PH value adjusting device

Abstract

The utility model relates to a PH value adjusting device which comprises a tank body and a tank cover, and a lifting mechanism, a stirring mechanism and a water pump are arranged in the tank cover. The fixed end of the lifting mechanism is fixedly arranged in the tank cover, the stirring mechanism is connected to the movable end of the lifting mechanism, a stirring rod of the stirring mechanism penetrates through the tank cover and extends into the tank body, a pipeline joint is arranged on the peripheral wall of the tank cover, the liquid inlet end of the water pump is connected with the inner end of the pipeline joint, and the liquid outlet end of the water pump extends into the tank body through a pipeline; a PH value detector extending into the tank body is arranged at the bottom of the tank cover, and the pipeline joint is externally connected with a regulating liquid container. A lifting type stirring rod structure is introduced, axial movement is synchronously achieved in the rotating process, the liquid layering phenomenon is broken, solutions in different liquid layers generate forced convection, adjusting liquid is rapidly diffused to all depth areas of a container after being injected, the time needed for PH value balancing is greatly shortened, and the problem of misjudgment caused by the fact that the local PH value of a traditional device reaches the standard is effectively solved.

Description

TECHNICAL FIELD

[0001] The utility model relates to the technical field of PH value adjustment, specifically relates to a PH value adjusting device. BACKGROUND

[0002] In the biological field, the accurate regulation of PH value is the key link to ensure the reaction efficiency, product quality and process safety. The traditional PH adjusting device is mainly divided into manual adjustment and electric adjustment, but both have significant technical defects, which is difficult to meet the demand of modern industry for high efficiency and accurate control.

[0003] Manual adjustment depends on manual operation, which needs to add adjusting liquid repeatedly and test PH value intermittently to achieve the control target. This method has the following disadvantages:

[0004] Taking the large production of affinity chromatography as an example, when the protein is eluted with PH 2.5-3.0, Tris buffer needs to be used to neutralize PH to near neutral. In this process, the operator needs to add Tris buffer continuously, and the manual operation error is large, and once the error occurs, the influence on the activity of the antibody is large; the sampling, testing and filling process is time-consuming and laborious, and it is difficult to realize real-time dynamic regulation; limited by operation experience and test frequency, the PH value fluctuation range is large, and it is easy to deviate from the target interval;

[0005] Although the electric adjusting device improves the adjusting efficiency through automatic design, its inherent structure still leads to the following technical bottlenecks:

[0006] Sensor limitation: the existing PH sensor is mostly fixedly installed, and can only monitor the PH value of the local area. When the adjusting liquid is injected from the top, the solution around the sensor may reach the standard in advance due to local rapid mixing, but other liquid layers (especially the bottom layer) in the container still have significant PH gradient due to uneven stirring or liquid viscosity difference;

[0007] Stirring system defect: the installation position of the stirring rod is a preset fixed value, which is difficult to dynamically adjust according to the liquid level, liquid viscosity or reaction stage. This leads to too long time for complete mixing, and increases the risk of local PH value misjudgment;

[0008] Adjusting lag: based on the feedback mechanism of fixed sensor, the system may stop injecting liquid too early due to local PH reaching the standard (leading to low overall PH), or not respond to the PH deviation of deep liquid layer in time (leading to excessive injection of liquid and high overall PH), which eventually causes systematic deviation of the PH value of the mixed uniform solution from the target value.

[0009] The above problems are particularly prominent in large-scale production, which not only increases the consumption of adjusting liquid and the cost of waste liquid treatment, but also may lead to reaction failure due to PH out of control. UTILITY MODEL CONTENT

[0010] The utility model wants to solve the technical problem to provide a PH value adjusting device to overcome the above prior art in the deficiency.

[0011] The utility model discloses a technical scheme that solves the above technical problem: a PH value adjusting device, including jar body and jar cover, be provided with lifting mechanism, stirring mechanism and water pump in jar cover, the fixed end of lifting mechanism is fixedly arranged in jar cover, and the movable end of stirring mechanism is connected to lifting mechanism, and the stirring rod of stirring mechanism penetrates jar cover and extends into jar body, and the peripheral wall of jar cover is provided with pipe joint, and the liquid inlet end of water pump is connected with the inner end of pipe joint, and the liquid outlet end of water pump extends into jar body through pipeline, the bottom of jar cover is provided with the PH value detector that extends into jar body, and the pipe joint is connected with the adjusting liquid container.

[0012] The utility model has the advantages that: the adjusting device introduces the lifting type stirring rod structure, realizes axial movement in the rotation process simultaneously, overcomes the technical bottleneck of the traditional PH value adjusting device, and the stirring rod reciprocates up and down while rotating, breaks the liquid layering phenomenon, and makes different liquid layer solutions produce forced convection.

[0013] The fluid circulation effect of lifting stirring makes the contact area of the PH value detector expand from a fixed point to a three-dimensional space, even if the PH value detector is still fixedly installed, the real-time update rate of the upper and lower liquid layers around the liquid is improved, the monitoring data is more globally representative, and reliable basis is provided for the accurate control of the adjusting liquid injection amount.

[0014] Due to the improved mixing efficiency, the system can reach the target PH value faster and maintain stability, avoiding the situation of excessive liquid injection or insufficient liquid injection after adjustment caused by delayed response of the traditional device.

[0015] By quickly establishing a uniform PH value environment, the existence time of local over-acid / over-base area is reduced, thereby avoiding the denaturation of substances sensitive to over-acid / over-base.

[0016] On the basis of the above technical scheme, the utility model can also be improved as follows.

[0017] Further, the stirring mechanism further comprises a fixed plate, a gas-liquid slip ring, a support, a driving motor, a driving gear and a driven gear, and the fixed plate is fixedly connected to the movable end of the lifting mechanism.

[0018] The connecting rod and the stirring blade of the stirring rod are internally provided with liquid injection channels in communication, the end of the stirring blade is provided with a liquid outlet hole of the liquid injection channel, the fixing plate is provided with a rotating hole, and the lower end of the connecting rod penetrates through the rotating hole and extends into the tank body;

[0019] The fixed end of the gas-liquid slip ring is fixedly arranged on the fixing plate through a support, the liquid inlet of the fixed end of the gas-liquid slip ring is in communication with the liquid outlet end of the water pump, and the liquid outlet of the rotating end of the gas-liquid slip ring is in communication with the upper end inlet of the connecting rod;

[0020] The upper end of the connecting rod is coaxially sleeved with a driven gear, the driving motor is fixedly arranged on the lower end surface of the fixing plate, the output shaft of the driving motor penetrates through the fixing plate and is fixedly connected with the driving gear, and the driving gear is in mesh with the driven gear.

[0021] Further, the stirring mechanism further comprises a bearing, the outer ring of the bearing is fixedly connected with the rotating hole peripheral wall, and the inner ring of the bearing is fixedly connected with the connecting rod.

[0022] Further, the lifting mechanism is a lead screw sliding table mechanism.

[0023] Further, the stirring mechanism further comprises a bearing, the outer ring of the bearing is fixedly connected with the rotating hole peripheral wall, and the inner ring of the bearing is fixedly connected with the connecting rod.

[0024] Further, the height of the inner cylinder is higher than the height of the tank body.

[0025] Further, the upper end surface of the tank cover is provided with a touch display, and the PH value detector and the weighter 11 are electrically connected with the touch display. BRIEF DESCRIPTION OF DRAWINGS

[0026] Fig. 1 It is a cross-sectional structure schematic view of the utility model;

[0027] Fig. 2 It is a structure enlarged view of the lifting mechanism and the stirring mechanism of the utility model.

[0028] In the drawings, the components represented by each reference numeral are listed as follows:

[0029] 1, tank body; 11, weighter; 12, touch display; 2, tank cover; 21, pipeline joint; 22, PH value detector; 3, lifting mechanism; 4, stirring mechanism; 41, stirring rod; 411, connecting rod; 412, stirring blade; 4121, liquid outlet hole; 42, fixing plate; 43, gas-liquid slip ring; 44, support; 45, driving motor; 46, driving gear; 47, driven gear; 5, water pump; 6, inner cylinder. DETAILED DESCRIPTION

[0030] The principles and characteristics of the utility model are described below in combination with the drawings, and the examples are only used to explain the utility model and are not used to limit the scope of the utility model.

[0031] As Figs. 1-2 shown in the embodiment 1, a PH value adjusting device includes a tank body 1 and a tank cover 2, the tank cover 2 is provided with a lifting mechanism 3, a stirring mechanism 4 and a water pump 5; the fixed end of the lifting mechanism 3 is fixedly arranged in the tank cover 2, the stirring mechanism 4 is connected to the movable end of the lifting mechanism 3, the stirring rod 41 of the stirring mechanism 4 penetrates the tank cover 2 and extends into the tank body 1, the tank cover 2 is provided with a pipe joint 21, the inlet end of the water pump 5 is connected with the inner end of the pipe joint 21, the outlet end of the water pump 5 extends into the tank body 1 through a pipe; the bottom of the tank cover 2 is provided with a PH value detector 22 extending into the tank body 1, and the pipe joint 21 is connected with an adjusting liquid container.

[0032] The adjusting device introduces the lifting stirring rod 41 structure, which realizes the axial movement synchronously in the rotating process, significantly overcomes the technical bottleneck of the traditional PH value adjusting device, and the stirring rod 41 reciprocates up and down while rotating, breaks the liquid layering phenomenon, and makes the different liquid layer solutions produce forced convection. Compared with the fixed stirring rod 41, the design makes the adjusting liquid rapidly spread to each depth area of the container after being injected, greatly shortens the time required for PH value balance, and effectively avoids the misjudgment problem caused by the local PH value reaching the standard in the traditional device;

[0033] The fluid circulation effect caused by the lifting stirring makes the contact area of the PH value detector 22 expand from a fixed point to a three-dimensional space. Even if the PH value detector 22 is still fixedly installed, the real-time update rate of the upper and lower liquid layers around the liquid is improved, so that the monitoring data is more globally representative, and a reliable basis is provided for the accurate control of the injection amount of the adjusting liquid;

[0034] Due to the improvement of the mixing efficiency, the system can reach the target PH value faster and maintain it stably, avoiding the situation of excessive injection or insufficient injection after the adjustment caused by the delayed response of the traditional device;

[0035] By rapidly establishing a uniform PH value environment, the existence time of the local over-acid / over-base area is reduced, thereby avoiding the denaturation of substances sensitive to over-acid / over-base.

[0036] The embodiment 2 is a further improvement based on the embodiment 1, and the specific embodiments are as follows:

[0037] The stirring mechanism 4 further includes a fixed plate 42, a gas-liquid slip ring 43, a support 44, a driving motor 45, a driving gear 46 and a driven gear 47, and the fixed plate 42 is fixedly connected to the movable end of the lifting mechanism 3;

[0038] The connecting rod 411 of the stirring rod 41 and the stirring blade 412 are internally provided with liquid injection channels in communication, the end of the stirring blade 412 is provided with a liquid outlet hole 4121 of the liquid injection channel, the fixed plate 42 is provided with a rotating hole, and the lower end of the connecting rod 411 penetrates through the rotating hole and extends into the tank body 1;

[0039] The fixed end of the gas-liquid slip ring 43 is fixedly arranged on the fixed plate 42 through the support 44, the liquid inlet of the fixed end of the gas-liquid slip ring 43 is in communication with the liquid outlet end of the water pump 5, and the liquid outlet of the rotating end of the gas-liquid slip ring 43 is in communication with the upper end inlet of the connecting rod 411;

[0040] The upper end of the connecting rod 411 is coaxially sleeved with a driven gear 47, the driving motor 45 is fixedly arranged on the lower end surface of the fixed plate 42, the output shaft of the driving motor 45 is fixedly connected with the driving gear 46 after penetrating through the fixed plate 42, and the driving gear 46 is meshed with the driven gear 47.

[0041] The scheme adopts the hollow stirring rod 41 design, and the adjusting liquid injection point is arranged at the end of the stirring blade 412, so that the adjusting liquid is distributedly injected, and the adjusting liquid is uniformly released to the whole liquid layer in the form of a fine stream during the rotation and lifting of the stirring rod 41, so that the concentration gradient is greatly eliminated, and the stratification phenomenon is avoided from the source;

[0042] The adjusting liquid release and the stirring movement are synchronized to form a "injection-mixing" cooperative mechanism, the end of the stirring blade 412 is used as the maximum fluid kinetic energy area, the injected adjusting liquid is instantly rolled into the main flow vortex, the mixing efficiency is improved, and the PH value balancing time is reduced;

[0043] Since the adjusting liquid is uniformly distributed in the three-dimensional space, the actual coverage range of the monitoring area of the PH value detector 22 is expanded to the whole container volume, and the PH value obtained by the PH value detector 22 can more quickly reflect the overall solution state, so that the problem of early / late liquid injection misjudgment caused by local compliance of the traditional device is eliminated;

[0044] The hollow stirring rod 41 is integrated with the liquid injection channel, and the independent liquid injection pipeline is omitted, so that the equipment structure is more simple.

[0045] Embodiment 3, this embodiment is a further improvement based on embodiment 2, and the specific implementation is as follows:

[0046] The stirring mechanism 4 further comprises a bearing, the outer ring of the bearing is fixedly connected with the rotating hole peripheral wall, and the inner ring of the bearing is fixedly connected with the connecting rod 411. The friction between the connecting rod 411 and the rotating hole during rotation can be avoided, and the service life of the connecting rod 411 is increased.

[0047] Embodiment 4, this embodiment is a further improvement based on embodiment 1, and the specific implementation is as follows:

[0048] The lifting mechanism 3 is a screw rod sliding table mechanism.

[0049] Embodiment 5, this embodiment is a further improvement on the basis of embodiment 1, which is as follows:

[0050] Further comprising an inner cylinder 6 and a weighter 11, the weighter 11 is arranged on the bottom of the tank body 1, and the inner cylinder 6 is arranged inside the tank body 1 and above the weighter 11. The liquid in the inner cylinder 6 is weighed by the weighter 11, so as to adjust the injection amount of the adjusting liquid according to the proportion, and after the injection amount is close, the injection speed of the adjusting liquid is reduced, which can avoid the one-time injection of the adjusting liquid too fast; in the specific implementation, the spring probe and the metal contact are arranged on the lower edge of the pouring cover 2 and the upper edge of the tank body 1 respectively, the spring probe is electrically connected with the circuit board in the pouring cover, and the metal contact is electrically connected with the weighter 11, so as to avoid external circuit.

[0051] Embodiment 6, this embodiment is a further improvement on the basis of embodiment 1, which is as follows:

[0052] The height of the inner cylinder 6 is higher than the height of the tank body 1. It is convenient to take out the inner cylinder 6.

[0053] Embodiment 7, this embodiment is a further improvement on the basis of embodiment 5, which is as follows:

[0054] The upper end surface of the tank cover 2 is provided with a touch display 12, the PH value detector 22 and the weighter 11 are electrically connected with the touch display 12.

[0055] Although the embodiments of the utility model have been shown and described above, it can be understood that the above-mentioned embodiments are exemplary and cannot be understood as limiting the utility model, and the ordinary skilled in the art can change, modify, replace and modify the above-mentioned embodiments within the scope of the utility model.

Claims

1. A pH adjusting device, characterized by comprising: The utility model provides a kind of automatic stirring and PH value detection tank, including tank body (1) and tank cover (2), lifting mechanism (3), stirring mechanism (4) and water pump (5) are arranged in the tank cover (2);The fixed end of the lifting mechanism (3) is fixedly arranged in the tank cover (2), the movable end of the stirring mechanism (4) is connected to the lifting mechanism (3), the stirring rod (41) of the stirring mechanism (4) penetrates the tank cover (2) and extends into the tank body (1), the tank cover (2) peripheral wall is provided with pipe joint (21), the inner end of the pipe joint (21) is connected with the liquid inlet end of the water pump (5), the liquid outlet end of the water pump (5) is extended into the tank body (1) by pipeline;The bottom of the tank cover (2) is provided with PH value detector (22) extending into the tank body (1), and the pipe joint (21) is connected with the adjusting liquid container.

2. The PH adjusting device according to claim 1, wherein The stirring mechanism (4) further includes a fixed plate (42), a gas-liquid slip ring (43), a bracket (44), a drive motor (45), a drive gear (46), and a driven gear (47), the fixed plate (42) is fixedly connected to the movable end of the lifting mechanism (3). The connecting rod (411) and the stirring blade (412) of the stirring rod (41) are internally provided with an injection channel in communication, the distal end of the stirring blade (412) is provided with an outlet hole (4121) of the injection channel, the fixed plate (42) is provided with a rotating hole, and the lower end of the connecting rod (411) extends into the tank body (1) after penetrating the rotating hole. The fixed end of the gas-liquid slip ring (43) is fixedly arranged on the fixed plate (42) through the bracket (44), the liquid inlet of the fixed end of the gas-liquid slip ring (43) is in communication with the liquid outlet end of the water pump (5), and the liquid outlet of the rotating end of the gas-liquid slip ring (43) is in communication with the upper end inlet of the connecting rod (411). The upper end of the connecting rod (411) is coaxially sleeved with the driven gear (47), the drive motor (45) is fixedly arranged on the lower end surface of the fixed plate (42), the output shaft of the drive motor (45) penetrates the fixed plate (42) and is fixedly connected with the drive gear (46), and the drive gear (46) is engaged with the driven gear (47).

3. A pH adjusting device according to claim 2, characterised in that The stirring mechanism (4) further includes a bearing, the outer ring of the bearing is fixedly connected with the rotating hole peripheral wall, and the inner ring of the bearing is fixedly connected with the connecting rod (411).

4. The pH adjusting device according to claim 1, wherein The lifting mechanism (3) is a lead screw sliding table mechanism.

5. The pH adjusting device of claim 1, wherein Further comprising an inner cylinder (6) and a weighing device (11), the weighing device (11) is arranged at the bottom of the tank body (1), and the inner cylinder (6) is arranged inside the tank body (1) and located on the weighing device (11).

6. The pH adjusting device according to claim 5, wherein The height of the inner cylinder (6) is higher than the height of the tank body (1).

7. The pH adjusting device according to claim 5, wherein The upper end surface of the tank cover (2) is provided with a touch display (12), and the PH value detector (22) and the weighing device (11) are electrically connected with the touch display (12).

Images