Negative pressure maintaining device of cell operation isolator

Abstract

The utility model relates to the technical field of negative pressure devices, in particular to a negative pressure maintaining device of a cell operation isolator, which comprises an isolator shell, an inner connecting pipe and a pressure sensor are arranged on the inner side of the isolator shell, a rectangular box body is arranged at the left end of the inner connecting pipe, and a plurality of air inlet holes are formed in the left side of the rectangular box body. An activated carbon filter block is arranged in the rectangular box body, a first exhaust pipe communicated with the inner connecting pipe is arranged on the outer side of the isolator shell, an antifouling assembly is arranged at the right end of the first exhaust pipe and comprises a filter box, an HEPA filter plate and an activated carbon filter plate are arranged in the filter box, and a second exhaust pipe is arranged on the right side of the filter box; a vacuum pump is arranged at the right end of the second exhaust pipe. The negative pressure maintaining device, the activated carbon filter block, the HEPA filter plate combination and the activated carbon filter plate filtration combination of the cell operation isolator can effectively remove particulate matters and harmful gases in air, ensure that the air discharged by the isolator is clean, and reduce the threat to the health of operators.

Description

TECHNICAL FIELD

[0001] The utility model relates to negative pressure device technical field, concretely is the negative pressure maintaining device of cell operation isolator. BACKGROUND

[0002] Cell operation isolator is a kind of equipment specially designed to provide sterile environment to carry out cell culture and operation. Its main function is to isolate cell samples from external environment, to prevent external pollutants (such as bacteria, fungi and viruses) from affecting cells, to ensure the accuracy of cell operation and the reliability of experimental results. Cell operation isolator is widely used in biomedical research, pharmaceutical industry and clinical laboratory, especially when dealing with high-risk biological materials (such as viruses, tumor cells and genetically engineered cells), its importance is particularly prominent.

[0003] In order to further improve the safety and effectiveness of cell operation isolator, negative pressure state is usually maintained. Negative pressure refers to the air pressure inside the isolator is lower than the external atmospheric pressure, this design can effectively prevent the pollutants in external air from entering the isolator. Negative pressure environment guides air flow from inside the isolator to the outside, forms an obstacle in the direction of air flow, reduces the risk of invasion of bacteria and other microorganisms in the air. In addition, negative pressure state helps to reduce the escape of harmful substances during cell culture and operation, thereby protecting the safety and health of operators.

[0004] However, in the process of realizing negative pressure, the work of extracting air in the isolator may cause a series of safety hazards. Because the air inside the isolator is extracted under negative pressure condition, these air may contain bacteria, viruses and other harmful biological substances. If the extracted air is not effectively treated, these potential pollutants may be released into the external environment during the operation of negative pressure maintaining device, causing environmental pollution or threatening the health of operators, in view of this, we propose the negative pressure maintaining device of cell operation isolator. UTILITY MODEL CONTENT

[0005] The utility model aims at providing the negative pressure maintaining device of cell operation isolator to solve the problems proposed in the above background technology.

[0006] In order to achieve the above-mentioned purpose, the utility model provides the following technical scheme:

[0007] The negative pressure maintaining device of the cell operation isolator comprises an isolator shell, an inner connecting pipe and a pressure sensor are arranged on the inner side of the isolator shell, the inner connecting pipe is responsible for guiding the air in the isolator to the anti-pollution assembly, and the pressure sensor monitors the air pressure in the isolator in real time to ensure the stability of the negative pressure environment, a rectangular box body is arranged at the left end of the inner connecting pipe and located in the cell operation isolator, a plurality of air inlet holes are formed in the left side of the rectangular box body, so that the air in the cell operation isolator can enter the rectangular box body, and an activated carbon filter block is arranged in the rectangular box body and used for preliminarily filtering the air extracted from the cell operation isolator.

[0008] A first air extraction pipe is arranged on the outer side of the isolator shell and communicates with the inner connecting pipe, an anti-pollution assembly is arranged at the right end of the first air extraction pipe, the first air extraction pipe guides the air in the inner connecting pipe into the filter box, the anti-pollution assembly comprises a filter box, a HEPA filter plate and an activated carbon filter plate are sequentially arranged in the filter box from left to right, the HEPA filter plate effectively captures particulate matters in the air, including bacteria and viruses, to ensure the cleanliness of the air, and the activated carbon filter plate adsorbs harmful gases in the air to further improve the filtering effect, a second air extraction pipe is arranged at the right side of the filter box and used for guiding the filtered air into a vacuum pump to complete the extraction of the air, the right end of the second air extraction pipe is provided with the vacuum pump, the pressure sensor and the vacuum pump are connected with a power supply and a controller, when the pressure sensor detects that the air pressure in the cell operation isolator is not up to standard, the vacuum pump extracts the air in the cell operation isolator to form a negative pressure environment and ensure the safety of cell operation.

[0009] Preferably, U-shaped positioning blocks are arranged on the upper and lower sides of the inner wall of the rectangular box body, and the activated carbon filter block is located between the two U-shaped positioning blocks and used for positioning the activated carbon filter block.

[0010] Preferably, a U-shaped operation port is formed in the front side of the rectangular box body, the front side of the activated carbon filter block passes through the U-shaped operation port to the outside, when the activated carbon filter block needs to be replaced, the activated carbon filter block can be pulled outwards to facilitate the disassembly and assembly of the activated carbon filter block.

[0011] Preferably, the first air extraction pipe and the second air extraction pipe both communicate with the filter box, a first electromagnetic valve is arranged on the first air extraction pipe, a second electromagnetic valve is arranged on the second air extraction pipe, the first electromagnetic valve and the second electromagnetic valve are connected with the controller through wires, when the vacuum pump works, the first electromagnetic valve and the second electromagnetic valve are opened, and when the vacuum pump is turned off, the first electromagnetic valve and the second electromagnetic valve are synchronously closed.

[0012] Preferably, the top of the filter box is of an open structure, a first U-shaped groove frame is arranged on the inner wall of the filter box and close to the left side, and the HEPA filter plate is inserted into the first U-shaped groove frame to facilitate the disassembly and assembly of the HEPA filter plate.

[0013] Preferably, the inner wall of the filter box is provided with a second U-shaped groove frame near the right side, and the activated carbon filter plate is inserted into the second U-shaped groove frame, facilitating the disassembly and assembly of the activated carbon filter plate.

[0014] Preferably, the top of the filter box is provided with a box cover, the front and rear sides of the box cover are provided with mounting holes a, the mounting holes a are connected with locking bolts, and threaded ends of the locking bolts are threadedly connected to the outer side of the filter box, facilitating the disassembly and assembly of the box cover, thereby facilitating the replacement of the HEPA filter plate or the activated carbon filter plate by the staff.

[0015] Preferably, the top of the inner wall of the box cover is attached with a rubber plate, and the bottom of the rubber plate is tightly attached to the top of the filter box, ensuring the sealing property of the connection between the box cover and the filter box.

[0016] Preferably, the outer side of the isolator shell is provided with an L-shaped support plate, and the filter box and the vacuum pump are fixedly connected to the top of the L-shaped support plate, supporting the filter box and the vacuum pump.

[0017] Preferably, the two sides of the inner wall of the L-shaped support plate are provided with a reinforcing rod, a plurality of mounting holes b are formed in the left side of the inner wall of the L-shaped support plate, and the mounting holes b are connected with screws, and threaded ends of the screws are threadedly connected to the outer side of the isolator shell, facilitating the disassembly and assembly of the L-shaped support plate.

[0018] Compared with the prior art, the cell operation isolator has the following beneficial effects:

[0019] 1. The negative pressure maintaining device of the cell operation isolator, the pressure sensor in the design can monitor the air pressure in the isolator in real time, detect and feedback the air pressure state in time, ensure the stability of the negative pressure environment, and when the air pressure is not up to standard, the vacuum pump will automatically start to continuously maintain the negative pressure, thereby further enhancing the safety and reliability of the operation.

[0020] 2. The negative pressure maintaining device of the cell operation isolator, the activated carbon filter block, the HEPA filter plate combination and the activated carbon filter plate combination can effectively remove particulate matter and harmful gases in the air, ensure that the air discharged by the isolator is clean, and reduce the health threat to the operator.

[0021] 3. The negative pressure maintaining device of the cell operation isolator has a design facilitating maintenance and replacement, such as the structure design of the U-shaped operation port, the U-shaped groove frame and the box cover, so that the staff can conveniently and quickly operate when replacing the activated carbon filter block, the HEPA filter plate combination and the activated carbon filter plate, thereby improving the usability and maintenance efficiency of the equipment. BRIEF DESCRIPTION OF DRAWINGS

[0022] Figure 1The whole first visual angle structure schematic diagram of the utility model shows that the filter box is arranged in the rectangular box body, and the HEPA filter plate and the active carbon filter plate are arranged in the filter box.

[0023] Figure 2 The whole second visual angle structure schematic diagram of the utility model shows that the filter box is arranged in the rectangular box body, and the HEPA filter plate and the active carbon filter plate are arranged in the filter box.

[0024] Figure 3 The assembly structure schematic diagram of the inner connecting pipe, the rectangular box body and the active carbon filter block in the utility model shows that the inner connecting pipe is arranged in the rectangular box body, and the active carbon filter block is arranged in the inner connecting pipe.

[0025] Figure 4 The cross section structure schematic diagram of the rectangular box body in the utility model shows that the HEPA filter plate and the active carbon filter plate are arranged in the filter box.

[0026] Figure 5 The partial structure schematic diagram of the utility model shows that the filter box is arranged in the rectangular box body, and the HEPA filter plate and the active carbon filter plate are arranged in the filter box.

[0027] Figure 6 The cross section structure schematic diagram of the filter box in the utility model shows that the HEPA filter plate and the active carbon filter plate are arranged in the filter box.

[0028] In the figure: 1, isolator shell; 2, inner connecting pipe; 3, rectangular box body; 30, air inlet hole; 31, U-shaped positioning block; 32, U-shaped operation port; 4, active carbon filter block; 5, first air suction pipe; 50, first electromagnetic valve; 6, anti-fouling assembly; 60, filter box; 600, first U-shaped groove frame; 601, second U-shaped groove frame; 61, HEPA filter plate; 62, active carbon filter plate; 63, box cover; 630, mounting hole a; 64, rubber plate; 65, locking bolt; 7, second air suction pipe; 70, second electromagnetic valve; 8, vacuum pump; 9, L-shaped support plate; 90, reinforcing rod; 91, mounting hole b; 10, pressure sensor; 11, screw. DETAILED DESCRIPTION

[0029] The technical solutions in the embodiments of the utility model will be clearly and completely described below with reference to the drawings in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, rather than all the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by those skilled in the art without creative labor belong to the scope of protection of the utility model.

[0030] In the description of the utility model, it should be understood that the orientation or positional relationship indicated by the terms "center", "longitudinal", "transverse", "length", "width", "thickness", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise" are based on the orientation or positional relationship shown in the drawings, and are only for the convenience of describing the utility model and simplifying the description, and therefore cannot be understood as indicating or implying that the devices or elements referred to must have a particular orientation, be constructed and operated in a particular orientation, and therefore cannot be understood as limiting the utility model.

[0031] Referring to Figures 1-6 The utility model provides a technical scheme:

[0032] The negative pressure maintaining device of the cell operation isolator comprises an isolator shell 1, an inner connecting pipe 2 and a pressure sensor 10 are arranged on the inner side of the isolator shell 1, the inner connecting pipe 2 is responsible for guiding the air in the isolator to an anti-pollution assembly 6, the pressure sensor 10 monitors the air pressure inside the isolator in real time to ensure the stability of the negative pressure environment, a rectangular box body 3 is arranged at the left end of the inner connecting pipe 2 and located inside the cell operation isolator, a plurality of air inlet holes 30 are formed in the left side of the rectangular box body 3, so that the air in the cell operation isolator can enter the rectangular box body 3, and an activated carbon filter block 4 is arranged in the rectangular box body 3 and used for preliminarily filtering the air drawn out of the cell operation isolator.

[0033] A first air extraction pipe 5 in communication with the inner connecting pipe 2 is arranged on the outer side of the isolator shell 1, an anti-pollution assembly 6 is arranged at the right end of the first air extraction pipe 5, the first air extraction pipe 5 guides the air in the inner connecting pipe 2 into a filter box 60, the anti-pollution assembly 6 comprises the filter box 60, a HEPA filter plate 61 and an activated carbon filter plate 62 are sequentially arranged in the filter box 60 from left to right, the HEPA filter plate 61 effectively captures particulate matters in the air, including bacteria and viruses, to ensure the air clean, the activated carbon filter plate 62 adsorbs harmful gases in the air to further improve the filtering effect, a second air extraction pipe 7 is arranged at the right side of the filter box 60 and used for guiding the filtered air into a vacuum pump 8 to complete the extraction of the air, the right end of the second air extraction pipe 7 is provided with the vacuum pump 8, the pressure sensor 10 and the vacuum pump 8 are connected with a power supply and a controller to work, when the pressure sensor 10 detects that the air pressure in the cell operation isolator does not meet the standard, the vacuum pump 8 extracts the air in the cell operation isolator to form a negative pressure environment and ensure the safety of cell operation.

[0034] In the embodiment, U-shaped positioning blocks 31 are arranged on the upper and lower sides of the inner wall of the rectangular box body 3, and the activated carbon filter block 4 is located between the two U-shaped positioning blocks 31 and used for positioning the activated carbon filter block 4.

[0035] Specifically, a U-shaped operation port 32 is formed in the front side of the rectangular box body 3, and the front side of the activated carbon filter block 4 passes through the U-shaped operation port 32 to the outside, when the activated carbon filter block 4 needs to be replaced, the activated carbon filter block 4 can be extracted outward by the staff, so that the activated carbon filter block 4 can be disassembled and assembled.

[0036] Further, the first suction pipe 5 and the second suction pipe 7 are both in communication with the filter box 60, the first suction pipe 5 is provided with a first electromagnetic valve 50, the second suction pipe 7 is provided with a second electromagnetic valve 70, the first electromagnetic valve 50 and the second electromagnetic valve 70 are respectively in communication with the controller through wires, when the vacuum pump 8 works, the first electromagnetic valve 50 and the second electromagnetic valve 70 are opened, when the vacuum pump 8 is closed, the first electromagnetic valve 50 and the second electromagnetic valve 70 are synchronously closed.

[0037] Further, the top of the filter box 60 is an open structure, the inner wall of the filter box 60 and the position close to the left side are provided with a first U-shaped groove frame 600, the HEPA filter plate 61 is inserted into the first U-shaped groove frame 600, which facilitates the disassembly and assembly of the HEPA filter plate 61.

[0038] Further, the inner wall of the filter box 60 and the position close to the right side are provided with a second U-shaped groove frame 601, the activated carbon filter plate 62 is inserted into the second U-shaped groove frame 601, which facilitates the disassembly and assembly of the activated carbon filter plate 62.

[0039] Further, the top of the filter box 60 is provided with a box cover 63, the front and rear sides of the box cover 63 are both provided with mounting holes a630, the mounting holes a630 are connected with locking bolts 65, the threaded ends of the locking bolts 65 are threadedly connected to the outer side of the filter box 60, which facilitates the disassembly and assembly of the box cover 63, thereby facilitating the replacement of the HEPA filter plate 61 or the activated carbon filter plate 62 by the staff.

[0040] Further, the top of the inner wall of the box cover 63 is bonded with a rubber plate 64, the bottom of the rubber plate 64 is tightly attached to the top of the filter box 60, which ensures the sealing performance of the connection between the box cover 63 and the filter box 60.

[0041] Further, the outer side of the isolator shell 1 is provided with an L-shaped support plate 9, the filter box 60 and the vacuum pump 8 are both fixedly connected to the top of the L-shaped support plate 9, which supports the filter box 60 and the vacuum pump 8.

[0042] Further, the two sides of the inner wall of the L-shaped support plate 9 are provided with reinforcing rods 90, the left side of the inner wall of the L-shaped support plate 9 is provided with a plurality of mounting holes b91, the mounting holes b91 are connected with screws 11, the threaded ends of the screws 11 are threadedly connected to the outer side of the isolator shell 1, which facilitates the disassembly and assembly of the L-shaped support plate 9.

[0043] When the negative pressure maintaining device of the cell operation isolator of the embodiment is used, after the power is turned on, the system is started, the pressure sensor 10 will monitor the air pressure in the isolator in real time, to ensure the establishment of the negative pressure environment, the inner connecting pipe 2 begins to guide the air in the isolator to the anti-fouling assembly 6, the air enters the rectangular box body 3 through a plurality of air inlet holes 30, here, the activated carbon filter block 4 preliminarily filters the air to remove harmful gases and odors;

[0044] Subsequently, the pretreated air flows into the filter box 60 through the first suction pipe 5, and in the filter box 60, the air passes through the HEPA filter plate 61 and the activated carbon filter plate 62 in sequence, further removing bacteria, viruses and other particulate matters, and the cleaned air is sent into the vacuum pump 8 through the second suction pipe 7 for effective extraction, forming a negative pressure environment and ensuring the safety of cell operation.

[0045] During operation, if the pressure sensor 10 detects that the air pressure does not reach the set standard, the vacuum pump 8 will automatically start to continuously maintain the negative pressure state, protecting the health of the operator and the accuracy of the experiment, when the activated carbon filter block 4 needs to be replaced, the worker can simply pull out the old filter block outward through the U-shaped operation port 32, facilitating disassembly and assembly, when the HEPA filter plate 61 or the activated carbon filter plate 62 needs to be replaced, the worker detaches the two locking bolts 65, then opens the box cover 63, and then the HEPA filter plate 61 or the activated carbon filter plate 62 can be replaced, during the whole process, the worker ensures that the box cover 63 of the filter box 60 is fixed through the locking bolt 65, so as to prevent air leakage.

[0046] The basic principle, main features and advantages of the present application are shown and described above. It should be understood by those skilled in the art that the present application is not limited by the above embodiments, and the above embodiments and descriptions in the specification are only preferred examples of the present application and are not intended to limit the present application. Without departing from the spirit and scope of the present application, various changes and improvements can be made to the present application, and these changes and improvements all fall within the scope of the present application. The scope of protection of the present application is defined by the appended claims and their equivalents.

Claims

1. A negative pressure maintaining device for a cell manipulation isolator, comprising an isolator housing (1), characterized in that: The inner side of the isolator shell (1) is provided with an inner connecting pipe (2) and a pressure sensor (10), the left end of the inner connecting pipe (2) is provided with a rectangular box body (3), a plurality of air inlet holes (30) are formed in the left side of the rectangular box body (3), and an activated carbon filter block (4) is arranged in the rectangular box body (3), the outer side of the isolator shell (1) is provided with a first air exhaust pipe (5) in communication with the inner connecting pipe (2), the right end of the first air exhaust pipe (5) is provided with an anti-fouling assembly (6), the anti-fouling assembly (6) comprises a filter box (60), the filter box (60) is sequentially provided with a HEPA filter plate (61) and an activated carbon filter plate (62) from left to right, the right side of the filter box (60) is provided with a second air exhaust pipe (7), and the right end of the second air exhaust pipe (7) is provided with a vacuum pump (8).

2. The negative pressure maintenance device for a cell manipulation isolator according to claim 1, wherein: The upper and lower sides of the inner wall of the rectangular box body (3) are both provided with U-shaped positioning blocks (31), and the activated carbon filter block (4) is located between the two U-shaped positioning blocks (31).

3. The negative pressure maintenance device for a cell manipulation isolator of claim 1, wherein: A U-shaped operation port (32) is formed in the front side of the rectangular box body (3), and the front side of the activated carbon filter block (4) passes through the U-shaped operation port (32) to the outside.

4. The negative pressure maintenance device for a cell manipulation isolator of claim 1, wherein: The first air exhaust pipe (5) and the second air exhaust pipe (7) are both in communication with the filter box (60), the first air exhaust pipe (5) is provided with a first electromagnetic valve (50), and the second air exhaust pipe (7) is provided with a second electromagnetic valve (70).

5. The negative pressure maintenance device for a cell manipulation isolator of claim 1, wherein: The top of the filter box (60) is of an open structure, the inner wall of the filter box (60) and the position close to the left side are provided with a first U-shaped groove frame (600), and the HEPA filter plate (61) is inserted into the first U-shaped groove frame (600).

6. The negative pressure maintenance device for a cell manipulation isolator of claim 1, wherein: The inner wall of the filter box (60) and the position close to the right side are provided with a second U-shaped groove frame (601), and the activated carbon filter plate (62) is inserted into the second U-shaped groove frame (601).

7. The negative pressure maintenance device for a cell manipulation isolator of claim 1, wherein: A box cover (63) is sleeved on the top of the filter box (60), mounting holes a (630) are formed in the front and rear sides of the box cover (63), the mounting holes a (630) are connected with locking bolts (65), and the threaded ends of the locking bolts (65) are threadedly connected to the outer side of the filter box (60).

8. The negative pressure maintenance device for a cell manipulation isolator of claim 7, wherein: A rubber plate (64) is attached to the top of the inner wall of the box cover (63), and the bottom of the rubber plate (64) is tightly attached to the top of the filter box (60).

9. The negative pressure maintenance device for a cell manipulation isolator of claim 1, wherein: The outer side of the isolator shell (1) is provided with an L-shaped supporting plate (9), and the filter box (60) and the vacuum pump (8) are fixedly connected to the top of the L-shaped supporting plate (9).

10. The negative pressure maintenance device for a cell manipulation isolator of claim 9, wherein: A reinforcing rod (90) is arranged between the two sides of the inner wall of the L-shaped supporting plate (9), a plurality of mounting holes b (91) are formed in the left side of the inner wall of the L-shaped supporting plate (9), the mounting holes b (91) are connected with screws (11), and the threaded ends of the screws (11) are threadedly connected to the outer side of the isolator shell (1).

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