Detection kit convenient to use

Abstract

The utility model provides a detection kit convenient to use. The kit comprises a first clamping shell and a second clamping shell, the first clamping shell comprises a sample adding hole, the second clamping shell comprises a test paper step and a sample injection cavity, one of the first clamping shell and the second clamping shell is provided with a test paper containing cavity, test paper is placed in the test paper containing cavity, one end of the test paper is fixed to the test paper step, and the other end of the test paper is fixed to the test paper containing cavity. A detector only needs to dropwise add a sample into the sample adding hole and then press or extrude the buffer solution cavity into the buffer solution hole, and does not need to extract the sample in advance and treat the sample, so that the tedious process and the error probability of diluting the outside of the sample card by the detector during detection are reduced, consumables are saved, and the operation is very convenient; a quantitative buffer solution is stored in the buffer solution cavity, so that the influence of too much or too little buffer solution dropwise added by a detector on the detection accuracy is reduced; the inclined surface of the test paper step enables the buffer solution to uniformly disperse and move upwards on the test paper, thereby improving the stability and accuracy of the detection reagent.

Description

TECHNICAL FIELD

[0001] The present application relates to the technical field of biomedical detection, in particular to a convenient detection kit. BACKGROUND

[0002] When performing micro-sample (such as whole blood, serum, plasma, urine) detection using in vitro diagnostic reagents, especially using an immunodetection card, the sample needs to be diluted and mixed outside the card before detection. The dilution process requires additional dilution containers and corresponding buffers, making the detection process more cumbersome. Especially when performing a large number of micro-sample detections, the probability of operator error is increased. If dilution is not performed outside the card, but sample is added first and then buffer is added in the only sample addition hole of the traditional detection card, too much or too little buffer will affect the sample uplink effect. The buffer will also cause the sample added first to complete the immune reaction, while the sample at the end of the sample pad cannot be chromatographed to complete the reaction, the actual sample amount for immune reaction is not enough, resulting in inaccurate detection results. SUMMARY

[0003] The purpose of the present application is to provide a convenient detection kit, which aims to solve the problems of cumbersome detection process and low accuracy of existing test paper.

[0004] A convenient detection kit, comprising:

[0005] A first card shell, provided with a sample addition hole;

[0006] A second card shell, provided with a test paper step and a sample inlet cavity;

[0007] One of the first card shell and the second card shell is provided with a test paper containing cavity, the test paper containing cavity is placed with test paper, one end of the test paper is fixed to the test paper step, and the other end is fixed to the test paper containing cavity.

[0008] Further, a buffer cavity fixedly connected with the kit is further included, the buffer cavity is located in the first card shell, the buffer cavity is oppositely arranged with the sample inlet cavity, and the thickness of the bottom surface of the buffer cavity is less than the thickness of the first card shell.

[0009] Further, a buffer cavity movably connected with the kit is further included, a buffer hole is formed in the first card shell, the buffer hole is oppositely arranged with the sample inlet cavity, and the buffer cavity can enter or exit the buffer hole.

[0010] Further, a breakthrough tip located in the sample inlet cavity is further included, the volume of the breakthrough tip decreases from the bottom end to the top end.

[0011] Further, the breakthrough tip does not contact the buffer cavity when the kit is unused, and the breakthrough tip contacts the buffer cavity when the kit is used.

[0012] Further, a part of the surface of the test paper accommodating cavity is recessed in the direction approaching the test paper to form a pressing rib.

[0013] Further, the test paper step is connected with the sample inlet cavity, and the bottom surface of the test paper step forms an obtuse angle with the side surface.

[0014] Further, the first clamping shell extends a positioning column in the direction approaching the test paper step.

[0015] Further, the sample adding hole is covered with a sealing sticker.

[0016] Further, the edge of the sample adding hole extends in the direction approaching the test paper placement direction and contacts the test paper.

[0017] Compared with the prior art, the beneficial effects of the present application include:

[0018] The tester only needs to drop the sample in the sample adding hole and press or squeeze the buffer cavity in the buffer hole, without needing to extract the sample in advance and process the sample, thereby saving the steps of screwing the cap, adding the sample, mixing, etc., reducing the cumbersome process and error probability of diluting the trace sample by the operator outside the card during detection, saving the use of consumables, and being very convenient to operate, so that the user can realize the detection without any training, and the detection result is self-evident and convenient for judgment; the buffer cavity stores a fixed amount of buffer, thereby reducing the influence of too much or too little buffer dropped by the tester on the detection accuracy; the inclined surface of the test paper step can make the buffer and the sample uniformly disperse and move upwards on the test paper and fully react with the detection line and the quality control line, thereby improving the stability and accuracy of the detection reagent; through the cooperation of the test paper accommodating cavity, the pressing rib, the positioning column, and the test paper step, the stability of the test paper installation is improved; after the detection is completed, the test paper, the sample, and the buffer can be completely sealed by the sealing sticker and discarded together, thereby saving the collection and processing process of medical waste and reducing pollution. BRIEF DESCRIPTION OF DRAWINGS

[0019] In order to more clearly illustrate the technical solutions of the embodiments of the present application, the following will briefly introduce the drawings needed to be used in the embodiments. It should be understood that the following drawings only show some embodiments of the present application, and should not be regarded as a limitation on the scope of the present application.

[0020] Figure 1 FIG. 1 is a structural schematic diagram of the detection kit of the present application;

[0021] Figure 2 FIG. 2 is a structural schematic diagram of the first clamping shell of the present application;

[0022] Figure 3 Figure 2 is a schematic diagram of a second cassette structure of the present application;

[0023] Figure 4 Figure 3 is a schematic diagram of a profile structure of a test kit of the present application;

[0024] Figure 5 Figure 4 is a schematic diagram of another embodiment of a test kit structure of the present application;

[0025] Figure 6 Figure 5 is a schematic diagram of a profile structure of another embodiment of a test kit of the present application

[0026] Figure 7 Figure 6 is a schematic diagram of a test paper structure of the present application.

[0027] Reference signs:

[0028] 1 - first cassette; 11 - sample well; 12 - buffer cavity; 13 - test paper containing cavity; 14 - pressing strip rib; 15 - positioning column; 16 - observation window; 17 - buffer hole; 18 - sealing sticker; 19 - auxiliary foot; 20 - outer thread; 2 - second cassette; 21 - test paper step; 22 - sample cavity; 23 - breakthrough tip; 24 - tip; 25 - inner thread; 3 - test paper; 31 - sample pad; 32 - binding pad; 33 - reaction film; 34 - water absorption pad; 35 - bottom card. DETAILED DESCRIPTION

[0029] The technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the drawings in the embodiments of the present application. Obviously, the described embodiments are only part of the embodiments of the present application, rather than all the embodiments of the present application. Based on the embodiments in the present application, all other embodiments obtained by those skilled in the art without creative labor fall within the scope of protection of the present application.

[0030] The terms "horizontal", "two sides", "middle", "bottom", "side", "bottom surface", "bottom end", "top end", "first", "second" and similar expressions used herein are only for the purpose of illustration. The term "and / or" used herein includes any and all combinations of one or more related listed items.

[0031] The test kit of the present application is convenient to use. Please refer to Figures 1-7, including a first card shell 1, a second card shell 2 and a test paper 3, a sample adding hole 11 is formed on the first card shell 1, the sample adding hole 11 can be circular, arc-shaped and other shapes easy to add samples, the sample adding hole 11 can be a hole on a plane, or can extend downward to form a three-dimensional hole, when the edge of the sample adding hole 11 extends close to the placement direction of the test paper 3, the edge contacts the test paper 3 to fix one end of the test paper 3, the extension length of the edge of the sample adding hole 11 can be the same or different; when the reagent box is not used, the sample adding hole 11 is also covered with a sealing sticker 18, which can be a sticker or a movable cover, which can be opened or torn when adding samples, and then sealed after use, saving the collection and processing process of medical waste and reducing environmental pollution; the bottom surface of the second card shell 2 extends downward to form a test paper step 21 with a horizontal bottom surface and an inclined side surface and a sample adding cavity 22 with a depth capable of accommodating a buffer solution, the test paper step 21 is connected with the sample adding cavity 22, the bottom surface and the side surface of the test paper step 21 form an obtuse angle, the inclined side surface can be an equal inclined surface, a convex inclined surface or a concave inclined surface, and the inclined surface can be smooth or provided with convex points or steps; preferably, the extension lengths of the edges of the sample adding hole 11 are different, and cooperate with the horizontal bottom surface and / or the inclined side surface of the test paper step 21 to fix one end of the test paper 3; one of the first card shell 1 and the second card shell 2 is provided with a test paper containing cavity 13, when the first card shell 1 is provided with the test paper containing cavity 13, the position opposite to the test paper containing cavity 13 of the second card shell 2 is a plane, when the second card shell 2 is provided with the test paper containing cavity 13, the position opposite to the test paper containing cavity 13 of the first card shell 1 is a plane, the test paper containing cavity 13 can contain and limit part of the test paper 3 in space, the test paper 3 includes a sample pad 31, a conjugate pad 32, a reaction membrane 33, a water absorption pad 34 and a bottom card 35, specifically, the test paper containing cavity 13 contains and limits the conjugate pad 32, the reaction membrane 33, the water absorption pad 34 and the bottom card 35 part of the test paper 3, the test paper step 21 contains and limits the sample pad 31 and the bottom card 35 part, the sample pad 31 part has a certain angle with the conjugate pad 32, the reaction membrane 33 and the water absorption pad 34, the angle is an obtuse angle, the arrangement of the test paper step 21 can make the sample not rush into the reaction membrane 33 too quickly and too much after being dropped into the sample adding hole 11, avoid the adverse effects of sample flushing and improve the success rate of using the test paper 3.

[0032] When the first and second card shells 1 and 2 are both transparent materials, the kit can not be provided with the observation window 16, and the detection result of the reaction film 33 can be observed through the transparent card shell; or the card shell provided with the test paper accommodating cavity 13 is transparent material, and the card shell not provided with the test paper accommodating cavity 13 is non-transparent material, and the detection result of the reaction film 33 can be observed through the transparent test paper accommodating cavity 13; or only the test paper accommodating cavity 13 is transparent material, and the rest is non-transparent material, and the detection result of the test paper reaction film 33 can be observed through the transparent test paper accommodating cavity 13; or the observation window 16 is provided on the test paper accommodating cavity 13 opposite to the reaction film 33, the observation window 16 leaks part of the test paper 3, and the detection result of the reaction film 33 can be observed conveniently, and when the kit is not used, the observation window 16 is further covered with the sealing sticker 18, and the sealing sticker 18 can be a sticker or a movable cover.

[0033] The kit further comprises a buffer cavity 12 fixedly connected with the first card shell 1, the buffer cavity 12 is located on the first card shell 1 on the same side as the sample adding hole 11, and is arranged opposite to the sample adding cavity 22 of the second card shell 2, the bottom of the buffer cavity 12 is substantially at the same horizontal line as the first card shell 1, the thickness of the bottom of the buffer cavity 12 is relatively thin, preferably, the thickness of the bottom surface of the buffer cavity 12 is less than the thickness of the first card shell 1, when it is necessary to add buffer, the two sides of the buffer cavity 12 can be squeezed by hand or the upper end of the buffer cavity 12 can be pressed by hand, the bottom of the buffer cavity 12 will be broken and opened, the buffer flows into the inside of the sample adding cavity 22 and is chromatographed along the sample pad 31 of the test paper 3; the breakthrough tip 23 can also be arranged at the position opposite to the buffer hole 17 of the second card shell 2, the volume of the breakthrough tip 23 decreases from the bottom end to the top end, that is, the top end position of the breakthrough tip 23 closest to the buffer hole 17 has a small diameter and a small volume, and the top end edge is sharp to form a tip 24, having a “needle” effect; when the two sides of the buffer cavity 12 are squeezed by hand or the upper end of the buffer cavity 12 is pressed by hand, the bottom of the buffer cavity 12 will contact the tip 24 of the breakthrough tip 23, so that the bottom of the buffer cavity 12 is broken, and the number of the breakthrough tip 23 can be one or more, preferably, the number of the breakthrough tip 23 is one and is arranged at the center of the sample adding cavity 22.

[0034] The kit further comprises a buffer cavity 12 movably connected with the first card shell 1, a buffer hole 17 is formed on the first card shell 1, the buffer hole 17 is arranged opposite to the sample cavity 22, the buffer cavity 12 can enter or exit the buffer hole 17, and the second card shell 2 is also provided with breakthrough tips 23 at positions opposite to the buffer hole 17, preferably, the number of the breakthrough tips 23 is four, which are arranged around the center of the sample cavity 22; when the buffer is needed, the buffer cavity 12 enters the buffer hole 17, the bottom surface of the buffer cavity 12 contacts the breakthrough tips 23, then the bottom of the buffer cavity 12 is opened, and the buffer flows into the sample cavity 22; when the kit is not used, the buffer hole 17 can be closed, the buffer hole 17 is covered with a closing sticker 18, the closing sticker 18 can be a sticker or a movable cover, when the kit is used, the closing sticker 18 is torn, and the buffer cavity 12 is clamped to the buffer hole 17, the buffer cavity 12 can close the buffer hole 12, and the close cooperation between the buffer cavity 12 and the buffer hole 17 can be achieved by structures matched with each other, such as protrusions and recesses, external threads and internal threads and the like, preferably, the buffer cavity 12 and the buffer hole 12 are matched by external threads and internal threads, when further screwed in place, the bottom of the buffer cavity 12 is completely opened, during the rotation process, the buffer cavity 12 first contacts the tips 24 of the breakthrough tips 23, then the breakthrough tips 23 pierce the buffer cavity 12 and further enter into the buffer cavity 12, as the buffer cavity 12 rotates, the breakthrough tips 23 completely cut the bottom of the buffer cavity 12.

[0035] Part of the shell surface of the test paper containing cavity 13 is recessed in the direction close to the test paper to form a pressing rib 14, the number of the pressing rib 14 is not limited, preferably, the number of the pressing rib is two, which are arranged at the middle part of the test paper containing cavity 13; at the position opposite to the test paper step 21 of the first card shell 1, the first card shell 1 extends a positioning column 15 in the direction close to the test paper step 21, the number of the positioning column 15 is not limited, preferably, the number is one, the middle part of the positioning column 15 is hollow, when the first card shell 1, the test paper 3 and the second card shell 2 are combined, the positioning column 15 can fix part of the test paper 3, and the stability of the test paper installation is improved; the second card shell 2 can further be provided with an auxiliary foot 19, which assists the stable placement of the kit; the kit can be made by suction forming and cooperating with hot pressing or ultrasonic pressing

[0036] Finally, it should be noted that: the above embodiments are only used to illustrate the technical solutions of the present application, but not to limit them; although the present application has been described in detail with reference to the foregoing embodiments, those skilled in the art should understand that: they can still modify the technical solutions recorded in the foregoing embodiments, or make equivalent replacement for part or all of the technical features; and these modifications or replacements do not make the essence of the corresponding technical solutions deviate from the scope of the technical solutions of the embodiments of the present application.

[0037] Furthermore, to the extent that the terms "comprises", "comprising", "includes", "including" and "has" or any variation thereof are used in the following description and / or claims, such terms are intended to include a non-exclusive inclusion. For example, a process, method, article, or apparatus that comprises a list of elements is not necessarily limited to only those elements but can include other elements not expressly listed or inherent to such process, method, article, or apparatus. Also, where appropriate to context, the above description and / or claims can refer to actions to be taken by a person or apparatus. Such actions are sometimes referred to as being taken by an "operator" or "user" where it is contextualually appropriate. However, such actions, or steps, are taken autonomously and automatically by an apparatus, without intervention of a person.

Claims

1. A convenient test kit, characterized by, The application relates to a reagent box. The first card shell (1) is provided with a sample adding hole (11). The second card shell (2) is provided with a test paper step (21) and a sample adding cavity (22). One of the first card shell (1) and the second card shell (2) is provided with a test paper containing cavity (13), the test paper containing cavity (13) is placed with test paper (3), one end of the test paper (3) is fixed to the test paper step (21), and the other end is fixed to the test paper containing cavity (13).

2. The ready-to-use test kit according to claim 1, characterized in that The reagent box is further provided with a buffer cavity (12) movably connected with the reagent box, a buffer hole (17) is formed in the first card shell (1), the buffer hole (17) is arranged opposite to the sample adding cavity (22), and the buffer cavity (12) can enter or leave the buffer hole (17).

3. The ready-to-use test kit according to claim 1, characterized in that The reagent box is further provided with a breakthrough tip (23) located in the sample adding cavity (22), the volume of the breakthrough tip (23) decreases from the bottom end to the top end.

4. The ready-to-use test kit according to claim 2 or 3, characterized in that When the reagent box is not used, the breakthrough tip (23) does not contact the buffer cavity (12), and when the reagent box is used, the breakthrough tip (23) contacts the buffer cavity (12).

5. The ready-to-use test kit according to claim 4, characterized in that Part of the surface of the test paper containing cavity (13) is recessed to form a pressing rib (14) in the direction close to the test paper (3).

6. The ready-to-use test kit according to claim 1, characterized in that The test paper step (21) is connected with the sample adding cavity (22), and the bottom surface and the side surface of the test paper step (21) form an obtuse angle.

7. The ready-to-use test kit according to claim 1, characterized in that The first card shell (1) is extended in the direction close to the test paper step (21) and is provided with a positioning column (15).

8. The ready-to-use test kit according to claim 1 or 7, characterized in that The sample adding hole (11) is covered with a sealing sticker (18).

9. The ready-to-use test kit according to claim 1, characterized in that The edge of the sample adding hole (11) is extended in the direction close to the test paper (3) and is in contact with the test paper (3).

10. The ready-to-use test kit according to claim 1, characterized in that ​

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