Sample adding system

Abstract

The utility model relates to the technical field of reagent preparation, in particular to a sample adding system which comprises a sample adding mechanism used for placing a reagent container to be added with liquid; the puncturing mechanism is used for puncturing the seal of the reagent container; the pushing mechanism is used for pushing the reagent container in the sample adding mechanism to the puncturing mechanism, and the puncturing mechanism punctures the reagent container and pushes out the reagent in the reagent container. The sample preparation device has the advantages that the problems that in the prior art, manual sample preparation occupies a large amount of labor cost, the error rate is increased, and the personal error of solution preparation is increased are solved, and meanwhile potential safety hazards caused by misoperation of operators are reduced.

Description

TECHNICAL FIELD

[0001] The utility model relates to reagent preparation's technical field especially is with a kind of sample adding system. BACKGROUND

[0002] Sample preparation instrument is the instrument to the sample before on-machine test is handled, after the pre-treatment to sample, sample can be detected and analyzed on measuring instrument. Usually sample needs manual processing, after manual sample adding, reagent adding, shaking, mixing and other complex processing. With the rapid growth of detection demand, the demand for sample pre-treatment also increases greatly, if continue manual sample preparation, it will occupy a lot of human cost and increase the error rate, and also cannot guarantee the consistency of sample processing, and there is certain security risk for operating personnel. Therefore, a fully automated sample preparation instrument for pre-treating sample is needed to replace manual operation and prevent biological contamination and complete various sample preparations. SUMMARY

[0003] In view of the deficiencies in the prior art, the utility model aims to provide a sample adding system, which has the effect of improving the manual sample preparation in the prior art, which occupies a lot of human cost and increases the error rate, and the human error of solution configuration is also increased, and the safety hazards caused by improper operation of operating personnel are also reduced.

[0004] The above utility model of the utility model is realized by the following technical scheme:

[0005] A sample adding system comprises a sample adding mechanism, a piercing mechanism and a pushing mechanism. The sample adding mechanism is used for placing a reagent container to be added. The piercing mechanism is used for piercing the seal of the reagent container. The pushing mechanism is used for pushing the reagent container in the sample adding mechanism to the piercing mechanism, so that the seal of the reagent container is pierced by the piercing mechanism.

[0006] By adopting the above technical scheme, the researcher puts the reagent to be added into the sample adding mechanism, the pushing mechanism pushes the reagent in the sample adding mechanism to the piercing mechanism, the reagent container is pierced by the piercing mechanism, the reagent in the reagent container flows out, and the reagent can be further configured, the human occupation is reduced, and the sample adding can be automatically and quickly performed.

[0007] In a preferred example, the sample adding mechanism can be further configured to comprise a dividing disc assembly for placing the reagent container and a driving assembly for pushing the reagent container in the dividing disc assembly to the piercing position.

[0008] By adopting the above technical scheme, the reagent is automatically pushed to the lower part of the pushing mechanism by the driving assembly, the human participation is reduced, and the work efficiency is improved.

[0009] The utility model discloses in a preferable example can be further configured as: the index plate assembly includes index plate, the needle cylinder frame for supporting index plate and the support rod of setting below needle cylinder frame, be equipped with a plurality of sample holes that set around the center on the index plate, the reagent container sets up in sample hole.

[0010] By adopting the above technical scheme, multiple sample holes can facilitate researchers to assemble multiple reagents at a time and avoid the trouble of frequent reagent addition.

[0011] The utility model discloses in a preferable example can be further configured as: the drive assembly includes the driving piece for driving the rotation of index plate and positioning component, and the positioning component includes the positioning sheet that sets up on index plate and the positioning sensor that cooperates with positioning sheet.

[0012] By adopting the above technical scheme, the drive assembly drives the rotation of index plate, and when the positioning sheet is coupled with the positioning sensor, the rotation of index plate stops, and the reagent is stopped between the pushing mechanism and the puncture mechanism, facilitating the next operation.

[0013] The utility model discloses in a preferable example can be further configured as: the reagent container top port is equipped with the piston, and the piston is slidably arranged in the reagent container.

[0014] By adopting the above technical scheme, the reagent in the reagent container is pushed out by pushing the piston.

[0015] The utility model discloses in a preferable example can be further configured as: the pushing mechanism includes the drive module and the push rod that is driven up and down by the drive module, one end of the push rod is connected with the drive module, the other end abuts the piston, and the drive module drives the piston to push the reagent in the reagent container.

[0016] By adopting the above technical scheme, the drive module drives the push rod and the piston at the end of the push rod to push out the reagent in the reagent container.

[0017] The utility model discloses in a preferable example can be further configured as: the drive module includes the push motor, the threaded rod that is driven to rotate by the push motor, the connecting block that is screw thread connection with the threaded rod, the connecting block is connected with the push rod, and the drive module further includes the vertical guide rail that sets up and the sliding block that is slidably connected with the guide rail, and the sliding block is connected with the connecting block.

[0018] By adopting the above technical scheme, the motor drives the threaded rod to rotate, and due to the restriction of the guide rail and the sliding block, the threaded rod drives the connecting block to move up and down, thereby driving the push rod to move up and down.

[0019] The utility model discloses a further configuration in a preferable example can be: the reagent container includes the pipe body and sets up the pipe along on the pipe body top edge, the pipe body bottom is equipped with the pipe hole, the sample hole is equipped with the buffer component above, the buffer component includes the fixed plate, the fixed plate is opened and is used to pass the hole of reagent container, the pipe along is covered on the fixed plate, the index plate is equipped with the peg, the peg is connected with the fixed plate sliding, the spring is set up on the peg, the spring one end and the fixed plate top touch, the other end and the index plate top touch.

[0020] Through adopting above technical scheme, when driving module drives push rod to move downward, push rod pushes reagent to move downward, and reagent container is moved downward under the push of push rod, and buffer component is pressed downward, until pipe hole contacts puncture mechanism, and bottom seal of reagent container is punctured by puncture mechanism, after reagent is discharged, driving module drives push rod to recover, and buffer piece resets.

[0021] The utility model discloses a further configuration in a preferable example can be: the puncture mechanism includes puncture head, and the puncture head is opened and is equipped with washing hole and the washing channel that communicates with washing hole.

[0022] Through adopting above technical scheme, washing channel communicates washing liquid, and washing liquid enters washing hole through washing channel to wash puncture mechanism.

[0023] The utility model discloses a further configuration in a preferable example can be: the puncture mechanism includes shell, and the puncture head is arranged in the shell.

[0024] Through adopting above technical scheme, after puncture head punctures reagent, reagent enters into shell, and reagent is avoided splashing.

[0025] Summarized above, the utility model discloses at least one beneficial technical effect that includes following:

[0026] 1, index plate positioning and identification, automatic judgment reagent container placement situation, avoid artificial misoperation and lead to push rod to appear mechanical injury under pressure;

[0027] 2, when reagent container, index plate reach puncture position, push rod under pressure initial stage only drive reagent container whole under pressure, until reagent container and puncture mechanism contact, and the bottom seal of reagent container is punctured;

[0028] 3, after adding sample, start adding water, and the purpose of adding water is: wash puncture part puncture head, avoid medicament remaining in puncture mechanism and next operation and cause medicament pollution;The second purpose is: wash inside reagent container, as far as possible the medicament remaining in the inside reagent container is washed out, avoid medicament remaining in reagent container, make the solution component of configuration more accurate. DRAWINGS

[0029] Figure 1is the overall structural schematic diagram of the embodiment;

[0030] Figure 2 is the structural schematic diagram of the sample adding mechanism and the pushing mechanism in the embodiment;

[0031] Figure 3 is the positional relationship schematic diagram of the push rod, the reagent container and the puncture mechanism in the embodiment;

[0032] Figure 4 is the structural schematic diagram of the index plate assembly in the embodiment;

[0033] Figure 5 is the sectional view of the reagent container in the embodiment;

[0034] Figure 6 is the structural schematic diagram of the puncture mechanism in the embodiment;

[0035] Figure 7 is the sectional view of the puncture rod in the embodiment.

[0036] In the figure, 100, sample adding mechanism; 110, index plate assembly; 111, index plate; 112, needle cylinder holder; 113, support rod; 114, sample hole; 115, reagent container; 116, tube body; 117, tube edge; 118, photoelectric sensor; 120, driving assembly; 121, driving piece; 122, positioning component; 123, positioning sheet; 124, positioning sensor; 130, buffer component; 131, fixed plate; 132, pin; 133, spring; 140, pulley; 200, pushing mechanism; 210, driving module; 211, pushing motor; 212, threaded rod; 213, connecting block; 214, guide rail; 215, sliding block; 220, push rod; 230, piston; 300, puncture mechanism; 301, puncture head; 302, cleaning channel; 303, cleaning hole; 310, shell; 311, puncture rod. DETAILED DESCRIPTION

[0037] The utility model will be further explained in detail below in combination with the drawings. EMBODIMENT

[0038] Refer to Figures 1-2 The utility model discloses a kind of sample adding systems, including sample adding mechanism 100, pushing mechanism 200 and puncture mechanism 300, sample adding mechanism 100 is used to place reagent container 115 to be added liquid, puncture mechanism 300 is used to puncture reagent container 115, pushing mechanism 200 is used to push reagent container 115 in sample adding mechanism 100 to puncture mechanism 300, by puncture mechanism 300, reagent container 115 is punctured.

[0039] Refer to Figure 2The adding mechanism 100 comprises an indexing disc assembly 110 for placing reagent containers 115, and a driving assembly 120 for pushing the reagent containers 115 in the indexing disc assembly 110 to a puncture position.

[0040] The indexing disc assembly 110 comprises a circular indexing disc 111, an annular needle cylinder holder 112 for supporting the indexing disc 111, and a support rod 113 arranged below the needle cylinder holder 112 and supporting the needle cylinder holder 112. The indexing disc 111 is provided with eight circular sample holes 114 arranged around the center of the indexing disc 111. The plurality of sample holes 114 can facilitate researchers to assemble multiple reagents at one time and avoid the trouble of frequently adding reagents.

[0041] The reagent containers 115 are placed in the sample holes 114. The reagent containers 115 comprise a cylindrical tube body 116, the top edge of which is provided with an annular tube rim 117, the bottom end of the tube body 116 is conical, and the bottom of the tube body 116 is provided with a tube hole. The tube body 116 is assembled with a prefabricated reagent, and the bottom of the tube hole is sealed. The sealing can be plastic sealing or wax sealing, and the appropriate sealing method is selected according to the properties of the reagent, but the sealing can be pierced by the puncture mechanism 300. The piston 230 is arranged at the top port of the tube body 116. The piston 230 can seal the top port of the tube body 116 on one hand, and cooperate with the driving assembly 120 to push the prefabricated reagent in the reagent container 115 out of the bottom tube hole of the tube body 116 on the other hand.

[0042] The indexing disc assembly 110 further comprises a photoelectric sensor 118 for detecting whether the piston 230 in the reagent container 115 has pushed the reagent in the reagent container 115 out, so as to avoid damage to the reagent container 115 caused by the idling of the driving assembly 120.

[0043] The driving assembly 120 comprises a driving member 121 for driving the rotation of the indexing disc 111, and a positioning component 122. The driving member 121 is an electric motor, the main shaft of which is connected with the center of the indexing disc 111, and the electric motor drives the indexing disc 111 to rotate on the annular needle cylinder holder 112. The positioning component 122 comprises positioning sheets 123 arranged on the indexing disc 111 and a positioning sensor 124 cooperating with the positioning sheets 123. The positioning sheets 123 are arranged on the edge of the indexing disc 111, and each sample hole 114 corresponds to one positioning sheet 123. The driving member 121 drives the rotation of the indexing disc 111, and when the positioning sheet 123 is coupled with the positioning sensor 124, the rotation of the indexing disc 111 is stopped, and the reagent is stopped between the pushing mechanism 200 and the puncture mechanism 300, so as to accurately perform the next operation.

[0044] The sample hole 114 is provided with a buffer component 130, the buffer component 130 comprises a fixed plate 131, the fixed plate 131 is provided with a hole for passing the reagent container 115, the tube along 117 is placed on the fixed plate 131, the index disc 111 is provided with a pin 132, the pin 132 is in sliding connection with the fixed plate 131, the top of the pin 132 is provided with a pin cap, the pin cap prevents the pin 132 from sliding off the fixed plate 131, the pin 132 is sleeved with a spring 133, one end of the spring 133 is in contact with the top of the fixed plate 131, and the other end is in contact with the top of the index disc 111.

[0045] With reference to Figure 4 The needle cylinder frame 112 and the index disc 111 are further provided with a pulley 140, and the pulley 140 is used to reduce the friction force of the index disc 111 when the needle cylinder frame 112 rotates.

[0046] With reference to Figures 2-5 The pushing mechanism 200 comprises a driving module 210 and a push rod 220 driven by the driving module 210 to move up and down, one end of the push rod 220 is connected with the driving module 210, and the other end is provided with a push plate abutting against a piston 230, the driving module 210 drives the piston 230 to push the reagent in the reagent container 115 out.

[0047] The driving module 210 comprises a pushing-out motor 211, a threaded rod 212 driven by the pushing-out motor 211 to rotate, and a connecting block 213 in threaded connection with the threaded rod 212, the connecting block 213 is connected with the push rod 220, and the driving module 210 further comprises a vertical guide rail 214 and a sliding block 215 in sliding connection with the guide rail 214, and the sliding block 215 is connected with the connecting block 213.

[0048] When the driving module 210 drives the push rod 220 to move downward, the push rod 220 pushes the reagent container 115 to move downward, the reagent container 115 is subjected to a pushing force to move downward and press the buffer component 130, until the tube hole contacts the puncture mechanism 300, the bottom sealing of the reagent container 115 is punctured by the puncture mechanism 300, the driving module 210 further drives the push rod 220 to move downward, and the reagent in the reagent container 115 is discharged by the push rod 220 pushing the piston 230. After the reagent is discharged, the driving module 210 drives the push rod 220 to recover, and the buffer component 130 is reset.

[0049] With reference to Figures 6-7The puncture mechanism 300 comprises a puncture head 301 and a shell 310, the puncture head 301 is arranged in the shell 310, the puncture head 301 is provided with a cleaning hole 303 and a cleaning channel 302 communicated with the cleaning hole 303. The shell 310 comprises two annular structures with different diameters, the annular structure with a large diameter is arranged above the annular structure with a small diameter, the puncture head 301 is arranged in the annular structure with a large diameter, a puncture rod 311 is arranged in the annular structure with a large diameter, the puncture head 301 is arranged on the puncture rod 311, and the cleaning channel 302 is arranged on the puncture rod 311 and communicated with an external pipeline, so that the cleaning liquid can be introduced.

[0050] The implementation principle of the embodiment is:

[0051] 1. Artificially placing the reagent container 115 at the reagent container 115 placing position, selecting the reagent container 115 for accurate injection;

[0052] 2. Driving the driving member to drive the index plate 112 to rotate one circle, the scanning position identifying the reagent container 115 placing and using situation, avoiding mechanical injury caused by the push rod 220 pressing down;

[0053] 3. Rotating the index plate 112, rotating the target reagent container 115 to the puncture position;

[0054] 4. The push rod 220 of the reagent container 115 presses down, the bottom sealing cover of the reagent container 115 is contacted with the puncture mechanism 300, and the puncture and sample adding are started;

[0055] 5. After the reagent is discharged, the pure water is cleaned;

[0056] 6. After the cleaning is completed, the push rod 220 is lifted, and the index plate 112 is rotated to the default position.

[0057] The embodiments of the specific embodiment are the preferred embodiments of the utility model, and are not limited to the protection scope of the utility model, so that: all equivalent changes made according to the structure, shape and principle of the utility model should be covered in the protection scope of the utility model.

Claims

1. A sample loading system characterized by: Comprising a sample adding mechanism (100) for placing a reagent container (115) to be added; a puncture mechanism (300) for puncturing the seal of the reagent container (115); a pushing mechanism (200) for pushing the reagent container (115) in the sample adding mechanism (100) to the puncture mechanism (300) to puncture the seal of the reagent container (115) by the puncture mechanism (300).

2. The sample application system of claim 1, wherein: The sample adding mechanism (100) comprises an indexing disc assembly (110) for placing the reagent container (115) and a driving assembly (120) for pushing the reagent container (115) in the indexing disc assembly (110) to a puncture position.

3. The sample application system of claim 2, wherein: The indexing disc assembly (110) comprises an indexing disc (111), a needle cylinder rack (112) for supporting the indexing disc (111), and a support rod (113) arranged below the needle cylinder rack (112), wherein the indexing disc (111) is provided with a plurality of sample holes (114) arranged around the center of the indexing disc (111), and the reagent container (115) is arranged in the sample hole (114).

4. The sample application system of claim 3, wherein: The driving assembly (120) comprises a driving member (121) for driving the indexing disc (111) to rotate and a positioning component (122), wherein the positioning component (122) comprises a positioning sheet (123) arranged on the indexing disc (111) and a positioning sensor (124) matched with the positioning sheet (123).

5. The sample application system of claim 1, wherein: A piston (230) is arranged at the top port of the reagent container (115) and is slidingly arranged in the reagent container (115).

6. The sample application system of claim 5, wherein: The pushing mechanism (200) comprises a driving module (210) and a push rod (220) driven by the driving module (210) to move up and down, wherein one end of the push rod (220) is connected with the driving module (210) and the other end abuts against the piston (230), and the driving module (210) drives the piston (230) to push the reagent in the reagent container (115) out.

7. The sample application system of claim 6, wherein: The driving module (210) comprises an ejection motor (211), a threaded rod (212) driven by the ejection motor (211) to rotate, and a connecting block (213) threadedly connected with the threaded rod (212), wherein the connecting block (213) is connected with the push rod (220), and the driving module (210) further comprises a vertically arranged guide rail (214) and a sliding block (215) slidingly connected with the guide rail (214), and the sliding block (215) is connected with the connecting block (213).

8. The sample application system of claim 3, wherein: The reagent container (115) comprises a tube body (116) and a tube edge (117) arranged at the top edge of the tube body (116), the bottom of the tube body (116) is provided with a tube hole, a buffer part (130) is arranged above the sample hole (114), the buffer part (130) comprises a fixing plate (131), the fixing plate (131) is provided with a hole for passing through the reagent container (115), the tube edge (117) is arranged on the fixing plate (131), the index plate (111) is provided with a pin (132), the pin (132) is in sliding connection with the fixing plate (131), the pin (132) is sleeved with a spring (133), one end of the spring (133) is in top contact with the fixing plate (131), and the other end of the spring (133) is in top contact with the index plate (111).

9. The sample application system of claim 1, wherein: The puncture mechanism (300) comprises a puncture head (301), the puncture head (301) is provided with a cleaning hole (303) and a cleaning channel (302) communicated with the cleaning hole (303).

10. The sample application system of claim 9, wherein: The puncture mechanism (300) comprises a shell (310), and the puncture head (301) is arranged in the shell (310).

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