Magnetic type PCR (Polymerase Chain Reaction) detector

Abstract

The utility model discloses a magnetic type PCR (Polymerase Chain Reaction) detector and belongs to the technical field of biological and medical detection. In the magnetic PCR detector, a base comprises at least one mounting part, each mounting part is provided with a mounting groove, the groove bottom of each mounting groove is provided with a bottom plate, a circuit board assembly and a first magnetic part are arranged below each bottom plate, and a lower plate in a detection assembly is connected with a shell arranged outside a detection module in a sleeving manner in a buckling manner; the second magnetic part and the second circuit assembly are arranged between the detection module and the lower plate, and the second magnetic part is located in the groove of the lower plate. The magnetic poles of the face, away from the detection module, of the second magnetic attraction part are different from the magnetic poles of the face, away from the first circuit board, of the first magnetic attraction part, and therefore when the detection assembly is close to the installation part of the base and the second magnetic attraction part is located above the first magnetic attraction part, the second magnetic attraction part and the first magnetic attraction part attract each other. The effect that the base and the detection assembly in the PCR detector are convenient and fast to disassemble and assemble is achieved.

Description

Technical Field

[0001] This utility model relates to the fields of biology and medical testing technology, and in particular to a magnetic PCR testing instrument. Background Technology

[0002] Polymerase Chain Reaction (PCR) is a biological technique that amplifies DNA fragments by artificially controlling external conditions. A PCR instrument is the core equipment for realizing PCR technology. Its main function is to simulate the DNA replication process in vivo. By precisely controlling temperature changes, it completes the three key steps of DNA denaturation, annealing, and extension, thereby achieving the amplification of a large number of specific DNA fragments.

[0003] The PCR testing instrument in the related technology includes a base and a testing component, which are detachably connected by bolts. The base is used to transmit the test results from the testing component to a computer.

[0004] In the process of realizing this utility model, the inventors found that the related technology has at least the following problems: the bolt-connected base and the detection component are inconvenient to disassemble and assemble, and take a long time. Utility Model Content

[0005] This utility model provides a magnetic PCR detector that solves the problems of inconvenient and time-consuming disassembly and assembly of the base and detection components in related technologies. The technical solution is as follows:

[0006] According to a first aspect of the present invention, a magnetic PCR detector is provided, comprising: a base and at least one detection component;

[0007] The base includes at least one mounting part, each mounting part having a mounting groove, a first circuit assembly and a first magnetic attraction part, the bottom of the mounting groove having a base plate, the first magnetic attraction part being mounted below the base plate, the first circuit assembly including a first circuit board and a first connector, the first circuit board being mounted below the base plate, one end of the first connector being electrically connected to the first circuit board, and the other end passing through the base plate;

[0008] Each of the detection components includes a housing, a detection module, a lower plate, a second magnetic suction part, and a second circuit assembly. The housing is fitted over the detection module and snapped together with the lower plate. The lower plate is located directly below the detection module and has a groove on the side of the lower plate closest to the detection module. The second magnetic suction part is disposed in the groove. The second circuit assembly includes a second circuit board and a second connector. The second circuit board is installed between the lower plate and the detection module and is electrically connected to the detection module. One end of the second connector is connected to the second circuit board, and the other end passes through the lower plate and is electrically connected to the first connector.

[0009] Wherein, the magnetic poles of the side of the second magnetic part away from the detection module are different from those of the side of the first magnetic part away from the first circuit board. When the orthographic projections of the second magnetic part and the first magnetic part overlap and attract each other, the first connector and the second connector are electrically connected.

[0010] Optionally, the first connector includes a plurality of contact copper pillars, and the base plate has a plurality of copper pillar through holes, wherein the plurality of contact copper pillars are located in the plurality of copper pillar through holes;

[0011] The second connector includes multiple contact pins, and the lower plate has multiple pin holes. The multiple contact pins pass through the multiple pin holes. When the orthographic projections of the second magnetic part and the first magnetic part overlap and attract each other, the multiple contact pins are inserted into the multiple copper pillar holes and electrically connected to the multiple contact copper pillars.

[0012] Optionally, the base plate has a raised structure, and the plurality of copper pillar through holes are located on the raised structure;

[0013] The lower plate has a recessed structure, the plurality of pin holes are located in the recessed structure, and the protruding structure can be nested and fitted with the recessed structure.

[0014] Optionally, the protruding structure and the recessed structure have the same shape, and the shape of the protruding structure and the recessed structure is rectangular, trapezoidal, circular, or polygonal; the plurality of copper pillar perforations and the plurality of ejector pin perforations have the same arrangement structure, and the arrangement shape of the plurality of copper pillar perforations and the plurality of ejector pin perforations is single-row, double-row, multi-row, rectangular, trapezoidal, circular, or polygonal.

[0015] Optionally, the first magnetic attraction part includes a first magnet and a second magnet, which are disposed opposite to each other on both sides of the protruding structure on the base plate;

[0016] The second magnetic attraction part includes a third magnet and a fourth magnet, which are disposed opposite to each other on both sides of the recessed structure on the lower plate;

[0017] When the first connector and the second connector are electrically connected, the first magnet is located directly below the third magnet, and the second magnet is located directly below the fourth magnet.

[0018] Optionally, the magnetic poles of the first and second magnets near the detection component are not the same, and the magnetic poles of the third and fourth magnets near the mounting groove are not the same.

[0019] Optionally, the mounting portion further includes two pressure plates and four screws. Each pressure plate has two through holes, and the base plate has four threaded holes. Two of the four screws pass through the two through holes on one pressure plate and are threadedly connected to the two threaded holes on the base plate, thereby locking the first magnet on the side of the base plate away from the detection component. The other two screws pass through the two through holes on the other pressure plate and are threadedly connected to the other two threaded holes on the base plate, thereby locking the second magnet on the side of the base plate away from the detection component.

[0020] Optionally, the base is a rectangular base, and the base includes at least two mounting portions arranged along the extension direction of the long side of the rectangular base.

[0021] Optionally, the detection component has a heat dissipation vent on one side, the base is a circular base, the base includes at least two mounting parts, a guide plate is installed at the center point of the circular base, the at least two mounting parts are evenly arranged around the guide plate, when the orthographic projection of the second magnetic part overlaps with the first magnetic part and they attract each other, the heat dissipation vent of the detection component faces the guide plate.

[0022] The beneficial effects of the technical solution provided by this utility model embodiment include at least the following:

[0023] In the magnetic PCR detector provided by this embodiment, each mounting part has a mounting slot, the bottom of which has a base plate. A circuit board assembly and a first magnetic suction part are disposed below the base plate. The lower plate of the detection assembly is snap-fitted to a housing fitted outside the detection module. A second magnetic suction part and a second circuit assembly are disposed between the detection module and the lower plate, with the second magnetic suction part located in a groove in the lower plate. The magnetic poles of the side of the second magnetic suction part away from the detection module are different from those of the side of the first magnetic suction part away from the first circuit board. Therefore, when the detection assembly is close to the mounting part of the base, and the second magnetic suction part is directly above the first magnetic suction part, the second magnetic suction part and the first magnetic suction part attract each other, allowing for quick installation and connection of the detection assembly and the base. This solves the problem of inconvenient and time-consuming disassembly and assembly of the base and detection assembly in related technologies, achieving the effect of improving the convenience and speed of disassembly and assembly of the base and detection assembly. Attached Figure Description

[0024] To more clearly illustrate the technical solutions in the embodiments of this utility model, the drawings used in the description of the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments of this utility model. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0025] Figure 1 This is a schematic diagram of the structure of a magnetic PCR detector according to an embodiment of the present invention;

[0026] Figure 2 for Figure 1 A cross-sectional view of the detection components of the magnetic PCR detector shown.

[0027] Figure 3 for Figure 1 An exploded view of a portion of the detection component of the magnetic PCR detector shown.

[0028] Figure 4 for Figure 1 An exploded view of the base of the magnetic PCR detector shown.

[0029] Figure 5 for Figure 1 A partial structural diagram of the magnetic PCR detector shown.

[0030] Figure 6 for Figure 1 A partial structural diagram of the magnetic PCR detector shown.

[0031] Figure 7 This is a schematic diagram of another magnetic PCR detector shown in an embodiment of the present invention;

[0032] Figure 8 This is a schematic diagram of another magnetic PCR detector shown in an embodiment of the present invention.

[0033] Explanation of reference numerals in the attached figures:

[0034] 1-Base, 11-Mounting part, 111-Mounting groove, 1111-Base plate, t-Protruding structure, 112-First circuit assembly, 1121-First circuit board, 1122-First connector, z-Contact copper pillar, k-Copper pillar perforation, 113-First magnetic suction part, 1131-First magnet, 1132-Second magnet, 114-Pressure plate, 1141-Through hole, 12-Guide plate;

[0035] 2-Detection component, 21-Housing shell, 22-Detection module, 23-Lower plate, 231-Groove, 232-Recessed structure, 2321-Pin perforation, 24-Second magnetic suction part, 241-Third magnet, 242-Fourth magnet, 25-Second circuit assembly, 251-Second circuit board, 252-Second connector, 2521-Contact pin, 26-Heat dissipation port, 27-Air inlet.

[0036] The accompanying drawings have illustrated specific embodiments of the present invention, which will be described in more detail below. These drawings and descriptions are not intended to limit the scope of the present invention in any way, but rather to illustrate the concept of the present invention to those skilled in the art through reference to specific embodiments. Detailed Implementation

[0037] To make the objectives, technical solutions, and advantages of this utility model clearer, the embodiments of this utility model will be described in further detail below with reference to the accompanying drawings.

[0038] Figure 1 This is a schematic diagram of the structure of a magnetic PCR detector according to an embodiment of the present invention. Figure 2 for Figure 1 The diagram shows a cross-sectional view of the detection components of the magnetic PCR detector. Figure 3 for Figure 1 The image shows an exploded view of a portion of the detection component of a magnetic PCR detector. Figure 4 for Figure 1 The exploded view of the base of the magnetic PCR detector shown; combined with Figure 1 , Figure 2 , Figure 3 and Figure 4 As shown, the magnetic PCR detector may include:

[0039] The base 1 and at least one detection component 2 are included. The base 1 includes at least one mounting part 11. Each mounting part has a mounting groove 111, a first circuit component 112 and a first magnetic part 113. The bottom of the mounting groove 111 has a base plate 1111. The first magnetic part 113 is mounted below the base plate 1111. The first circuit component 112 includes a first circuit board 1121 and a first connector 1122. The first circuit board 1121 is mounted below the base plate 1111. One end of the first connector 1122 is electrically connected to the first circuit board 1121, and the other end passes through the base plate 1111.

[0040] Each detection component 2 includes a housing 21, a detection module 22, a lower plate 23, a second magnetic suction part 24, and a second circuit component 25. The housing 21 is fitted over the detection module 22 and is snapped together with the lower plate 23. The lower plate 23 is located directly below the detection module 22. The side of the lower plate 23 closest to the detection module 22 has a groove 231. The second magnetic suction part 24 is disposed in the groove 231. The second circuit component 25 includes a second circuit board 251 and a second connector 252. The second circuit board 251 is installed between the lower plate 23 and the detection module 22 and is electrically connected to the detection module 22. One end of the second connector 252 is connected to the second circuit board 251, and the other end passes through the lower plate 23 and is electrically connected to the first connector 1122.

[0041] In this configuration, the magnetic poles of the side of the second magnetic part 24 away from the detection module 22 are different from those of the side of the first magnetic part 113 away from the first circuit board 1121. When the orthographic projections of the second magnetic part 24 and the first magnetic part 113 overlap and attract each other, the first connector 1122 and the second connector 252 are electrically connected. The second circuit board 251 transmits the detection information from the detection module 22 to the first connector 1122 through the second connector 252. The first circuit board 1121 then transmits the detection information obtained from the first connector 1122 to the connection terminal outside the base, thus completing the acquisition of PCR detection information.

[0042] In summary, the magnetic PCR detector provided by this embodiment of the invention has a mounting slot in each mounting part, with a base plate at the bottom of the mounting slot. A circuit board assembly and a first magnetic suction part are disposed below the base plate. The lower plate of the detection assembly is snap-fitted to the housing fitted outside the detection module. A second magnetic suction part and a second circuit assembly are disposed between the detection module and the lower plate, with the second magnetic suction part located in a groove in the lower plate. The magnetic poles of the side of the second magnetic suction part away from the detection module are different from those of the side of the first magnetic suction part away from the first circuit board. Therefore, when the detection assembly approaches the mounting part of the base, and the second magnetic suction part is above the first magnetic suction part, the second magnetic suction part and the first magnetic suction part attract each other, allowing for quick installation and connection of the detection assembly and the base. This achieves the effect of improving the ease and speed of assembling and disassembling the base and detection assembly in the PCR detector.

[0043] Optionally, such as Figure 4 As shown, the first connector 1122 includes multiple contact copper pillars z, and the base plate has multiple copper pillar through holes ( Figure 4 (Not shown), multiple contact copper pillars z are located in multiple copper pillar through holes.

[0044] like Figure 3 As shown, the second connector 252 includes multiple contact pins 2521, and the lower plate 23 has multiple pin through holes. Figure 3 (Not shown), multiple contact pins 2521 pass through multiple pin holes. For example... Figure 2As shown, when the orthographic projections of the second magnetic suction part 24 and the first magnetic suction part 113 overlap and attract each other, multiple contact pins are inserted into the holes of multiple copper pillars and electrically connected to the multiple contact copper pillars. At this time, the detection component and the base are installed and connected. During detection, the data information detected by the detection module can be transmitted to the multiple contact copper pillars through the multiple contact pins, that is, the detection data of the detection component is transmitted to the base.

[0045] Figure 5 for Figure 2 The diagram shows a partial structural diagram of a magnetic PCR detector. Figure 5 The diagram shown is a three-dimensional structural schematic of the base, combined with... Figure 4 and Figure 5 As shown, the base plate 1111 has a raised structure t, and multiple copper pillar through holes k are located on the raised structure t.

[0046] Figure 6 for Figure 2 The diagram shows a partial structural diagram of a magnetic PCR detector. Figure 6 The diagram shown is a three-dimensional structural schematic of the detection component, combined with... Figure 3 and Figure 6 As shown, the lower plate 23 has a recessed structure 232, and multiple pin holes 2321 are located in the recessed structure 232. When the detection component and the base are installed, the protruding structure and the recessed structure are nested together. During the assembly process of the detection component and the base, the setting of the protruding structure and the recessed structure can further refine the positioning, thereby making the assembly of the detection component and the base more convenient and improving the assembly speed.

[0047] Optionally, the protruding structure and the recessed structure have the same shape, and the shape of the protruding structure and the recessed structure can be rectangular, trapezoidal, circular, or polygonal, wherein, Figure 3 and Figure 6 The diagram shows the case where the protruding and recessed structures are trapezoidal in shape. However, the protruding and recessed structures can also be other shapes, and this embodiment of the present invention is not limited to any particular shape.

[0048] Optionally, the multiple copper pillar perforations and the multiple ejector pin perforations are arranged in the same way, and the arrangement shape of the multiple copper pillar perforations and the multiple ejector pin perforations can be a single row, double row, multiple rows, rectangular arrangement, trapezoidal arrangement, circular arrangement, or polygonal arrangement, wherein, Figure 3 and Figure 6The diagram shows a configuration where multiple copper pillar perforations and multiple ejector pin perforations are arranged in a double row. These perforations can also be arranged in other ways, and this embodiment is not limited to these arrangements. When the detection component is assembled with the base, the detection component and base can be assembled when the waistline on the trapezoidal protrusion is parallel to the waistline on the trapezoidal recess. However, when the waistline on the trapezoidal protrusion intersects with the waistline on the trapezoidal recess, the detection component and base cannot be assembled, and the orientation of the detection component needs to be reversed. The trapezoidal shape serves as a foolproof design, preventing the detection component from being installed backwards, thus achieving precise positioning and rapid assembly of the detection component and base.

[0049] Combination Figure 2 , Figure 3 , Figure 4 As shown, the first magnetic attraction part 113 includes a first magnet 1131 and a second magnet 1132, which are disposed opposite to each other on the protruding structure on the base plate 1111. Figure 2 , Figure 3 , Figure 4 (Not shown) on both sides. The second magnetic attraction part 24 includes a third magnet 241 and a fourth magnet 242, which are disposed opposite to each other on the lower plate 23 in the recessed structure ( Figure 2 , Figure 3 , Figure 4 (Not shown) on both sides. When the first connector 1122 and the second connector 252 are electrically connected, the first magnet 1131 is located directly below the third magnet 241, and the second magnet 1132 is located directly below the fourth magnet 242.

[0050] Optionally, the magnetic poles of the first and second magnets near the detection component are not aligned, and the magnetic poles of the third and fourth magnets near the mounting groove are not aligned. For example, the N pole of the first magnet faces upwards, the S pole of the second magnet faces upwards, the S pole of the third magnet faces downwards, and the N pole of the fourth magnet faces downwards. When the detection component is assembled with the base, if the fourth magnet is directly above the first magnet, since the fourth and first magnets have the same magnetic poles, they cannot be attracted. This indicates that the detection component is facing the wrong direction and needs to be reversed so that the third magnet is directly above the first magnet. In other words, the distribution of the four magnets in this invention has a foolproof function, preventing the base and detection component from being installed in the wrong direction. The magnetic poles of the four magnets can also be arranged in other ways, and this embodiment of the invention is not limited to these methods.

[0051] like Figure 4 As shown, the mounting section also includes two pressure plates 114 and four screws. Figure 4(Not shown) Each pressure plate 114 has two through holes 1141, and the base plate 1111 has four threaded holes. Two of the four screws pass through the two through holes 1141 on one pressure plate 114 and are threadedly connected to the two threaded holes on the base plate 1111, pressing and locking the first magnet 1131 onto the side of the base plate 1111 away from the detection component. The other two screws pass through the two through holes on another pressure plate and are threadedly connected to the other two threaded holes on the base plate, pressing and locking the second magnet 1132 onto the side of the base plate 1111 away from the detection component. Since the first magnet 1131 and the second magnet 1132 are located below the base plate, the magnets are fixed by bolts connecting the pressure plate and the base plate, which can improve the stability of the magnets and prevent the magnets from shifting during the handling of the base plate, thus avoiding unsuccessful assembly of the detection component and the base due to magnet shifting.

[0052] Figure 7 This is a schematic diagram of another magnetic PCR detector according to an embodiment of the present invention, as shown below. Figure 7 As shown, the base 1 is a rectangular base, and the base 1 includes at least two mounting parts 11, which are arranged along the extension direction of the long side of the rectangular base. Each mounting part is equipped with a detection component 2. Figure 7 The diagram shows a case where there are 4 mounting parts and 4 detection components. The number of mounting parts can also be 3, 5, 6, etc. This embodiment of the utility model does not limit the number of mounting parts. Since the detection components and mounting parts can be quickly magnetically attached, the number of detection components can be flexibly increased or decreased. The disassembly and assembly of the detection components do not affect the operation of other detection components located on the mounting parts.

[0053] Figure 8 This is a schematic diagram of another magnetic PCR detector according to an embodiment of the present invention, as shown below. Figure 8 As shown, the detection component 2 has a heat dissipation port 26 on one side and an air inlet 27 on the other side. The base 1 is a circular base, which includes at least two mounting parts 11. A guide plate 12 is installed at the center point of the circular base. The at least two mounting parts 11 are evenly arranged around the guide plate 12. When the orthographic projections of the second magnetic part and the first magnetic part overlap and attract each other, the heat dissipation port 26 of the detection component 2 faces the guide plate 12. Figure 8 The illustration shows a case where there are 8 mounting parts and 8 detection components. The number of mounting parts can also be 3, 4, 5, 6, etc. The present invention does not limit this. Since the detection components and mounting parts can be quickly magnetically attached, the number of detection components can be flexibly increased or decreased. The disassembly and assembly of the above-mentioned detection components does not affect the operation of other detection components located on the mounting parts.

[0054] In this invention, the terms "first," "second," "third," and "fourth" are used for descriptive purposes only and should not be construed as indicating or implying relative importance. The term "multiple" refers to two or more unless otherwise expressly defined.

[0055] The above description is only a preferred embodiment of the present utility model and is not intended to limit the present utility model. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present utility model should be included within the protection scope of the present utility model.

Claims

1. A magnetic PCR detector, characterized in that, include: Base and at least one detection component; The base includes at least one mounting part, each mounting part having a mounting groove, a first circuit assembly and a first magnetic attraction part, the bottom of the mounting groove having a base plate, the first magnetic attraction part being mounted below the base plate, the first circuit assembly including a first circuit board and a first connector, the first circuit board being mounted below the base plate, one end of the first connector being electrically connected to the first circuit board, and the other end passing through the base plate; Each of the detection components includes a housing, a detection module, a lower plate, a second magnetic suction part, and a second circuit assembly. The housing is fitted over the detection module and snapped together with the lower plate. The lower plate is located directly below the detection module and has a groove on the side of the lower plate closest to the detection module. The second magnetic suction part is disposed in the groove. The second circuit assembly includes a second circuit board and a second connector. The second circuit board is installed between the lower plate and the detection module and is electrically connected to the detection module. One end of the second connector is connected to the second circuit board, and the other end passes through the lower plate and is electrically connected to the first connector. Wherein, the magnetic poles of the side of the second magnetic part away from the detection module are different from those of the side of the first magnetic part away from the first circuit board. When the orthographic projections of the second magnetic part and the first magnetic part overlap and attract each other, the first connector and the second connector are electrically connected.

2. The magnetic PCR detector according to claim 1, characterized in that, The first connector includes multiple contact copper pillars, and the base plate has multiple copper pillar through holes, with the multiple contact copper pillars located in the multiple copper pillar through holes; The second connector includes multiple contact pins, and the lower plate has multiple pin holes. The multiple contact pins pass through the multiple pin holes. When the orthographic projections of the second magnetic part and the first magnetic part overlap and attract each other, the multiple contact pins are inserted into the multiple copper pillar holes and electrically connected to the multiple contact copper pillars.

3. The magnetic PCR detector according to claim 2, characterized in that, The base plate has a raised structure, and the plurality of copper pillar through holes are located on the raised structure; The lower plate has a recessed structure, the plurality of pin holes are located in the recessed structure, and the protruding structure can be nested and fitted with the recessed structure.

4. The magnetic PCR detector according to claim 3, characterized in that, The protruding and recessed structures have the same shape, and the protruding and recessed structures are rectangular, trapezoidal, circular, or polygonal in shape; the multiple copper pillar perforations and the multiple ejector pin perforations are arranged in the same way, and the arrangement of the multiple copper pillar perforations and the multiple ejector pin perforations is single-row, double-row, multi-row, rectangular, trapezoidal, circular, or polygonal.

5. The magnetic PCR detector according to claim 3, characterized in that, The first magnetic attraction part includes a first magnet and a second magnet, which are disposed opposite to each other on both sides of the protruding structure on the base plate; The second magnetic attraction part includes a third magnet and a fourth magnet, which are disposed opposite to each other on both sides of the recessed structure on the lower plate; When the first connector and the second connector are electrically connected, the first magnet is located directly below the third magnet, and the second magnet is located directly below the fourth magnet.

6. The magnetic PCR detector according to claim 5, characterized in that, The magnetic poles of the first and second magnets near the detection component are not the same, and the magnetic poles of the third and fourth magnets near the mounting groove are not the same.

7. The magnetic PCR detector according to claim 5, characterized in that, The mounting section also includes two pressure plates and four screws. Each pressure plate has two through holes, and the base plate has four threaded holes. Two of the four screws pass through the two through holes on one pressure plate and are threadedly connected to the two threaded holes on the base plate, thereby locking the first magnet on the side of the base plate away from the detection component. The other two screws pass through the two through holes on the other pressure plate and are threadedly connected to the other two threaded holes on the base plate, thereby locking the second magnet on the side of the base plate away from the detection component. 8.The magnetic PCR detector according to claim 1, characterized in that, The base is a rectangular base, and the base includes at least two mounting parts, which are arranged along the extension direction of the long side of the rectangular base.

9. The magnetic PCR detector according to claim 1, characterized in that, The detection component has a heat dissipation vent on one side, and the base is a circular base. The base includes at least two mounting parts, and a guide plate is installed at the center point of the circular base. The at least two mounting parts are evenly arranged around the guide plate. When the orthogonal projections of the second magnetic part and the first magnetic part overlap and attract each other, the heat dissipation vent of the detection component faces the guide plate.

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