Temperature returning device for frozen stem cell resuscitation

Abstract

The utility model relates to the technical field of cell resuscitation, and discloses a temperature returning device for resuscitation of frozen stem cells, which comprises a water bath box, the lower end of the water bath box is fixedly connected with a fixing frame, one side of the fixing frame is fixedly connected with a motor, and the lower end of the water bath box is rotatably connected with a first rotating rod; the output end of the motor is fixedly connected with the lower end of the first rotating rod, the upper end of the first rotating rod is fixedly connected with a connecting plate, one end of the connecting plate is rotatably connected with a second rotating rod, the lower end of the second rotating rod is fixedly connected with a gear, and the lower portion of the interior of the water bath box is fixedly connected with a tooth groove ring. When the device is used for carrying out water bath temperature returning on the cryopreservation tube, the cryopreservation tube can be driven by the shaking table to shake in warm water, so that the temperature returning effect of the cryopreservation tube is better, the temperature returning efficiency of the cryopreservation tube is effectively improved while manpower is saved, and the condition that the local part of the cryopreservation tube is excessively heated is avoided.

Description

TECHNICAL FIELD

[0001] The utility model relates to cell resuscitation technical field especially relates to a kind of rewarming devices for frozen cell resuscitation. BACKGROUND

[0002] The stem cell is usually stored by freezing when storing, and needs to be resuscitated before being taken out for use, which is usually done by water bath.

[0003] After searching, the existing Chinese patent with publication number CN212672769U provides a rewarming device for frozen cell resuscitation, which includes a rewarming resuscitation instrument body and a base. The base has a groove, and the inner bottom of the groove is fixedly connected with a first socket and a second socket. The bottom of the rewarming resuscitation instrument body is fixedly connected with a fixed plate and a fixed block. The bottom of the rewarming resuscitation instrument body is inserted into the groove, and one end of the fixed plate is inserted into the first socket. One end of the fixed block is inserted into the second socket. The upper part of the base has a third slot, and a dust cover is movably inserted into the third slot. The base and the rewarming resuscitation instrument body are movably connected, which facilitates stable placement and removal of the rewarming resuscitation instrument body for maintenance. The dust cover is inserted into the slot of the base for use, effectively preventing the rewarming resuscitation instrument body from being contaminated by dust.

[0004] However, in the prior art, the stem cell rewarming device needs to be held by the operator in 37-degree water for shaking and rewarming, which lasts for one minute, causing the wrist to be soft and causing the shaking efficiency to be low, affecting the rewarming effect of the stem cells. A solution is proposed to solve the problem in the background art. UTILITY MODEL CONTENT

[0005] To make up for the above shortcomings, the utility model provides a rewarming device for frozen cell resuscitation, which aims to improve the stem cell rewarming device, which needs to be held by the operator in 37-degree water for shaking and rewarming, which lasts for one minute, causing the wrist to be soft and causing the shaking efficiency to be low, affecting the rewarming effect of the stem cells.

[0006] In order to achieve the above object, the utility model discloses the following technical scheme: including water bath box, the lower end fixedly connected with the fixed frame of water bath box, one side of the fixed frame is fixedly connected with motor, the lower end of water bath box is rotatably connected with no.

[0007] Further description of the above technical scheme: when the cryopreservation tube loaded with stem cells is water bathed and warmed, the water bath box is provided with warm water with a temperature of degrees, then the cryopreservation tube is fixed on the positioning cylinder, the motor drives the rotation of the first rotating rod, the connecting plate is driven to rotate, the second rotating rod on one end of the rotating connecting plate is driven to move, and the gear below is driven to move in the inner ring part of the gear ring, then the second rotating rod is self-rotated, the shaking table fixed above is rotated, and the cryopreservation tube fixed in the positioning cylinder above is moved.

[0008] Preferably, the two sides of the positioning cylinder are fixedly connected with a first mounting block, and the interiors of the two first mounting blocks are fixedly connected with a first spring.

[0009] Further description of the above technical scheme: the first mounting block can be used to install the first spring in the interior.

[0010] Preferably, one end of the two first springs is fixedly connected with a first clamping rod, and the outer surfaces of the two first clamping rods are respectively slidably connected with the interiors of the two first mounting blocks.

[0011] Further description of the above technical scheme: the first clamping rod can slide in the first mounting block.

[0012] Preferably, one end of the two first clamping rods is respectively fixedly connected with a first clamping plate through the two sides of the positioning cylinder.

[0013] Further description of the above technical scheme: the first clamping plate can clamp and fix the tube body part of the cryopreservation tube under the pushing of the first spring.

[0014] Preferably, the two sides of the positioning cylinder are fixedly connected with a support rod, and the upper sides of one side of the two support rods are fixedly connected with a second mounting block.

[0015] As a further description of the above technical solution: the support rod can be used for mounting the second mounting block.

[0016] Preferably, the inner part of each of the two second mounting blocks is fixedly connected with a second spring, and one end of each of the two second springs is fixedly connected with a second clamping rod.

[0017] As a further description of the above technical solution: the second clamping rod can move in the inner part of the second mounting block and compress the second spring after moving.

[0018] Preferably, the outer surface of each of the two second clamping rods is in sliding connection with the inner part of each of the two second mounting blocks, and one end of each of the two second clamping rods is fixedly connected with a second clamping plate through the upper end of each of the two support rods.

[0019] As a further description of the above technical solution: the second clamping plate can clamp and fix the bottom of the cryopreservation tube under the pushing of the second spring.

[0020] Preferably, the upper end of each of the two second clamping plates is fixedly connected with an outwardly expanding plate, and the two sides of each of the two support rods are fixedly connected with a reinforcing rib.

[0021] As a further description of the above technical solution: the outwardly expanding plate can be used for facilitating the insertion of the cryopreservation tube between the second clamping plates.

[0022] Compared with the prior art, the advantages and positive effects of the utility model lie in,

[0023] 1、 in the utility model, when the cryopreservation tube loaded with stem cells is subjected to water bath rewarming, warm water with a temperature of degrees is arranged in the water bath box, then the cryopreservation tube is fixed on the positioning cylinder, the first rotating rod is driven to rotate by the motor, the connecting plate is driven to rotate, the second rotating rod at one end of the connecting plate is driven to move, the gear below is driven to move in the inner ring part of the gear slot ring, then the second rotating rod is self-rotated, the shaking table fixed above is driven to rotate, the cryopreservation tube fixed in the positioning cylinder above is driven to move, by this method, when the device is subjected to water bath rewarming, the cryopreservation tube is shaken in the warm water by the driving of the shaking table, the rewarming effect of the cryopreservation tube is better, the rewarming efficiency of the cryopreservation tube is effectively improved while manpower is saved, and the condition that the cryopreservation tube is excessively heated in some parts is reduced.

[0024] 2、the utility model discloses, when need to freeze the storage tube fixed on the positioning cylinder, can through directly the bottom contact of freeze the storage tube to the outer expansion board, then press down freeze the storage tube, and its freeze the storage tube will push the two -sided no. 2 clamping plate mutual separation in gradually downward migration process, and after separating, compress no. 2 spring on its no. 2 clamping rod end, and no. 2 spring can push the side of no. 2 clamping plate and the side of freeze the storage tube mutual adhesion under the stress compression, so that its no. 2 clamping plate can hold the pipe body part of freeze the storage tube, then along with the continuous down of freeze the storage tube, and the lower end of its freeze the storage tube will contact no. 1 clamping plate, and the bottom of its freeze the storage tube will push the two -sided no. 1 clamping plate mutual separation, and drive the no. 1 clamping rod of one side to be active and then compress the no. 1 spring on its end, and the no. 1 spring can hold the both sides of no. 1 clamping plate and the bottom of freeze the storage tube, so that its freeze the storage tube can be fixed firmly above the positioning cylinder, by this method, when freeze the storage tube is fixed on the positioning cylinder, it is more convenient and fast, and the stability after clamping is guaranteed, and the efficiency when freeze the storage tube is fixed is improved. BRIEF DESCRIPTION OF DRAWINGS

[0025] Figure 1 A perspective view of a frozen cell recovery rewarming device is provided for the utility model;

[0026] Figure 2 A perspective view of a frozen cell recovery rewarming device is provided for the utility model;

[0027] Figure 3 A perspective view of a frozen cell recovery rewarming device is provided for the utility model;

[0028] Figure 4 A perspective view of a frozen cell recovery rewarming device is provided for the utility model;

[0029] Legend:

[0030] 1, water bath box;2, alveolar ring;3, connecting plate;4, support leg;5, gear;6, no. 2 rotating rod;7, shaking table;8, positioning cylinder;9, fixed frame;10, motor;11, no. 1 rotating rod;12, no. 1 spring;13, no. 1 mounting block;14, no. 1 clamping rod;15, reinforcing rib;16, support rod;17, no. 2 spring;18, no. 2 mounting block;19, no. 2 clamping rod;20, no. 2 clamping plate;21, outer expansion board;22, no. 1 clamping plate. DETAILED DESCRIPTION

[0031] With reference to the accompanying drawings, the technical solutions in the embodiments of the present application will be clearly and completely described below. Obviously, the described embodiments are only part of the embodiments of the present application, rather than all the embodiments of the present application. Based on the embodiments in the present application, all the other embodiments obtained by those skilled in the art without creative efforts fall within the scope of the present application.

[0032] Referring to Figures 1 to 3 An embodiment provided by the present application: including water bath box 1, the lower end of water bath box 1 is fixedly connected with fixed frame 9, one side of fixed frame 9 is fixedly connected with motor 10, the lower end of water bath box 1 is rotatably connected with No. 1 rotating rod 11, the output end of motor 10 is fixedly connected with the lower end of No. 1 rotating rod 11, the upper end of No. 1 rotating rod 11 is fixedly connected with connecting plate 3, one end of connecting plate 3 is rotatably connected with No. 2 rotating rod 6, the lower end of No. 2 rotating rod 6 is fixedly connected with gear 5, the lower part inside water bath box 1 is fixedly connected with gear ring 2, the outer surface of gear 5 is engaged with the outer surface of gear ring 2, the upper end of No. 2 rotating rod 6 is fixedly connected with shaking table 7, the upper end of shaking table 7 is fixedly connected with positioning cylinder 8 on both sides, the periphery of the lower end of water bath box 1 is fixedly connected with supporting leg 4.

[0033] In the embodiment, when the cryopreservation tube loaded with stem cells is water bathed and warmed, warm water with a temperature of 37 degrees is arranged in the water bath box 1, then the cryopreservation tube is fixed on the positioning cylinder 8, the No. 1 rotating rod 11 can be driven to rotate by the motor 10, then the connecting plate 3 is driven to rotate, the rotating connecting plate 3 drives the No. 2 rotating rod 6 on one end to move, and then drives the gear 5 below to move in the inner ring part of the gear ring 2, then the No. 2 rotating rod 6 is self-rotated, then drives the shaking table 7 fixed above to rotate, then drives the cryopreservation tube fixed in the positioning cylinder 8 above to move, by this method, when the cryopreservation tube is water bathed and warmed, the cryopreservation tube can be shaken in the warm water by the driving of the shaking table 7, so that the warming effect of the cryopreservation tube is better, the labor is saved, and the warming efficiency of the cryopreservation tube is effectively improved, and the condition that the cryopreservation tube is locally overheated is avoided.

[0034] Embodiment 2, as Figure 1 , Figure 3 and Figure 4As shown, the two sides of the positioning cylinder 8 are fixedly connected with a first mounting block 13, the interiors of the two first mounting blocks 13 are fixedly connected with a first spring 12, one end of the two first springs 12 is fixedly connected with a first clamping rod 14, the outer surfaces of the two first clamping rods 14 are respectively and slidably connected with the interiors of the two first mounting blocks 13, one end of the two first clamping rods 14 respectively penetrates through the two sides of the positioning cylinder 8 and is fixedly connected with a first clamping plate 22, the two sides of the upper end of the positioning cylinder 8 are fixedly connected with a support rod 16, the upper side of one side of the two support rods 16 is fixedly connected with a second mounting block 18, the interiors of the two second mounting blocks 18 are fixedly connected with a second spring 17, one end of the two second springs 17 is fixedly connected with a second clamping rod 19, the outer surfaces of the two second clamping rods 19 are respectively and slidably connected with the interiors of the two second mounting blocks 18, one end of the two second clamping rods 19 respectively penetrates through the upper end of the two support rods 16 and is fixedly connected with a second clamping plate 20, the upper end of the two second clamping plates 20 is fixedly connected with an outward expansion plate 21, the two sides of the two support rods 16 are fixedly connected with a reinforcing rib 15.

[0035] In this embodiment, when it is needed to fix the cryopreservation tube on the positioning cylinder 8, the bottom of the cryopreservation tube is contacted to the outward expansion plate 21, and then the cryopreservation tube is pressed downward, the cryopreservation tube pushes the two second clamping plates 20 away from each other in the process of gradually moving downward, and compresses the second springs 17 on the end of the second clamping rod 19 after being separated, the second springs 17 can push the side of the second clamping plate 20 and the side of the cryopreservation tube to be in close contact with each other while being compressed, so that the second clamping plate 20 can clamp the tube body of the cryopreservation tube, and then the lower end of the cryopreservation tube contacts the first clamping plate 22, the bottom of the cryopreservation tube pushes the two first clamping plates 22 away from each other, and drives the first clamping rod 14 on one side to move and compress the first spring 12 on the end, the first spring 12 can clamp the two sides of the bottom of the cryopreservation tube by pushing the first clamping plate 22, so that the cryopreservation tube can be fixed on the upper side of the positioning cylinder 8, and the cryopreservation tube can be fixed on the positioning cylinder 8 more conveniently and quickly, and the stability after clamping is ensured, and the efficiency of fixing the cryopreservation tube is improved.

[0036] Working principle: when the freeze tube loaded with stem cells is water bathed, the warm water with the temperature of 37 degrees is arranged in the water bath box 1, then the freeze tube is fixed on the positioning cylinder 8, the first rotating rod 11 is driven to rotate by the motor 10, the connecting plate 3 is driven to rotate, the second rotating rod 6 on one end of the connecting plate 3 is driven to move, the gear 5 below is driven to move in the inner ring part of the gear ring 2, then the second rotating rod 6 is self-rotated, the fixed shaking table 7 above is driven to rotate, the freeze tube fixed in the positioning cylinder 8 is driven to move, through the method, when the freeze tube is water bathed, the freeze tube is shaken in the warm water by the driving of the shaking table 7, the freeze tube has better warming effect, the labor is saved, the warming efficiency of the freeze tube is effectively improved, the situation that the freeze tube is locally overheated is avoided, when the freeze tube needs to be fixed on the positioning cylinder 8, the bottom of the freeze tube is contacted to the outer expansion plate 21, then the freeze tube is pressed downward, the freeze tube pushes the second clamping plates 20 on both sides to separate from each other in the process of moving downward, the second springs 17 on the end of the second clamping rods 19 are compressed after the second clamping plates 20 are separated, the second springs 17 can push the side of the second clamping plates 20 and the side of the freeze tube to be attached to each other while being compressed, the second clamping plates 20 can clamp the tube body part of the freeze tube, then the bottom of the freeze tube pushes the first clamping plates 22 on both sides to separate from each other while the freeze tube continuously moves downward, the bottom of the freeze tube drives the first clamping rod 14 on one side to move and compresses the first spring 12 on the end, the first spring 12 can push the first clamping plates 22 and the two sides of the bottom of the freeze tube to be clamped, so that the freeze tube can be fixed on the top of the positioning cylinder 8, through the method, the freeze tube can be fixed on the positioning cylinder 8 more conveniently and quickly, the stability after clamping is ensured, and the efficiency of fixing the freeze tube is improved.

[0037] Finally, it should be noted that: the above only for the preferred embodiments of the present application, and not for limiting the present application, although the present application has been described in detail with reference to the foregoing embodiments, for those skilled in the art, it still can modify the technical solutions recorded in the foregoing embodiments, or make equivalent replacement for part of the technical features, any modification, equivalent replacement, improvement, etc. made within the spirit and principles of the present application, should be included in the protection scope of the present application.

Claims

1. A thawing and warming device for the recovery of frozen stem cells, comprising a water bath tank (1), characterized in that: The lower end of the water bath box (1) is fixedly connected with a fixing frame (9), one side of the fixing frame (9) is fixedly connected with a motor (10), the lower end of the water bath box (1) is rotatably connected with a first rotating rod (11), the output end of the motor (10) is fixedly connected with the lower end of the first rotating rod (11), the upper end of the first rotating rod (11) is fixedly connected with a connecting plate (3), one end of the connecting plate (3) is rotatably connected with a second rotating rod (6), the lower end of the second rotating rod (6) is fixedly connected with a gear (5), the lower part inside the water bath box (1) is fixedly connected with a gear ring (2), the outer surface of the gear (5) is engaged with the outer surface of the gear ring (2), the upper end of the second rotating rod (6) is fixedly connected with a rocking table (7), the upper end of the rocking table (7) is fixedly connected with a positioning cylinder (8) on both sides, and the lower end of the water bath box (1) is fixedly connected with a supporting leg (4) around.

2. The thawing and warming device for cell recovery according to claim 1, wherein: Both sides of the positioning cylinder (8) are fixedly connected with a first mounting block (13), and the interiors of the two first mounting blocks (13) are fixedly connected with a first spring (12).

3. A thawing cell recovery rewarming device according to claim 2, wherein: One end of each of the two first springs (12) is fixedly connected with a first clamping rod (14), and the outer surfaces of the two first clamping rods (14) are respectively and slidably connected with the interiors of the two first mounting blocks (13).

4. The freeze-dried cell recovery rewarming device of claim 3, wherein: One end of each of the two first clamping rods (14) penetrates through the two sides of the positioning cylinder (8) and is fixedly connected with a first clamping plate (22).

5. The freeze-dried cell recovery rewarming device of claim 1, wherein: Both sides of the upper end of the positioning cylinder (8) are fixedly connected with a supporting rod (16), and the upper sides of one side of the two supporting rods (16) are fixedly connected with a second mounting block (18).

6. A thawing cell recovery rewarming device according to claim 5, wherein: The interiors of the two second mounting blocks (18) are fixedly connected with a second spring (17), and one end of each of the two second springs (17) is fixedly connected with a second clamping rod (19).

7. A thawing cell recovery rewarming device according to claim 6, wherein: The outer surfaces of the two second clamping rods (19) are respectively and slidably connected with the interiors of the two second mounting blocks (18), and one end of each of the two second clamping rods (19) penetrates through the upper end of the two supporting rods (16) and is fixedly connected with a second clamping plate (20).

8. A thawing cell recovery rewarming device according to claim 7, wherein: The upper ends of the two second clamping plates (20) are fixedly connected with an outward expansion plate (21), and the two sides of the two supporting rods (16) are fixedly connected with a reinforcing rib (15).

Images