Mouse metabolism cage

Abstract

The utility model provides a mouse metabolism cage which comprises a mouse containing cage and a support, the mouse containing cage is arranged above the support, the mouse containing cage is divided into a living area and a collecting area through a partition plate, moving running wheels, a feeding trough and a water fountain are arranged in the living area, a leakage net is arranged on the bottom wall of the collecting area, and the bottom wall of the collecting area is provided with a water inlet and a water outlet. And a funnel and a collecting bottle are connected below the mouse containing cage. According to the technical scheme, the mouse containing cage is divided into the living area and the collecting area, urine component changes before and after movement can be detected, urine and excrement can be easily separated, food or water components are prevented from being doped in the urine or the excrement, cross contamination cannot be caused, the living area is provided with the movement running wheels capable of timing, and the rotating speed can be set. Different exercise intensity scenes can be simulated, so that urine components under different exercise intensities can be analyzed. The mouse metabolism cage is simple in structure, convenient to install and clean due to the detachable structure.

Description

Technical Field

[0001] This utility model relates to the field of metabolic cage technology, and in particular to a mouse metabolic cage. Background Technology

[0002] Mice are frequently used in scientific research and teaching experiments, especially in drug experiments where they are used in large quantities. In various drug toxicity tests, it is generally necessary to closely monitor the mice's food and water intake and excrement, and to analyze and record various indicators. This requires experimental cages for collecting mouse excrement. Ordinary cages cause mouse excrement to accumulate inside, making collection difficult. Furthermore, the mixture of feces, urine, and bedding can cause cross-contamination, affecting the accuracy of experimental results. They are also difficult to clean, causing considerable inconvenience to researchers.

[0003] Some existing simple mouse metabolic cages use a mesh screen at the bottom to separate urine and feces. However, this separation method is incomplete, affecting the accuracy of experimental results. Currently available metabolic cages only separate urine and feces once, resulting in incomplete separation. Furthermore, most metabolic cages are complex to install, difficult to clean, and expensive, hindering widespread use. Therefore, there is an urgent need for a simpler mouse metabolic cage that improves the efficiency of feces and urine separation and avoids affecting experimental results. Utility Model Content

[0004] The purpose of this invention is to provide a mouse metabolic cage that can detect changes in urine composition before and after exercise, improve the separation efficiency of mouse feces and urine, and reduce installation steps for easy and quick cleaning.

[0005] According to the purpose of this utility model, this utility model provides a mouse metabolic cage, including a mouse cage and a support. The mouse cage is arranged above the support. The mouse cage is divided into a living area and a collection area by a partition. The living area is equipped with a running wheel, a food trough and a waterer. The bottom wall of the collection area is a mesh screen. A funnel and a collection bottle are connected to the bottom of the mouse cage.

[0006] Furthermore, the rat cage includes a cage body, which is a rectangular parallelepiped structure made of transparent PVC material, and the cage walls are provided with ventilation holes.

[0007] Furthermore, the rotation speed and rotation time of the running wheel are adjusted by a controller.

[0008] Furthermore, the feeding trough is detached from the rat cage.

[0009] Furthermore, the portion where the feeding trough connects to the rat cage is a mesh grid structure.

[0010] Furthermore, the water dispenser is inclined and fixed to the side wall of the rat cage, one end of the water dispenser is located outside the rat cage, the other end of the water dispenser extends into the inside of the rat cage, and the bottom of the water dispenser is provided with a drinking outlet.

[0011] Furthermore, the top two sides of the rat cage are provided with buckles, and the cage cover is fixed to the top of the rat cage by the buckles.

[0012] Furthermore, the bottom of the living area is a PVC board structure.

[0013] Furthermore, the mesh diameter of the sieve is 0.5-0.8 mm.

[0014] Furthermore, the collection bottle has volume markings engraved on its body.

[0015] This invention divides the mouse cage into a living area and a collection area, enabling the detection of changes in urine composition before and after exercise. It easily separates urine and feces, preventing food or water from mixing with urine or feces and avoiding cross-contamination. The living area features a timing and adjustable running wheel to simulate different exercise intensities, allowing for analysis of urine composition under varying exercise levels. The mouse metabolic cage has a simple structure, is easy to install, and its detachable design facilitates cleaning. Attached Figure Description

[0016] To more clearly illustrate the specific embodiments of this utility model or the technical solutions in the prior art, the drawings used in the description of the specific embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are some embodiments of this utility model. For those skilled in the art, other drawings can be obtained from these drawings without creative effort.

[0017] Figure 1 This is a schematic diagram of the structure of an embodiment of the present utility model;

[0018] In the picture: 1. Rat cage; 2. Stand; 3. Divider; 4. Running wheel; 5. Feed trough; 6. Water dispenser; 7. Strainer; 8. Cage lid; 9. Funnel; 10. Collection bottle. Detailed Implementation

[0019] The technical solution of this utility model will be clearly and completely described below with reference to the embodiments. Obviously, the described embodiments are only some embodiments of this utility model, not all embodiments. Based on the embodiments of this utility model, all other embodiments obtained by those skilled in the art without creative effort are within the protection scope of this utility model.

[0020] In the description of this utility model, it should be understood that the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", etc., indicating the orientation or positional relationship are based on the orientation or positional relationship shown in the accompanying drawings, and are only for the convenience of describing this utility model and simplifying the description, and are not intended to indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of this utility model.

[0021] Furthermore, the terms "first" and "second" are used for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of indicated technical features. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of the stated features. In the description of this utility model, "a plurality of" means two or more, unless otherwise explicitly specified. Furthermore, the terms "installed," "connected," and "linked" should be interpreted broadly; for example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; they can refer to the internal connection of two components. Those skilled in the art can understand the specific meaning of the above terms in this utility model based on the specific circumstances.

[0022] Example 1

[0023] like Figure 1 As shown,

[0024] A mouse metabolic cage includes a cage 1 and a support 2. The cage 1 is placed on top of the support 2, which is made of stainless steel. The cage 1 includes a cage body, which is a rectangular structure made of transparent PVC material to facilitate observation of the mouse's vital activities. The cage wall is provided with ventilation holes, which provides good air permeability and can meet the oxygen requirements of the mouse.

[0025] The rat cage 1 is divided into a living area A and a foraging area B by a partition 3. Living area A contains a running wheel 4, a food trough 5, and a water dispenser 6. The running wheel 4 has buttons for adjusting "speed," "time," and "on / off." A long press of the switch turns the running wheel on or off. Pressing the "on / off" button selects the speed or exercise time mode, which can be set using the "speed" and "time" buttons to simulate different exercise intensities and durations. The control method for the running wheel uses a control chip, and its control principle is a conventional control method well-known to those skilled in the art, and will not be elaborated further.

[0026] The food trough 5 in living area A is removable for easy cleaning. The part of the food trough 5 that connects to the cage body is a mesh grid structure to prevent mice from escaping from the food trough. The water dispenser 6 in living area A is tilted at an angle of 10°-20°. The water dispenser 6 is installed on the side wall of the cage body, with one end outside the cage body and the other end extending into the cage body. The water dispenser 6 has a drinking spout. The tilted design of the water dispenser 6 allows water to flow naturally from inside the water dispenser to the drinking spout, making it easy for the mice to drink.

[0027] The top of the cage 1 is equipped with buckles on both sides, and the cage cover 8 is fixed to the top of the cage 1 by the buckles to prevent the mouse from jumping out of the cage.

[0028] The bottom wall of collection area B is a strainer 7, connected to a funnel 9 and a collection bottle 10. The bottom of living area A is made of PVC board to prevent food residue or drinking water from flowing into collection bottle 10 and contaminating the collected specimens. The strainer 7 in collection area B has a mesh diameter of 0.5-0.8 mm, which can filter feces and urine once. The funnel 9 is connected below so that the separated urine flows into collection bottle 10. Collection bottle 10 is marked with volume graduations to measure the amount of urine from the mice.

[0029] In this embodiment, to facilitate the observation of mouse activity, a microenvironment monitoring module is integrated into the top of the cage. This module includes a CO2 sensor, an NH3 sensor, and a temperature and humidity sensor. An active ventilation system can also be installed on the side wall of the cage 1. This system includes a ventilation fan mounted on the cage 1, which operates at a laminar flow rate of 0.5 m / s. HEPA filters are installed in the ventilation holes to filter the air. An electronic balance with an accuracy of 0.01 g is installed at the bottom of the feed trough 5 to monitor food intake in real time.

[0030] This invention divides the rat cage into a living area and a collection area, avoiding the influence of other excrement in the urine on the experimental results. The collection bottle of the collection device is graduated to calculate the urine volume. This invention uses a timing and adjustable speed running wheel to simulate different exercise intensities, thereby analyzing the urine composition under different exercise intensities. This invention has a simple structure and is easy to install; the rat cage and support are detachable for easy cleaning.

[0031] This novel mouse metabolic cage is used in conventional breeding practices. Mice are kept in the living area, and when urine and feces need to be collected, they are placed in the collection area. After urination, the urine filters through the mesh bottom wall, enters a funnel, and flows into a collection tube, thus collecting the urine. This novel mouse metabolic cage has a simple structure, low cost, can detect changes in urine composition before and after exercise, easily separates urine and feces, and avoids food or water contamination, preventing cross-contamination.

[0032] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of this utility model, and are not intended to limit it. Although the utility model has been described in detail with reference to the foregoing embodiments, those skilled in the art should understand that modifications can still be made to the technical solutions described in the foregoing embodiments, or equivalent substitutions can be made to some or all of the technical features therein. Such modifications or substitutions do not cause the essence of the corresponding technical solutions to deviate from the scope of the technical solutions of the embodiments of this utility model.

Claims

1. A mouse metabolic cage, characterized in that, The cage is provided above the support and is divided into a living area and a collection area by a partition, the living area is provided with a running wheel, a feeding trough and a waterer, the bottom wall of the collection area is a mesh, and the cage is connected with a funnel and a collecting bottle below.

2. The mouse metabolic cage of claim 1, wherein, The cage comprises a cage body which is a cuboid in whole and is made of transparent PVC material, and the cage wall is provided with air holes.

3. The mouse metabolic cage of claim 1, wherein, The rotating speed and rotating time of the running wheel are adjusted by a controller.

4. The mouse metabolic cage of claim 1, wherein, The feeding trough is detachably connected with the cage.

5. The mouse metabolic cage of claim 1, wherein, The joint part of the feeding trough and the cage is a grid fence structure.

6. The mouse metabolic cage of claim 1, wherein, The waterer is obliquely arranged and fixed on the side wall of the cage, one end of the waterer is located outside the cage, the other end of the waterer extends into the cage, and the bottom of the waterer is provided with a water inlet.

7. The mouse metabolic cage of claim 1, wherein, The cage cover is fixed on the top of the cage through buckles arranged on both sides of the top of the cage.

8. The mouse metabolic cage of claim 1, wherein, The bottom of the living area is a PVC plate structure.

9. The mouse metabolic cage of claim 1, wherein, The mesh diameter of the mesh is 0.5-0.8mm.

10. The mouse metabolic cage of claim 1, wherein, The bottle body of the collecting bottle is marked with a volume scale.

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