Cassette bottle medicine high-voltage discharge test support

Abstract

The utility model belongs to the field of high-voltage discharge testing, and particularly discloses a high-voltage discharge testing support for cartridge type medicine bottles, a motor transmits torque through a miniature corrugated pipe coupling, a driving gear rotates to drive two driven gears to rotate so as to further drive a supporting roller to rotate, and the supporting roller rotates to drive the cartridge type medicine bottles to rotate stably. A dovetail guide rail sliding block is adopted for installation, a miniature corrugated pipe coupler is adopted for connection with a motor, installation, replacement and replacement are convenient, the professional requirement for detection personnel is low, the detection accuracy is high, the detection efficiency is high, the detection cost is low, and the detection efficiency is high. According to the utility model, the parts to be processed and the part close to the electrode are all made of insulating materials, so that the abnormal detection result caused by the material property is avoided, and the device can be adapted to various medicines with different specifications, and has strong inclusiveness.

Description

Technical Field

[0001] This utility model relates to the field of high-voltage discharge testing technology, specifically a high-voltage discharge testing bracket for cartridge-type medicines. Background Technology

[0002] Similar to traditional high-voltage discharge, the principle of micro-current high-voltage discharge method is to apply a high voltage to the sample to be tested and determine whether the packaging is leaking based on the difference in electrical parameters between defective and undefective packaging. Micro-current high-voltage discharge method requires that the packaging itself is non-conductive, while the contents (generally requiring a filling volume greater than 30%) must be conductive. Therefore, it is not suitable for testing powder injections and lyophilized injections.

[0003] High-voltage discharge and vacuum decay methods are both cited in the United States Pharmacopeia. Microcurrent high-voltage discharge, as a complementary method to vacuum decay, can jointly solve the leakage detection of various injectables, including powder injections, lyophilized products, conventional and unconventional liquid injections, in order to meet the challenges brought by strict regulations.

[0004] In recent years, China's regulations on consistency evaluation of injectable drugs have clearly required verification of packaging sealing. Due to the large variety of injectable drugs, some injectable drugs, especially biological products, have unconventional water injection properties such as suspensions, emulsions, proteins, or viscous liquids. The currently popular vacuum attenuation method can no longer solve the application of such drugs, and the microcurrent high voltage discharge method will be the ideal choice.

[0005] High-voltage discharge micro-current leak detector

[0006] The E-Scan 655 is a definitive offline microleak tester that uses a novel type of high-voltage discharge technology to test the closure integrity of vials, pre-syringes, and other liquid-filled injectable products. The E-Scan 655 technology is a microcurrent conductivity testing method, HVLDmc, which is a completely non-destructive method for both the container and the product; it exposes the packaging and product to a voltage lower than that of other conductive solutions. This technology employs a non-contact and non-invasive testing method, requiring no sample preparation. The E-Scan 655 can be used for a variety of liquid products, including low-conductivity sterile water for injection (WFI) and protein products containing suspensions.

[0007] The E-Scan655 offline microleak tester requires the drug to be placed on a support for testing. Existing supports suffer from unstable drug rotation speeds and axial movement during testing, and are inconvenient to connect and install with the equipment. Therefore, a high-voltage discharge test support for cartridge-type drugs is proposed. Utility Model Content

[0008] The purpose of this invention is to provide a high-voltage discharge test bracket for cartridge-type medicines to solve the problems mentioned in the background art.

[0009] To achieve the above objectives, this utility model provides the following technical solution: a high-voltage discharge test bracket for cartridge-type medicines, comprising a drive shaft, a gearbox inserted into the drive shaft, and a gear cover plate and a V-groove plate connected via a base;

[0010] The gearbox has a gear groove on one side, and two support roller holes and a main shaft through hole are provided in the gear groove. One end of the drive shaft is connected to a miniature bellows coupling. The miniature bellows coupling passes through the through hole at the top of the gearbox and is connected to the drive gear. The drive gear is located at the main shaft through hole. The bottom sides of the drive gear are respectively engaged with the corresponding driven gears, and the driven gears are located at the corresponding support roller holes. The driven gears are respectively connected to the support rollers that pass laterally through the vertically arranged gear cover plates.

[0011] The cartridge medicine bottle is placed horizontally above two connected support rollers. The surface of the support rollers is provided with rubber ring grooves, and a support rubber ring that contacts the cartridge medicine bottle is embedded in the rubber ring grooves.

[0012] One end of the support roller extends to connect with the V-shaped groove plate, and the upper surface of the V-shaped groove plate is provided with a V-shaped groove, in which the neck of the cartridge medicine is placed.

[0013] Preferably, the bottom of the base is provided with a dovetail guide rail slider groove, which is connected to the dovetail seat guide rail slider. The motor transmits torque through a miniature bellows coupling. The rotation of the drive gear drives the two driven gears to rotate, thereby driving the support roller to rotate.

[0014] Preferably, the gearbox has a positioning pin hole at the bottom, which positions the gearbox on a protrusion on one side of the base. The bottom surface of the gearbox is connected to the protrusion on one side of the base by screws. The gear cover plate has a positioning pin hole and a screw through hole at the top. The top of the gear cover plate is positioned to the gearbox by a first positioning pin and connected by screws.

[0015] Preferably, the bottom of the V-groove plate is provided with a positioning pin hole and a threaded hole, and the V-groove plate is positioned with the base by a first positioning pin and connected by screws.

[0016] Preferably, the base, gear cover, V-groove plate, and gearbox are all made of polyoxymethylene material.

[0017] Compared with the prior art, the beneficial effects of this utility model are as follows: The motor transmits torque through a miniature bellows coupling. The rotation of the driving gear drives the two driven gears to rotate, which in turn drives the support roller to rotate. The rotation of the support roller causes the cartridge medicine bottle to rotate smoothly. The cartridge medicine bottle is placed on the support rubber ring, and the neck of the cartridge medicine bottle is stuck in the V-groove, so that the cartridge medicine bottle cannot move axially when rotating. This utility model adopts a dovetail guide rail slider for installation and a miniature bellows coupling for connection with the motor, which makes installation and replacement convenient, requires less professional skills from the testing personnel, and can ensure the installation accuracy requirements, making the product run stably. This utility model has a compact structure, is easy to assemble, and is simple to operate. All the processed parts and the parts near the electrodes are made of insulating materials to avoid abnormal test results due to material properties. This utility model can be adapted to a variety of different types and specifications of medicines and has strong inclusiveness. Attached Figure Description

[0018] Fig. 1 This is an exploded view of the overall structure of this utility model;

[0019] Fig. 2 This is a cross-sectional view of the overall structure of this utility model.

[0020] In the diagram: 1. Base; 2. Gear cover plate; 3. V-groove plate; 4. Gearbox; 5. Support roller; 6. Dovetail guide rail slider; 7. Drive gear; 8. Driven gear; 9. Miniature bellows coupling; 10. Drive shaft; 11. Support rubber ring; 12. Positioning pin; 13. Gear groove; 14. Dovetail guide rail slider groove; 15. V-groove; 16. Bottle neck of the cartridge medicine bottle; 17. Rubber ring slot. Detailed Implementation

[0021] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0022] In the description of this utility model, it should be noted that the terms "vertical", "up", "down", "horizontal", etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings. They are only for the convenience of describing this utility model and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on this utility model.

[0023] In the description of this utility model, it should also be noted that, unless otherwise explicitly specified and limited, the terms "set," "install," "connect," and "link" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; and they can refer to the internal connection of two components. Those skilled in the art can understand the specific meaning of the above terms in this utility model according to the specific circumstances.

[0024] Please see Figs. 1-2 This utility model provides a technical solution: a high-voltage discharge test bracket for cartridge medicine, including a drive shaft 10, a gearbox 4 connected to the drive shaft 10, and a gear cover plate 2 and a V-groove plate 3 connected through a base 1;

[0025] The gearbox 4 has a gear groove 13 on one side, and the gear groove 13 has two support roller holes and a main shaft through hole. One end of the drive shaft 10 is connected to the miniature bellows coupling 9. The miniature bellows coupling 9 passes through the through hole at the upper end of the gearbox 4 and is connected to the drive gear 7. The drive gear 7 is located at the main shaft through hole. The bottom sides of the drive gear 7 are respectively engaged with the corresponding driven gears 8, and the driven gears 8 are located at the corresponding support roller holes. The driven gears 8 are respectively connected to the support rollers 5 that pass laterally through the vertically arranged gear cover plates 2.

[0026] The cartridge medicine bottle is placed horizontally above two connected support rollers 5. The surface of the support rollers 5 is provided with rubber ring grooves 17, and a support rubber ring 11 that contacts the cartridge medicine bottle is embedded inside the rubber ring grooves 17. When the support rollers 5 rotate, they drive the cartridge medicine bottle to rotate smoothly.

[0027] One end of the support roller 5 extends to connect with the V-shaped groove plate 3. The upper surface of the V-shaped groove plate 3 is provided with a V-shaped groove 15, and the neck 16 of the cartridge medicine bottle is placed inside the V-shaped groove 15.

[0028] Furthermore, the bottom of the base 1 is provided with a dovetail guide rail slider groove 14, which is connected to the dovetail seat guide rail slider 6, making it convenient to replace different models of brackets.

[0029] The motor transmits torque through the miniature bellows coupling 9. The rotation of the driving gear 7 drives the two driven gears 8 to rotate, which in turn drives the support roller 5 to rotate. The use of gear transmission structure makes the structure compact, the transmission relatively accurate, the efficiency high, the structure compact, the operation reliable, and the service life long.

[0030] Furthermore, the bottom of the gearbox 4 is provided with a positioning pin hole, and the positioning pin 12 positions the gearbox 4 on the protrusion on one side of the base 1. The bottom surface of the gearbox 4 is connected to the protrusion on one side of the base 1 by screws. The top of the gear cover plate 2 is provided with a positioning pin hole and a screw through hole. The top of the gear cover plate 2 is positioned to the gearbox 4 by the first positioning pin and connected by screws.

[0031] Furthermore, the bottom of the V-groove plate 3 is provided with a positioning pin hole and a threaded hole. The V-groove plate 3 is positioned with the base 1 by the first positioning pin and connected by screws.

[0032] The positions of the gearbox 4 and the V-groove plate 3 relative to the base 1 can be located by using the locating pin hole and the threaded hole, thereby constraining the span between the gear cover plate 2 and the V-groove plate 3.

[0033] Furthermore, the base 1, gear cover plate 2, V-groove plate 3, and gearbox 4 are all made of POM (polyoxymethylene) material. Due to its high strength, rigidity, good elasticity, excellent wear resistance, and good self-lubricating properties, it greatly simplifies the structure. At the same time, POM is an insulating material, making it very suitable for this working condition.

[0034] Working principle:

[0035] The motor transmits torque through a miniature bellows coupling 9. The rotation of the driving gear 7 drives the two driven gears 8, which in turn drive the support roller 5. The rotation of the support roller 5 causes the cartridge medicine bottle to rotate smoothly. The cartridge medicine bottle is placed on the support rubber ring 11, and the neck 16 of the cartridge medicine bottle is locked in the V-groove 15, preventing axial movement of the cartridge medicine bottle during rotation. It is positioned at a fixed height on the support roller 5 and rotates at a certain speed. At the same time, the V-groove plate 3 prevents axial movement of the cartridge bottle. This utility model is applicable to the PTI E-Scan 655 micro-current high-voltage discharge offline tester. This utility model is installed after the PTI E-Scan 655 tester. The specific installation method is not described here. It can achieve accurate height positioning of the medicine, smooth rotation of the medicine, and no axial movement, resulting in stable test results. This utility model uses a dovetail guide rail slider 6 for installation and a miniature bellows coupling 9 for connection with the motor, making installation and replacement convenient, requiring less professional expertise from the testing personnel, while ensuring installation accuracy and stable product operation.

[0036] This invention features a compact structure, easy assembly, and simple operation. All machined parts and areas near the electrodes are made of insulating materials to prevent abnormal test results due to material properties. This invention is adaptable to various types and specifications of pharmaceuticals, demonstrating strong versatility.

[0037] Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the present invention, the scope of which is defined by the appended claims and their equivalents.

Claims

1. A high-voltage discharge test bracket for cartridge-type medicines, characterized in that: Includes a drive shaft (10), a gearbox (4) that is inserted into the drive shaft (10), and a gear cover plate (2) and a V-groove plate (3) connected by a base (1); The gearbox (4) has a gear groove (13) on one side, and the gear groove (13) has two support roller holes and a main shaft through hole. One end of the drive shaft (10) is connected to the miniature bellows coupling (9). The miniature bellows coupling (9) passes through the through hole at the top of the gearbox (4) and is connected to the drive gear (7). The drive gear (7) is located at the main shaft through hole. The bottom sides of the drive gear (7) are respectively meshed with the corresponding driven gears (8), and the driven gears (8) are located at the corresponding support roller holes. The driven gears (8) are respectively connected to the support rollers (5) that pass through the vertically arranged gear cover plates (2) laterally. The cartridge medicine bottle is placed horizontally above two connected support rollers (5). The surface of the support rollers (5) is provided with rubber ring grooves (17), and the rubber ring grooves (17) are inlaid with support rubber rings (11) that are in contact with the cartridge medicine bottle. One end of the support roller (5) extends to connect with the V-groove plate (3), and the upper surface of the V-groove plate (3) is provided with a V-groove (15), and the neck (16) of the cartridge medicine bottle is placed inside the V-groove (15).

2. The high-voltage discharge test bracket for cartridge-type medicines according to claim 1, characterized in that: The base (1) has a dovetail guide rail slider groove (14) at the bottom. The dovetail guide rail slider groove (14) is connected to the dovetail seat guide rail slider (6). The motor transmits torque through the miniature bellows coupling (9). The drive gear (7) rotates and drives the two driven gears (8) to rotate, which in turn drives the support roller (5) to rotate.

3. The high-voltage discharge test bracket for cartridge-type medicines according to claim 1, characterized in that: The gearbox (4) has a positioning pin hole at the bottom. The positioning pin (12) positions the gearbox (4) on the protrusion on one side of the base (1). The bottom surface of the gearbox (4) is connected to the protrusion on one side of the base (1) by screws. The gear cover plate (2) has a positioning pin hole and a screw through hole at the top. The top of the gear cover plate (2) is positioned to the gearbox (4) by the first positioning pin and connected by screws.

4. The high-voltage discharge test bracket for cartridge-type medicines according to claim 1, characterized in that: The bottom of the V-groove plate (3) is provided with a positioning pin hole and a threaded hole. The V-groove plate (3) and the base (1) are positioned by the first positioning pin and connected by screws.

5. The high-voltage discharge test bracket for cartridge-type medicines according to claim 1, characterized in that: The base (1), gear cover plate (2), V-groove plate (3), and gearbox (4) are all made of polyoxymethylene material.

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