Penicillin bottle for freeze-dried medicine

By incorporating reinforcing ribs and flow channels at the body and neck of the vial, combined with an arc-shaped bottom and raised strip design, the problem of cracking caused by thermal expansion and contraction during freeze-drying is solved, improving drug quality and production efficiency while reducing energy consumption and management costs.

CN223914414UActive Publication Date: 2026-02-17TIANJIN HANRUI PHARMA +1
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Patent Information

Application Number
CN202422999858.5
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-12-06
Publication Date
2026-02-17
Estimated Expiration
2034-12-06

AI Technical Summary

Technical Problem

Traditional freeze-dried powder vials have an increased risk of breakage due to thermal expansion and contraction during the freeze-drying process, which affects drug quality and safety and increases production costs.

Method used

The vial features a reinforcing rib at the junction of the vial body and neck, employing a right-angled triangular structure. The outer wall of the vial body has a flow guide groove, and the bottom is designed as an arc with a raised strip at the bottom to enhance structural strength and distribute heat evenly.

Benefits of technology

It significantly reduces the risk of cracking due to thermal expansion and contraction during freeze-drying, improves the consistency of drug quality and production efficiency, reduces energy consumption, and improves the accuracy of drug management.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model provides a penicillin bottle for freeze-drying medicine, which comprises a bottle body, and the bottle body comprises a bottle bottom, a bottle body, a bottle neck and a bottle opening which are arranged from bottom to top; a reinforcing rib is integrally formed at the joint of the bottle body and the bottle neck; a flow guide groove is formed in the outer side wall of the bottle body; a raised line is integrally formed at the bottom of the bottle bottom; according to the freeze-drying bottle, the reinforcing ribs are arranged at the joint of the bottle body and the bottle neck, and the right triangle structure is adopted, so that the structural strength of the bottle body is remarkably enhanced, and the risk of breakage caused by thermal expansion and cold contraction in the freeze-drying process is reduced; in addition, the surface area of the bottle wall of the bottle body is increased, conduction paths of heat on the bottle wall are increased, uniform heating is facilitated, and meanwhile the grooves can disperse stress borne by the bottle body to a certain degree.
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Description

TECHNICAL FIELD

[0001] The utility model relates to the field of a penicillin bottle, especially to a penicillin bottle for lyophilized medicine. BACKGROUND

[0002] Lyophilized powder is a solid drug form prepared by freeze-drying technology, widely used in the field of biological medicine, especially suitable for beta-lactam, aminoglycoside and macrolide antibiotics. Freeze-drying technology can avoid drug oxidation or high-temperature decomposition, so that the drug is usually in the form of a sponge block or loose crystal, which can be quickly dissolved after adding water, and is beneficial to the long-term storage of unstable drugs and convenient for transportation. The penicillin bottle, as a common pharmaceutical packaging container, is widely used for packaging lyophilized powder due to its good sealing performance, transparency and mechanical strength.

[0003] The traditional lyophilized powder penicillin bottle has a relatively simple design, mainly focusing on the capacity, sealing performance and material selection of the bottle body. However, with the continuous development of lyophilization technology and the increasing demand for drug quality, the design of traditional penicillin bottles gradually exposes some problems. For example, the risk of bottle body rupture due to thermal expansion and contraction during the lyophilization process increases, which not only affects the quality and safety of the drug, but also increases the production cost. SUMMARY

[0004] To solve the problem of increased risk of bottle body rupture due to thermal expansion and contraction during the lyophilization process in the prior art, the utility model provides a penicillin bottle for lyophilized medicine;

[0005] The utility model provides a penicillin bottle for lyophilized medicine adopts the following technical scheme:

[0006] A penicillin bottle for lyophilized medicine, comprising a bottle body, the bottle body comprises a bottle bottom, a bottle body, a bottle neck and a bottle mouth arranged from bottom to top; a reinforcing rib is integrally formed at the junction of the bottle body and the bottle neck; a flow guide groove is formed on the outer side wall of the bottle body; a protruding strip is integrally formed at the bottom of the bottle bottom;

[0007] Further, the number of reinforcing ribs is N, N≥2; the reinforcing rib has a overall right triangle structure;

[0008] Further, the number of flow guide grooves is M, M≥2; the flow guide grooves are all vertically arranged on the outer side wall of the bottle body;

[0009] Further, the depth of the flow guide groove is 0.2mm-0.5mm, and the width of the flow guide groove is 0.5mm-1mm;

[0010] Further, the protruding strip is provided with a plurality of protruding strips, the plurality of protruding strips are concentric annular protrusions, and the height of the protruding strip is 0.1mm-0.3mm;

[0011] Further, the center portion of the bottle bottom inside the bottle body is convex to form an arc shape, and the curvature of the center portion to the edge portion inside the bottle bottom gradually decreases;

[0012] Further, the thickness of the bottle body gradually decreases from the bottom upward;

[0013] Further, the outer side wall of the bottle body is provided with a flow guide groove to form a smooth surface, which is set as a labeling area for attaching a corresponding label of the medicine.

[0014] In summary, the beneficial effects of the present application are:

[0015] The present application sets a reinforcing rib at the joint of the bottle body and the bottle neck, and adopts a right-angled triangular structure, which significantly enhances the structural strength of the bottle body and reduces the risk of rupture caused by thermal expansion and contraction during the freeze-drying process. In addition, the surface area of the bottle wall is increased, which increases the conduction path of heat on the bottle wall, helps to evenly heat, and the groove can also disperse the stress on the bottle body to a certain extent.

[0016] Secondly, the present application adopts an arc-shaped design for the bottle bottom, and the center portion is convex inward, which is beneficial to the uniform distribution of heat and reduces the quality difference of the medicine caused by uneven temperature. At the same time, the convex strip is also helpful to the uniform distribution and transmission of heat. BRIEF DESCRIPTION OF DRAWINGS

[0017] Figure 1 It is a schematic diagram of the overall structure of the present application;

[0018] Figure 2 It is a schematic diagram of the bottle bottom part of the overall structure of the present application;

[0019] Figure 3 It is a schematic diagram of the internal structure of the bottle body of the present application.

[0020] As shown in the figure: 1-bottle body, 2-bottle bottom, 3-bottle neck, 4-bottle mouth, 5-reinforcing rib, 6-flow guide groove, 7-convex strip, 8-labeling area. DETAILED DESCRIPTION

[0021] The following will be combined with the Figures 1-3 Further detailed description of the present application:

[0022] The present application discloses a kind of penicillin bottle for freeze-dried medicine, as shown in the figure: Figure 1 、 2 A kind of penicillin bottle for freeze-dried medicine, including bottle body, bottle body includes from bottom to top bottle bottom 2, bottle body 1, bottle neck 3, bottle mouth 4;The joint of bottle body 1 and bottle neck 3 is integrally formed with reinforcing rib 5;The outer side wall of bottle body 1 is provided with flow guide groove 6;The bottom of bottle bottom 2 is integrally formed with convex strip 7;

[0023] As shown in Figure 1 , 2 , the number of reinforcing ribs 5 is N, N≥2; the reinforcing ribs 5 are in the shape of a right triangle as a whole; in this embodiment, the reinforcing ribs 5 are located at the junction of the bottle body 1 and the bottle neck 3, and the strength of this area is improved by increasing the material thickness and changing the shape to prevent breakage caused by thermal expansion and contraction during the freeze-drying process; the design of the right triangle structure can more effectively disperse stress; the arrangement of the reinforcing ribs 5 significantly enhances the structural strength of the bottle, especially the weak area where the bottle neck 3 connects to the bottle body 1, reducing the risk of breakage, and the right triangle structure can more effectively resist external forces, improving the durability of the bottle;

[0024] As shown in Figure 1 , 2 , the number of flow guide grooves 6 is M, M≥2; the flow guide grooves 6 are all vertically arranged on the outer side wall of the bottle body 1; the depth of the flow guide grooves 6 is 0.2mm-0.5mm, and the width of the flow guide grooves 6 is 0.5mm-1mm; in this embodiment, these flow guide grooves 6 can increase the surface area of the bottle wall, increase the conduction path of heat on the bottle wall, and help to evenly heat, and the grooves can also disperse the stress on the bottle body 1 to some extent;

[0025] As shown in Figure 1 , 2 , the convex strips 7 are arranged in several strips, and the several convex strips 7 are concentric annular protrusions, with a height of 0.1mm-0.3mm; in this embodiment, these protrusions can form a small air gap when the vial is placed on the freeze-drying tray, which is conducive to the uniform transfer of heat from all directions to the bottle bottom 2, avoiding local overheating; at the same time, the convex strips 7 are arranged at the bottom of the bottle bottom 2, which can also prevent the bottle from sliding in the freeze-drying machine by increasing the friction with the contact surface;

[0026] As shown in Figure 3 , the bottle bottom 2 is raised inward to form an arc at the center of the inner part of the bottle body 1, and the curvature of the arc gradually decreases from the center to the edge of the inner part of the bottle bottom 2; the thickness of the bottle body 1 gradually decreases from the bottom upwards; in this embodiment, the inwardly raised arc at the center of the inner part of the bottle bottom 2 is conducive to the uniform distribution of heat during the freeze-drying process, reducing the differences in drug quality caused by uneven temperature; the gradually decreasing curvature from the center to the edge allows heat to spread more effectively from the center to the periphery, ensuring the uniformity of the freeze-drying effect and improving the quality of the drug; and the thickness of the bottle body 1 gradually decreases from the bottom upwards, ensuring the strength and stability of the bottle bottom 2, reducing the overall weight, ensuring the integrity of the bottle structure while achieving lightweight, improving production efficiency, and reducing energy consumption;

[0027] As shown in Figure 1 , 2As shown, the outer wall partition of the bottle body 1 has a flow channel 6 forming a smooth surface, which is set as a labeling area 8 for attaching the corresponding drug label. In this embodiment, by forming a smooth surface in the flow channel 6 on the outer wall partition of the bottle body 1 as the labeling area 8, it is convenient to attach the corresponding drug label without affecting the function of the flow channel 6. The labeling area 8 facilitates the identification and tracking of drug information, improving the efficiency and accuracy of drug management. At the same time, the smooth surface design ensures the label's firmness and readability, reducing errors caused by label detachment or blurring.

[0028] The foregoing has shown and described the basic principles, main features, and advantages of this utility model. The various components mentioned in this utility model are common technologies in the existing field. Those skilled in the art should understand that this utility model is not limited to the above embodiments. The embodiments and descriptions in the specification are merely illustrative of the principles of this utility model. Various changes and modifications can be made to this utility model without departing from its spirit and scope, and all such changes and modifications fall within the scope of the claims. The scope of protection of this utility model is defined by the appended claims and their equivalents.

Claims

1. A vial for lyophilized pharmaceuticals, comprising a vial body, characterized in that, The bottle body includes a bottle bottom (2), a bottle body (1), a bottle neck (3), and a bottle mouth (4) arranged from bottom to top; a reinforcing rib (5) is integrally formed at the connection between the bottle body (1) and the bottle neck (3); a flow guide groove (6) is provided on the outer side wall of the bottle body (1); and a raised strip (7) is integrally formed at the bottom of the bottle bottom (2).

2. A lyophilized pharmaceutical vial according to claim 1, characterized in that... The number of the reinforcing ribs (5) is N, where N≥2; the reinforcing ribs (5) are in the form of a right-angled triangle.

3. A lyophilized pharmaceutical vial according to claim 1, characterized in that... The number of the flow guide grooves (6) is M, where M≥2; the flow guide grooves (6) are all vertically arranged on the outer side wall of the bottle body (1).

4. A lyophilized pharmaceutical vial according to claim 3, characterized in that... The depth of the guide groove (6) is 0.2mm-0.5mm, and the width of the guide groove (6) is 0.5mm-1mm.

5. A lyophilized pharmaceutical vial according to claim 1, characterized in that... The convex strip (7) is provided in a plurality of strips, and the plurality of convex strips (7) are concentric annular protrusions, and the height of the convex strip (7) is 0.1mm-0.3mm.

6. A lyophilized pharmaceutical vial according to claim 1, characterized in that... The bottom (2) of the bottle protrudes inward to form an arc shape in the center of the part inside the bottle body (1), and the curvature of the arc from the center to the edge of the bottom (2) gradually decreases.

7. A lyophilized pharmaceutical vial according to claim 6, characterized in that... The thickness of the bottle body (1) gradually decreases from the bottom upwards.

8. A lyophilized pharmaceutical vial according to claim 1, characterized in that... The outer wall partition of the bottle body (1) has a flow guide groove (6) to form a smooth surface, which is set as a labeling area (8) for attaching the corresponding drug label.