Top-bottom type multi-union blood bag for platelet recovery

Abstract

The utility model discloses a top-bottom type multi-union blood bag for platelet recovery, which comprises a blood collection bag, a blood collection tube and a red blood cell tube are communicated with the bottom of the blood collection bag, and a plasma tube is communicated with the top of the blood collection bag; the red blood cell storage bag is communicated with the blood collection tube, and red blood cell preservation liquid is stored in the red blood cell storage bag; the first plasma storage bag and the second plasma storage bag are both communicated with the plasma tube; and the first easy-to-fold piece and the second easy-to-fold piece are respectively arranged on the blood collection tube and the red blood cell tube. According to the blood bag with the top-bottom type structure, platelets with high purity and yield can be prepared, blood resources can be fully utilized, and the situation of platelet shortage in clinical blood transfusion is relieved; in the preparation process, a liquid medicine bag of the red blood cell preservation liquid does not need to be squeezed, and only one set of squeezing equipment is needed to squeeze the blood collection bag, so that equipment is saved; and when the cryoprecipitate is subsequently prepared, sterile connection is required, so that the operation is simplified.

Description

Technical Field

[0001] This utility model relates to the field of medical device technology, specifically to a top-bottom type multi-unit blood bag for platelet recycling. Background Technology

[0002] Currently, China mainly relies on apheresis platelets to provide the platelets needed for clinical use. The manual method of preparing platelets from whole blood is rarely used, resulting in a persistent platelet shortage, while the large amount of platelets collected from whole blood is not being fully utilized.

[0003] Patent document (201621344880.5, application date 2016.12.09) provides a top-bottom structure blood bag system. After centrifugation, the plasma and red blood cells in the blood collection bag separate into layers. By squeezing the blood collection bag, the upper plasma layer is squeezed into a plasma storage bag, and the red blood cells are then delivered into a red blood cell storage bag by squeezing or gravity flow. In this process, after the plasma and red blood cells are squeezed out from the top and bottom of the blood collection bag respectively, the white membrane layer between the plasma layer and the red blood cell layer is left in the blood collection bag for effective separation and preservation, which is beneficial for the full utilization of platelets in whole blood.

[0004] During use, the following problems were found with the above-mentioned multi-unit blood bags: (1) the drug preservation bag needs to be squeezed to allow the red blood cell preservation solution to flow into the red blood cell storage bag; (2) the plasma in the plasma storage bag needs to be aseptically connected during the subsequent separation and preparation of cryoprecipitate and liquid plasma. These problems lead to cumbersome operation and bring additional risks of contamination. Utility Model Content

[0005] To simplify the separation and preservation of blood components after whole blood centrifugation, this invention provides a top-bottom type multi-unit blood bag for platelet recovery.

[0006] The technical solution adopted by this utility model is as follows: A top-bottom type multi-unit blood bag for platelet recycling includes: a blood collection bag, with a blood collection tube and a red blood cell tube connected at the bottom and a plasma tube connected at the top; a red blood cell storage bag, connected to the blood collection tube, containing red blood cell preservation solution inside; a first plasma storage bag and a second plasma storage bag, both connected to the plasma tube; and a first folding member and a second folding member, respectively disposed on the blood collection tube and the red blood cell tube.

[0007] Preferably, the first folding member is disposed near the blood collection bag, and the second folding member is disposed near the red blood cell storage bag.

[0008] Preferably, the red blood cell tube and the plasma tube are respectively provided with a first flow stop clamp and a second flow stop clamp.

[0009] Preferably, the first plasma storage bag and the second plasma storage bag are connected to the plasma tube via a T-connector.

[0010] Preferably, the three-way connector is provided with a third flow stop clamp and a fourth flow stop clamp on the connecting pipes of the first plasma storage bag and the second plasma storage bag, respectively.

[0011] Preferably, the red blood cell storage bag, the first plasma storage bag, and the second plasma storage bag are all provided with an output port.

[0012] This utility model has the following beneficial effects:

[0013] 1. Providing blood bags with a top-bottom structure, which can produce platelets with high purity and yield, can make full use of blood resources and alleviate the platelet shortage in clinical blood transfusions;

[0014] 2. The process does not require squeezing the red blood cell preservation solution bag; only one set of squeezing equipment is needed to squeeze the blood collection bag, saving equipment.

[0015] 3. Aseptic connection is required during the subsequent preparation of cryoprecipitate, which simplifies the operation. Attached Figure Description

[0016] Figure 1 This is a structural schematic diagram of an embodiment of the present utility model.

[0017] Figure 2 This is a schematic diagram of step one in the operation of this utility model embodiment.

[0018] Figure 3 This is a schematic diagram of step two in the operation of this utility model embodiment.

[0019] Figure 4 This is a schematic diagram of step three in the operation of this utility model embodiment.

[0020] Figure 5 This is a schematic diagram of step four in the operation of this utility model embodiment.

[0021] Figure 6 This is a schematic diagram of step five in the operation of this utility model embodiment.

[0022] Figure 7 This is a schematic diagram of step six in the operation of this utility model embodiment.

[0023] Blood collection bag 1; blood collection tube 2; red blood cell tube 3; plasma tube 4; red blood cell storage bag 5; first plasma storage bag 6; second plasma storage bag 7; first easy-break part 8; second easy-break part 9; first flow stop clamp 10; second flow stop clamp 11; tee connector 12; third flow stop clamp 13; fourth flow stop clamp 14; output socket 15.

[0024] Platelet-poor plasma (PPP); white blood cell (BC); concentrated red blood cells (RCC); red blood cell preservation solution (RBC); red blood cell suspension (RCS); cryoprecipitate; liquid plasma (Plasma). Detailed Implementation

[0025] The present invention will be further described below with reference to the embodiments and accompanying drawings.

[0026] In the embodiments, such as Figure 1 The image shows a top-and-bottom type multi-unit blood bag for platelet recycling, comprising: a blood collection bag 1, with a blood collection tube 2 and a red blood cell tube 3 connected at the bottom, and a plasma tube 4 connected at the top; a red blood cell storage bag 5, connected to the blood collection tube 2, containing red blood cell preservation solution; a first plasma storage bag 6 and a second plasma storage bag 7, both connected to the plasma tube 4; and a first folding member 8 and a second folding member 9, respectively disposed on the blood collection tube 2 and the red blood cell tube 3. Specifically, the first easy-break part 8 is located near the blood collection bag 1, and the second easy-break part 9 is located near the red blood cell storage bag 5; the red blood cell tube 3 and the plasma tube 4 are respectively provided with a first flow stop clamp 10 and a second flow stop clamp 11; the first plasma storage bag 6 and the second plasma storage bag 7 are connected to the plasma tube 4 by a three-way connector 12; the three-way connector 12 and the connecting pipes of the first plasma storage bag 6 and the second plasma storage bag 7 are respectively provided with a third flow stop clamp 13 and a fourth flow stop clamp 14; the red blood cell storage bag 5, the first plasma storage bag 6 and the second plasma storage bag 7 are all provided with an output port 15.

[0027] In this embodiment, as Figures 2-7 The image shows the usage and operating steps of the top-bottom type multi-unit blood bag for platelet recycling, as detailed below.

[0028] Step 1, as follows Figure 2 As shown, after centrifugation, the blood collection bag 1 separates the plasma and red blood cells into layers, forming concentrated red blood cells at the bottom, platelet-poor plasma at the top, and a white membrane layer in the middle.

[0029] Step two, as Figure 3 As shown, by squeezing the blood collection bag 1, the upper layer of plasma with low platelet count is squeezed into the first plasma storage bag 6. Then, concentrated red blood cells are sent into the red blood cell storage bag 5 by squeezing or gravity flow. After the concentrated red blood cells are mixed with the red blood cell preservation solution in the red blood cell storage bag 5, a red blood cell suspension is formed, while the white membrane layer remains in the blood collection bag 1.

[0030] Step 3, as Figure 4 As shown, the red blood cell tube 3 and the plasma tube 4 are sterilely sealed to achieve effective separation and preservation of red blood cell suspension, platelet-poor plasma and white membrane layer.

[0031] Step four, as Figure 5 As shown, the platelet-poor plasma in the first plasma storage bag 6 is rapidly frozen and stored at low temperature. When needed, it is slowly thawed, and cryoprecipitate will form at the bottom of the first plasma storage bag 6.

[0032] Step 5, as Figure 6 As shown, liquid plasma in the first plasma storage bag 6 is transferred to the second plasma storage bag 7 by squeezing or gravity flow, while cryoprecipitate remains in the first plasma storage bag 6.

[0033] Step six, as Figure 7 As shown, the connecting pipe between the first plasma storage bag 6 and the second plasma storage bag 7 is sterilely sealed, ultimately achieving effective separation and preservation of red blood cell suspension, white film layer, cryoprecipitate and liquid plasma.

[0034] This embodiment provides a top-and-bottom structured blood bag. Through the above steps, platelets with high purity and yield can be prepared, and blood resources can be fully utilized to alleviate platelet shortages in clinical transfusions. Furthermore, the red blood cell preservation solution is stored in the red blood cell storage bag 5, so there is no need to squeeze the red blood cell preservation solution bag during preparation; only one set of squeezing equipment is needed to squeeze the blood collection bag 1, saving equipment. In addition, aseptic connection is required for subsequent preparation of cryoprecipitate, simplifying the operation.

[0035] Obviously, the above embodiments of this utility model are merely examples for illustrating the present utility model, and are not intended to limit the implementation of the present utility model. Other obvious variations or modifications derived from the essential spirit of the present utility model still fall within the protection scope of the present utility model.

Claims

1. A top-and-bottom type multi-unit blood bag for platelet recycling, characterized in that, The application relates to a blood collection bag (1) which is connected with a blood collection tube (2) and a red blood cell tube (3) at the bottom and is connected with a plasma tube (4) at the top. A red blood cell storage bag (5) is connected with the blood collection tube (2) and stores red blood cell preservative inside. A first plasma storage bag (6) and a second plasma storage bag (7) are both connected with the plasma tube (4). A first easy-to-break piece (8) and a second easy-to-break piece (9) are respectively arranged on the blood collection tube (2) and the red blood cell tube (3). First and second flow-stopping clamps (10) and (11) are respectively arranged on the red blood cell tube (3) and the plasma tube (4). The first and second plasma storage bags (6) and (7) are connected with the plasma tube (4) through a three-way joint (12). Third and fourth flow-stopping clamps (13) and (14) are respectively arranged on the connecting pipes of the first and second plasma storage bags (6) and (7) and the three-way joint (12). The first easy-to-break piece (8) is arranged close to the blood collection bag (1), and the second easy-to-break piece (9) is arranged close to the red blood cell storage bag (5).

2. The multi-packing blood bag for platelet recovery according to claim 1, wherein The red blood cell storage bag (5), the first plasma storage bag (6) and the second plasma storage bag (7) are all provided with output sockets (15).

3. The multi-packing blood bag for platelet recovery according to claim 1, wherein ​

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