Transdermal patch in-vitro test treatment device

By designing an in vitro testing and processing device for transdermal patches, a driving mechanism and adhesive rollers are used to achieve stable peeling and sorting of transdermal patches, solving the subjective problem of transdermal patch adhesion testing and improving testing accuracy and product quality.

CN224109307UActive Publication Date: 2026-04-10TIHE (HANGZHOU) PHARM TECH SERVICE CO LTD
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2025-01-16
Publication Date
2026-04-10

AI Technical Summary

Technical Problem

Existing methods for testing the adhesion of transdermal patches are highly subjective, leading to misjudgments and affecting drug delivery and patient compliance.

Method used

Design a transdermal patch in vitro testing and processing device. The device uses a drive mechanism to move the adhesive roller to achieve stable peeling and comparison of transdermal patches. Transdermal patches with poor adhesion are first lifted up for classification.

Benefits of technology

This improves the objectivity and accuracy of transdermal patch adhesion testing, preventing transdermal patches with poor adhesion from being mistakenly judged as qualified products, ensuring that drugs are delivered at the expected rate and dosage, and improving product quality and safety.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model relates to the technical field of transdermal patches, and discloses a transdermal patch in-vitro test processing device which comprises a working table, a test stripping plate is fixedly connected to the upper surface of the working table, a transdermal patch body is bonded to the upper surface of the test stripping plate, an edge groove is formed in the upper surface of the working table, and the edge groove is communicated with the test stripping plate. The driving motor drives the lead screw to rotate, so that the limiting sliding frame linearly moves along the sliding groove plate, the limiting sliding frame drives the pushing frame and the gluing roller on the pushing frame to move along with the pushing frame, due to the bonding relation between the transdermal patch and the gluing roller and the test stripping plate, the gluing roller drives one side of the transdermal patch to move, and the transdermal patch is stripped from the test stripping plate. When the adhesive roller drives the three different transdermal patches to be peeled off at the same time, the transdermal patch body with the poor adhesive force tilts firstly, a worker can directly compare the transdermal patches and classify the transdermal patches with the poor adhesive force, the overall product quality is improved, and the problem that the transdermal patches with the poor adhesive force are prone to falling off when a user uses the transdermal patches with the poor adhesive force is solved.
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Description

TECHNICAL FIELD

[0001] The utility model relates to the technical field of transdermal patch, especially to a transdermal patch in-vitro test processing device. BACKGROUND

[0002] As an important drug delivery method, transdermal patch has been widely used in the medical field in recent years. Transdermal patch can make the drug penetrate the skin into the blood circulation at a relatively constant rate, avoiding the problems of gastrointestinal degradation and liver first-pass effect that may be faced by oral administration, and also has the advantages of improving patient compliance, etc.

[0003] In the research and production process of transdermal patch, the adhesion of transdermal patch needs to be strictly tested and evaluated. The traditional detection method is mostly through simple manual operation, such as directly peeling off the transdermal patch by hand to judge its adhesion. This method has great subjectivity. Different operators may draw different conclusions about the adhesion of transdermal patch due to differences in force, peeling angle, etc. If the operator makes a mistake, the transdermal patch with poor adhesion may be misjudged as a qualified product, which may easily fall off prematurely during the subsequent use of the patient, not only interfering with the normal delivery of the drug at the expected rate and dose, but also possibly greatly reducing the treatment effect and failing to achieve the expected treatment purpose. SUMMARY

[0004] To solve the above technical problems, the utility model provides a transdermal patch in-vitro test processing device.

[0005] The utility model adopts the following technical scheme: a transdermal patch in-vitro test processing device, including the workbench, the upper surface of the workbench is fixedly connected with the test peeling plate, the upper surface of the test peeling plate is bonded with the transdermal patch body, the upper surface of the workbench is equipped with the side groove, the inside of the side groove is connected with the extension block in sliding mode, the surface of the extension block is fixedly connected with the push frame, the surface of the push frame is fixedly connected with the adhesive roller, the upper surface of the workbench is fixedly connected with the support frame, the surface of the support frame is fixedly connected with the drive mechanism.

[0006] Through the above technical scheme, the adhesion of different transdermal patch bodies can be directly compared, the transdermal patch bodies with poor adhesion can be classified and processed, the product quality is improved, and the problem of easy falling off caused by using transdermal patch with poor adhesion is avoided.

[0007] As a further improvement of the above scheme, the drive mechanism includes a sliding groove plate, the upper surface of the sliding groove plate is fixedly connected with a drive motor, the output end of the drive motor is fixedly connected with a lead screw, the surface of the lead screw is threadedly connected with a limit sliding frame, and the surface of the lead screw is rotatably connected with a support shaft seat.

[0008] The above technical solution drives the movement of the limiting slide, thereby providing power for the linear movement of the pusher and ensuring a stable and orderly peeling process of the transdermal patch.

[0009] As a further improvement to the above solution, the slide plate is fixedly connected to the surface of the support frame.

[0010] The above technical solution enables the drive mechanism and the support frame to form a stable connection structure, which helps to maintain the integrity of the entire device structure and prevents malfunctions due to structural instability during the peeling process of the transdermal patch.

[0011] As a further improvement to the above solution, the limiting slide is fixedly connected to the surface of the pusher frame, and the limiting slide is slidably connected to the inside of the slide plate.

[0012] The above technical solution enables the adhesive roller to move along a predetermined trajectory, ensuring the accuracy of the transdermal patch peeling operation.

[0013] As a further improvement to the above solution, the support shaft seat is fixedly connected to the upper surface of the slide plate.

[0014] The above technical solution enhances the stability of the lead screw rotation, thereby ensuring the smooth peeling of the transdermal patch.

[0015] As a further improvement to the above solution, the transdermal patch body is adhered to the surface of the adhesive roller.

[0016] The above technical solution enables the adhesive roller to effectively drive the transdermal patch body to peel off.

[0017] As a further improvement to the above solution, a control panel is fixedly connected to the surface of the workbench.

[0018] Compared with the prior art, the beneficial effects of this utility model are as follows:

[0019] This invention uses a drive motor to rotate a lead screw, causing a limiting slide to move linearly along a slide rail. The limiting slide then drives a pusher frame, on which the adhesive roller moves accordingly. Due to the adhesion between the transdermal patch, the adhesive roller, and the test peel plate, the adhesive roller moves one side of the transdermal patch, peeling it off from the test peel plate. When the adhesive roller simultaneously peels off three different transdermal patches, the patch with the weakest adhesion will be the first to lift up. This allows for direct comparison, enabling the categorization and processing of the poorly adhesive patches, thus improving overall product quality and preventing users from easily detaching the patch due to poor adhesion. Attached Figure Description

[0020] Figure 1 This is a schematic diagram of the overall structure of this utility model;

[0021] Figure 2 It is a structural schematic view of the driving mechanism of the utility model;

[0022] Figure 3 It is a structural schematic view of the test peeling plate of the utility model;

[0023] Figure 4 It is a structural schematic view of the viscose roller of the utility model.

[0024] Main symbol explanation:

[0025] 1, workbench, 2, test peeling plate, 3, transdermal patch body, 4, side groove, 5, extension block, 6, push frame, 7, viscose roller, 8, support frame, 9, driving mechanism, 901, sliding groove plate, 902, driving motor, 903, screw rod, 904, limiting sliding bracket, 905, support shaft seat, 10, control panel. Specific implementation

[0026] Next, the utility model is further described in combination with the drawings and specific implementation, and it should be noted that the following described embodiments or technical features can be combined to form new embodiments without conflict.

[0027] Embodiment:

[0028] Please combine Figures 1-4 The transdermal patch in-vitro test processing device of the embodiment includes a workbench 1, the upper surface of the workbench 1 is fixedly connected with a test peeling plate 2, the upper surface of the test peeling plate 2 is bonded with a transdermal patch body 3, the upper surface of the workbench 1 is provided with a side groove 4, the inside of the side groove 4 is slidably connected with an extension block 5, the surface of the extension block 5 is fixedly connected with a push frame 6, the surface of the push frame 6 is fixedly connected with a viscose roller 7, the upper surface of the workbench 1 is fixedly connected with a support frame 8, the surface of the support frame 8 is fixedly connected with a driving mechanism 9, the transdermal patch body 3 is bonded on the test peeling plate 2, the extension block 5 slides in the side groove 4, drives the push frame 6 connected therewith to move, and the viscose roller 7 on the push frame 6 also moves. Since the lower surface of the transdermal patch body 3 is bonded on the test peeling plate 2, the viscose roller 7 moves and drives one side of the transdermal patch body 3 to move, so that the transdermal patch body 3 is peeled off from the surface of the test peeling plate 2. And three test peeling plates 2 are arranged, when the viscose roller 7 simultaneously drives three different transdermal patch bodies 3 to peel off, the transdermal patch body 3 with poor adhesion will be the first to be lifted, facilitating personnel observation and comparison.

[0029] The driving mechanism 9 comprises a sliding groove plate 901, the upper surface of the sliding groove plate 901 is fixedly connected with a driving motor 902, the output end of the driving motor 902 is fixedly connected with a lead screw 903, the surface of the lead screw 903 is threadedly connected with a limiting sliding frame 904, the surface of the lead screw 903 is rotatably connected with a support shaft seat 905, the driving motor 902 in the driving mechanism 9 works, and the output end drives the lead screw 903 to rotate. The lead screw 903 is threadedly connected with the limiting sliding frame 904, and the lead screw 903 rotates on the support shaft seat 905, when the lead screw 903 rotates, the limiting sliding frame 904 moves linearly along the sliding groove plate 901.

[0030] The sliding groove plate 901 is fixedly connected to the surface of the support frame 8, and is fixed on the support frame 8, thereby providing a support and mounting position for the driving motor 902, the lead screw 903 and other components, and ensuring the stability of the overall structure of the driving mechanism 9.

[0031] The limiting sliding frame 904 is fixedly connected to the surface of the pushing frame 6 and is slidably connected to the inside of the sliding groove plate 901, when the limiting sliding frame 904 slides in the sliding groove plate 901, due to the fixed connection relationship with the pushing frame 6, the pushing frame 6 can be driven to move linearly, and the adhesive roller 7 can be stably moved, thereby driving the transdermal patch body 3 to be peeled off.

[0032] The support shaft seat 905 is fixedly connected to the upper surface of the sliding groove plate 901 and is fixed on the upper surface of the sliding groove plate 901, thereby providing a rotating support point for the lead screw 903, ensuring the stability of the lead screw 903 during rotation, and enabling the lead screw 903 to normally cooperate with the limiting sliding frame 904, thereby realizing the linear movement of the limiting sliding frame 904.

[0033] The transdermal patch body 3 is attached to the surface of the adhesive roller 7, when the adhesive roller 7 moves, the transdermal patch body 3 can be moved, and due to the attachment relationship between the lower surface of the transdermal patch body 3 and the test peeling plate 2, the movement of the adhesive roller 7 can make the transdermal patch body 3 be peeled off from the surface of the test peeling plate 2.

[0034] The surface of the workbench 1 is fixedly connected with a control panel 10.

[0035] The implementation principle of the transdermal patch in-vitro test processing device in the embodiment of the application is as follows: a person first accurately adheres three different transdermal patch bodies 3 on a test release plate 2, and connects the excess part of the transdermal patch body 3 with the adhesive roller 7, ensures the firm connection, starts the driving motor 902, the output end of the driving motor 902 drives the screw rod 903 to rotate, the screw rod 903 stably rotates under the support of the support shaft seat 905, since the screw rod 903 is threadedly connected with the limiting slide 904, the rotation of the screw rod 903 drives the limiting slide 904 to move linearly along the sliding groove plate 901, the limiting slide 904 is fixedly connected with the pushing frame 6, the linear movement of the limiting slide 904 drives the pushing frame 6 to move linearly, the adhesive roller 7 on the pushing frame 6 moves together with the pushing frame 6, since the transdermal patch body 3 is adhered on the surface of the adhesive roller 7 and the lower surface is adhered on the test release plate 2, the movement of the adhesive roller 7 drives one side of the transdermal patch body 3 to move, so that the transdermal patch body 3 is peeled off from the surface of the test release plate 2, since three test release plates 2 are arranged, when the adhesive roller 7 simultaneously drives three different transdermal patch bodies 3 to peel off, the transdermal patch body 3 with poor adhesion force will first be lifted, the operator can directly observe and compare, when the test requirement is reached or the transdermal patch body 3 is completely peeled off, the driving motor 902 is turned off, the operator records the observed peeling condition of the transdermal patch body 3, such as which transdermal patch is first lifted, and analyzes and evaluates the adhesion force and other performances of the transdermal patch.

[0036] The above embodiment is only a preferred embodiment of the application, and cannot be used to limit the range of protection of the application, and any non-substantial change and replacement made by a person skilled in the art on the basis of the application belongs to the range of protection of the application.

Claims

1. A transdermal patch in-vitro test processing apparatus, characterized by, The utility model provides a test stripping board, it includes workbench (1), the upper surface of workbench (1) is fixedly connected with test stripping board (2), the upper surface of test stripping board (2) is bonded with transdermal patch body (3), the upper surface of workbench (1) is equipped with edge groove (4), the inside of edge groove (4) is slidably connected with extension block (5), the surface of extension block (5) is fixedly connected with push frame (6), the surface of push frame (6) is fixedly connected with adhesive roller (7), the upper surface of workbench (1) is fixedly connected with support frame (8), the surface of support frame (8) is fixedly connected with drive mechanism (9).

2. A transdermal patch in-vitro test processing apparatus as claimed in claim 1, characterized in that: The drive mechanism (9) includes a sliding groove plate (901), the upper surface of the sliding groove plate (901) is fixedly connected with a drive motor (902), the output end of the drive motor (902) is fixedly connected with a lead screw (903), the surface of the lead screw (903) is threadedly connected with a limit sliding carriage (904), and the surface of the lead screw (903) is rotatably connected with a support shaft seat (905).

3. A transdermal patch in-vitro test processing apparatus as claimed in claim 2, characterized in that: The sliding groove plate (901) is fixedly connected to the surface of the support frame (8).

4. A transdermal patch in-vitro test processing apparatus as claimed in claim 2, wherein: The limit sliding carriage (904) is fixedly connected to the surface of the push frame (6) and slidably connected to the inside of the sliding groove plate (901).

5. A transdermal patch in-vitro test processing apparatus as claimed in claim 2, wherein: The support shaft seat (905) is fixedly connected to the upper surface of the sliding groove plate (901).

6. A transdermal patch test treatment device as in claim 1, wherein: The transdermal patch body (3) is bonded to the surface of the adhesive roller (7).

7. A transdermal patch test treatment device as in claim 1, wherein: The surface of the workbench (1) is fixedly connected with a control panel (10).