Adjustable polypeptide synthesis tank

Abstract

The utility model discloses an adjustable polypeptide synthesis tank which comprises a tank body, a filter screen and a baffle plate, when solid particulate matters and liquid matters need to be subjected to a synthesis reaction, a lower cover is opened, the filter screen corresponding to a filter hole is arranged, the filter screen and the baffle plate are arranged on an L-shaped annular notch together, and the baffle plate presses a sealing rubber ring; after the reaction is finished, liquid above the baffle is prevented from entering the position below the baffle, then the lower cover can be closed, materials are input for a synthetic reaction, solid particles are blocked above the filter screen, liquid substances are blocked above the baffle, the liquid substances make full contact with the solid particles, and after the reaction is finished, the synthetic substances flow out of the guide-out opening. And the solid particulate matters still remain on the filter screen, so that the liquid cannot be prevented from flowing out.

Description

TECHNICAL FIELD

[0001] The utility model belongs to polypeptide processing equipment technical field relates to an adjustable polypeptide synthesis tank. BACKGROUND

[0002] In the production and processing of polypeptide, usually adopt synthesis tank to realize solid granular material and liquid material to carry out synthesis reaction, the existing synthesis tank usually directly solid granular material and liquid material mixing stirring can, the bottom position of synthesis tank is usually ellipsoid. In practical application, solid granular is easy to gather to the inner lower part of synthesis tank, liquid material is difficult to contact with solid granular material fully, and after reaction, solid granular material will be in the outlet of synthesis tank and block the export of synthesis. SUMMARY

[0003] The utility model discloses a kind of adjustable polypeptide synthesis tanks, effectively solve above-mentioned technical problems.

[0004] The technical scheme adopted by the utility model is as follows:

[0005] A kind of adjustable polypeptide synthesis tank, including tank body, filter screen and baffle, the tank body includes main body and the lower cover that can open and close the bottom of the main body, the inner wall of the lower cover is provided with annular gap with L-shaped cross section, the bottom surface of the annular gap is provided with annular groove, the annular groove is clamped with sealing rubber ring, the filter screen is located above the baffle and is connected with the baffle, the baffle is detachably connected with the annular gap and the bottom surface of the baffle is abutted to the sealing rubber ring, the central portion of the baffle is provided with guide outlet, the guide outlet is connected to the outlet of the lower cover by pipeline.

[0006] Further, buffer space is left between the filter screen and the baffle.

[0007] Further, when the baffle is installed to the bottom surface of the annular gap, the outer side wall of the baffle and the filter screen is abutted to the side surface of the annular gap.

[0008] Further, when the baffle is installed to the bottom surface of the annular gap, the highest point of the outer side wall of the filter screen is lower than the side surface of the annular gap.

[0009] Further, it further includes annular stopper, the cross section of the annular stopper is enclosed by two right angle edges and connecting edge connecting two right angle edges, the two right angle edges are adapted to the L shape of the annular gap.

[0010] Further, the connecting edge is the hypotenuse of right triangle.

[0011] Further, the connecting edge is curve edge, and the curve edge is smoothly connected with the generatrix of the inner wall of the lower cover.

[0012] Compared with the prior art, the beneficial effects of this utility model are as follows:

[0013] This utility model's polypeptide synthesis tank includes a tank body, a filter screen, and a baffle. When a synthesis reaction is required between solid particles and liquid, the lower cover is opened, and a filter screen with corresponding filter holes is inserted. The filter screen and the baffle are installed together on an L-shaped annular notch. The baffle presses down on the sealing ring to prevent liquid above the baffle from entering below it. Then, the lower cover can be closed, and the material can be input for the synthesis reaction. The solid particles will be blocked above the filter screen, and the liquid will be blocked above the baffle. The liquid will fully contact the solid particles. After the reaction is completed, the synthesized product will flow out from the outlet, while the solid particles will remain on the filter screen and will not block the liquid from flowing out. Attached Figure Description

[0014] To more clearly illustrate the technical solutions of the embodiments of this utility model, the drawings used in the embodiments will be briefly described below. It should be understood that the following drawings only show some embodiments of this utility model and should not be regarded as a limitation on the scope. For those skilled in the art, other related drawings can be obtained based on these drawings without creative effort, wherein:

[0015] Figure 1 This is a schematic diagram of the adjustable polypeptide synthesis vessel according to an embodiment of the present invention;

[0016] Figure 2 for Figure 1 Enlarged view of point A in the middle;

[0017] Figure 3 This is a schematic diagram of the installation of the annular stop block according to an embodiment of the present utility model.

[0018] Marked in the image:

[0019] 10-Tank body; 11-Main body; 12-Lower cover; 121-Annular notch; 122-Annular groove; 123-Sealing ring; 124-Annular stop; 1241-Connecting edge;

[0020] 20 - Filter screen; 21 - Buffer space;

[0021] 30 - Baffle; 31 - Outlet. Detailed Implementation

[0022] To make the objectives, technical solutions, and advantages of this utility model clearer, the present utility model will be further described in detail below with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are only for explaining the present utility model and are not intended to limit the present utility model; that is, the described embodiments are only some embodiments of the present utility model, and not all embodiments. The components of the embodiments of the present utility model described and shown in the accompanying drawings can generally be arranged and designed in various different configurations.

[0023] Therefore, the following detailed description of the embodiments of the present invention provided in the accompanying drawings is not intended to limit the scope of the claimed invention, but merely to illustrate selected embodiments of the invention. All other embodiments obtained by those skilled in the art based on the embodiments of the present invention without inventive effort are within the scope of protection of the present invention.

[0024] It should be noted that relational terms such as "first" and "second" are used merely to distinguish one entity or operation from another, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Furthermore, the terms "comprising," "including," or any other variations thereof are intended to cover non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements includes not only those elements but also other elements not expressly listed, or elements inherent to such a process, method, article, or apparatus. Without further limitations, an element defined by the phrase "comprising one..." does not exclude the presence of other identical elements in the process, method, article, or apparatus that includes said element.

[0025] As described in the background section, in the production and processing of peptides, synthesis tanks are typically used to achieve the synthesis reaction between solid particles and liquids. Existing synthesis tanks usually involve directly mixing and stirring the solid particles and liquids, and the bottom of the synthesis tank is typically ellipsoidal. In practical applications, solid particles tend to accumulate in the lower part of the synthesis tank, making it difficult for the liquid to fully contact the solid particles. Furthermore, after the reaction is complete, the solid particles will block the discharge of the synthesized product at the outlet of the synthesis tank.

[0026] Based on this, the inventors created an adjustable peptide synthesis vessel according to this application to solve the above-mentioned technical problems.

[0027] The features and performance of this utility model will be further described in detail below with reference to the embodiments.

[0028] Example

[0029] Please see Figure 1 , Figure 2 ,Figure 3 An adjustable peptide synthesis vessel includes a vessel body 10, a filter screen 20, and a baffle 30. The vessel body 10 includes a main body 11 and a lower cover 12 that can open and close the bottom of the main body 11. Here, the main body 11 refers to the portion of the vessel body 10 that contains most of the material, and it is usually equipped with a stirring mechanism. For example, the lower cover 12 is usually semi-ellipsoidal or conical.

[0030] The inner wall of the lower cover 12 has an L-shaped annular notch 121, and the bottom surface of the annular notch 121 has an annular groove 122, in which a sealing ring 123 is fitted. Here, the L-shaped annular notch 121 is formed by cutting the inner wall of the lower cover 12 with the right-angled side of a right triangle around the central axis of the tank body 10, to facilitate the placement of the sealing ring 123 and the installation of the baffle 30. The filter screen 20 is located above and connected to the baffle 30. For example, the filter screen 20 and the baffle 30 are detachably connected (e.g., snap-fit ​​or bolted) to allow for the selection of an appropriate filter screen 20 based on the particle size of the solid particles. The baffle 30 is detachably connected to the annular notch 121 (e.g., snap-fit ​​or bolted), and the bottom surface of the baffle 30 abuts against the sealing ring 123. The baffle 30 has a central outlet 31, which is connected to the outlet of the lower cover 12 via a pipe. For example, the top surface of the baffle 30 can converge at the outlet 31 to facilitate the discharge of the compound.

[0031] The polypeptide synthesis tank of this invention includes a tank body 10, a filter screen 20, and a baffle 30. When a synthesis reaction is required between solid particles and liquid, the lower cover 12 is opened, and the filter screen 20 with corresponding filter holes is inserted. The filter screen 20 and the baffle 30 are installed together on an L-shaped annular notch 121. The baffle 30 presses down on the sealing ring 123 to prevent liquid above the baffle 30 from entering below the baffle 30. Then the lower cover 12 can be closed, and the material can be input for the synthesis reaction. The solid particles will be blocked above the filter screen 20, and the liquid will be blocked above the baffle 30. The liquid will fully contact the solid particles. After the reaction is completed, the synthesized product will flow out from the outlet 31, and the solid particles will remain on the filter screen 20 without blocking the liquid from flowing out.

[0032] In another embodiment, a buffer space 21 is provided between the filter 20 and the baffle 30. The buffer space 21 contains the liquid material used as raw material, which facilitates full contact and reaction.

[0033] In another embodiment, when the baffle 30 is installed on the bottom surface of the annular notch 121, the outer sidewalls of both the baffle 30 and the filter screen 20 abut against the sidewall of the annular notch 121. This arrangement effectively prevents liquid residue from remaining between the baffle 30 and the sidewall of the annular notch 121. Furthermore, when the baffle 30 is installed on the bottom surface of the annular notch 121, the highest point of the outer sidewall of the filter screen 20 is lower than the sidewall of the annular notch 121, further preventing liquid residue from remaining between the baffle 30 and the sidewall of the annular notch 121.

[0034] In another embodiment, an annular stop 124 is also included. The cross-section of the annular stop 124 is formed by two right-angled sides and a connecting edge 1241 connecting the two right-angled sides. The two right-angled sides are adapted to the L-shape of the annular notch 121. This configuration allows the annular notch 121 to be blocked by the annular stop 124 when the filter 20 is not needed to elevate the position of solid particles, thus preventing interference with the completion of the conventional reaction. For example, the connecting edge 1241 is the hypotenuse of a right triangle. Alternatively, the connecting edge 1241 can be a curved edge that smoothly transitions to the generatrix of the inner wall of the lower cover 12, resulting in a smooth transition and reduced wear.

[0035] The above description is only a preferred embodiment of the present utility model and is not intended to limit the scope of protection of the present utility model. Any modifications, equivalent substitutions and improvements made by those skilled in the art within the spirit and principles of the present utility model should be included within the scope of protection of the present utility model.

Claims

1. An adjustable polypeptide synthesis pot, characterized in that, The filter screen is located above the baffle and connected with the baffle, the baffle is detachably connected with the annular gap, and the bottom surface of the baffle abuts against the sealing rubber ring, the baffle is provided with a guide outlet in the center, and the guide outlet is connected to the outlet of the lower cover through a pipeline.

2. The tunable polypeptide synthesis pot of claim 1, wherein, The filter screen and the baffle leave a buffer space therebetween.

3. The tunable polypeptide synthesis pot of claim 2, wherein, When the baffle is installed to the bottom surface of the annular gap, the outer side walls of both the baffle and the filter screen abut against the side surface of the annular gap.

4. The tunable polypeptide synthesis pot of claim 3, wherein, When the baffle is installed to the bottom surface of the annular gap, the highest point of the outer side wall of the filter screen is lower than the side surface of the annular gap.

5. The tunable polypeptide synthesis pot of any one of claims 1-4, wherein, Further comprising an annular stopper, the cross section of the annular stopper is enclosed by two right angle edges and a connecting edge connecting the two right angle edges, and the two right angle edges are matched with the L shape of the annular gap.

6. The tunable polypeptide synthesis pot of claim 5, wherein, The connecting edge is the hypotenuse of a right triangle.

7. The adjustable polypeptide synthesis pot of claim 5, wherein, The connecting edge is a curved edge, and the curved edge is smoothly connected with the generatrix of the inner wall of the lower cover.

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