PMT light measuring device

Abstract

The utility model discloses a PMT light measuring device which comprises a base, one side of the top of the base is fixedly arranged on a support, the top of the base is further provided with a light measuring mechanism, the outer edge of the periphery of the top of the base is detachably connected with a light shield, and the light shield wraps the light measuring mechanism and the support. The light measuring mechanism comprises a light path assembly and a motion assembly. The beneficial effects of the utility model are that through the light path assembly and the motion assembly on the pedestal, a light emitting signal generated by the reaction of a sample and a reagent in the reaction cup reaches the semi-transparent and semi-reflective mirror through the first lens, and the light emitted by the laser light source synchronously passes through the semi-transparent and semi-reflective mirror; the two light sources are processed and reflected by the semi-transparent and semi-reflecting mirror and reach the PMT body through the second lens for signal collection, meanwhile, when the PMT body collects signals, the shutter blocking piece is controlled to be opened through the motor, after collection is completed, the shutter blocking piece is closed, the light shielding performance is good, installation is convenient, whole machine layout is convenient, space is saved, and practicability is high.

Description

Technical Field

[0001] This utility model relates to the field of PMT photometry technology, specifically to a PMT photometry device. Background Technology

[0002] Chemiluminescence immunoassay is an immunological detection method based on the principle of chemiluminescence. It utilizes a specific chemical reaction to trigger a fluorescence or chemiluminescence reaction to detect target substances. In actual testing, the sample is mixed with an appropriate immunoassay reagent (such as antibodies or antigens) to induce a specific immunoreaction, forming a stable antigen-antibody complex. A chemiluminescent reagent (such as an enzyme-labeled substrate) is then added and activated. When the chemiluminescent reagent binds to the antigen-antibody complex, it triggers a fluorescence or chemiluminescence reaction, generating a luminescent signal. The intensity of the luminescent signal is detected using a detection instrument, such as a PMT (photomultiplier tube), to determine the presence and concentration of the target substance. Utility Model Content

[0003] The purpose of this invention is to overcome the shortcomings of the above-mentioned background technology and provide a PMT photometric device.

[0004] Includes a base, one side of the top of the base is fixed to a bracket, a light metering mechanism is also installed on the top of the base, and a light shield is detachably connected to the outer edge of the top of the base, the light shield covering the light metering mechanism and the bracket;

[0005] The photometric mechanism includes an optical path component and a motion component. The optical path component is connected to the base and located on one side of the bracket. The motion component is mounted on the bracket. The optical path component and the motion component are arranged on the left and right sides respectively. The bottom of the base has an opening, and a reaction cup is provided inside the opening. The reaction cup is inserted into the interior of the optical path component.

[0006] Furthermore, the motion component includes a driving wheel and a driven wheel disposed on one side of the bracket. The driving wheel and the driven wheel are arranged one above the other. The driving wheel and the driven wheel are located on the side of the bracket facing the optical path component. A synchronous belt is sleeved between the driving wheel and the driven wheel.

[0007] Furthermore, the motion component also includes a motor, which is mounted on one side of the bracket, with the motor output end connected to the driving wheel and the driven wheel rotatably mounted on the bracket.

[0008] Furthermore, a shutter stop is fixedly provided on one side of the driven wheel, and the center point of the shutter stop is connected to the driven wheel.

[0009] Furthermore, multiple circular holes are provided on one side of the shutter stop.

[0010] Furthermore, a PMT body is mounted on one side of the bracket, the PMT body is located below the driven wheel, the output end of the PMT body is correspondingly arranged with the optical path assembly, and the shutter stop is movable between the optical path assembly and the PMT body.

[0011] Furthermore, the optical path assembly includes a fixing seat connected to the base, the interior of the fixing seat is a cavity, and a first through hole and a second through hole are respectively opened on the bottom and one side of the fixing seat. The first through hole and the second through hole communicate with the cavity. The reaction cup is inserted into the first through hole, and the output end of the PMT body corresponds to the second through hole.

[0012] Furthermore, a first lens and a second lens are respectively disposed inside the first through hole and the second through hole.

[0013] Furthermore, a semi-transparent mirror is inclinedly arranged inside the cavity, and a laser light source is installed on the top of the fixing base. The laser light source corresponds to one side of the semi-transparent mirror, and the first lens and the second lens both correspond to the other side of the semi-transparent mirror.

[0014] Furthermore, an optical coupler is installed on one side of the bracket, and an optical coupler baffle is installed on the inner ring of the synchronous belt. The optical coupler baffle and the optical coupler are movably connected.

[0015] Compared with the prior art, the advantages of this utility model are as follows: Through the optical path component and motion component on the base, the light emission signal generated by the reaction of the sample and reagent in the reaction cup reaches the semi-transparent mirror through the first lens, and the laser light emitted by the laser source synchronously passes through the semi-transparent mirror. The two light sources are reflected by the semi-transparent mirror and reach the PMT body through the second lens for signal acquisition. At the same time, when the PMT body acquires the signal, the shutter baffle is opened by the motor control and closed after the acquisition is completed. This achieves good light protection, is easy to install, facilitates the overall layout of the machine, saves space, and is highly practical. Attached Figure Description

[0016] Figure 1 This is a schematic diagram of the overall three-dimensional structure of this utility model.

[0017] Figure 2 This is a three-dimensional structural diagram of the photometric mechanism in this utility model.

[0018] Figure 3 This is a schematic diagram of the optical path component structure in this utility model.

[0019] In the picture:

[0020] 1. Metering mechanism;

[0021] 2. Reaction cup;

[0022] 3. Sunshade;

[0023] 4. Base;

[0024] 5. Bracket;

[0025] 6. Electric motor;

[0026] 7. Drive wheel;

[0027] 8. Synchronous belt;

[0028] 9. Driven wheel;

[0029] 10. Shutter stop;

[0030] 11. Optical coupler;

[0031] 12. Optical coupler baffle;

[0032] 13. Fixture;

[0033] 14. Laser light source;

[0034] 15. Semi-transparent and semi-reflective mirror;

[0035] 16. First lens;

[0036] 17. Second lens;

[0037] 18. PMT body. Detailed Implementation

[0038] Referring now to specific embodiments of the present invention, examples of which are illustrated in the accompanying drawings. Although the present invention will be described in conjunction with specific embodiments, it will be understood that it is not intended to limit the present invention to the described embodiments. Rather, it is intended to cover variations, modifications, and equivalents included within the spirit and scope of the present invention as defined by the appended claims. It should be noted that the method steps described herein can be implemented by any functional block or functional arrangement, and any functional block or functional arrangement can be implemented as a physical entity or a logical entity, or a combination of both.

[0039] To enable those skilled in the art to better understand this utility model, the present utility model will be further described in detail below with reference to the accompanying drawings and specific embodiments.

[0040] Note: The examples described below are merely specific examples and are not intended to limit the embodiments of this utility model to the specific steps, values, conditions, data, order, etc. Those skilled in the art can utilize the concept of this utility model to construct more embodiments not mentioned herein by reading this specification.

[0041] Chemiluminescence immunoassay is an immunological detection method based on the principle of chemiluminescence. It utilizes a specific chemical reaction to trigger a fluorescence or chemiluminescence reaction to detect target substances. In actual testing, the sample is mixed with an appropriate immunoassay reagent (such as antibodies or antigens) to induce a specific immunoreaction, forming a stable antigen-antibody complex. A chemiluminescent reagent (such as an enzyme-labeled substrate) is then added and activated. When the chemiluminescent reagent binds to the antigen-antibody complex, it triggers a fluorescence or chemiluminescence reaction, generating a luminescent signal. The intensity of the luminescent signal is detected using a detection instrument, such as a PMT (photomultiplier tube), to determine the presence and concentration of the target substance.

[0042] To address the aforementioned problems with PMT (Photometric Measurement) devices, this invention proposes a PMT measurement device.

[0043] Please see Figure 1 The system includes a base 4, with one side of the top of the base 4 fixed to a bracket 5. A photometer 1 is also installed on the top of the base 4. A light shield 3 is detachably connected to the outer edge of the top of the base 4, and the light shield 3 covers the photometer 1 and the bracket 5. The photometer 1 includes an optical path component and a motion component. The optical path component is connected to the base 4 and located on one side of the bracket 5. The motion component is installed on the bracket 5. The optical path component and the motion component are arranged on the left and right sides respectively. An opening is provided at the bottom of the base 4, and a reaction cup 2 is provided inside the opening. The reaction cup 2 is inserted into the interior of the optical path component.

[0044] like Figure 1 As shown, the base 4 has a square structure, while the light shield 3 has a square cylindrical structure. The light shield 3 is connected to the base 4 by bolts. The light metering mechanism 1 is installed on the base 4, and the light shield 3 covers the light metering mechanism 1. A bracket 5 is integrally formed on the base 4. The light metering mechanism 1 includes an optical path component and a motion component. The optical path component is installed on the base 4, and the motion component is installed on the bracket 5. The two are arranged on the left and right sides. An opening is made at the bottom of the base 4 at the position of the optical path component, so that the reaction cup 2 can be inserted into the opening and the top can be inserted into the optical path component. This achieves good light protection, convenient installation, convenient overall layout, space saving and strong practicality.

[0045] Please see Figure 1 and Figure 2The motion assembly includes a drive wheel 7 and a driven wheel 9 located on one side of the bracket 5. The drive wheel 7 and the driven wheel 9 are arranged one above the other and are located on the side of the bracket 5 facing the optical path assembly. A synchronous belt 8 is sleeved between the drive wheel 7 and the driven wheel 9. The motion assembly also includes a motor 6, which is mounted on one side of the bracket 5. The output end of the motor 6 is connected to the drive wheel 7. The driven wheel 9 is rotatably mounted on the bracket 5. A shutter stop 10 is fixed on one side of the driven wheel 9. The center point of the shutter stop 10 is connected to the driven wheel 9. Multiple round holes are opened on one side of the shutter stop 10.

[0046] like Figure 1 and Figure 2 As shown, the motion assembly mainly consists of a drive wheel 7, a driven wheel 9, a synchronous belt 8, and a motor 6. The drive wheel 7 and the driven wheel 9 are mounted on one side of the bracket 5, and the synchronous belt 8 is fitted between the drive wheel 7 and the driven wheel 9. The motor 6 is mounted on the other side of the bracket 5. The drive wheel 7 is connected to the output end of the motor 6, and the driven wheel 9 is rotatably connected to one side of the bracket 5. During the rotation of the drive wheel 7 by the motor 6, the driven wheel 9 is also rotated. A shutter stop 10 is connected to one side of the driven wheel 9. The shutter stop 10 is located on one side of the optical path assembly. During the rotation of the shutter stop 10, the circular hole on one side of the shutter stop 10 moves continuously, achieving the effect of rapid opening and closing.

[0047] Please continue reading. Figure 1 and Figure 2 A PMT body 18 is mounted on one side of the bracket 5. The PMT body 18 is located below the driven wheel 9. The output end of the PMT body 18 is set in correspondence with the optical path assembly. The shutter stop 10 moves between the optical path assembly and the PMT body 18.

[0048] like Figure 1 and Figure 2 As shown, referring to the above embodiment, the shutter stop 10 is located on one side of the PMT body 18, and the circular hole of the shutter stop 10 is adapted to the PMT body 18. When the circular hole of the shutter stop 10 moves to the corresponding position of the PMT body 18, the PMT body 18 is opened; otherwise, the circular hole rotates and moves open, and the PMT body 18 is closed.

[0049] Please see Figure 1 and Figure 3The optical path assembly includes a fixed base 13 connected to the base 4. The interior of the fixed base 13 is a cavity. The bottom and one side of the fixed base 13 are respectively provided with a first through hole and a second through hole, which communicate with the cavity. The reaction cup 2 is inserted into the first through hole. The output end of the PMT body 18 corresponds to the second through hole. The first through hole and the second through hole are respectively provided with a first lens 16 and a second lens 17. A semi-transparent mirror 15 is inclinedly arranged inside the cavity. A laser source 14 is installed on the top of the fixed base 13. The laser source 14 corresponds to one side of the semi-transparent mirror 15. The first lens 16 and the second lens 17 both correspond to the other side of the semi-transparent mirror 15.

[0050] like Figure 1 and Figure 2 As shown, the optical path assembly mainly consists of a laser light source 14, a first lens 16, a second lens 17, a semi-transparent mirror 15, and a mounting base 13. First, the sample and reagent in the reaction cup 2 react to generate a light emission signal, which passes through the first lens 16 to the semi-transparent mirror 15. At the same time, the laser light source 14 emits light that passes synchronously through the semi-transparent mirror 15. The two light sources are processed and reflected by the semi-transparent mirror 15 and pass through the second lens 17 to the PMT body 18 for signal acquisition. (When the PMT body 18 acquires the signal, the shutter stop 10 is opened by the motor 6 and closed after the acquisition is completed.)

[0051] Please see Figure 1 and Figure 2 An optical coupler 11 is installed on one side of the bracket 5, and an optical coupler baffle 12 is installed on the inner ring of the synchronous belt 8. The optical coupler baffle 12 and the optical coupler 11 are movably connected.

[0052] like Figure 1 and Figure 2 As shown, it can prevent the shutter stop 10 from rotating to an inaccurate position, that is, when the optical coupler stop 12 on the synchronous belt 8 moves to the optical coupler body 11, it transmits a signal and shuts off the motor 6.

[0053] When using this invention, the light emitted by the reaction of the sample and reagent in the reaction cup 2 is transmitted through the first lens 16 to the semi-transparent mirror 15. At the same time, the light emitted by the laser light source 14 is transmitted through the semi-transparent mirror 15. The two light sources are processed and reflected by the semi-transparent mirror 15 and transmitted through the second lens 17 to the PMT body 18 for signal acquisition. When the PMT body 18 acquires the signal, the shutter baffle 10 is opened by the motor 6 and closed after the acquisition is completed.

[0054] In the description of this utility model, it should be noted that the terms "upper," "lower," etc., indicating the orientation or positional relationship are based on the orientation or positional relationship shown in the accompanying drawings, and are only for the convenience of describing this utility model and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of this utility model. Unless otherwise expressly specified and limited, the terms "installed," "connected," and "linked" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; they can refer to the internal connection of two components. For those skilled in the art, the specific meaning of the above terms in this utility model can be understood according to the specific circumstances.

[0055] It should be noted that in this invention, relational terms such as "first" and "second" are used merely to distinguish one entity or operation from another, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Furthermore, the terms "comprising," "including," or any other variations thereof are intended to cover non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements includes not only those elements but also other elements not expressly listed, or elements inherent to such a process, method, article, or apparatus. Without further limitations, an element defined by the phrase "comprising one..." does not exclude the presence of other identical elements in the process, method, article, or apparatus that includes said element.

[0056] The above description is merely a specific embodiment of the present invention, enabling those skilled in the art to understand or implement the present invention. Various modifications to these embodiments will be readily apparent to those skilled in the art, and the general principles defined herein may be implemented in other embodiments without departing from the spirit or scope of the present invention. Therefore, the present invention is not to be limited to the embodiments shown herein, but is to be accorded the widest scope consistent with the principles and novel features of the present invention.

Claims

1. A PMT photometric device, characterized by, It includes the base (4), the top side of the base (4) is fixed to the support (5), the top of the base (4) is also provided with light measuring mechanism (1), the top of the base (4) is detachably connected with the light shield (3) around the outer edge, the light shield (3) wraps the light measuring mechanism (1) and the support (5); The light measuring mechanism (1) includes a light path assembly and a motion assembly, the light path assembly is connected with the base (4) and located on one side of the support (5), the motion assembly is installed on the support (5), the light path assembly and the motion assembly are distributed on the left and right sides, the bottom of the base (4) is provided with an opening, the inside of the opening is provided with a reaction cup (2), and the reaction cup (2) is inserted into the inside of the light path assembly.

2. The PMT photometric device of claim 1, wherein, The motion assembly includes a driving wheel (7) and a driven wheel (9) arranged on one side of the support (5), the driving wheel (7) and the driven wheel (9) are distributed on the upper and lower sides, the driving wheel (7) and the driven wheel (9) are located on the side of the support (5) facing the light path assembly, and the driving wheel (7) and the driven wheel (9) are sleeved with a synchronous belt (8).

3. A PMT photometric device as claimed in claim 2, characterized in that The motion assembly further includes a motor (6) installed on one side of the support (5), the output end of the motor (6) is connected with the driving wheel (7), and the driven wheel (9) is rotatably arranged on the support (5).

4. The PMT photometric device of claim 2, wherein, One side of the driven wheel (9) is fixedly provided with a shutter baffle (10), and the center point of the shutter baffle (10) is connected with the driven wheel (9).

5. A PMT photometric device as claimed in claim 4, characterized in that A plurality of round holes are formed in one side of the shutter baffle (10).

6. A PMT photometric device as claimed in claim 4, characterized in that A PMT body (18) is installed on one side of the support (5), the PMT body (18) is located below the driven wheel (9), the output end of the PMT body (18) is correspondingly arranged with the light path assembly, and the shutter baffle (10) is movably arranged between the light path assembly and the PMT body (18).

7. A PMT photometric device as claimed in claim 6, characterized in that The light path assembly includes a fixing seat (13) connected with the base (4), the inside of the fixing seat (13) is a cavity, the bottom and one side of the fixing seat (13) are respectively provided with a first through hole and a second through hole, the first through hole and the second through hole are communicated with the cavity, the reaction cup (2) is inserted into the first through hole, and the output end of the PMT body (18) corresponds to the second through hole.

8. A PMT photometric device as claimed in claim 7, characterized in that The inside of the first through hole and the second through hole is respectively provided with a first lens (16) and a second lens (17).

9. A PMT photometric device as claimed in claim 8, characterized in that The inside of the cavity is obliquely provided with a half-transmission half-reflection mirror (15), the top of the fixing seat (13) is provided with a laser light source (14), the laser light source (14) corresponds to one side of the half-transmission half-reflection mirror (15), and the first lens (16) and the second lens (17) correspond to the other side of the half-transmission half-reflection mirror (15).

10. The PMT photometric device of claim 2, wherein, One side of the support (5) is provided with a light coupling body (11), the inner ring of the synchronous belt (8) is provided with a light coupling baffle (12), and the light coupling baffle (12) and the light coupling body (11) are movably connected.

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