A hook (24) is rotatably mounted on the side support (27) via a shaft. Linearly distributed positioning teeth (26) are provided on the side of the receiving tube assembly. The positioning teeth (26) are adapted to the hook (24). A connecting piece (23) is fixed to one end of the hook (24). The shaft of the hook (24) is connected to the side support (27) via a spring.

2. The auxiliary experimental rat tail vein injection device according to claim 1, characterized in that, The receiving tube assembly includes a first receiving tube (8) and a second receiving tube (6), which are connected by an elastic connecting part (7); the positioning teeth (26) are respectively disposed on the sides of the first receiving tube (8) and the second receiving tube (6); and the sides of the first receiving tube (8) and the second receiving tube (6) are each provided with a side bracket (21). A guide rod (25) is fixed on one side bracket (21) of the first receiving tube (8), and the guide rod (25) is slidably connected to the inner wall of one side bracket (21) of the second receiving tube (6); a threaded knob (22) is rotatably installed on the other side bracket (21) of the first receiving tube (8), and the threaded knob (22) is threadedly connected to the inner wall of the other side bracket (21) of the second receiving tube (6).

3. The auxiliary experimental rat tail vein injection device according to claim 2, characterized in that, The experimental mouse fixing mechanism is used in conjunction with a support mechanism; the support mechanism includes a mounting frame (1), a support frame (12) is mounted on the mounting frame (1), a buckle is provided on the top of the support frame (12), and a side rod (14) adapted to the buckle is installed on the side of the first receiving tube (8).

4. The auxiliary experimental rat tail vein injection device according to claim 3, characterized in that, A slide block is fixed on one side of the outer wall of the support frame (12), and a slide rail (10) is installed on the mounting frame (1). The slide block is slidably connected to the slide rail (10). A threaded rod (9) is rotatably installed inside the slide rail (10). The threaded rod (9) is connected to the inner wall of the slide block by a thread.

5. The auxiliary experimental rat tail vein injection device according to claim 3, characterized in that, A rack (2) is mounted on the mounting bracket (1), and a sliding bracket (3) is movably mounted on the rack (2). A top plate (4) is fixed to the top of the sliding bracket (3). A fastener for fixing the sliding bracket (3) to the rack (2) is mounted on the sliding bracket (3).

6. The auxiliary experimental rat tail vein injection device according to claim 5, characterized in that, The fastener includes: Pull rod (20), pull rod (20) is slidably connected to the inner wall of sliding frame (3); Tooth block (17) is fixed to one end of the pull rod (20) near the toothed rod (2). The toothed rod (2) has evenly distributed protruding teeth on its side. The tooth block (17) is matched with the protruding teeth. Spring (18), one end of spring (18) is fixed to sliding frame (3), and the other end of spring (18) is fixed to one end of pull rod (20); Pull ring (19) is fixed to the outer wall of one end of pull rod (20).

7. The auxiliary experimental rat tail vein injection device according to claim 6, characterized in that, The top plate (4) has a strip groove (16) which is matched with the opening (15).

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