Centrifugal device for extracting heparin sodium
By introducing a refrigeration chamber, a pull-out ice box, and a magnetic positioning mechanism into the centrifuge, the problem of unstable temperature during the extraction of heparin sodium was solved, thus protecting the activity of heparin sodium and improving the extraction efficiency.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- SHUNYIKANG (HEBEI) BIOTECHNOLOGY CO LTD
- Filing Date
- 2025-04-25
- Publication Date
- 2026-04-24
AI Technical Summary
Existing centrifuges lack refrigeration capabilities during heparin sodium extraction, leading to reduced heparin sodium activity.
A centrifuge device with a refrigeration chamber was designed. The refrigeration chamber is equipped with a pull-out ice box and a magnetic positioning mechanism. Combined with a temperature sensor and a display screen, it ensures temperature uniformity and stability. A baffle is set in the centrifuge chamber to promote airflow.
It effectively maintains the activity of heparin sodium, avoids excessively high or low temperatures, ensures temperature uniformity and stability during the extraction process, reduces costs, and facilitates the disassembly and installation of the ice box.
Smart Images

Figure CN224157023U_ABST
Abstract
Description
Technical Field
[0001] This utility model relates to the technical field of heparin sodium extraction, specifically a centrifuge device for heparin sodium extraction. Background Technology
[0002] Heparin sodium is a mucopolysaccharide sulfate anticoagulant. Currently, heparin is the most effective and clinically used anticoagulant drug in the world, primarily used for cardiovascular and cerebrovascular diseases and hemodialysis treatment. In hemodialysis, it is the only effective specific drug. Clinical applications and research show that in addition to its anticoagulant effect, heparin also possesses various other biological activities and clinical uses, including lipid-lowering effects, anti-smooth muscle cell (SMC) proliferation, and fibrinolysis promotion. Centrifugation is a crucial step in the extraction of heparin sodium, mainly used for separating and purifying heparin; however, most existing centrifuges lack refrigeration capabilities, which reduces the activity of heparin sodium. Utility Model Content
[0003] To address the shortcomings of existing technologies, this invention provides a centrifuge device for extracting heparin sodium.
[0004] To solve the above-mentioned technical problems, this utility model provides the following technical solution:
[0005] This utility model discloses a centrifugal device for extracting heparin sodium, comprising a centrifuge body, a centrifuge chamber, a vertically arranged rotating shaft inside the centrifuge chamber, a centrifuge rack installed at the end of the rotating shaft, and positioning holes for positioning centrifuge containers on the centrifuge rack; a cover plate is fitted onto the centrifuge body; a refrigeration chamber is provided at the bottom of the centrifuge chamber, and multiple ventilation holes are provided on the side wall between the refrigeration chamber and the centrifuge chamber; a pull-out ice box is installed in the refrigeration chamber, and ice packs are provided inside the ice box; the ice box is fixed to the refrigeration chamber by a magnetic positioning mechanism; and a baffle is provided below the centrifuge rack on the rotating shaft.
[0006] As a preferred embodiment of this utility model, the centrifuge body is provided with a temperature sensor inside the centrifuge chamber for detecting the internal temperature of the centrifuge chamber, and the outer wall of the centrifuge body is also provided with a display screen for connecting to the temperature sensor and for displaying the temperature value detected by the temperature sensor.
[0007] As a preferred embodiment of this utility model, both the inner wall of the centrifuge chamber and the inner wall of the ice box are provided with heat-insulating linings.
[0008] As a preferred embodiment of this utility model, the magnetic positioning mechanism includes an iron sheet disposed at the inner end of the ice box, and an electromagnet corresponding to the position of the iron sheet is provided on the outer wall of the refrigeration cavity.
[0009] As a preferred embodiment of the present invention, the outer end of the ice box is provided with an end cap, and the end cap is provided with a sealing layer for sealing the connection between the end cap and the refrigeration cavity.
[0010] As a preferred embodiment of this utility model, the refrigeration cavity is semi-circular, and the shape of the ice box is adapted to the refrigeration cavity.
[0011] The beneficial effects of this utility model are:
[0012] 1. This centrifuge for extracting heparin sodium has a refrigeration chamber at the bottom of the centrifuge cavity and is equipped with a pull-out ice box. Refrigeration is achieved using ice packs as the cold source, which is low-cost and ensures a consistent temperature that is neither too low nor too high, thus not affecting the activity of heparin sodium. The ice box is fixed to the refrigeration chamber by a magnetic positioning mechanism, which facilitates easy positioning, good performance, and convenient disassembly. The rotating shaft has a baffle plate located below the centrifuge frame. The baffle plate rotates with the rotating shaft, thereby creating airflow around the centrifuge cavity and ensuring uniform temperature distribution.
[0013] 2. This centrifuge for extracting sodium heparin has heat-insulating liners on both the inner wall of the centrifuge chamber and the inner wall of the ice box, thus providing heat insulation. Furthermore, in this invention, the magnetic positioning mechanism includes an iron plate located at the inner end of the ice box, and an electromagnet corresponding to the position of the iron plate is located on the outer wall of the refrigeration chamber. When the electromagnet is energized, it generates magnetism, attracting the iron plate at the inner end of the ice box, thus providing a good fixing effect. When disassembling the ice box, the electromagnet is de-energized, allowing it to re-engage with the ice box and facilitating disassembly. Attached Figure Description
[0014] The accompanying drawings are provided to further illustrate the present invention and form part of the specification. They are used together with the embodiments of the present invention to explain the present invention, but do not constitute a limitation thereof. In the drawings:
[0015] Figure 1 This is a schematic diagram of the structure of a centrifuge device for extracting heparin sodium according to this utility model;
[0016] Figure 2 This is a schematic diagram of the internal structure of the centrifuge body of a centrifuge device for extracting heparin sodium according to this utility model;
[0017] Figure 3 This is a schematic diagram of the cavity structure of a centrifuge device for extracting heparin sodium according to this utility model;
[0018] Figure 4This is a schematic diagram of the ice box structure of a centrifugal device for extracting heparin sodium according to this utility model.
[0019] In the diagram: 1. Centrifuge body; 2. Centrifuge chamber; 3. Rotating shaft; 4. Centrifuge rack; 5. Positioning hole; 6. Refrigeration chamber; 7. Ventilation hole; 8. Ice box; 9. Ice pack; 10. Baffle plate; 11. Temperature sensor; 13. Insulation liner; 14. Iron sheet; 15. Electromagnet; 16. Display screen; 17. End cap; 18. Sealing layer; 19. Cover plate; 20. Insertion chamber. Detailed Implementation
[0020] The preferred embodiments of the present invention will be described below with reference to the accompanying drawings. It should be understood that the preferred embodiments described herein are for illustration and explanation only and are not intended to limit the present invention.
[0021] Example: Figure 1 , Figure 2 , Figure 3 and Figure 4 As shown, this utility model discloses a centrifugal device for extracting heparin sodium, comprising a centrifuge body 1, a centrifuge chamber 2 on the centrifuge body, a vertically arranged rotating shaft 3 inside the centrifuge chamber 2, and a centrifuge frame 4 installed at the end of the rotating shaft 3, and a positioning hole 5 for positioning the centrifuge container on the centrifuge frame 4; a cover plate 19 is covered on the centrifuge body 1; a refrigeration chamber 6 is provided at the bottom of the centrifuge chamber 2 on the centrifuge body 1, and a plurality of ventilation holes 7 are provided on the side wall between the refrigeration chamber 6 and the centrifuge chamber 2; a pull-out ice box 8 is installed in the refrigeration chamber 6, and an ice pack 9 is provided inside the ice box 8; the ice box 8 is fixed to the refrigeration chamber 6 by a magnetic positioning mechanism; and a baffle plate 10 is provided below the centrifuge frame 4 on the rotating shaft. A refrigeration chamber 6 is provided at the bottom of the centrifuge chamber 2, and a pull-out ice box 8 is provided. The ice box 9 is used as the cold source for refrigeration, which is low-cost and maintains a constant temperature that is neither too low nor too high, thus not affecting the activity of heparin sodium. The ice box 8 is fixed to the refrigeration chamber 6 by a magnetic positioning mechanism, which is easy to position, has good effect, and is easy to disassemble. The rotating shaft is provided with a baffle 10 below the centrifuge frame 4. The baffle rotates with the rotating shaft 3, so that the air in the centrifuge chamber 2 is circulated, thus ensuring uniform temperature distribution.
[0022] The centrifuge body 1 is equipped with a temperature sensor 11 inside the centrifuge chamber 2 for detecting the internal temperature of the centrifuge chamber 2. The outer wall of the centrifuge body 1 is also equipped with a display screen 16 for connecting to the temperature sensor 11 and for displaying the temperature value detected by the temperature sensor. This facilitates the detection of the internal temperature and makes it convenient to replace the ice pack in the ice box in a timely manner.
[0023] The inner walls of the centrifuge chamber 2 and the ice box 8 are both provided with heat-insulating linings 13, which serve to insulate and keep the temperature.
[0024] The magnetic positioning mechanism includes an iron plate 14 disposed at the inner end of the ice box 8, and an electromagnet 15 corresponding to the position of the iron plate is provided on the outer wall of the refrigeration cavity 6. The electromagnet is energized to generate magnetism, which attracts the iron plate at the inner end of the ice box, thus providing a good fixing effect. When the ice box is disassembled, the electromagnet is de-energized, so that the electromagnet can contact the adsorption effect on the ice box, thereby facilitating disassembly.
[0025] The ice box 8 has an end cap 17 at its outer end, and the end cap 17 has a sealing layer 18 that seals the connection between the end cap 17 and the refrigeration chamber 6. This gives the connection between the ice box 8 and the refrigeration chamber 6 a good sealing effect and reduces energy loss.
[0026] The refrigeration chamber 6 is semi-circular, and the shape of the ice box 8 is adapted to the refrigeration chamber 6 to avoid the rotation axis. The refrigeration chamber 6 is provided with an insertion cavity for the ice box 8 to be inserted, and the front end of the ice box 8 is provided with a guide part with a size smaller than the end of the ice box 8, so that the ice box 8 can be easily inserted into the refrigeration chamber 6.
[0027] During operation, this centrifuge for heparin sodium extraction has a refrigeration chamber 6 at the bottom of the centrifuge chamber 2, and a pull-out ice box 8. Refrigeration is achieved using ice packs 9 as the cold source, resulting in low cost and a consistent temperature that is neither too low nor too high, thus preventing any impact on the activity of the heparin sodium. The ice box 8 is magnetically fixed to the refrigeration chamber 6, providing easy positioning, good performance, and convenient disassembly. A baffle 10 is located below the centrifuge frame 4 on the rotating shaft 3. The baffle rotates with the rotating shaft 3, causing airflow within the centrifuge chamber 2, thus ensuring uniform temperature distribution.
[0028] Finally, it should be noted that the above description is merely a preferred embodiment of this utility model and is not intended to limit the utility model. Although the utility model has been described in detail with reference to the foregoing embodiments, those skilled in the art can still modify the technical solutions described in the foregoing embodiments or make equivalent substitutions for some of the technical features. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of this utility model should be included within the protection scope of this utility model.
Claims
1. A centrifugal apparatus for extracting heparin sodium, comprising a centrifuge body (1), a centrifuge chamber (2) provided on the centrifuge body, a vertically arranged rotating shaft (3) provided in the centrifuge chamber (2), and a centrifuge rack (4) installed at the end of the rotating shaft (3), and a positioning hole (5) provided on the centrifuge rack (4) for positioning the centrifuge container; a cover plate (19) is provided on the centrifuge body (1); characterized in that, The centrifuge body (1) has a refrigeration chamber (6) at the bottom of the centrifuge chamber (2). The side wall between the refrigeration chamber (6) and the centrifuge chamber (2) has multiple ventilation holes (7). The refrigeration chamber (6) is equipped with a pull-out ice box (8), and the ice box (8) contains an ice pack (9). The ice box (8) and the refrigeration chamber (6) are fixed together by a magnetic positioning mechanism. The rotating shaft (3) has a baffle plate (10) located below the centrifuge rack (4).
2. The centrifugal device for extracting heparin sodium according to claim 1, characterized in that, The centrifuge body (1) is provided with a temperature sensor (11) inside the centrifuge chamber (2) for detecting the internal temperature of the centrifuge chamber (2). The outer wall of the centrifuge body (1) is also provided with a display screen (16) for connecting to the temperature sensor (11) and for displaying the temperature value detected by the temperature sensor.
3. The centrifugal device for extracting heparin sodium according to claim 1, characterized in that, The inner wall of the centrifuge chamber (2) and the inner wall of the ice box (8) are both provided with heat-insulating linings (13).
4. The centrifugal device for extracting heparin sodium according to claim 2, characterized in that, The magnetic positioning mechanism includes an iron plate (14) disposed at the inner end of the ice box (8), and an electromagnet (15) corresponding to the position of the iron plate is provided on the outer wall of the refrigeration cavity (6).
5. The centrifugal device for extracting heparin sodium according to claim 1, characterized in that, The ice box (8) has an end cap (17) at its outer end, and the end cap (17) has a sealing layer (18) for sealing the connection between the end cap (17) and the refrigeration chamber (6).
6. A centrifuge apparatus for extracting heparin sodium according to claim 5, characterized in that, The refrigeration chamber (6) is semi-circular, and the shape of the ice box is adapted to the refrigeration chamber (6).