Hemodialysis filter with blood perfusion adsorption function

By designing a hemodialysis filter that integrates hemodialysis and perfusion functions, the infection problem caused by series devices was solved, achieving safe and efficient blood treatment.

CN223944710UActive Publication Date: 2026-02-27CHINA JAPAN FRIENDSHIP HOSPITAL
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Patent Information

Application Number
CN202423146361.5
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-12-19
Publication Date
2026-02-27
Estimated Expiration
2034-12-19

AI Technical Summary

Technical Problem

In existing technologies, when hemodialysis machines and hemoperfusion machines are used in series, patients are prone to infection, which threatens their lives and reduces their quality of life.

Method used

Design a hemodialysis filter with blood perfusion adsorption function, comprising a filter, a dialysate interface, hollow fibers and adsorption particles. By combining hollow fibers and adsorption particles, hemodialysis and perfusion are integrated, reducing the risk of infection.

Benefits of technology

It enables a single device to perform hemodialysis and perfusion simultaneously, reducing the risk of infection, ensuring the stability of blood circulation, preventing adsorbed particles from entering the body, and reducing the risk of coagulation and blockage.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model discloses a hemodialysis filter with a blood perfusion adsorption function. The hemodialysis filter comprises a filter, two dialysate connectors, a plurality of hollow fiber filaments, two blood connectors and a plurality of adsorption particles. The two dialysate connectors are fixedly connected with the outer wall of the filter, the inner ends of the two dialysate connectors penetrate through the inner wall of the filter, and the dialysate connectors are used for conveying dialysate; the plurality of hollow fibers are mounted on the inner wall of the filter and are made of polyether sulfone membranes; the two blood interfaces are respectively connected in series with the two ends of the filter; the plurality of adsorption particles are mounted in the hollow fiber filaments which are far away from the blood connector and the dialysate connector and are 1 / 3-1 / 2 of the number of the hollow fiber filaments, and the adsorption particles are resin carbon soaked by heparin. According to the hemodialysis and perfusion combined device, the hemodialysis and perfusion functions can be simultaneously completed by a single device through the combination of the characteristics of the hemodialysis filter and the hemoperfusion device, so that the occurrence of infection of patients is reduced.
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Description

TECHNICAL FIELD

[0001] The utility model relates to medical supplies field especially is concerned with a hemodialysis filter with blood perfusion adsorption function. BACKGROUND

[0002] End-stage renal disease refers to the end stage of chronic glomerulonephritis, hypertensive nephropathy, diabetic nephropathy, tumor, immunological disease and polycystic kidney disease. Hemodialysis is one of the treatment methods for ESRD patients, which can complete the osmotic filtration exchange inside and outside the membrane through the use of artificial semi-permeable membrane in the dialyzer, and achieve the effect of maintaining the stability of the internal environment. However, the dialysis membrane can only allow small molecules to pass through, while macromolecular substances such as proteins cannot pass through. As a result, the macromolecular toxins in the patient's body deposit over time, causing various uncomfortable symptoms in the patient, including nausea, vomiting, and skin itching. Blood perfusion refers to a relatively new dialysis treatment mode performed by combining hemodialysis with a perfusion device. Through adsorption, it can more effectively remove macromolecular toxins, reduce the incidence of long-term complications such as skin itching and sleep disorders in patients undergoing maintenance hemodialysis, and improve the quality of life and survival rate. Currently, most of the hemodialysis combined with blood perfusion treatments performed on patients in clinical practice are to connect the hemodialysis device and the blood perfusion device in series for operation, treatment and nursing. However, patients receiving maintenance hemodialysis combined with blood perfusion using the method of connecting the hemodialysis device and the blood perfusion device in series for operation, treatment and nursing are prone to infection, thereby threatening the life safety of the patients and reducing the quality of life of the patients. Therefore, a hemodialysis filter with blood perfusion adsorption function is proposed. SUMMARY

[0003] The utility model solves the technical problem that patients receiving maintenance hemodialysis combined with blood perfusion using the method of connecting the hemodialysis device and the blood perfusion device in series for operation, treatment and nursing are prone to infection, thereby threatening the life safety of the patients and reducing the quality of life of the patients, and provides a hemodialysis filter with blood perfusion adsorption function.

[0004] The utility model adopts the technical scheme that

[0005] A hemodialysis filter with blood perfusion adsorption function, comprising a filter, two dialysate interfaces, a plurality of hollow fiber filaments, two blood interfaces, and a plurality of adsorption particles.

[0006] Both of the dialysate interfaces are fixedly connected with the outer wall of the filter, and the inner ends of both of the dialysate interfaces penetrate through the inner wall of the filter, wherein the dialysate interfaces are used for conveying dialysate.

[0007] The plurality of hollow fiber filaments are all installed on the inner wall of the filter, and the hollow fiber filaments are made of polyether sulfone membrane.

[0008] Two said blood interfaces are connected in series at two ends of the filter respectively;

[0009] A plurality of said adsorption particles are installed inside 1 / 3-1 / 2 number of hollow fiber filaments away from the blood interface and the dialysate interface, and the adsorption particles are heparin-soaked resin charcoal.

[0010] Preferably, a sealing rubber ring and a hemodialysis filter net are installed at both ends of the filter, and two groups of said sealing rubber rings and hemodialysis filter nets are respectively located at two ends of the plurality of hollow fiber filaments.

[0011] The beneficial effects of the present application are:

[0012] 1. The present application combines the characteristics of hemodialysis filter and blood perfusion device, so that a single device can complete the functions of hemodialysis and perfusion at the same time, thereby reducing the occurrence of patient infection;

[0013] 2. The present application reduces the amount of extracorporeal blood circulation of the patient, ensures the stability of the patient's blood circulation, and reduces the occurrence of hypotension and the like;

[0014] 3. The present application sets the sealing rubber ring and the hemodialysis filter net, which can prevent the adsorption particles from entering the body with blood circulation;

[0015] 4. The present application places the adsorption particles in 1 / 3-1 / 2 number of hollow fiber filaments away from the blood interface and the dialysate interface, which further ensures that the adsorption particles will not cause filter blockage and blood clotting;

[0016] 5. The present application soaks the hollow fiber filaments and the adsorption particles in a low osmotic solution containing sodium heparin, thereby maintaining the safety of the filter during treatment and reducing the occurrence of filter blockage such as blood clotting. BRIEF DESCRIPTION OF DRAWINGS

[0017] Fig. 1 is the overall structure diagram of the hemodialysis filter with blood perfusion adsorption function;

[0018] Fig. 2 is the hollow fiber filament structure diagram of the hemodialysis filter with blood perfusion adsorption function.

[0019] BRIEF DESCRIPTION OF DRAWINGS: 1, filter; 2, dialysate interface; 3, hollow fiber filament; 4, blood interface; 5, sealing rubber ring; 6, hemodialysis filter net; 7, adsorption particle. DETAILED DESCRIPTION

[0020] The concept and technical effects of the present application will be described below in conjunction with the embodiments to clearly and completely understand the purpose, features and effects of the present application.

[0021] As shown in the accompanying Figs. 1-2 The present application provides a hemodialysis filter with hemoperfusion adsorption function, comprising a filter 1, two dialysate interfaces 2, a plurality of hollow fiber filaments 3, two blood interfaces 4, a plurality of adsorption particles 7;

[0022] Both of the two dialysate interfaces 2 are fixedly connected with the outer wall of the filter 1, and the inner ends of the two dialysate interfaces 2 both penetrate to the inner wall of the filter 1, and the dialysate interface 2 is used for conveying dialysate;

[0023] The plurality of hollow fiber filaments 3 are all installed on the inner wall of the filter 1, the hollow fiber filaments 3 are made of polyether sulfone membrane, and the filter 1 is a wet membrane filter, that is, the hollow fiber filaments 3 and the adsorption particles 7 are soaked in a low osmotic solution, and the liquid contains heparin sodium injection, so as to keep the safety during the treatment of the filter 1 and reduce the occurrence of blockage such as blood coagulation of the filter 1;

[0024] The two blood interfaces 4 are connected in series at the two ends of the filter 1 respectively;

[0025] The plurality of adsorption particles 7 are installed inside the hollow fiber filaments 3 which are away from 1 / 3-1 / 2 of the number of the blood interfaces 4 and the dialysate interfaces, so as to prevent the excessive adsorption particles 7 from causing the internal blockage of the filter 1 and blood coagulation, the adsorption particles 7 are heparin-soaked resin charcoal, and additionally, activated carbon soaked with heparin can also be selected as the adsorption material;

[0026] The filter 1 is internally provided with a sealing rubber ring 5 and a hemodialysis filter net 6 at both ends, the two groups of sealing rubber rings 5 and the hemodialysis filter nets 6 are respectively located at the two ends of the plurality of hollow fiber filaments 3, and the hemodialysis filter net 6 only allows blood circulation, so as to prevent the adsorption particles 7 from entering the body with blood circulation.

[0027] Working principle: blood enters the inside of the filter 1 through the blood interface 4, and at the same time, the dialysate interface 2 is connected with the dialysate outside, so that the dialysate is conveyed into the inside of the filter 1, the blood flows through the plurality of hollow fiber filaments 3, and the adsorption particles 7 are used to adsorb macromolecular substances, and at the same time, the dialysate conveyed through the dialysate interface 2 is used to dialyze the blood, and the dialyzed blood is circulated into the human body through the other blood interface 4, so as to simultaneously complete the functions of hemodialysis and hemoperfusion.

[0028] The above embodiments are only part of the embodiments of the present application, but not all the embodiments, and other embodiments obtained by the person skilled in the art on the basis of the embodiments of the present application without creative labor all belong to the protection scope of the present application.

Claims

1. A hemodiafiltration device having a blood perfusion adsorption function, characterized by: The filter (1), two dialysate interfaces (2), a plurality of hollow fiber filaments (3), two blood interfaces (4), and a plurality of adsorption particles (7) are included. The two dialysate interfaces (2) are fixedly connected to the outer wall of the filter (1), and the inner ends of the two dialysate interfaces (2) penetrate the inner wall of the filter (1), and the dialysate interface (2) is used for conveying dialysate. The plurality of hollow fiber filaments (3) are installed on the inner wall of the filter (1), and the hollow fiber filaments (3) are made of polyether sulfone membrane. The two blood interfaces (4) are connected in series at the two ends of the filter (1). The plurality of adsorption particles (7) are installed inside 1 / 3-1 / 2 of the hollow fiber filaments (3) away from the blood interface (4) and the dialysate interface, and the adsorption particles (7) are heparin-soaked resin charcoal.

2. The hemodiafiltration device with blood perfusion adsorption function according to claim 1, characterized in that: The filter (1) is internally provided with a sealing rubber ring (5) and a hemodialysis filter net (6) at both ends, and the two groups of sealing rubber rings (5) and hemodialysis filter nets (6) are respectively located at both ends of the plurality of hollow fiber filaments (3).