Biopharmaceutical separating, purifying and filtering device

Abstract

The utility model relates to the technical field of filtration, and discloses a biopharmaceutical separation, purification and filtration device which comprises a cabin body, a window is formed in the front side of the cabin body, a water outlet is formed in the bottom of the cabin body, a rolling module is arranged in the cabin body, a roller is rotationally installed on the rolling module, and a plurality of water permeable holes are formed in the inner wall of the roller in a penetrating mode in the circumferential direction. One end of the roller is sealed, the other end of the roller is provided with a sealing cover, a net sleeve is coaxially arranged in the roller, two ends of the net sleeve are opened, one end of the net sleeve close to the sealing end of the roller is fixedly connected to the positioning disc, and the opening edge of the other end of the net sleeve is annular and fixedly connected with the inner wall of the roller. According to the utility model, the net sleeve is arranged in the roller, and the roller can be turned over, so that materials cannot be directly adhered to the inner wall of the roller due to the obstruction of the net bag in the rotating process of the roller, and all residual materials can be taken out at one time when the net bag is directly taken out from the roller after the filtering is completed; therefore, the filtering operation efficiency is greatly improved.

Description

Technical Field

[0001] This utility model relates to the field of filtration technology, and more specifically, to a biopharmaceutical separation and purification filtration device. Background Technology

[0002] Biopharmaceuticals refer to products manufactured using the research findings of microbiology, biology, medicine, and biochemistry, utilizing the principles and methods of microbiology, chemistry, biochemistry, biotechnology, and pharmacy to prevent, treat, and diagnose diseases from organisms, biological tissues, cells, organs, and body fluids. In the biopharmaceutical process, filtration is necessary to separate and purify certain materials. One existing filtration method is centrifugal filtration, which places the material to be filtered into a drum, and the centrifugal force generated by the rotating drum forces the liquid out of the drum, achieving rapid and efficient filtration. However, in this filtration method, the centrifugal force causes residues to adhere firmly to the inner wall of the drum, making subsequent cleaning very inconvenient due to the numerous perforations on the inner wall of the drum. Summary of the Invention

[0003] In order to overcome the shortcomings of the prior art, this utility model provides a biopharmaceutical separation, purification and filtration device to solve the problems mentioned in the background art.

[0004] To achieve the above objectives, this utility model provides the following technical solution: a biopharmaceutical separation, purification, and filtration device, comprising a chamber, a window on the front side of the chamber, a water outlet at the bottom of the chamber, a rotating module inside the chamber, a roller rotatably mounted on the rotating module, a plurality of water-permeable holes circumferentially perforated on the inner wall of the roller, one end of the roller being sealed, and a sealing cap being installed at the other end of the roller, a mesh sleeve being coaxially placed inside the roller, the mesh sleeve having openings at both ends, the end of the mesh sleeve near the sealed end of the roller being fixedly connected to a positioning plate, and the edge of the opening at the other end of the mesh sleeve being annularly fixedly connected to the inner wall of the roller.

[0005] In a preferred embodiment of this invention, the rolling module includes a positioning frame, a main shaft, and a drive motor. The main shaft is rotatably mounted on the cabin. One end of the main shaft extends into the cabin and is fixedly mounted on the positioning frame. The positioning frame is U-shaped, and a roller is disposed within the positioning frame. Each side of the roller is rotatably connected to the positioning frame via a rotating shaft, with the two rotating shafts coaxially distributed. The other end of the main shaft extends out of the cabin and is connected to the drive motor.

[0006] As a preferred technical solution of this utility model, a limiting plate is coaxially fixedly installed at the end of any one of the rotating shafts. A socket is provided on the circumferential side of the limiting plate, and a screw is inserted into the socket. A connecting plate is threaded on the screw, and the connecting plate is fixedly connected to the positioning frame.

[0007] As a preferred embodiment of this utility model, the positioning disk is made of ferromagnetic material, and several magnets are embedded in the sealed end of the roller, and the magnets attract each other to the positioning disk.

[0008] As a preferred embodiment of this utility model, a push rod is threaded through the sealing end of the roller.

[0009] As a preferred embodiment of this utility model, the roller is made of stainless steel.

[0010] Compared with the prior art, the beneficial effects of this utility model are as follows:

[0011] This invention features a mesh sleeve inside the drum, and the drum can be rotated. During the drum's rotation, the mesh sleeve prevents the material from directly sticking to the inner wall of the drum. After filtration, when the drum is rotated and the mesh sleeve is removed directly from the drum, all residues can be removed at once, thus greatly improving the efficiency of the filtration process. Attached Figure Description

[0012] Figure 1 This is a schematic diagram of the structure of a biopharmaceutical separation, purification, and filtration device according to the present invention. Figure 1 ;

[0013] Figure 2 This is a schematic diagram of the structure of a biopharmaceutical separation, purification, and filtration device according to the present invention. Figure 2 ;

[0014] Figure 3 This is a schematic diagram of the structure of a biopharmaceutical separation, purification, and filtration device according to the present invention. Figure 3 ;

[0015] Figure 4 This is a schematic diagram of the mesh sleeve in a biopharmaceutical separation and purification filtration device according to this utility model. Figure 1 ;

[0016] Figure 5 This is a schematic diagram of the mesh sleeve in a biopharmaceutical separation and purification filtration device according to this utility model. Figure 2 .

[0017] Figure 6 This is a schematic diagram of the mesh sleeve in a biopharmaceutical separation and purification filtration device according to this utility model. Figure 3 .

[0018] In the diagram: 1. Cabin; 2. Main shaft; 3. Positioning frame; 4. Rotary shaft; 5. Roller; 6. Sealing cover; 7. Limiting plate; 8. Screw; 10. Drive motor; 11. Net sleeve; 12. Positioning plate; 13. Magnet; 14. Top rod. Detailed Implementation

[0019] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0020] like Figures 1 to 6 As shown, this utility model provides a biopharmaceutical separation, purification, and filtration device, including a chamber 1. A window is provided on the front side of the chamber 1, and a water outlet is provided at the bottom of the chamber 1. A rotating module is installed inside the chamber 1, and a roller 5 is rotatably mounted on the rotating module. Several permeable holes are circumferentially perforated on the inner wall of the roller 5. One end of the roller 5 is sealed, and a sealing cap 6 is installed at the other end. A mesh sleeve 11 is coaxially placed inside the roller 5, with openings at both ends. The end of the mesh sleeve 11 closest to the sealed end of the roller 5 is fixedly connected to a positioning plate 12, and the edge of the opening at the other end of the mesh sleeve 11 is annularly fixedly connected to the inner wall of the roller 5. The roller 5 is made of stainless steel.

[0021] The rolling module includes a positioning frame 3, a main shaft 2, and a drive motor 10. The main shaft 2 is rotatably mounted on the cabin 1. One end of the main shaft 2 extends into the cabin 1 and is fixedly mounted on the positioning frame 3. The positioning frame 3 is U-shaped, and a roller 5 is set in the positioning frame 3. The two sides of the roller 5 are rotatably connected to the positioning frame 3 through a rotating shaft 4. The two rotating shafts 4 are coaxially distributed. The other end of the main shaft 2 extends out of the cabin 1 and is connected to the drive motor 10 for transmission.

[0022] A limiting plate 7 is coaxially fixed to the end of any one of the rotating shafts 4. A circumferential insertion hole is provided on the limiting plate 7, into which a screw 8 is inserted. A connecting plate is threaded onto the screw 8, and the connecting plate is fixedly connected to the positioning frame 3. During normal use, when the screw 8 is inserted into the insertion hole, the main shaft 2 is locked, and the roller 5 is in a horizontal position. When the screw 8 is unscrewed out of the insertion hole, the main shaft 2 is not locked, and the roller 5 can be rotated.

[0023] The positioning disk 12 is made of ferromagnetic material, and several magnets 13 are embedded in the sealed end of the roller 5. The magnets 13 and the positioning disk 12 attract each other.

[0024] A push rod 14 is threaded through the sealed end of the drum 5. Several magnets 13 are arranged in a ring around the central axis of the positioning disk 12. The positioning rod is placed between the ring-arranged magnets 13. During the rotation of the drum 5, the magnetic force of the magnets 13 is used to attract the positioning disk 12 to the sealed end of the drum 5, which can prevent the positioning disk 12 from shifting during rotation. In order to facilitate the ejection of the positioning disk 12 when emptying the material in the drum 5, the push rod 14 is provided. By rotating the push rod 14, the push rod 14 can push the positioning disk 12 downward a certain distance, thereby increasing the distance between the magnets and the positioning disk 12, resulting in a weakening of the magnetic force between them. Under the action of gravity, the positioning disk 12 is detached from the drum 5 downward.

[0025] In use, the material to be filtered is placed into the mesh sleeve 11 inside the drum 5, and then the sealing cover 6 is closed. At this time, the drum 5 is in the state shown in the attached figure. Figure 1 As shown, the drive motor 10 is then started. The drive motor 10 drives the main shaft 2 to rotate the positioning frame 3. The positioning frame 3 drives the entire drum 5 to rotate synchronously. The centrifugal force generated by the rotation causes the liquid in the material inside the drum 5 to be thrown out of the drum 5. After being intercepted by the inner wall of the chamber 1, it flows out through the bottom outlet. At this time, because the drum 5 is equipped with a mesh sleeve 11, the material will not directly adhere to the inner wall of the drum 5 during rotation, but will be blocked by the mesh sleeve. After filtration is completed, as shown in the attached image... Figure 3 As shown, flip roller 5 so that its open end faces downwards, then remove the sealing cover 6 from roller 5. At this point, as shown in the attached diagram... Figure 5-6 As shown, the positioning disc 12 on the inner mesh sleeve 11 of the roller 5 moves downward under the action of gravity, thereby causing the mesh sleeve 11 to flip out of the roller 5. During the flipping process, the material in the mesh sleeve 11 is also carried out of the roller 5 at the same time.

[0026] This allows for rapid material unloading, significantly improving operational efficiency. It should be noted that in this document, relational terms such as "first" and "second" are used merely to distinguish one entity or operation from another, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Furthermore, the terms "comprising," "including," or any other variations thereof are intended to cover non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements includes not only those elements but also other elements not expressly listed, or elements inherent to such process, method, article, or apparatus.

[0027] Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the present invention, the scope of which is defined by the appended claims and their equivalents.

Claims

1. A biopharmaceutical separation purification filtration device comprising a cabin (1), characterized in that: The cabin body (1) is provided with a window on the front side, and is provided with a water outlet on the bottom, and is provided with a rolling module inside, the rolling module is provided with a roller (5) rotatably installed on it, a plurality of water-permeable holes are formed in the inner wall of the roller (5) in the circumferential direction, one end of the roller (5) is sealed, and the other end of the roller (5) is provided with a sealing cover (6), the roller (5) is coaxially placed with a mesh sleeve (11) inside, the mesh sleeve (11) is provided with openings at both ends, and one end of the mesh sleeve (11) close to the sealing end of the roller (5) is fixedly connected to a positioning disc (12), and the other end of the mesh sleeve (11) is annularly fixedly connected to the inner wall of the roller (5).

2. A biopharmaceutical separation and purification filtration device according to claim 1, wherein: The rolling module comprises a positioning frame (3), a main shaft (2) and a driving motor (10), the main shaft (2) is rotatably installed on the cabin body (1), one end of the main shaft (2) extends into the cabin body (1) and is fixedly installed with the positioning frame (3), the positioning frame (3) is in a U shape, the roller (5) is arranged in the positioning frame (3), the roller (5) is rotatably connected to the positioning frame (3) through a rotating shaft (4) on each side, the two rotating shafts (4) are coaxially distributed, and the other end of the main shaft (2) extends out of the cabin body (1) and is drivingly connected with the driving motor (10).

3. A biopharmaceutical separation and purification filtration device according to claim 2, wherein: One end of the rotating shaft (4) is coaxially fixedly installed with a limiting disc (7), the limiting disc (7) is provided with an insertion hole in the circumferential direction, a screw rod (8) is inserted in the insertion hole, a connecting plate is threadedly installed on the screw rod (8), and the connecting plate is fixedly connected with the positioning frame (3).

4. The biopharmaceutical separation and purification filtration device of claim 1, wherein: The positioning disc (12) is made of ferromagnetic material, a plurality of magnets (13) are embedded and installed on the sealing end of the roller (5), and the magnets (13) and the positioning disc (12) are attracted to each other.

5. A biopharmaceutical separation and purification filtration device according to claim 4, wherein: A jack (14) is threadedly installed on the sealing end of the roller (5).

6. The biopharmaceutical separation and purification filtration device of claim 1, wherein: The roller (5) is made of stainless steel.

Images