Liquid storage device of high performance liquid chromatograph

Abstract

The utility model provides a liquid storage device of a high performance liquid chromatograph, which relates to the technical field of liquid storage devices and comprises a liquid chromatograph main body, a fixing frame is fixedly mounted at the top of the liquid chromatograph main body, two rectangular holes are formed in the bottom of the fixing frame, and two liquid storage tanks are fixedly mounted at the top of the fixing frame. And ultrasonic generators are fixedly mounted at the bottoms of the two liquid storage tanks. According to the utility model, under the action of the two bubble sensors, when bubbles exist in liquid in the two liquid storage tanks, the two ultrasonic generators are started through the two controllers, the bubbles in the liquid are gathered or broken by utilizing ultrasonic vibration, and at the same time, the two exhaust valves are opened through the controllers, so that the bubbles in the liquid can be exhausted. The gas in the two liquid storage tanks is discharged along the two exhaust pipes, so that the pressure in the two liquid storage tanks is maintained, the safety of an experiment is ensured, bubbles in the liquid in the two liquid storage tanks can be effectively removed, and the stability and the uniformity of subsequent liquid supply are ensured.

Description

Technical Field

[0001] This utility model relates to the field of liquid storage device technology, and in particular to a liquid storage device for a high performance liquid chromatograph. Background Technology

[0002] High-performance liquid chromatography (HPLC) is an indispensable and important technique in modern analytical chemistry, widely used in pharmaceuticals, biotechnology, environmental monitoring, and food safety. In HPLC analysis, the quality and state of the solvent directly affect the separation effect and analytical results. Furthermore, HPLC operation requires a stable mobile phase to ensure good separation and detection of samples.

[0003] In the existing technology, the liquid storage device of high performance liquid chromatograph is a key component for storing and providing mobile phase. However, when liquid is stored in the storage tank, bubbles are prone to appear in the liquid. Bubbles can interfere with liquid chromatography analysis and cannot ensure the stability and uniformity of the liquid supply. Therefore, it is particularly important to design an efficient liquid storage device for liquid chromatograph. Utility Model Content

[0004] The purpose of this invention is to solve the problem that bubbles easily appear in the liquid when the liquid is stored in the storage tank during the use of existing equipment, and to propose a liquid storage device for high performance liquid chromatograph.

[0005] To achieve the above objectives, the present invention adopts the following technical solution: a high-performance liquid chromatograph (HPLC) storage device, comprising an HPLC main body, a mounting bracket fixedly installed on the top of the HPLC main body, two rectangular holes opened at the bottom of the mounting bracket, two storage tanks fixedly installed on the top of the mounting bracket, an ultrasonic generator fixedly installed at the bottom of each of the two storage tanks, a bubble sensor fixedly installed on one side of the inner wall of each of the two storage tanks, an exhaust pipe fixedly inserted on one side of the outer wall of each of the two storage tanks, an exhaust valve fixedly installed on the outer wall of each of the two exhaust pipes, a tank cover fixedly installed on the top of each of the two tank covers, a drive motor fixedly installed on the top of each of the two drive motors, and a drive rod fixedly installed at the bottom of each of the two drive motors, with the outer wall of the drive rod movably inserted inside the two tank covers.

[0006] Preferably, multiple stirring blades are fixedly installed on the outer walls of both drive rods, and a first temperature sensor is fixedly installed on the other side of the inner wall of both storage tanks.

[0007] Preferably, heaters are fixedly installed on the bottom of the inner walls of both storage tanks, and a first water tank is fixedly installed on the top of the liquid chromatograph body.

[0008] Preferably, two cooling water pipes are fixedly inserted into the top of the first water tank, and the outer walls of the two cooling water pipes are connected to the inside of the two liquid storage tanks, and the outer walls of the two cooling water pipes are fixedly inserted into the inside of the two tank lids.

[0009] Preferably, water pumps are fixedly installed on the outer walls of both cooling water pipes, and the bottoms of the two water pumps are fixedly connected to the top of the first water tank.

[0010] Preferably, a second water tank is fixedly installed on the top of the liquid chromatograph body, and two cooling fans are fixedly installed on the top of the second water tank.

[0011] Preferably, a dustproof net is fixedly installed on the top of the second water tank, and a second temperature sensor is fixedly installed on one side of the inner wall of the second water tank.

[0012] Preferably, a connecting pipe is fixedly inserted into one side of the outer wall of the second water tank, and the output end of the connecting pipe is connected to the interior of the first water tank.

[0013] Preferably, a control valve is fixedly installed on the outer wall of the connecting pipe.

[0014] Preferably, a controller is fixedly installed on the top of the liquid chromatograph body, and one side of the outer wall of the controller is electrically connected to the outer wall of the two drive motors.

[0015] Compared with the prior art, the advantages and positive effects of this utility model are as follows:

[0016] In this invention, two drive motors are activated by a controller, which drive two drive rods and multiple stirring blades to agitate the liquid, preventing precipitation and stratification of components in the liquid and ensuring a uniform mobile phase throughout the analysis process. Two bubble sensors detect the presence of bubbles in the liquid within the two storage tanks. Two ultrasonic generators are activated by the controllers to use ultrasonic vibrations to cause the bubbles to aggregate or burst. Simultaneously, two exhaust valves are opened by the controllers, allowing the gas to escape through the two exhaust pipes. This maintains the pressure within the two storage tanks, ensuring experimental safety and effectively removing bubbles from the liquid within the two storage tanks, thus ensuring the stability and uniformity of subsequent liquid supply.

[0017] In this invention, the temperature of the liquid in the storage tank can be detected by the first temperature sensor. When the liquid temperature is lower than the original set value, the heater is activated by the controller, and the liquid is kept within the normal range under the action of the first temperature sensor. When the liquid temperature is higher than the original set value, the two water pumps are activated by the controller, causing the water in the first water tank to flow along the cooling water pipe, pass through the storage tank to remove the heat adsorbed on it, and then return to the second water tank, achieving a cooling and temperature control effect, maintaining the normal temperature of the liquid, and effectively reducing experimental errors caused by temperature changes. Then, two cooling fans are turned on, and under the action of the second temperature sensor, the water in the second water tank can be cooled until it reaches a certain value. Then, the control valve is opened, allowing the water to return to the first water tank along the connecting pipe, ensuring the recycling of water, saving water resources, and reducing experimental errors caused by liquid temperature changes. Attached Figure Description

[0018] Figure 1 A perspective view of a liquid storage device for a high-performance liquid chromatograph is provided for this utility model;

[0019] Figure 2 A partial front view of a high-performance liquid chromatograph storage device is provided for this utility model;

[0020] Figure 3 A partial bottom view of a liquid storage device for a high-performance liquid chromatograph is provided for this utility model;

[0021] Figure 4 A partial top view of a high-performance liquid chromatograph storage device is provided for this utility model;

[0022] Figure 5 A partially exploded view of a liquid storage device for a high-performance liquid chromatograph is provided for this utility model;

[0023] Figure 6 This invention provides a partially unfolded schematic diagram of a liquid storage device for a high-performance liquid chromatograph.

[0024] Legend:

[0025] 1. Liquid Chromatograph (LC) main body; 2. Mounting frame; 3. Rectangular hole; 4. Storage tank; 5. Ultrasonic generator; 6. Bubble sensor; 7. Exhaust pipe; 8. Exhaust valve; 9. Tank lid; 10. Drive motor; 11. Drive rod; 12. Stirring blade; 13. First temperature sensor; 14. Heater; 15. First water tank; 16. Cooling water pipe; 17. Water pump; 18. Second water tank; 19. Cooling fan; 20. Dustproof net; 21. Second temperature sensor; 22. Connecting pipe; 23. Control valve; 24. Controller. Detailed Implementation

[0026] To better understand the above-mentioned objectives, features and advantages of this utility model, the present utility model will be further described below with reference to the accompanying drawings and embodiments. It should be noted that, unless otherwise specified, the embodiments and features in the embodiments of this application can be combined with each other.

[0027] Many specific details are set forth in the following description in order to provide a full understanding of the present invention. However, the present invention may also be implemented in other ways different from those described herein. Therefore, the present invention is not limited to the specific embodiments disclosed in the following specification.

[0028] Example 1: As Figures 1-6 As shown, this utility model provides a liquid storage device for a high-performance liquid chromatograph (HPLC), including an HPLC body 1, a mounting bracket 2 fixedly installed on the top of the HPLC body 1, two rectangular holes 3 formed at the bottom of the mounting bracket 2, two liquid storage tanks 4 fixedly installed on the top of the mounting bracket 2, an ultrasonic generator 5 fixedly installed at the bottom of each of the two liquid storage tanks 4, a bubble sensor 6 fixedly installed on one side of the inner wall of each of the two liquid storage tanks 4, and an exhaust pipe 7 fixedly inserted into one side of the outer wall of each of the two liquid storage tanks 4. The outer walls of the two exhaust pipes 7 are... An exhaust valve 8 is fixedly installed. A tank cover 9 is fixedly installed on the top of each of the two liquid storage tanks 4. A drive motor 10 is fixedly installed on the top of each of the two tank covers 9. A drive rod 11 is fixedly installed on the bottom of each of the two drive motors 10. The outer wall of the drive rod 11 is movably inserted into the inside of the two tank covers 9. Multiple stirring blades 12 are fixedly installed on the outer wall of each of the two drive rods 11. A first temperature sensor 13 is fixedly installed on the other side of the inner wall of each of the two liquid storage tanks 4. A heater 14 is fixedly installed on the bottom of the inner wall of each of the two liquid storage tanks 4.

[0029] The overall effect of Embodiment 1 is that two liquid storage tanks 4 are installed on the top of the mounting frame 2. Different corresponding liquids are filled into the two liquid storage tanks 4 and connected to the interior of the liquid chromatograph body 1 through external pipes, which can complete the corresponding experimental operations. Then, the drive motors 10 installed on the two tank covers 9 can be started by the controller 24, which drive the two drive rods 11 and multiple stirring blades 12 to stir the liquid, prevent the precipitation and stratification of the components in the liquid in the two liquid storage tanks 4, and ensure that a uniform mobile phase is provided in the subsequent analysis process. Since bubble sensors 6 are installed on one side of the inner wall of each of the two liquid storage tanks 4, the bubble sensors 6 can monitor the liquid in real time. When the bubble sensor 6 detects the presence of bubbles, it sends a signal to the control system and activates the ultrasonic generator 5 installed at the bottom of the two liquid storage tanks 4 via the controller 24. The ultrasonic vibration causes the bubbles in the liquid to gather or burst. At the same time, the controller 24 opens the exhaust valves 8 installed on the two exhaust pipes 7. While removing bubbles, the internal pressure sensor also appropriately discharges gas from the two liquid storage tanks 4, maintaining the internal pressure within the normal range and ensuring the safety of subsequent experiments. This effectively removes bubbles from the liquid in the two liquid storage tanks 4, ensuring the stability and uniformity of the liquid supply from the two liquid storage tanks 4 to the main body of the liquid chromatograph 1.

[0030] Example 2: Figures 2-6 As shown, a first water tank 15 is fixedly installed on the top of the liquid chromatograph body 1. Two cooling water pipes 16 are fixedly inserted into the top of the first water tank 15, and the outer walls of the two cooling water pipes 16 are connected to the interior of the two liquid storage tanks 4. The outer walls of the two cooling water pipes 16 are also fixedly inserted into the interior of the two tank covers 9. Water pumps 17 are fixedly installed on the outer walls of the two cooling water pipes 16, and the bottoms of the two water pumps 17 are fixedly connected to the top of the first water tank 15. A second water tank 18 is fixedly installed on the top of the liquid chromatograph body 1. Two cooling fans 19 are fixedly installed on the top of the first water tank 18. A dustproof net 20 is fixedly installed on the top of the second water tank 18. A second temperature sensor 21 is fixedly installed on one side of the inner wall of the second water tank 18. A connecting pipe 22 is fixedly inserted into one side of the outer wall of the second water tank 18, and the output end of the connecting pipe 22 is connected to the inside of the first water tank 15. A control valve 23 is fixedly installed on the outer wall of the connecting pipe 22. A controller 24 is fixedly installed on the top of the liquid chromatograph body 1, and one side of the outer wall of the controller 24 is electrically connected to the outer wall of the two drive motors 10.

[0031] The overall effect of Embodiment 2 is as follows: Since a first temperature sensor 13 is installed on the other side of the inner wall of each of the two storage tanks 4, the temperature of the liquid inside the two storage tanks 4 can be monitored in real time. Beforehand, the normal temperature values ​​of the two liquids are set in the controller 24. When the two first temperature sensors 13 detect that the internal temperature is lower than the normal value, the controller 24 activates the two heaters 14, which, in conjunction with the two first temperature sensors 13, heat the liquid inside the two storage tanks 4 until it returns to the normal temperature range, at which point the two heaters 14 are turned off. When the two first temperature sensors 13 detect that the internal temperature is higher than the normal value, the controller 24 activates the water pumps 17 installed on the two cooling water pipes 16, causing the cold water in the first water tank 15 to flow along the two cooling water pipes 16. Since the two cooling water pipes 16 are fixedly inserted into the two tank covers 9 and connected to the interior of the two storage tanks 4, the flow of cold water in the two cooling water pipes 16... The movement of the cooling fans 17 removes heat adsorbed on the two cooling water pipes 16 and returns it to the second water tank 18, thus cooling the liquid in the two storage tanks 4. Under the action of the two first temperature sensors 13, the two water pumps 17 are turned off once the liquid temperature returns to the normal range. At this time, the water with heat in the second water tank 18 can be started by the controller 24 to cool the water inside. Under the action of the second temperature sensor 21, when the water in the second water tank 18 drops to the cold water temperature, the controller 24 opens the control valve 23 on the connecting pipe 22, allowing the cooled water to return to the first water tank 15 along the connecting pipe 22, ensuring the circulation of water. Furthermore, the dustproof net 20 effectively prevents foreign objects from falling into the second water tank 18 along the two cooling fans 19 and clogging the connecting pipe 22. Thus, through effective temperature control, experimental errors caused by temperature changes can be reduced.

[0032] Working principle: First, after the two liquids required by the liquid chromatograph body 1 are loaded into the two storage tanks 4, and connected to the interior of the liquid chromatograph body 1 by the external connecting pipe, the controller 24 starts two drive motors 10, which drive two drive rods 11 and multiple stirring blades 12 to agitate the liquids in the two storage tanks 4, ensuring the homogeneity of the solution, preventing precipitation and stratification of components in the liquid, and ensuring a uniform mobile phase throughout the analysis process. Then, through the action of two bubble sensors 6, when bubbles are detected in the two storage tanks 4, the controller 24 starts the two... An ultrasonic generator 5 at the bottom of each of the two liquid storage tanks 4 uses ultrasonic vibration to cause air bubbles in the liquid within the tanks to gather or burst. Simultaneously, a controller 24 opens two exhaust valves 8, allowing some gas from the tanks 4 to escape through two exhaust pipes 7. Under the action of two bubble sensors 6 and an internal pressure sensor, the two exhaust valves 8 automatically close to maintain pressure within the tanks 4, ensuring experimental safety. This effectively removes air bubbles from the liquid within the tanks 4, ensuring the stability and uniformity of subsequent liquid supply. Then, a first temperature sensor... The function of device 13 is as follows: When the liquid temperature in the two storage tanks 4 is lower than the original set value, the controller 24 activates heater 14 to maintain the liquid within the normal range. After a certain period of time, the two heaters 14 are turned off. When the liquid temperature is higher than the original set value, the controller 24 activates two water pumps 17, causing the water in the first water tank 15 to flow along the cooling water pipe 16, then through the storage tank 4 and back to the second water tank 18. This removes the heat adsorbed on the two cooling water pipes 16, achieving a cooling and temperature control effect. Then, the controller 24 turns on two cooling fans 19 to cool the second water tank 18. The water containing heat is cooled down, and under the action of the second temperature sensor 21, when the water temperature in the second water tank 18 drops to a certain value, the controller 24 opens the control valve 23, allowing it to return to the first water tank 15 along the connecting pipe 22, ensuring the recycling of water and saving water resources. Thus, by effectively controlling the temperature, the error in subsequent experiments caused by temperature changes in the liquid in the two storage tanks 4 can be reduced. In general, by maintaining the stability and uniformity of the liquid in the two storage tanks 4, the accuracy of the high-performance liquid chromatography experiment is improved, thereby improving the performance of the high-performance liquid chromatograph storage device.

[0033] The above are merely preferred embodiments of this utility model and are not intended to limit the utility model in any other way. Any person skilled in the art may make changes or modifications to the above-disclosed technical content to create equivalent embodiments for application in other fields. However, any simple modifications, equivalent changes, and modifications made to the above embodiments based on the technical essence of this utility model without departing from the technical solution of this utility model shall still fall within the protection scope of this utility model.

Claims

1. A liquid storage device for a high-performance liquid chromatograph, comprising a liquid chromatograph body (1), characterized in that: The top of the liquid chromatograph body (1) is fixedly mounted with a mounting bracket (2). The bottom of the mounting bracket (2) has two rectangular holes (3). The top of the mounting bracket (2) is fixedly mounted with two liquid storage tanks (4). The bottom of each of the two liquid storage tanks (4) is fixedly mounted with an ultrasonic generator (5). The inner wall of each of the two liquid storage tanks (4) is fixedly mounted with a bubble sensor (6). The outer wall of each of the two liquid storage tanks (4) is fixedly inserted with an exhaust pipe (7). The outer wall of each of the two exhaust pipes (7) is fixedly mounted with an exhaust valve (8). The top of each of the two liquid storage tanks (4) is fixedly mounted with a tank cover (9). The top of each of the two tank covers (9) is fixedly mounted with a drive motor (10). The bottom of each of the two drive motors (10) is fixedly mounted with a drive rod (11). The outer wall of the drive rod (11) is movably inserted into the inside of the two tank covers (9).

2. The high-performance liquid chromatograph storage device according to claim 1, characterized in that: Multiple stirring blades (12) are fixedly installed on the outer walls of both drive rods (11), and a first temperature sensor (13) is fixedly installed on the other side of the inner wall of both storage tanks (4).

3. The high-performance liquid chromatograph storage device according to claim 2, characterized in that: Heaters (14) are fixedly installed on the bottom of the inner walls of the two liquid storage tanks (4), and a first water tank (15) is fixedly installed on the top of the liquid chromatograph body (1).

4. The high-performance liquid chromatograph storage device according to claim 3, characterized in that: Two cooling water pipes (16) are fixedly inserted into the top of the first water tank (15), and the outer walls of the two cooling water pipes (16) are connected to the inside of the two liquid storage tanks (4), and the outer walls of the two cooling water pipes (16) are fixedly inserted into the inside of the two tank covers (9).

5. A high-performance liquid chromatograph storage device according to claim 4, characterized in that: Water pumps (17) are fixedly installed on the outer walls of the two cooling water pipes (16), and the bottoms of the two water pumps (17) are fixedly connected to the top of the first water tank (15).

6. A high-performance liquid chromatograph storage device according to claim 5, characterized in that: A second water tank (18) is fixedly installed on the top of the liquid chromatograph body (1), and two cooling fans (19) are fixedly installed on the top of the second water tank (18).

7. A high-performance liquid chromatograph storage device according to claim 6, characterized in that: A dustproof net (20) is fixedly installed on the top of the second water tank (18), and a second temperature sensor (21) is fixedly installed on one side of the inner wall of the second water tank (18).

8. A high-performance liquid chromatograph storage device according to claim 7, characterized in that: A connecting pipe (22) is fixedly inserted into one side of the outer wall of the second water tank (18), and the output end of the connecting pipe (22) is connected to the interior of the first water tank (15).

9. A high-performance liquid chromatograph storage device according to claim 8, characterized in that: A control valve (23) is fixedly installed on the outer wall of the connecting pipe (22).

10. A high-performance liquid chromatograph storage device according to claim 9, characterized in that: The top of the liquid chromatograph body (1) is fixedly equipped with a controller (24), and one side of the outer wall of the controller (24) is electrically connected to the outer wall of the two drive motors (10).

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