Chenodeoxycholic acid concentration and crystallization tank

Abstract

The utility model relates to the technical field of chenodeoxycholic acid crystal production and processing, and discloses a chenodeoxycholic acid concentration and crystallization tank which comprises a shell, the upper surface of the shell is slidably connected with a top cover, the upper surface of the top cover is provided with a filter assembly, the lower surface of the shell is fixedly connected with a temporary storage cover, and the temporary storage cover is provided with a storage cavity. An inner shell is fixedly connected to the interior of the temporary storage cover, a heating wire is fixedly connected to the outer wall of the inner shell, a first support is fixedly connected to the upper surface of the top cover, and a stirring assembly is arranged on the inner wall of the first support; the stirring assembly comprises a motor, the outer wall of the motor is fixedly connected to the inner wall of the first support, and the output end of the motor is fixedly connected with a rotating shaft. According to the chenodeoxycholic acid crystal stirring device, through the shape design of the square stirring blades, crystals attached to the inner wall of the inner shell can be scraped off, the situation that the finally obtained chenodeoxycholic acid crystals are reduced due to the fact that the crystals are attached to the inner wall of the inner shell is avoided, and the production efficiency of the chenodeoxycholic acid crystals is improved.

Description

Technical Field

[0001] This utility model relates to the field of chenodeoxycholic acid crystal production and processing technology, and in particular to a chenodeoxycholic acid concentration and crystallization tank. Background Technology

[0002] In the pharmaceutical and chemical industries, chenodeoxycholic acid, as an important organic compound, is widely used in the production of drugs for the treatment of gallstones. The chenodeoxycholic acid concentration and crystallization tank is a key piece of equipment for preparing high-purity chenodeoxycholic acid crystals; its performance directly affects product quality and production efficiency, playing a crucial role in the entire production process.

[0003] Currently, common chenodeoxycholic acid concentration and crystallization tanks mainly employ traditional heating evaporation and natural crystallization techniques. The mechanical structure is typically a simple tank equipped with ordinary heating devices, such as a bottom heating plate, which heats and evaporates the solution inside the tank through heat transfer. During crystallization, crystals precipitate naturally due to the solution's natural cooling and changes in the solubility of the solute itself; there is no special auxiliary stirring or structure to promote uniform crystallization.

[0004] However, existing chenodeoxycholic acid concentration and crystallization tanks are usually simple tanks that lack effective stirring and anti-adhesion measures. A large number of crystals easily adhere to the inner wall of the shell. This not only reduces the number of chenodeoxycholic acid crystals collected from the tank, thus reducing production efficiency, but also makes it difficult to clean the attached crystals, increasing the difficulty and cost of subsequent equipment maintenance and affecting the continuity and stability of the entire production process. Utility Model Content

[0005] To overcome the above shortcomings, this utility model provides a chenodeoxycholic acid concentration and crystallization tank, which aims to improve the existing chenodeoxycholic acid concentration and crystallization tanks, which lack effective stirring and anti-adhesion measures, resulting in crystals easily adhering to the inner wall of the inner shell, thus reducing output and production efficiency, and the inconvenience of disassembling and assembling the connecting shaft and stirring blades, which also affects production efficiency.

[0006] To achieve the above objectives, the present invention provides the following technical solution: a chenodeoxycholic acid concentration and crystallization tank, comprising an outer shell, a top cover slidably connected to the upper surface of the outer shell, a filter assembly provided on the upper surface of the top cover, a temporary storage cover fixedly connected to the lower surface of the outer shell, an inner shell fixedly connected inside the temporary storage cover, a heating wire fixedly connected to the outer wall of the inner shell, a support frame fixedly connected to the upper surface of the top cover, and a stirring assembly provided on the inner wall of the support frame.

[0007] The stirring assembly includes a motor, the outer wall of which is fixedly connected to the inner wall of the bracket, the output end of which is fixedly connected to a rotating shaft, the outer wall of which is fixedly connected to a connecting shaft, the outer wall of which is fixedly connected to a square stirring blade, a pull rod slidably connected inside the connecting shaft, the pull rod slidably connected inside the rotating shaft, and a return spring provided on the outer wall of the pull rod, one end of which is fixedly connected to the outer wall of the connecting shaft.

[0008] Furthermore, the filter assembly includes an exhaust pipe, one end of which is fixedly connected to the upper surface of the top cover, and the other end of which is fixedly connected to a condenser pipe. One end of the condenser pipe is fixedly connected to an exhaust pipe, and one end of the exhaust pipe is fixedly connected to a waste bin.

[0009] Furthermore, a fixing screw is provided inside the top cover, and the outer wall of the fixing screw is threadedly connected to the inside of the outer shell.

[0010] Furthermore, the outer wall of the square stirring blade is slidably connected to the inner wall of the inner shell.

[0011] Furthermore, a control panel is fixedly connected to the outer wall of the housing.

[0012] Furthermore, an electric discharge valve is fixedly connected to the lower surface of the temporary storage cover.

[0013] Furthermore, the top cover is fixedly connected to a feed inlet.

[0014] Furthermore, a bracket is fixedly connected to the outer wall of the temporary storage cover.

[0015] This utility model has the following beneficial effects:

[0016] 1. In this utility model, the shape design of the square stirring blade can scrape off the crystals attached to the inner wall of the inner shell, preventing the crystals from being attached to the inner wall of the inner shell and reducing the final amount of chenodeoxycholic acid crystals, thus improving the production efficiency of chenodeoxycholic acid crystals. The cooperation between the pull rod and the return spring reduces the time for workers to disassemble and assemble the connecting shaft and the square stirring blade, further improving the production efficiency of chenodeoxycholic acid crystals.

[0017] 2. In this invention, the acidic gas generated during the evaporation of the solvent in the chenodeoxycholic acid solution enters the condenser through exhaust pipe one. The condenser quickly cools the acidic gas, liquefying it into small water droplets. These water droplets then flow into the waste bin through exhaust pipe two, thereby reducing the air pollution caused by the acidic gas generated during the production process and protecting the environment. Attached Figure Description

[0018] Figure 1This is a three-dimensional structural diagram of a chenodeoxycholic acid concentration and crystallization tank proposed in this utility model;

[0019] Figure 2 This invention relates to the structural concept of the heating wire portion of a chenodeoxycholic acid concentration and crystallization tank.

[0020] Figure 3 This is a schematic diagram of the square stirring blade part of a chenodeoxycholic acid concentration and crystallization tank proposed in this utility model.

[0021] Figure 4 This is a schematic diagram of the inlet section of a chenodeoxycholic acid concentration and crystallization tank proposed in this utility model.

[0022] Figure 5 This is a schematic diagram of the tie rod structure of a chenodeoxycholic acid concentration and crystallization tank proposed in this utility model.

[0023] Legend:

[0024] 1. Outer shell; 2. Control panel; 3. Top cover; 4. Fixing screws; 5. Feed inlet; 6. Motor; 7. Bracket 1; 8. Bracket 2; 9. Exhaust pipe 1; 10. Condenser pipe; 11. Exhaust pipe 2; 12. Waste bin; 13. Electric discharge valve; 14. Inner shell; 15. Heating wire; 16. Temporary storage cover; 17. Rotating shaft; 18. Connecting shaft; 19. Square stirring blade; 20. Pull rod; 21. Return spring. Detailed Implementation

[0025] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0026] Reference Figures 1-5This utility model provides an embodiment of a chenodeoxycholic acid concentration and crystallization tank, including an outer shell 1, a top cover 3 slidably connected to the upper surface of the outer shell 1, a filter assembly provided on the upper surface of the top cover 3, and a temporary storage cover 16 fixedly connected to the lower surface of the outer shell 1. Through the connection between the temporary storage cover 16 and the lower surface of the outer shell 1, the chenodeoxycholic acid crystals can be temporarily stored in the temporary storage cover 16 after precipitation. An inner shell 14 is fixedly connected inside the temporary storage cover 16, and a heating wire 15 is fixedly connected to the outer wall of the inner shell 14. Through the connection between the heating wire 15 and the inner shell 14, the heating wire 15 can heat the chenodeoxycholic acid solution inside the device through the inner shell 14 to evaporate the solvent. The separation of the heating wire 15 and the solution inside the device by the inner shell 14 avoids the heating wire 15 from direct contact with the solution and prevents the heating wire 15 from being damaged due to contact with water. A bracket 7 is fixedly connected to the upper surface of the top cover 3. Through the support of the bracket 7 for some components of the device, the device is more stable during operation. A stirring assembly is provided on the inner wall of the bracket 7.

[0027] The stirring assembly includes a motor 6, the outer wall of which is fixedly connected to the inner wall of a bracket 7. A rotating shaft 17 is fixedly connected to the output end of the motor 6, and a connecting shaft 18 is fixedly connected to the outer wall of the rotating shaft 17. A square stirring blade 19 is fixedly connected to the outer wall of the connecting shaft 18. The motor 6 drives the rotating shaft 17, causing it to rotate the connecting shaft 18 and the square stirring blade 19 fixedly connected to its outer wall, thereby stirring the chenodeoxycholic acid solution. This ensures uniform heating of the solution and improves the evaporation efficiency of the solvent. The shape design of the square stirring blade 19 helps to stir the solvent adhering to the inner shell. The crystals on the inner wall of the inner shell 14 are scraped off to prevent the crystals from adhering to the inner wall of the inner shell 14 and reducing the final amount of chenodeoxycholic acid crystals, thus improving the production efficiency of chenodeoxycholic acid crystals. A pull rod 20 is slidably connected inside the connecting shaft 18 and is slidably connected inside the rotating shaft 17. A return spring 21 is provided on the outer wall of the pull rod 20, and one end of the return spring 21 is fixedly connected to the outer wall of the connecting shaft 18. Through the cooperation of the pull rod 20 and the return spring 21, the time for workers to disassemble and assemble the connecting shaft 18 and the square stirring blade 19 is reduced, further improving the production efficiency of chenodeoxycholic acid crystals.

[0028] Reference Figure 1The filter assembly includes an exhaust pipe 9, one end of which is fixedly connected to the upper surface of the top cover 3, and the other end of which is fixedly connected to a condenser pipe 10. One end of the condenser pipe 10 is fixedly connected to an exhaust pipe 11, and one end of the exhaust pipe 11 is fixedly connected to a waste bin 12. The acidic gas generated when the solvent in the chenodeoxycholic acid solution evaporates will enter the condenser pipe 10 through the exhaust pipe 9. The condenser pipe 10 quickly cools the acidic gas, liquefying it into small water droplets. These small water droplets then flow into the waste bin 12 through the exhaust pipe 11, thereby reducing the pollution of the air by the acidic gas generated during the production process and protecting the environment.

[0029] Reference Figures 1-4 The top cover 3 has a fixing screw 4 inside, and the outer wall of the fixing screw 4 is threaded to the inside of the outer shell 1. The fixing screw 4 connects the top cover 3 to the outer shell 1 and the top cover 3, allowing the top cover 3 and the outer shell 1 to be detached, which facilitates the maintenance of the device by the staff. The outer wall of the square stirring blade 19 is slidably connected to the inner wall of the inner shell 14. Through the contact between the square stirring blade 19 and the inner shell 14, the square stirring blade 19 can scrape off the chenodeoxycholic acid crystals adhering to the inner wall of the inner shell 14, improving the production efficiency of the device for chenodeoxycholic acid crystals. The outer wall of the outer shell 1 is fixedly connected to a control plate 2, which controls the operation of the device. The control of plate 2 simplifies the operation of the device by the staff; the lower surface of the temporary storage cover 16 is fixedly connected to an electric discharge valve 13. The connection between the electric discharge valve 13 and the temporary storage cover 16 prevents the solution from leaking during operation and facilitates collection by the staff after the chenodeoxycholic acid crystals have completely precipitated, thereby improving the production efficiency of chenodeoxycholic acid crystals; the inside of the top cover 3 is fixedly connected to an inlet 5; the outer wall of the temporary storage cover 16 is fixedly connected to a support 2 8. The connection between the support 2 8 and the outer wall of the temporary storage cover 16 allows the support 2 8 to support the entire device, thereby improving the stability of the device during operation.

[0030] Working Principle: When the chenodeoxycholic acid concentration and crystallization tank is needed, the solution containing chenodeoxycholic acid is first poured into the crystallization tank through the inlet 5. Then, the heating wire 15 between the outer shell 1 and the inner shell 14 is heated by the control board 2. At the same time, the motor 6 is started, which drives the rotating shaft 17 to rotate, thereby driving the connecting shaft 18 and the square stirring blade 19 to stir the chenodeoxycholic acid solution in the tank. This allows the chenodeoxycholic acid solution to be heated and evaporated evenly. As the solvent continues to evaporate, the concentration of chenodeoxycholic acid in the solution gradually increases until it reaches saturation. At this time, chenodeoxycholic acid gradually crystallizes in the tank. Due to the shape design of the square stirring blade 19, the crystals adhering to the inner wall of the inner shell 14 are scraped down into the temporary storage cover 16, thereby preventing the precipitated crystals from adhering to the inner wall of the inner shell 14 and reducing the final crystal content, thus improving the quality of the produced chenodeoxycholic acid crystals. Because a small amount of crystals will adhere to the square stirring blade 19 and the connecting shaft 18, the connecting shaft 18 and the square stirring blade 19 need to be maintained or replaced regularly. At this point, the top cover 3 and the outer shell 1 are separated by rotating the fixing screw 4, thereby removing the connecting shaft 18 and the pull rod 20. The operator can pull the pull rod 20 by resisting the elastic force of the return spring 21, so that the pull rod 20 is disengaged from the inside of the rotating shaft 17 and the connecting shaft 18 and the square stirring blade 19 can be removed. This allows for maintenance of the connecting shaft 18 and the square stirring blade 19, reducing the operator's maintenance time and improving the precipitation efficiency of chenodeoxycholic acid crystals. During the heating and evaporation of the solvent, a large amount of acidic gas is emitted. The acidic gas is discharged into the condenser 10 through the exhaust pipe 1 9. The condenser 10 cools the acidic gas, causing it to liquefy into small water droplets, which then slide down the exhaust pipe 2 11 into the waste bin 12, thereby achieving the recovery of acidic gas and reducing the environmental impact of the production process. When the crystals have completely precipitated, the electric discharge valve 13 is opened by controlling the control board 2, so that the chenodeoxycholic acid crystals are discharged from the electric discharge valve 13, allowing the operator to complete the collection of chenodeoxycholic acid crystals.

[0031] Finally, it should be noted that the above description is only a preferred embodiment of the present utility model and is not intended to limit the present utility model. Although the present utility model has been described in detail with reference to the foregoing embodiments, those skilled in the art can still modify the technical solutions described in the foregoing embodiments or make equivalent substitutions for some of the technical features. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present utility model should be included within the protection scope of the present utility model.

Claims

1. A chenodeoxycholic acid concentration and crystallization tank, comprising an outer shell (1), characterized in that: A top cover (3) is slidably connected to the upper surface of the outer shell (1). A filter assembly is provided on the upper surface of the top cover (3). A temporary storage cover (16) is fixedly connected to the lower surface of the outer shell (1). An inner shell (14) is fixedly connected inside the temporary storage cover (16). A heating wire (15) is fixedly connected to the outer wall of the inner shell (14). A support (7) is fixedly connected to the upper surface of the top cover (3). A stirring assembly is provided on the inner wall of the support (7). The stirring assembly includes a motor (6), the outer wall of which is fixedly connected to the inner wall of the bracket (7), the output end of which is fixedly connected to a rotating shaft (17), the outer wall of which is fixedly connected to a connecting shaft (18), the outer wall of which is fixedly connected to a square stirring blade (19), the inner wall of which is fixedly connected to a pull rod (20), the inner wall of which is slidably connected to the rotating shaft (17), the outer wall of which is provided with a return spring (21), one end of which is fixedly connected to the outer wall of the connecting shaft (18).

2. The chenodeoxycholic acid concentration and crystallization tank according to claim 1, characterized in that: The filter assembly includes an exhaust pipe (9), one end of which is fixedly connected to the upper surface of the top cover (3), the other end of which is fixedly connected to a condenser pipe (10), one end of which is fixedly connected to an exhaust pipe (11), and one end of which is fixedly connected to a waste bin (12).

3. The chenodeoxycholic acid concentration and crystallization tank according to claim 1, characterized in that: The top cover (3) is provided with a fixing screw (4) inside, and the outer wall of the fixing screw (4) is threaded to the inside of the outer shell (1).

4. The chenodeoxycholic acid concentration and crystallization tank according to claim 1, characterized in that: The outer wall of the square stirring blade (19) is slidably connected to the inner wall of the inner shell (14).

5. The chenodeoxycholic acid concentration and crystallization tank according to claim 1, characterized in that: A control panel (2) is fixedly connected to the outer wall of the outer casing (1).

6. The chenodeoxycholic acid concentration and crystallization tank according to claim 1, characterized in that: An electric discharge valve (13) is fixedly connected to the lower surface of the temporary storage cover (16).

7. The chenodeoxycholic acid concentration and crystallization tank according to claim 1, characterized in that: The top cover (3) has an inlet (5) fixedly connected inside.

8. The chenodeoxycholic acid concentration and crystallization tank according to claim 1, characterized in that: The outer wall of the temporary storage cover (16) is fixedly connected to a bracket (8).

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