Detection platform for quantum dot fluorescence immunoassay analyzer

Abstract

The utility model relates to the technical field of quantum dot fluorescence immunoassay analyzers, in particular to a detection platform for a quantum dot fluorescence immunoassay analyzer. The detection platform for the quantum dot fluorescence immunoassay analyzer comprises a detection table and an immunoassay analyzer body mounted on one side of the detection table, and the immunoassay analyzer body is provided with a detection window for placing a sample for detection; the control box is mounted on the other side of the detection table; the stand column is fixedly installed on the detection table and located on one side of the detection window, a sleeve is rotationally installed on the stand column, a hollow annular disc is fixedly installed at the top end of the sleeve, a plurality of through grooves are evenly formed in the annular disc, supporting shafts are rotationally installed in the through grooves through damping sleeve shafts, and bearing blocks are fixedly installed on the supporting shafts; the upper end and the lower end of the bearing block are each provided with a containing assembly used for containing a sample. The detection platform for the quantum dot fluorescence immunoassay analyzer provided by the utility model has the advantage of high efficiency and rapidness in detection.

Description

Technical Field

[0001] This utility model relates to the field of quantum dot fluorescence immunoassay analyzer technology, and in particular to a detection platform for a quantum dot fluorescence immunoassay analyzer. Background Technology

[0002] The detection principle of the quantum dot fluorescence immunoassay analyzer is as follows: The sample diffuses upwards at the sample application end (whole blood filtration membrane) due to capillary action. Upon passing through the quantum dot-labeled pad (containing antibody-labeled quantum dots), the analyte (antigen) in the sample binds to the antibody-quantum dot conjugate, forming a quantum dot-labeled antibody-antigen complex. This complex continues to diffuse onto the nitrocellulose membrane, where it is intercepted by the T-line (detection line) coated with antibody 2, capturing the complex and forming an immune complex of quantum dot-labeled antibody-antigen-coated antibody. The uninterrupted quantum dot conjugate continues to ascend and binds to the antibody coated on the C-line (control line), indicating the completion of the reaction. Using appropriate instruments, the reaction area of ​​the test card is tested, and a fluorescence detection signal is obtained by exciting the quantum dots. The content of the analyte in the sample is determined based on a standard curve.

[0003] Currently, in actual testing processes, samples are loaded and unloaded individually, which is inefficient and cannot achieve large-scale automated testing.

[0004] Therefore, it is necessary to provide a new detection platform for quantum dot fluorescence immunoassay analyzers to solve the above-mentioned technical problems. Utility Model Content

[0005] To solve the above-mentioned technical problems, this utility model provides a detection platform for a quantum dot fluorescence immunoassay analyzer.

[0006] The detection platform for the quantum dot fluorescence immunoassay analyzer provided by this utility model includes: a detection stage, and an immunoassay analyzer body installed on one side of the detection stage, wherein the immunoassay analyzer body is provided with a detection window for placing samples for detection.

[0007] The control box is installed on the other side of the testing station;

[0008] A column is fixedly installed on the detection platform and located on one side of the detection window. A sleeve is rotatably installed on the column, and a hollow annular disk is fixedly installed at the top of the sleeve. Several through slots are evenly opened on the annular disk, and a support shaft is rotatably installed in each of the through slots through a damping sleeve shaft. A bearing block is fixedly installed on the support shaft. Placement components for holding samples are installed at both the upper and lower ends of the bearing block. A drive component for driving the support shaft to rotate at a fixed point is installed on the outer wall of the top of the column. A pusher component for pushing the placement component located directly in front of the detection window into the detection window is installed at the top of the column.

[0009] Preferably, a driven gear is fixedly sleeved on the outer wall of the bottom end of the sleeve, a servo motor is fixedly installed on one side of the bottom end of the sleeve on the detection platform, a driving gear is fixedly sleeved on the output shaft of the servo motor, the driving gear meshes with the driven gear, and the servo motor is electrically connected to the control box.

[0010] Preferably, the placement component includes a drawer cage, with sliders symmetrically installed at the rear end of the drawer cage. A groove for sliding engagement of the slider is provided on the support block, and a baffle is fixedly installed at the end of the groove. A return spring is fixedly installed on the baffle, with one end extending into the groove and fixedly connected to the slider. The drawer cage is adapted to the detection window.

[0011] Preferably, the driving component includes a lower abutment plate and a transmission gear. The lower abutment plate is fixedly installed on the outer side wall of the top of the column, and an incomplete tooth is fixedly installed on the side of the lower abutment plate that is offset from the detection window. The transmission gear is provided in several parts, and the several transmission gears are sleeved on several support shafts. When the several transmission gears rotate to the side that is offset from the detection window, they mesh with the incomplete tooth.

[0012] Preferably, the number of teeth in the incomplete tooth is the same as the number of teeth in the transmission gear.

[0013] Preferably, a collection bucket is provided below the incomplete tooth, and the collection bucket is placed on the testing table.

[0014] Preferably, the pushing component includes an electric telescopic rod, which is fixedly installed on the top of the column, with the telescopic end of the electric telescopic rod facing the side of the detection window and flush with the placement component above.

[0015] Compared with related technologies, the detection platform for the quantum dot fluorescence immunoassay analyzer provided by this utility model has the following advantages:

[0016] 1. This utility model provides a detection platform for a quantum dot fluorescence immunoassay analyzer. By placing the support block in the through groove using a support shaft, and setting placement components at both ends of the support block, the platform can be automatically flipped and unloaded after detection using a driving component, which facilitates rapid detection.

[0017] 2. The placement component utilizes the cooperation of a drawer cage, slider, baffle, and return spring. Under the push of the pusher, it can be quickly pushed in front of the detection window and automatically reset after detection, making detection convenient to use. Attached Figure Description

[0018] Figure 1 A schematic diagram of a preferred embodiment of the detection platform for the quantum dot fluorescence immunoassay analyzer provided by this utility model;

[0019] Figure 2 A schematic diagram of a column with a sleeve installed on it, provided by this utility model;

[0020] Figure 3 This is a structural schematic diagram of the support block and placement component provided by this utility model;

[0021] Figure 4 An exploded structural diagram of the support block and placement components provided by this utility model.

[0022] The diagram is labeled as follows: 1. Detection stage; 11. Servo motor; 111. Drive gear; 12. Collection bucket; 2. Immunoassay analyzer body; 201. Detection window; 3. Column; 31. Sleeve; 311. Driven gear; 4. Circular disc; 401. Through groove; 5. Support shaft; 51. Bearing block; 501. Groove; 6. Placement assembly; 61. Drawer cage; 62. Slider; 63. Baffle; 64. Return spring; 7. Drive component; 71. Lower abutment plate; 72. Incomplete gear; 73. Transmission gear; 8. Pushing component; 81. Electric telescopic rod; 9. Control box. Detailed Implementation

[0023] To make the objectives, technical solutions, and advantages of this utility model clearer, the present utility model will be further described in detail below with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are merely illustrative of the present utility model and are not intended to limit the present utility model.

[0024] The specific implementation of this utility model will be described in detail below with reference to specific embodiments.

[0025] Please see Figures 1 to 4 This utility model provides a detection platform for a quantum dot fluorescence immunoassay analyzer, the detection platform comprising:

[0026] The test station 1 and the immunoassay analyzer body 2 installed on one side of the test station 1, wherein the immunoassay analyzer body 2 is provided with a test window 201 for placing samples for testing;

[0027] Control box 9 is installed on the other side of the testing station 1;

[0028] A column 3 is fixedly installed on the detection table 1 and located on one side of the detection window 201. A sleeve 31 is rotatably installed on the column 3. A hollow annular disk 4 is fixedly installed at the top of the sleeve 31. Several through slots 401 are evenly opened on the annular disk 4. A support shaft 5 is rotatably installed in each of the several through slots 401 through a damping sleeve shaft. A bearing block 51 is fixedly installed on the support shaft 5. Placement components 6 for holding samples are installed at both the upper and lower ends of the bearing block 51. A drive component 7 for driving the support shaft 5 to rotate at a fixed point is installed on the outer wall of the top of the column 3. A pusher 8 for pushing the placement component 6 located directly in front of the detection window 201 into the detection window 201 is installed at the top of the column 3.

[0029] The placement component 6 includes a drawer cage 61, with sliders 62 symmetrically mounted at the rear end of the drawer cage 61. The support block 51 has a groove 501 for sliding engagement with the sliders 62. A baffle 63 is fixedly mounted at the end of the groove 501. A return spring 64 is fixedly mounted on the baffle 63, with one end extending into the groove 501 and fixedly connected to the slider 62. The drawer cage 61 is adapted to the detection window 201.

[0030] The pusher 8 includes an electric telescopic rod 81, which is fixedly installed on the top of the column 3, with the telescopic end of the electric telescopic rod 81 facing the side of the detection window 201 and flush with the placement component 6 above it.

[0031] It should be noted that during use, the sample to be tested is placed in the drawer cage 61. Then, as the annular disk 4 rotates, when it is aligned with the detection window 201, the electric telescopic rod 81 is controlled to push the drawer cage 61 above, pushing it into the detection window 201 for testing. After testing, the electric telescopic rod 81 retracts and resets. Under the action of the reset spring 64, the drawer cage 61 automatically slides back into the bearing block 51 along the groove 501 under the guidance of the slider 62. The tested sample continues to rotate. When it rotates to the incomplete tooth 72, the transmission gear 73 on the support shaft 5 meshes with the incomplete tooth 72, thereby driving the support shaft 5 to rotate the bearing block 51 until it flips 180 degrees, achieving the flipping and automatically flipping out the sample above. After the sample is discharged, it can be reloaded for rotation testing.

[0032] In the embodiments of this utility model, please refer to Figures 1 to 4 A driven gear 311 is fixedly sleeved on the outer wall of the bottom end of the sleeve 31. A servo motor 11 is fixedly installed on one side of the bottom end of the sleeve 31 on the detection table 1. A driving gear 111 is fixedly sleeved on the output shaft of the servo motor 11. The driving gear 111 meshes with the driven gear 311, and the servo motor 11 is electrically connected to the control box 9.

[0033] It should be noted that: here, the sleeve 31 is driven by the servo motor 11 to rotate the drive gear 111. The drive gear 111 meshes with the driven gear 311, thereby driving the sleeve 31 to rotate the annular disk 4, rotating the sample in the placement component 6 on the annular disk 4 to one side of the detection window 201, and then pushing it with the pusher 8.

[0034] It should also be noted that the rotation speed of the servo motor 11 needs to match the detection time of the immunoassay analyzer body 2 to achieve intermittent delivery detection.

[0035] In the embodiments of this utility model, please refer to Figures 1 to 4 The driving component 7 includes a lower abutment plate 71 and a transmission gear 73. The lower abutment plate 71 is fixedly installed on the outer side wall of the top of the column 3, and an incomplete tooth 72 is fixedly installed on the side of the lower abutment plate 71 that is away from the detection window 201. There are several transmission gears 73, and the several transmission gears 73 are sleeved on several support shafts 5. When the several transmission gears 73 rotate to the side that is away from the detection window 201, they mesh with the incomplete tooth 72.

[0036] The number of teeth of the incomplete tooth 72 is the same as the number of teeth of the transmission gear 73.

[0037] It should be noted that: when the transmission gear 73 meshes with the incomplete tooth 72, both have the same number of teeth, so that they can rotate 180 degrees when they are in contact. When the transmission gear 73 rotates to the side that is away from the detection window 201, it meshes with the incomplete tooth 72, which drives the support shaft 5 to rotate. After rotating 180 degrees, when it moves away from the side that is away from the detection window 201, the support shaft 5 remains stationary under the action of the damping sleeve shaft. Without external force, it remains stable and does not flip, which facilitates the next meshing with the incomplete tooth 72.

[0038] In this embodiment: a collection bucket 12 is provided below the incomplete tooth 72. The collection bucket 12 is placed on the detection stage 1. In this way, when the sample after detection is driven by the incomplete tooth 72, the driving support shaft 5 drives the bearing block 51 to flip, and the sample on the placement component 6 will automatically flip and fall into the collection bucket 12, thus achieving automatic detachment.

[0039] The working principle of the detection platform for the quantum dot fluorescence immunoassay analyzer provided by this utility model is as follows:

[0040] In use, the sample to be tested is placed in the drawer cage 61. Then, the servo motor 11 drives the drive gear 111 to rotate. The drive gear 111 meshes with the driven gear 311, thereby driving the sleeve 31 to rotate the annular disk 4. The sample in the placement component 6 on the annular disk 4 is rotated to one side of the detection window 201. When it is rotated to be aligned with the detection window 201, the electric telescopic rod 81 is controlled to push the drawer cage 61 above, pushing the drawer cage 61 into the detection window 201 for testing. After testing, the electric telescopic rod 81... After the electric telescopic rod 81 retracts and resets, under the action of the reset spring 64, the drawer cage 61 automatically slides back into the bearing block 51 along the groove 501 under the guidance of the slider 62. The tested sample continues to rotate. When it rotates to the incomplete tooth 72, the transmission gear 73 on the support shaft 5 meshes with the incomplete tooth 72, thereby driving the support shaft 5 to rotate the bearing block 51 until it flips 180 degrees, realizing the flipping and automatically flipping out the sample above. After the sample is discharged, it can be reloaded for rotation testing.

[0041] The circuits and controls involved in this utility model are all existing technologies, and will not be described in detail here.

[0042] The above description is merely an embodiment of this utility model and does not limit the patent scope of this utility model. Any equivalent structural or procedural transformations made based on the content of this utility model specification and drawings, or direct or indirect applications in other related technical fields, are similarly included within the patent protection scope of this utility model.

Claims

1. A quantum dot fluorescence immunoassay analyzer detection platform, comprising: a detection table (1), and an immunoassay analyzer body (2) installed on one side of the detection table (1), the immunoassay analyzer body (2) being provided with a detection window (201) for placing samples for detection; a control box (9) installed on the other side of the detection table (1); characterized in that it further comprises: a stand (3) fixedly installed on the detection table (1) and located on one side of the detection window (201), and a sleeve (31) rotatably installed on the stand (3), a hollow annular disc (4) fixedly installed at the top end of the sleeve (31), a plurality of through grooves (401) uniformly formed on the annular disc (4), a support shaft (5) rotatably installed in each of the through grooves (401) through a damping sleeve, a bearing block (51) fixedly installed on the support shaft (5), a placing assembly (6) for containing samples installed on the upper and lower ends of the bearing block (51), a driving member (7) installed on the outer side wall of the top end of the stand (3) for driving the support shaft (5) to rotate, and a pushing member (8) installed on the top end of the stand (3) for pushing the placing assembly (6) located in front of the detection window (201) into the detection window (201).

2. The detection platform for quantum dot fluorescence immunoassay according to claim 1, characterized in that, A driven gear (311) is fixedly sleeved on the outer side wall of the bottom end of the sleeve (31), a servo motor (11) is fixedly installed on the detection table (1) on one side of the bottom end of the sleeve (31), a driving gear (111) is fixedly sleeved on the output shaft of the servo motor (11), the driving gear (111) is engaged with the driven gear (311), and the servo motor (11) is electrically connected with the control box (9). 3.The detection platform for quantum dot fluorescent immunoassay analyzer according to claim 1, characterized in that, The placing assembly (6) comprises a drawer cage (61), a sliding block (62) is symmetrically installed on the rear end of the drawer cage (61), a groove (501) is formed on the bearing block (51) for sliding cooperation with the sliding block (62), a baffle (63) is fixedly installed at the end of the groove (501), a return spring (64) is fixedly installed on the baffle (63), one end of the return spring (64) away from the baffle (63) extends into the groove (501) and is fixedly connected with the sliding block (62), and the drawer cage (61) is matched with the detection window (201).

4. The detection platform for quantum dot fluorescence immunoassay according to claim 1, characterized in that, The driving member (7) comprises a lower stop disc (71) and a transmission gear (73), the lower stop disc (71) is fixedly installed on the outer side wall of the top end of the stand (3), an incomplete tooth (72) is fixedly installed on one side of the lower stop disc (71) away from the detection window (201), and a plurality of transmission gears (73) are sleeved on a plurality of support shafts (5), the transmission gears (73) are engaged with the incomplete tooth (72) when they are rotated to one side away from the detection window (201).

5. The detection platform for quantum dot fluorescence immunoassay according to claim 4, characterized in that, The number of teeth of the incomplete tooth (72) is the same as the number of teeth of the transmission gear (73).

6. The detection platform for quantum dot fluorescence immunoassay according to claim 4, characterized in that, A collection barrel (12) is arranged below the incomplete tooth (72), and the collection barrel (12) is placed on the detection table (1).

7. The detection platform for quantum dot fluorescence immunoassay according to claim 1, wherein, The pushing member (8) comprises an electric telescopic rod (81), which is fixedly installed at the top end of the stand (3), and the telescopic end of the electric telescopic rod (81) faces one side of the detection window (201) and is flush with the upper placing assembly (6).

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