Capsule containing nano coenzyme Q10 particles

Abstract

The utility model discloses a capsule containing nano coenzyme Q10 particles, and relates to the technical field of capsules. The nano coenzyme Q10 capsule comprises an inner capsule shell, the inner capsule shell is filled with nano coenzyme Q10 particle bodies, the periphery of the inner capsule shell is fixedly connected with a supporting frame, the periphery of the supporting frame is fixedly connected with an outer capsule shell, and the supporting frame is arranged to be a six-grid supporting membrane. According to the application, the support frame is matched with the nano coenzyme Q10 particle body for use, so that multiple medicines can be uniformly separated and stored between the inner capsule shell and the outer capsule shell by using the support frame, and the nano coenzyme Q10 particle body is released to be mixed with the multiple medicines under the condition that the outer capsule shell and the inner capsule shell are corroded by gastric acid, so that the effect of improving the bioavailability is achieved. And the coenzyme Q10 is rapidly absorbed through intestinal tracts, so that the bioavailability and the treatment efficiency of the coenzyme Q10 are effectively improved, the contact reaction caused by long-time storage and contact of a plurality of medicines is reduced, and the treatment effect of the medicines is maintained.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of capsules, in particular to a capsule containing nano Coenzyme Q10 particles. BACKGROUND

[0002] Coenzyme Q10 (CoQ10) is a liposoluble quinone compound widely distributed in human cells, particularly in organs with high energy demand such as the heart, liver, and kidneys. It plays a key role in cellular energy metabolism, participating in electron transfer in the mitochondrial respiratory chain and ATP synthesis. In addition to energy metabolism, Coenzyme Q10 has strong antioxidant function, can scavenge free radicals, protect cell membranes from oxidative damage, and is essential for maintaining cardiovascular health. As age increases, the body's ability to synthesize Coenzyme Q10 gradually weakens, therefore, exogenous supplementation of Coenzyme Q10 has significant implications for maintaining a healthy state. Currently, Coenzyme Q10 is available in various forms, including soft capsules, oral liquids, powders, and tablets.

[0003] Due to the liposoluble nature of Coenzyme Q10, its solubility in water is low, which limits its bioavailability. To overcome this limitation, researchers have developed various technologies, particularly nanotechnology, to improve the absorption and bioavailability of Coenzyme Q10. For example, by mixing Coenzyme Q10 with ingredients such as caprylic / capric glyceride, phospholipids, etc., emulsification can be prepared into nano-microcapsule emulsion with an average particle size of less than 100 nanometers, thereby enhancing its dispersibility in water and biocompatibility. In addition, there are studies that mix Coenzyme Q10 with piperine, antioxidants, etc., and then perform high-pressure homogenization and spray drying to prepare water-soluble nano Coenzyme Q10 microcapsules. The application of these technologies has significantly improved the stability, water dispersibility, and bioavailability of Coenzyme Q10.

[0004] Although existing technologies have made some progress in improving the bioavailability of Coenzyme Q10, challenges still exist in practical applications. In particular, when multiple drugs are stored together to improve convenience of use, interactions between different drug molecules may occur, which can affect the effectiveness of the drugs and reduce the treatment efficiency of patients. UTILITY MODEL CONTENT

[0005] The purpose of the present application is to solve the problem that when multiple drugs are stored together to improve convenience of use, interactions between different drug molecules may occur, which can affect the effectiveness of the drugs and reduce the treatment efficiency of patients. The present application provides a capsule containing nano Coenzyme Q10 particles.

[0006] The present application specifically adopts the following technical solutions to achieve the above-mentioned purposes:

[0007] The capsule containing nano coenzyme Q10 particles comprises an inner capsule shell, the inside of which is filled with a nano coenzyme Q10 particle body, the periphery of the inner capsule shell is fixedly connected with a support frame, the periphery of the support frame is fixedly connected with an outer capsule shell, and the support frame is provided as a six-mesh support membrane.

[0008] By adopting the above technical scheme, the support frame is used in cooperation with the nano coenzyme Q10 particle body, so that the support frame is used to uniformly separate and store multiple drugs between the inner capsule shell and the outer capsule shell, and in the case that the outer capsule shell and the inner capsule shell are corroded by gastric acid, the nano coenzyme Q10 particle body and the multiple drugs are mixed and quickly absorbed through the intestinal tract, thereby effectively improving the bioavailability and treatment efficiency of coenzyme Q10, reducing the contact reaction caused by long-term storage of multiple drugs, and maintaining the treatment effect of the drugs.

[0009] Further, the inner side of the outer capsule shell is fixedly connected with a cellulose reinforced mesh film.

[0010] By adopting the above technical scheme, the cellulose reinforced mesh film is used in cooperation with the outer capsule shell, so that the surface tensile strength of the outer capsule shell is effectively improved, and the practicality of the capsule is improved.

[0011] Further, the outer side of the outer capsule shell is fixedly connected with a PVA lubricating coating.

[0012] By adopting the above technical scheme, the PVA lubricating coating is used in cooperation with the outer capsule shell, so that the lubricity of the surface of the outer capsule shell is effectively improved, and the comfort of a user when swallowing the capsule is improved.

[0013] Further, the middle sections of the inner capsule shell, the outer capsule shell and the PVA lubricating coating are fixedly connected with middle section division rings.

[0014] By adopting the above technical scheme, the middle section division rings effectively improve the vulnerability of the middle sections of the inner capsule shell, the outer capsule shell and the PVA lubricating coating, so that the capsule can be easily separated at the middle section, and the applicability of the capsule is improved.

[0015] Further, the surface of the PVA lubricating coating is uniformly coated with a plurality of fluorescent nano coatings.

[0016] By adopting the above technical scheme, the fluorescent nano coatings can emit light in a dark environment, so that the visibility of the capsule when falling in a dark environment is effectively improved, resource waste is reduced, and the practicality of the capsule is improved.

[0017] Further, one end of the outer capsule shell is fixedly connected with a gelatin thickening layer.

[0018] By adopting the above technical scheme, the wear resistance of one end of the outer capsule shell is effectively improved through the cooperation of the outer capsule shell and the gelatin thickening layer, the rupture of the outer capsule shell caused by picking up is reduced, and the practicability of the capsule is improved.

[0019] Further, the surface of the gelatin thickening layer is fixedly connected with a plurality of gelatin convex rings.

[0020] By adopting the above technical scheme, the roughness of the surface of the gelatin thickening layer is effectively improved through the setting of the gelatin convex rings, and the separation of the capsule from the hand during picking up the capsule is reduced.

[0021] To sum up, the present application has at least one of the following beneficial effects:

[0022] 1. By setting the support frame in cooperation with the nano coenzyme Q10 particle body, the support frame is used to uniformly separate and store a plurality of drugs between the inner capsule shell and the outer capsule shell, and in the case that the outer capsule shell and the inner capsule shell are corroded by gastric acid, the nano coenzyme Q10 particle body and the plurality of drugs are mixed and quickly absorbed through the intestinal tract, effectively improving the bioavailability and treatment efficiency of coenzyme Q10, reducing the contact reaction caused by long-term storage of a plurality of drugs, and maintaining the treatment effect of the drugs.

[0023] 2. By using the characteristic that the fluorescent nano coating can emit light in a dark environment, the visibility of the capsule when falling in a dark environment is effectively improved, the waste of resources is reduced, and the practicability of the capsule is improved. BRIEF DESCRIPTION OF DRAWINGS

[0024] Figure 1 is a perspective structural schematic diagram of the device body in the present application.

[0025] Figure 2 is an exploded view of the device body in the present application.

[0026] Figure 3 is a perspective structural schematic diagram of the support frame in the present application.

[0027] Figure 4 is a perspective structural schematic diagram of the gelatin thickening layer in the present application.

[0028] BRIEF DESCRIPTION OF DRAWINGS:

[0029] 1, inner capsule shell; 2, nano coenzyme Q10 particle body; 3, support frame; 4, outer capsule shell; 5, cellulose reinforced web film; 6, PVA lubricating coating; 7, middle segment division ring; 8, fluorescent nano coating; 9, gelatin thickening layer; 10, gelatin convex ring. DETAILED DESCRIPTION

[0030] The following will be described in detail in combination with the accompanying Figure 1The application is further described in detail.

[0031] The application discloses a capsule containing nano coenzyme Q10 particles.

[0032] Referring to Figure 1 - Figure 3 The capsule containing nano coenzyme Q10 particles comprises an inner capsule shell 1, the inside of the inner capsule shell 1 is filled with a nano coenzyme Q10 particle body 2, a support frame 3 is fixedly connected to the periphery of the inner capsule shell 1, an outer capsule shell 4 is fixedly connected to the periphery of the support frame 3, and the support frame 3 is provided as a hexagonal grid support diaphragm.

[0033] In use, the nano coenzyme Q10 particle body 2 is first obtained by a supercritical CO2 extraction technology, then mixed with an appropriate amount of lactose, microcrystalline cellulose and other auxiliary materials, and filled into a preformed inner capsule shell 1, then the inner capsule shell 1 is tightly sealed by mechanical pressure, then the space between the inner capsule shell 1 and the outer capsule shell 4 is divided into six evenly divided spaces by setting a hexagonal grid support diaphragm, and different drugs required by a user are filled in the six evenly divided spaces, and after the filling is completed, the outer capsule shell 4 is tightly sealed by mechanical pressure, so that after the user swallows the capsule, the outer capsule shell 4 is rapidly decomposed under the action of gastric acid, releasing the drugs separated by the support frame 3, then as the outer capsule shell 4 is decomposed, the gastric acid contacts the inner capsule shell 1 and rapidly decomposes the inner capsule shell 1, so that the nano coenzyme Q10 particle body 2 filled in the inner capsule shell 1 is released and mixed with the drugs required by the user, then the drugs are rapidly diffused and efficiently absorbed in the intestinal tract by using the extremely small size characteristics of the nano coenzyme Q10 particle body 2, effectively improving the bioavailability and treatment efficiency of coenzyme Q10, reducing the contact reaction generated by the long-term storage of multiple drugs, and maintaining the treatment effect of the drugs.

[0034] Referring to Figure 1 and Figure 2 The inner side of the outer capsule shell 4 is fixedly connected with a cellulose reinforced mesh film 5.

[0035] In use, the cellulose reinforced mesh film 5 is arranged to form a mesh reinforced structure on the inner side of the outer capsule shell 4, and the good mechanical strength and biocompatibility of the cellulose reinforced mesh film 5 effectively enhance the tensile strength of the surface of the outer capsule shell 4, improving the tensile effect of the capsule.

[0036] Referring to Figure 1 and Figure 2 The outer side of the outer capsule shell 4 is fixedly connected with a PVA lubricating coating 6.

[0037] In use, the surface of the outer capsule shell 4 is wrapped by setting the PVA lubricating coating 6 to separate the direct contact between the outer capsule shell 4 and the throat of the user, and to improve the comfort of the user when swallowing the capsule by using the good film-forming property and lubricity of the PVA lubricating coating 6.

[0038] Referring to Figure 1 - Figure 3 The middle segment of the inner capsule shell 1, the outer capsule shell 4 and the PVA lubricating coating 6 are fixedly connected with the middle segment division ring 7.

[0039] In use, when the medicine inside the capsule needs to be used externally, the middle segment division ring 7 is rotated and pulled by manually twisting the outer capsule shell 4 to drive the inner capsule shell 1, so that the middle segment division ring 7 is broken, and the medicine inside the inner capsule shell 1 and the outer capsule shell 4 flows out through the broken opening of the middle segment division ring 7, thereby effectively improving the applicability of the device.

[0040] Referring to Figure 1 and Figure 2 The surface of the PVA lubricating coating 6 is uniformly coated with a plurality of fluorescent nano coatings 8.

[0041] In use, the fluorescent nano coating 8 is set on the surface of the PVA lubricating coating 6, and the fluorescent nano coating 8 can emit light in a dark environment, so that the user can quickly observe the falling position of the capsule through the light-emitting fluorescent nano coating 8 when the capsule falls in a dark environment, and pick it up, reducing the waste of resources and improving the practicality of the capsule.

[0042] Referring to Figure 1 and Figure 4 One end of the outer capsule shell 4 is fixedly connected with a gelatin thickening layer 9.

[0043] In use, the wear resistance of one end of the outer capsule shell 4 is enhanced by setting the gelatin thickening layer 9, so that the user can indirectly clamp the outer capsule shell 4 through the gelatin thickening layer 9 when picking up the outer capsule shell 4 with the hand, thereby reducing the rupture of the outer capsule shell 4 caused by picking up, and further improving the practicality of the capsule.

[0044] Referring to Figure 1 and Figure 4 The surface of the gelatin thickening layer 9 is fixedly connected with a plurality of gelatin convex rings 10.

[0045] In use, the roughness of the surface of the gelatin thickening layer 9 is effectively improved by fixedly connecting a plurality of gelatin convex rings 10 on the surface of the gelatin thickening layer 9, the wear resistance between the gelatin thickening layer 9 and the hand is increased, the capsule is less likely to fall off the hand when picking up the capsule through the gelatin thickening layer 9, and the practicality of the capsule is improved.

[0046] The implementation principle of the capsule containing the nano coenzyme Q10 particle in this embodiment is as follows: first, the nano coenzyme Q10 particle body 2 is obtained by the supercritical CO2 extraction technology, then the nano coenzyme Q10 particle body 2 is mixed with appropriate amount of lactose, microcrystalline cellulose and other auxiliary materials, and filled into the preformed inner capsule shell 1, then the inner capsule shell 1 is tightly sealed by mechanical pressure, then the space between the inner capsule shell 1 and the outer capsule shell 4 is divided into six equal spaces by setting the six-mesh support diaphragm, and the different drugs required by the user are filled in the six equal spaces, and after the filling is completed, the outer capsule shell 4 is tightly sealed by mechanical pressure;

[0047] Then the surface of the outer capsule shell 4 is wrapped by setting the PVA lubricating coating 6, which separates the direct contact between the outer capsule shell 4 and the throat of the user, and improves the comfort of the user when swallowing the capsule by using the good film-forming property and lubricity of the PVA lubricating coating 6;

[0048] Then after the user swallows the capsule, first, the outer capsule shell 4 is rapidly decomposed under the action of gastric acid, releasing the drugs separated by the support frame 3, then as the outer capsule shell 4 is decomposed, the gastric acid contacts the inner capsule shell 1 and rapidly decomposes the inner capsule shell 1, so that the nano coenzyme Q10 particle body 2 filled in the inner capsule shell 1 is released and mixed with the drugs required by the user, then the drugs are rapidly diffused by using the extremely small size characteristics of the nano coenzyme Q10 particle body 2, and are efficiently absorbed in the intestinal tract;

[0049] And when the capsule falls in a dark environment, the user can quickly observe the falling position of the capsule by the luminescent fluorescent nano coating 8 and pick it up.

Claims

1. Capsule containing nano coenzyme Q10 particles, comprising an inner capsule shell (1), characterized in that: The inside of the inner capsule shell (1) is filled with nano coenzyme Q10 particle body (2), the periphery of the inner capsule shell (1) is fixedly connected with a support frame (3), the periphery of the support frame (3) is fixedly connected with an outer capsule shell (4), and the support frame (3) is provided as a six-mesh support diaphragm.

2. The capsule containing nano coenzyme Q10 particles according to claim 1, characterized by: The inner side of the outer capsule shell (4) is fixedly connected with a cellulose reinforced net film (5).

3. The capsule containing nano coenzyme Q10 particles according to claim 1, characterized by: The outer side of the outer capsule shell (4) is fixedly connected with a PVA lubricating coating (6).

4. The capsule containing nano coenzyme Q10 particles according to claim 3, characterized by: The middle section of the inner capsule shell (1), the outer capsule shell (4) and the PVA lubricating coating (6) are all fixedly connected with a middle section segmentation ring (7).

5. The capsule containing nano coenzyme Q10 particles according to claim 4, characterized by: The surface of the PVA lubricating coating (6) is uniformly coated with a plurality of fluorescent nano coatings (8).

6. The capsule containing nano coenzyme Q10 particles according to claim 1, characterized by: One end of the outer capsule shell (4) is fixedly connected with a gelatin thickening layer (9) in a symmetrical manner.

7. The capsule containing nano-sized coenzyme Q10 particles according to claim 6, characterized by: The surface of the gelatin thickening layer (9) is fixedly connected with a plurality of gelatin convex rings (10).

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