Artery blood vessel wall mechanical property experiment device capable of simulating physiological environment conditions

Abstract

The utility model relates to an artery blood vessel wall mechanical property experiment device capable of simulating physiological environment conditions. Comprising a heat preservation table, a liquid inlet pipe, a liquid outlet pipe, a driving assembly, a pressure pump, a constant-pressure tank, an inflation bag and a controller. A base is arranged on one side of the heat preservation table, a pull rod is fixedly installed on the base, a tension sensor is arranged on the pull rod, and a liquid outlet pipe is arranged at the free end of the pull rod; a liquid inlet pipe is mounted in the testing groove and is connected with the driving assembly; the upper end of the liquid inlet pipe is connected with a pressure pump, an electromagnetic valve and a pressure sensor are arranged on the liquid guide pipe, and the pressure pump is connected with a pss solution box through a pipeline; the liquid outlet pipe is connected with the constant-pressure tank; the constant-pressure tank is also connected with the inflatable bag; according to the device, the change of the diameter and the axial length of the blood vessel test piece can be recorded in real time through the CCD camera when the internal pressure of the blood vessel test piece is changed or the blood vessel test piece is pulled, and the change is converted to the display screen to be displayed, so that a worker can conveniently monitor the deformation of the blood vessel test piece.

Description

Technical Field

[0001] This application relates to the field of vascular testing technology, and in particular to an experimental device for simulating the mechanical properties of arterial walls under physiological environmental conditions. Background Technology

[0002] The circulatory system is fundamental to human survival, providing the energy transport link for the body's activities. Preventing and treating cardiovascular diseases is of paramount importance. The cardiovascular system is a mechanically driven system centered on the heart. During blood circulation, blood flow, the deformation of blood cells and blood vessels, and the interaction between blood and blood vessels all follow mechanical laws. The use of cardiovascular treatment equipment is also influenced by internal and external factors, among which mechanical factors have a direct and significant effect.

[0003] There are many studies on the mechanical properties of arterial walls, but they are mostly tests of the ultimate tensile or ultimate expansion of blood vessels in an isolated state, that is, tests the maximum amount of tension or the maximum pressure that blood vessels can withstand. There is a lack of research on the mechanical properties of blood vessel walls under physiological environmental conditions (including temperature conditions and solution ionic conditions) and the impact of changes in physiological environmental conditions on the mechanical properties of blood vessel walls. Summary of the Invention

[0004] To address or partially address the problems existing in related technologies, this application provides an experimental device for simulating the mechanical properties of arterial walls under physiological environmental conditions, aiming to provide a device for studying the mechanical properties of blood vessel walls under physiological conditions or when the physiological environment changes.

[0005] Therefore, this application provides an experimental device for simulating the mechanical properties of arterial walls under physiological environmental conditions, including a warming platform, an inlet pipe, an outlet pipe, a drive assembly, a pressure pump, a constant pressure tank, an inflatable bladder, and a controller.

[0006] The heat preservation platform is equipped with a test tank. A base is provided on one side of the test tank. A pull rod is fixedly installed on the base. A tension sensor for detecting the magnitude of the tension force on the pull rod is provided. The free end of the pull rod extends to the top of the test tank and is provided with a liquid outlet pipe.

[0007] The test tank is equipped with an inlet pipe that is opposite to the outlet pipe. The inlet pipe is driven to move closer to or away from the outlet pipe by a drive assembly installed on the heat preservation platform.

[0008] The upper end of the inlet pipe is connected to the pressure pump via a guide pipe. The guide pipe is equipped with a solenoid valve and a pressure sensor. The pressure pump is connected to the PSS solution tank via a pipe. The outlet pipe is connected to the bottom of the constant pressure tank. The top of the constant pressure tank is connected to an inflatable bladder via a pipe.

[0009] A CCD camera is installed above the test tank. The CCD camera, the tensile sensor, and the pressure sensor are electrically connected to the signal input terminal of the controller. The signal output terminal of the controller is electrically connected to the solenoid valve, the pressure pump, and the display.

[0010] In some embodiments, the drive assembly includes a fixed platform, a worm gear, a worm, and a threaded rod;

[0011] A worm gear is rotatably mounted on the fixed platform via a rotating shaft, and a worm is rotatably mounted below the worm gear to mesh with it; the rotating shaft is a hollow shaft, and its inner wall is threaded.

[0012] The threaded rod is provided with a limiting plane. One end of the threaded rod passes through the fixed platform and is threadedly connected to the rotating shaft. The other end extends to the top of the test tank and is connected to the liquid inlet pipe.

[0013] In some designs, the inlet pipe is slidably connected to the threaded rod, allowing the inlet pipe to move up and down.

[0014] The liquid outlet pipe is slidably connected to the pull rod, allowing the liquid outlet pipe to move up and down.

[0015] In some designs, the inlet pipe is hinged to the threaded rod;

[0016] The liquid outlet pipe is hinged to the pull rod.

[0017] In some designs, the insulation platform has a heating chamber, and a partition is provided inside the insulation platform to divide the heating chamber into a first chamber and a second chamber that are interconnected. A heater is provided in the first chamber, and an impeller is rotatably installed in the second chamber. The impeller is driven to rotate by a motor.

[0018] The technical solution provided in this application may include the following beneficial effects:

[0019] This device can record in real time the changes in the diameter and axial length of the blood vessel specimen when the internal pressure changes or when it is subjected to tension using a CCD camera, and then display the data on the screen to facilitate the monitoring of the deformation of the blood vessel specimen by the staff.

[0020] It should be understood that the above general description and the following detailed description are exemplary and explanatory only, and do not limit this application. Attached Figure Description

[0021] The above and other objects, features and advantages of this application will become more apparent from the more detailed description of exemplary embodiments thereof in conjunction with the accompanying drawings, wherein the same reference numerals generally represent the same components in the exemplary embodiments thereof.

[0022] Figure 1 This is a schematic diagram of the structure of the testing device shown in the embodiments of this application;

[0023] Figure 2 This is a schematic diagram of the structure of the driving component of the testing device shown in the embodiments of this application;

[0024] Figure 3 This is a schematic diagram of the structure of the heat preservation platform of the testing device shown in the embodiments of this application.

[0025] Figure label:

[0026] 1. Insulation platform; 101. Test tank; 102. Base; 103. Tensile sensor; 104. Heating chamber; 105. Baffle; 106. Heater; 107. Impeller; 2. Inlet pipe; 3. Outlet pipe; 4. Drive assembly; 401. Fixed platform; 402. Worm gear; 403. Worm; 404. Threaded rod; 5. Pressure pump; 6. Constant pressure tank; 7. Inflatable bladder; 8. Liquid guide pipe; 9. PSS solution tank; 10. CCD camera. Detailed Implementation

[0027] Embodiments of this application will now be described in more detail with reference to the accompanying drawings. While embodiments of this application are shown in the drawings, it should be understood that this application may be implemented in various forms and should not be limited to the embodiments set forth herein. Rather, these embodiments are provided to make this application more thorough and complete, and to fully convey the scope of this application to those skilled in the art.

[0028] It should be understood that although the terms "first," "second," "third," etc., may be used in this application to describe various information, this information should not be limited to these terms. These terms are only used to distinguish information of the same type from one another. For example, without departing from the scope of this application, first information may also be referred to as second information, and similarly, second information may also be referred to as first information. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of that feature. In the description of this application, "multiple" means two or more, unless otherwise explicitly specified.

[0029] In the description of this application, it should be understood that the terms "length", "width", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings, and are only for the convenience of describing this application and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of this application.

[0030] Unless otherwise expressly specified and limited, the terms "installation," "connection," "linking," and "fixing," etc., should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral part; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; they can refer to the internal communication of two components or the interaction between two components. Those skilled in the art can understand the specific meaning of the above terms in this application according to the specific circumstances.

[0031] Please see Figure 1 This application provides an experimental device for simulating the mechanical properties of arterial walls under physiological environmental conditions, including a heating platform 1, an inlet pipe 2, an outlet pipe 3, a drive assembly 4, a pressure pump 5, a constant pressure tank 6, an inflatable bladder 7, and a controller.

[0032] The heating platform 1 has a test tank 101, which is used to hold physiological saline or physiological simulation fluid. A base 102 is provided on one side of the test tank 101. A pull rod is fixedly installed on the base 102. A tension sensor 103 is provided on the pull rod to detect the magnitude of the tension it receives. The free end of the pull rod extends to the top of the test tank 101 and is provided with an outlet pipe 3. The outlet pipe 3 is L-shaped and the horizontal end is located inside the test tank 101.

[0033] The test tank 101 is equipped with an inlet pipe 2, which is opposite to the outlet pipe 3. The inlet pipe 2 is L-shaped, with its horizontal section located inside the test tank 101. The inlet pipe 2 is driven to move closer to or away from the outlet pipe 3 by a drive assembly 4 installed on the heat preservation platform 1. The upper end of the inlet pipe 2 is connected to the pressure pump 5 through a guide pipe 8. The guide pipe 8 is equipped with a solenoid valve and a pressure sensor. The pressure pump 5 is connected to the PSS solution tank 9 through a pipe. The outlet pipe 3 is connected to the bottom of the constant pressure tank 6. The top of the constant pressure tank 6 is connected to an inflation bladder 7 through a pipe. In the initial state, the constant pressure tank 6 is filled with a mixture of 95% oxygen and 5% carbon dioxide.

[0034] A CCD camera 10 is installed above the test tank 101. The CCD camera 10, the tension sensor 103, and the pressure sensor are electrically connected to the signal input terminal of the controller. The signal output terminal of the controller is electrically connected to the solenoid valve, the pressure pump 5, and the display.

[0035] During testing, test tank 101 is filled with physiological saline or physiological simulation solution, and PSS solution tank 9 is filled with PSS solution. The two ends of the vascular specimen are connected to the horizontal ends of the inlet pipe 2 and the outlet pipe 3, respectively, and are immersed in physiological saline or physiological simulation solution. Then, the controller activates pressure pump 5 to inject PSS solution into the vascular specimen and constant pressure tank 6. As the liquid level in constant pressure tank 6 rises, the liquid pressure inside the vascular specimen also rises accordingly. Pressure sensors detect the liquid pressure inside the vascular specimen in real time and transmit the data to the controller. When the set pressure is reached, the controller closes the solenoid valve, stopping pressure pump 5. During this process, CCD camera 10 takes real-time photos of the vascular specimen and analyzes them, obtaining the axial and diameter changes of the vascular specimen, which are then uploaded to the controller and displayed on a monitor for subsequent research.

[0036] Subsequently, staff can inject air or release some gas into the constant pressure tank 6 via the inflatable bladder 7 to change the liquid pressure inside the blood vessel specimen. Compared to directly changing the pressure by injecting more PSS solution through the pressure pump 5, this method provides more precise pressure regulation. During this process, deformation data is still collected by the CCD camera 10.

[0037] Furthermore, staff can stretch the blood vessel specimen using the drive component 4. During this process, the CCD camera 10 captures deformation data; the tension sensor 103 detects the tension on the blood vessel specimen in real time and forwards it to the display via the controller for subsequent research.

[0038] In some specific implementations, such as Figure 2 As shown, the drive assembly 4 includes a fixed platform 401, a worm gear 402, a worm 403, and a threaded rod 404. The worm gear 402 is rotatably mounted on the fixed platform 401 via a rotating shaft, and the worm 403 is rotatably mounted below the worm gear 402 and meshes with it. The rotating shaft is a hollow shaft with threads on its inner wall. The threaded rod 404 has a limiting plane, and the fixed platform 401 has a light hole that matches the threaded rod 404. One end of the threaded rod 404 passes through the light hole and is threadedly connected to the rotating shaft, while the other end extends to the top of the test tank 101 and is connected to the liquid inlet pipe 2. Due to the presence of the limiting plane, the threaded rod 404 can only slide horizontally along the light hole and cannot rotate.

[0039] When it is necessary to adjust the tension on the blood vessel specimen, the worm 403 is rotated, which in turn drives the rotating shaft to rotate through the worm wheel 402, thereby causing the threaded rod 404 to slide left and right. Through the large transmission ratio between the worm wheel 402 and the worm 403, and the further speed reduction between the rotating shaft and the threaded rod 404, the tension on the blood vessel specimen can be adjusted very precisely, making it more convenient to use.

[0040] In this embodiment, a handle may be provided at one end of the worm gear 403 to facilitate its rotation.

[0041] In some specific embodiments, the inlet pipe 2 is slidably connected to the threaded rod 404, so that the inlet pipe 2 can move up and down; specifically, a collar is provided at the end of the threaded rod 404, and the inlet pipe 2 is inserted into the collar, thereby forming a sliding connection. To prevent the inlet pipe 2 from coming out, a limiting block can also be provided on the inlet pipe 2.

[0042] The outlet pipe 3 is slidably connected to the pull rod, allowing the outlet pipe 3 to move up and down. Similarly, a sleeve is provided at the end of the pull rod, the outlet pipe 3 is inserted into the sleeve, and a limiting block is provided.

[0043] During the installation of the vascular specimen, the inlet tube 2 and outlet tube 3 can be pulled upwards out of the test slot 101, which facilitates the assembly of the vascular specimen with the inlet tube 2 or outlet tube 3.

[0044] In some specific embodiments, the inlet pipe 2 is hinged to the threaded rod 404; the outlet pipe 3 is hinged to the pull rod. During the installation of the blood vessel, the inlet pipe 2 and the outlet pipe 3 can be rotated out of the test slot 101, thereby facilitating the assembly of the blood vessel specimen with the inlet pipe 2 or the outlet pipe 3.

[0045] In some specific implementations, such as Figure 3 As shown, the heat preservation platform 1 has a heating chamber 104 inside. The heat preservation platform 1 is provided with a partition 105, which divides the heating chamber 104 into a first chamber and a second chamber that are interconnected. A heater 106 is provided in the first chamber, and an impeller 107 is rotatably installed in the second chamber. The impeller 107 is driven to rotate by a motor.

[0046] During operation, the heater 106 heats the heat-conducting medium in the first chamber, and then the motor drives the impeller 107 to rotate, thereby circulating the heat-conducting medium in the first and second chambers, and thus carrying the heat to different locations to achieve the purpose of heating the solution in the test tank 101. With this heating method, the solution in the test tank 101 experiences less fluctuation, which is beneficial for the CCD camera 10 to photograph the blood vessel specimen through the solution. Furthermore, the solution in the test tank 101 is heated more uniformly.

[0047] The various embodiments of this application have been described above. These descriptions are exemplary and not exhaustive, nor are they limited to the disclosed embodiments. Many modifications and variations will be apparent to those skilled in the art without departing from the scope and spirit of the described embodiments. The terminology used herein is chosen to best explain the principles, practical application, or improvement of the technology in the market, or to enable others skilled in the art to understand the embodiments disclosed herein.

Claims

1. An experimental device for simulating the mechanical properties of arterial walls under physiological environmental conditions, characterized in that: Includes a heat preservation platform, inlet pipe, outlet pipe, drive assembly, pressure pump, constant pressure tank, inflatable bladder, and controller; The heat preservation platform is equipped with a test tank. A base is provided on one side of the test tank. A pull rod is fixedly installed on the base. A tension sensor for detecting the magnitude of the tension force on the pull rod is provided. The free end of the pull rod extends to the top of the test tank and is provided with a liquid outlet pipe. The test tank is equipped with an inlet pipe that is positioned opposite to the outlet pipe. The inlet pipe is driven to move closer to or away from the outlet pipe by a drive assembly installed on the heat preservation platform. The upper end of the inlet pipe is connected to the pressure pump via a guide pipe. The guide pipe is equipped with a solenoid valve and a pressure sensor. The pressure pump is connected to the PSS solution tank via a pipe. The outlet pipe is connected to the bottom of the constant pressure tank. The top of the constant pressure tank is connected to an inflatable bladder via a pipe. A CCD camera is installed above the test tank. The CCD camera, the tensile sensor, and the pressure sensor are electrically connected to the signal input terminal of the controller. The signal output terminal of the controller is electrically connected to the solenoid valve, the pressure pump, and the display.

2. The experimental device for simulating the mechanical properties of arterial walls under physiological environmental conditions according to claim 1, characterized in that: The drive assembly includes a fixed platform, a worm gear, a worm, and a threaded rod; A worm gear is rotatably mounted on the fixed platform via a rotating shaft, and a worm is rotatably mounted below the worm gear to mesh with it; the rotating shaft is a hollow shaft, and its inner wall is threaded. The threaded rod is provided with a limiting plane. One end of the threaded rod passes through the fixed platform and is threadedly connected to the rotating shaft. The other end extends to the top of the test tank and is connected to the liquid inlet pipe.

3. The experimental device for simulating the mechanical properties of arterial walls under physiological environmental conditions according to claim 2, characterized in that: The inlet pipe is slidably connected to the threaded rod, allowing the inlet pipe to move up and down. The liquid outlet pipe is slidably connected to the pull rod, allowing the liquid outlet pipe to move up and down.

4. The experimental device for simulating the mechanical properties of arterial walls under physiological environmental conditions according to claim 2, characterized in that: The inlet pipe is hinged to the threaded rod; The liquid outlet pipe is hinged to the pull rod.

5. The experimental device for simulating the mechanical properties of arterial walls under physiological environmental conditions according to claim 1, characterized in that: The heat preservation platform has a heating chamber inside, and a partition is provided inside the heat preservation platform to divide the heating chamber into a first chamber and a second chamber that are interconnected. A heater is provided in the first chamber, and an impeller is rotatably installed in the second chamber. The impeller is driven to rotate by a motor.

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