Oral administration device

Abstract

The utility model discloses an oral administration device, and belongs to the technical field of medical instruments, the oral administration device comprises a patch and an expansion part, the expansion part has a water absorption expansion characteristic, the patch comprises a communication hole, a release cavity communicated with the outside and at least two medicine storage cavities, each medicine storage cavity is communicated with the release cavity through an administration channel, and the communication hole is communicated with the release cavity. Each medicine storage cavity is connected with an expansion part, each expansion part is connected with the outside through a communicating hole, outside water can enter the expansion parts through the communicating holes, and the expansion parts can occupy the space of the medicine storage cavities when absorbing water to expand and extrude fluid in the medicine storage cavities, so that the fluid in the medicine storage cavities enters the release cavity through the medicine feeding channel and finally enters the outside. According to the application with the structure, more than two medicines can be continuously released to an affected part for a long time to treat the affected part.

Description

Technical Field

[0001] This application belongs to the field of medical device technology, specifically an oral drug delivery device. Background Technology

[0002] Cancer is a type of disease caused by the abnormal proliferation of cells in the body. Cancer patients are prone to immune system abnormalities. The oral cavity is the starting point of the digestive tract, and pathogens such as bacteria and viruses from the outside world can easily invade the oral cavity. Cancer patients experience significant psychological stress and are prone to tension and anxiety. Furthermore, some medications for cancer patients can affect immunity, making them more susceptible to oral ulcers. Oral ulcers in cancer patients are difficult to heal, and mouthwashes do not stay in the mouth for long enough to continuously deliver medication to the ulcer. The condition of cancer patients is quite complex, and sometimes a combination of medications is required when treating oral ulcers, thus necessitating specific devices to meet the patient's needs. Utility Model Content

[0003] In order to enable mixed drug delivery and increase the drug delivery time to meet the needs of patients with complex conditions, this application provides an oral drug delivery device.

[0004] An oral drug delivery device includes a patch and an expansion portion. The expansion portion has water absorption and expansion properties. The patch includes a connecting hole, a release chamber communicating with the outside, and at least two drug storage chambers. Each drug storage chamber is connected to the release chamber through a drug delivery channel. Each drug storage chamber is connected to the expansion portion. Each expansion portion is connected to the outside through the connecting hole. External moisture can enter the expansion portion through the connecting hole. When the expansion portion absorbs water and expands, it can occupy the space of the drug storage chamber and squeeze the fluid in the drug storage chamber, so that the fluid in the drug storage chamber enters the release chamber through the drug delivery channel and finally enters the outside.

[0005] In one embodiment of this application, a drug-controlled release membrane is provided at the connection between the release chamber and the outside world.

[0006] In one embodiment of this application, the oral delivery device further includes a water-permeable membrane connected to the expansion portion. The expansion portion is connected to the outside world through the water-permeable membrane, and the water-permeable membrane can control the rate at which water enters the expansion portion.

[0007] In one embodiment of this application, the oral administration device further includes an elastic membrane that seals the connection between the drug storage cavity and the communication hole. The elastic membrane is disposed between the drug storage cavity and the expansion part. When the expansion part absorbs water and expands, the elastic membrane enters the drug storage cavity under the squeezing action of the expansion part.

[0008] In one embodiment of this application, the oral delivery device further includes a rigid frame connected to a communication hole, the rigid frame restricting the expansion portion from expanding outward along the communication hole.

[0009] In one embodiment of this application, the expansion portion is snapped into the patch.

[0010] In one embodiment of this application, the patch further includes a mixing chamber communicating with the release chamber, and each drug delivery channel is communicating with the mixing chamber.

[0011] In one embodiment of this application, a drug-controlled release membrane is provided at the connection between the release chamber and the outside world; the release chamber is flat and extends in a direction parallel to the extension direction of the patch.

[0012] In one embodiment of this application, the bonding surface of the patch is provided with medical adhesive.

[0013] In one embodiment of this application, the bonding surface is provided with release paper.

[0014] The present application using the above structure has at least the following beneficial effects:

[0015] 1. The medication or ointment can be stored in the storage cavity. When the patch is applied to the oral mucosa or tongue, the swelling part can absorb water from saliva. The swelling part absorbs water and expands, squeezing the medication or ointment in the storage cavity, so that the drug can reach the release cavity through the administration channel. Different drugs stored in different storage cavities eventually reach the release cavity and are mixed in the release cavity to treat the patient's oral ulcers.

[0016] 2. A drug-controlled release membrane is provided at the connection between the release chamber and the outside world. The drug-controlled release membrane can control the rate at which the drug in the release chamber reaches the oral ulcer, so that the drug can reach the oral ulcer at a certain rate and provide continuous treatment for the oral ulcer. Attached Figure Description

[0017] Figure 1 This is a schematic structural diagram of one embodiment of the present application;

[0018] Figure 2 This is a schematic diagram of one embodiment of the drug storage chamber in this application;

[0019] Figure 3 This is a schematic diagram illustrating one embodiment of the connection between the drug storage chamber and the drug delivery channel in this application;

[0020] Figure 4 This is a schematic structural diagram of one embodiment of the mixing chamber and the release chamber in this application;

[0021] Figure 5 This is a schematic structural diagram of one embodiment of the expansion portion in this application;

[0022] Figure 6This is a schematic diagram illustrating one embodiment of the connection between the expansion portion and the patch in this application;

[0023] Figure 7 This is a schematic diagram of one embodiment of the drug controlled-release membrane in this application.

[0024] In the picture:

[0025] 101. Patch; 102. Communicating hole; 103. Drug reservoir; 104. Drug delivery channel; 105. Mixing chamber; 106. Release chamber; 107. Adhesive surface;

[0026] 201. Expansion section; 202. Water-permeable membrane; 203. Elastic membrane;

[0027] 301. Drug-controlled release membrane; 302. Rigid framework. Detailed Implementation

[0028] To provide a clearer understanding of the technical features, objectives, and effects of this application, specific embodiments of this application are now described with reference to the accompanying drawings. In the drawings, the same reference numerals indicate components with the same or similar structures but the same function.

[0029] In this document, “illustrative” means “serving as an example, illustration or description”, and any illustration or implementation described herein as “illustrative” should not be construed as a more preferred or advantageous technical solution.

[0030] To keep the drawings concise, only the parts relevant to this application are shown schematically in each drawing, and they do not represent the actual structure of the product. In addition, to make the drawings concise and easy to understand, in some drawings, only one of the components with the same structure or function is shown schematically, or only one of them is labeled.

[0031] Please see Figures 1 to 7 Learn more about this application.

[0032] See Figures 1 to 4 An oral delivery device includes a patch 101 and an expansion portion 201.

[0033] The adhesive surface 107 of the patch 101 is provided with medical adhesive, which facilitates the adhesion of the patch 101 to the affected area. Furthermore, the adhesive surface 107 is provided with release paper to facilitate the transportation of the oral drug delivery device and prevent the adhesive surface 107 from being contaminated. The patch 101 includes a connecting hole 102, a release chamber 106 communicating with the outside, and at least two drug storage chambers 103. Different drug storage chambers 103 can store different types of fluid drugs, and each drug storage chamber 103 is connected to the release chamber 106 through a drug delivery channel 104.

[0034] The expansion part 201 has water absorption and expansion properties. The expansion part 201 can be made of materials such as sodium polyacrylate. Each drug storage cavity 103 is connected to the expansion part 201, and each expansion part 201 is connected to the outside through the connecting hole 102.

[0035] When the patch 101 is applied to the oral mucosa or other locations, moisture from saliva can enter the connecting hole 102, and external moisture can enter the expansion part 201 through the connecting hole 102. When the expansion part 201 absorbs water and expands, it can occupy the space of the drug storage cavity 103 and squeeze the fluid in the drug storage cavity, so that the fluid in the drug storage cavity 103 enters the release cavity 106 through the drug delivery channel 104. Thus, the drug in the drug storage cavity 103 can be mixed in the release cavity 106 and finally enter the outside world, reaching the oral ulcer to treat the oral ulcer.

[0036] See Figure 4 , Figure 7 In one embodiment of this application, a drug-controlled release membrane 301 is provided at the connection between the release chamber 106 and the outside world to control the rate at which the drug in the release chamber 106 reaches the oral ulcer. The drug-controlled release membrane 301 can be a microporous membrane made of EVA material. Of course, it can also be made of other materials as long as it can control the release rate of the drug in the drug storage chamber 103.

[0037] See Figure 4 In one embodiment of this application, the patch 101 further includes a mixing chamber 105 communicating with the release chamber 106. Each drug delivery channel 104 is connected to the mixing chamber 105, so that the drugs in different drug storage chambers 103 can be mixed in the mixing chamber 105 first, then enter the release chamber 106, and finally leave the release chamber 106 to reach the affected area for treatment. The presence of the mixing chamber 105 can improve the mixing effect of the drugs.

[0038] Furthermore, in one embodiment of this application, a drug-controlled release membrane 301 is provided at the connection between the release cavity 106 and the outside. The release cavity 106 is flat and extends in a direction parallel to the extension direction of the patch 101. The drug entering the release cavity 106 continues to move under the pushing action of the expansion portion 201. Due to the obstruction of the drug-controlled release membrane 301, the drug entering the release cavity 106 cannot leave the release cavity 106 directly in a short time. It can only disperse in the release cavity 106 and eventually gradually leave the release cavity 106 under the control of the drug-controlled release membrane 301. The shape of the release cavity 106 can increase the drug release area. Thus, the drugs in different drug storage cavities 103 first enter the mixing cavity 105 for thorough mixing under the action of the expansion portion 201, and then disperse in the surrounding area under the action of the shape of the release cavity 106, so that the drug can fully cover the affected area, increase the drug's effective area, and ensure the therapeutic effect.

[0039] See Figure 1 , Figure 2 , Figure 5 , Figure 6 In one embodiment of this application, the oral drug delivery device further includes a water-permeable membrane 202 connected to the expansion section 201. The expansion section 201 is connected to the outside through the water-permeable membrane 202. The water-permeable membrane 202 can control the rate at which water enters the expansion section 201, thereby preventing the expansion section 201 from expanding rapidly after absorbing water, which would cause all the drug in the drug storage cavity 103 to be squeezed into the release cavity 106 in a short time.

[0040] See Figure 1 , Figure 5 In one embodiment of this application, the oral drug delivery device further includes an elastic membrane 203 that seals the connection between the drug storage cavity 103 and the communication hole 102. The elastic membrane 203 can be made of materials such as rubber or silicone. The elastic membrane 203 is disposed between the drug storage cavity 103 and the expansion part 201. When the expansion part 201 absorbs water and expands, the elastic membrane 203 enters the drug storage cavity 103 under the squeezing action of the expansion part 201, thereby improving the sealing of the drug storage cavity 103 and preventing saliva from entering the drug storage cavity 103 or the drug in the drug storage cavity 103 from entering the outside through the communication hole 102.

[0041] See Figure 1 , Figure 5 In one embodiment of this application, the oral drug delivery device further includes a rigid frame 302 connected to the connecting hole 102. The rigid frame 302 restricts the expansion portion 201 from expanding outward along the connecting hole 102 and restricts the expansion portion 201 from expanding in the direction of the connecting hole 102, so that the expansion portion 201 can squeeze the drug in the drug storage cavity 103 as much as possible, so that it enters the release cavity 106 and improves the emptying degree of the drug storage cavity 103.

[0042] In one embodiment of this application, the expansion portion 201 snaps into the patch 101, see [reference]. Figure 1 , Figure 5 The expansion part 201 is snapped into the patch 101 by the rigid frame 302, which can separate the expansion part 201 and other components from the patch 101, making it convenient to inject drugs into the drug storage cavity 103 through the connecting hole 102 and improving assembly efficiency.

[0043] To better illustrate this application, an example is given of the case where the patch 101 has two drug storage cavities 103.

[0044] See Figure 1 , Figure 2The patch 101 has two drug storage chambers 103, two drug delivery channels 104, a mixing chamber 105 between the two drug storage chambers 103, and a release chamber 106 connected to the mixing chamber 105. The two drug storage chambers 103 are also connected to the outside through two connecting holes 102 respectively.

[0045] See Figure 1 , Figure 5 In one embodiment of this application, the expansion portion 201 is integrally connected with the permeable membrane 202, the elastic membrane 203, and the rigid frame 302. The permeable membrane 202 and the elastic membrane 203 are connected and enclose the expansion portion 201. Furthermore, the assembly formed by the expansion portion 201, the permeable membrane 202, and the elastic membrane 203 is also connected to the rigid frame 302, and is snapped onto the patch 101 through the rigid frame 302. This facilitates the injection of different drugs into the drug storage cavity 103 and improves the assembly efficiency of the components. See [link to relevant documentation]. Figure 1 .

[0046] The permeable membrane 202 can control the rate at which water enters the expansion section 201. When the patch 101 is placed in the oral cavity, the water in the oral cavity can gradually enter the expansion section 201 under the control of the permeable membrane 202, causing the expansion section 201 to absorb water and expand, increasing its volume. Under the restriction of the rigid skeleton 302, the expansion section 201 can only expand into the drug storage cavity 103, causing the elastic membrane 203 to squeeze the drug in the drug storage cavity 103. Different drugs in the two drug storage cavities 103 enter the mixing cavity 105 through the two drug delivery channels 104 for mixing, and then continue to move under the push of the expansion section 201. The mixed drug in the mixing cavity 105 enters the release cavity 106, and is gradually released to the affected area under the action of the drug controlled release membrane 301. Furthermore, since the release cavity 106 is flat, when the drug fills the release cavity 106, this device can obtain a large drug release area.

[0047] Those skilled in the art to which this application pertains will understand that the permeable membrane 202, elastic membrane 203, expansion part 201, and rigid frame 302 in this application can also be independent components. The permeable membrane 202, elastic membrane 203, expansion part 201, and rigid frame 302 can be independently connected to the patch 101. The permeable membrane 202, elastic membrane 203, expansion part 201, and rigid frame 302 can also be freely combined and manufactured into an integrated component according to requirements, as long as the required function can be achieved.

[0048] It should be understood that although this specification describes various embodiments, not every embodiment contains only one independent technical solution. This way of describing the specification is only for clarity. Those skilled in the art should regard the specification as a whole. The technical solutions in each embodiment can also be appropriately combined to form other embodiments that can be understood by those skilled in the art.

[0049] The detailed descriptions listed above are merely specific descriptions of feasible embodiments of this application and are not intended to limit the scope of protection of this application. All equivalent implementations or modifications made without departing from the spirit of the art of this application, such as combinations, divisions or repetitions of features, should be included within the scope of protection of this application.

Claims

1. An oral administration device, characterized in that, The patch includes a patch body and an expansion part, the expansion part has water absorption and expansion characteristics, the patch body includes a communication hole, a release cavity communicating with the outside, and at least two medicine storage cavities, each of the medicine storage cavities is communicated with the release cavity through a medicine delivery channel, each of the medicine storage cavities is connected with the expansion part, each of the expansion parts is connected with the outside through the communication hole, water in the outside can enter the expansion part through the communication hole, and the expansion part can occupy the space of the medicine storage cavity and press the fluid in the medicine storage cavity when the expansion part absorbs water and expands, so that the fluid in the medicine storage cavity enters the release cavity through the medicine delivery channel and finally enters the outside.

2. The oral drug delivery device according to claim 1, wherein a drug controlled release film is arranged at the communication position of the release cavity and the outside.

3. The oral drug delivery device according to claim 1, wherein the oral drug delivery device further includes a water permeable film connected with the expansion part, the expansion part communicates with the outside through the water permeable film, and the water permeable film can control the rate of water entering the expansion part.

4. The oral drug delivery device according to claim 1, wherein the oral drug delivery device further includes an elastic film sealing the communication between the medicine storage cavity and the communication hole, the elastic film is arranged between the medicine storage cavity and the expansion part, and the elastic film enters the medicine storage cavity under the extrusion of the expansion part when the expansion part absorbs water and expands.

5. The oral drug delivery device according to claim 1, wherein the oral drug delivery device further includes a rigid framework connected with the communication hole, and the rigid framework limits the expansion of the expansion part along the communication hole to the outside.

6. The oral drug delivery device according to claim 1, wherein the expansion part is connected with the patch body.

7. The oral drug delivery device according to claim 1, wherein the patch body further includes a mixing cavity communicated with the release cavity, and each of the medicine delivery channels is communicated with the mixing cavity.

8. The oral drug delivery device according to claim 7, wherein a drug controlled release film is arranged at the communication position of the release cavity and the outside; the release cavity is flat and extends in a direction parallel to the extension direction of the patch body.

9. The oral drug delivery device according to claim 1, wherein a medical adhesive is arranged on the adhering surface of the patch body.

10. The oral drug delivery device according to claim 9, wherein a release paper is arranged on the adhering surface.

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