Flow channel system of thin-film type micro-fluidic chip

Abstract

The utility model belongs to the technical field of accessories of biological sample detection equipment, and particularly relates to a flow channel system of a thin-film micro-fluidic chip. The utility model provides a flow channel system of a thin-film type micro-fluidic chip, and aims to solve the problem that a flow channel of a thin-film type micro-fluidic chip in the prior art cannot be completely disconnected. The utility model relates to a flow channel system of a thin-film micro-fluidic chip. The flow channel system comprises a chip body with a flow channel and a control assembly for controlling the on-off of the flow channel, the control assembly comprises a base and further comprises a pressing head used for pressing one part, corresponding to the flow channel, of the chip body into the control groove, the chip body is located between the base and the pressing head, and the flow channel stretches across the control groove. When the flow channel needs to be disconnected, the pressing head presses downwards to enable a part of the chip body forming the flow channel to enter the groove, and the part of the chip body is located between the pressing head and the inner wall of the control groove, so that the chip body is bent, the flow channel is further bent, and the flow channel can be completely disconnected.

Description

Technical Field

[0001] This utility model belongs to the technical field of biological sample detection equipment accessories, specifically relating to a flow channel system of a thin-film microfluidic chip. Background Technology

[0002] In recent years, based on continuous innovation in the field of lab-on-a-chip research, the chips currently on the market mainly have the following shortcomings: Most chip detection adopts mechanical driving principles such as pneumatic micropumps, piezoelectric micropumps, and reciprocating micropumps, or non-mechanical driving principles such as electroosmotic driving and gravity driving, which are complex and have high requirements; Chips mostly use capillary action to control fluids, controlling the fluid system through the surface tension, power consumption, and flow resistance of the fluid, but this cannot meet the requirements of PCR reaction for airtightness; or they use multilayer materials plus thin films, controlling the gas in the thin film channel to deform the film and thus block the liquid flow channel, achieving active control of the liquid path, but the chip manufacturing process is difficult and the control system is complex.

[0003] In other words, the flow channel on / off control of existing microfluidic chips is very inconvenient, resulting in the flow channel not being able to be completely disconnected. Utility Model Content

[0004] This invention provides a flow channel system for a thin-film microfluidic chip, aiming to solve the problem that the flow channels of thin-film microfluidic chips cannot be completely disconnected in the prior art.

[0005] To solve the above-mentioned technical problems, the technical solution adopted by this utility model is as follows:

[0006] A flow channel system for a thin-film microfluidic chip includes a chip body having flow channels and a control component for controlling the on / off state of the flow channels;

[0007] The control component includes a base with a control slot. The control component also includes a pressure head for pressing a portion of the chip body corresponding to a flow channel into the control slot. The chip body is located between the base and the pressure head, and the channel spans the control slot.

[0008] A further improved solution: the cross-sectional shape of the control groove is V-shaped, and the cross-sectional shape of the pressure head is V-shaped; or, the cross-sectional shape of the control groove is U-shaped, and the cross-sectional shape of the pressure head is U-shaped.

[0009] Based on the above technical solution: the cross-sectional shape of the control groove is V-shaped or U-shaped, the cross-sectional shape of the pressure head is V-shaped or U-shaped, and a part of the flow channel formed on the chip body is pressed into the control groove by the pressure head and forms a V-shaped or U-shaped shape, that is, the chip body is bent into a V-shaped or U-shaped shape, thereby effectively closing the flow channel and completely disconnecting the flow channel.

[0010] A further improved solution: the cross-sectional shape of the control groove is rectangular, and the cross-sectional shape of the pressure head is rectangular.

[0011] Based on the above technical solution: the cross-sectional shape of the control groove is rectangular, the cross-sectional shape of the pressure head is rectangular, after a part of the flow channel formed on the chip body is pressed into the control groove, at least three or four folds will be formed on the chip body. After the chip body is bent multiple times, the flow channel can be disconnected more effectively, so that the flow channel can be completely disconnected and leakage at the disconnection point of the flow channel can be prevented.

[0012] A further improved solution: There are at least two control slots, and at least two control slots are arranged along the length of the flow channel, with each control slot corresponding to a pressure head.

[0013] Based on the above technical solution: there are at least two control grooves, and at least two control grooves are arranged along the length of the flow channel. The same flow channel is disconnected by multiple control grooves and pressure heads, so that the flow channel has better disconnection performance and the flow channel disconnection point is not easy to leak liquid.

[0014] A further improvement: The pressure head is provided with a rounded corner to prevent the pressure head from damaging the chip body.

[0015] Based on the above technical solution: the grounding head is provided with an arc corner to prevent the grounding head from damaging the chip body, and the pressure head is not easy to scratch the chip body, so that the chip body is not easily damaged.

[0016] A further improvement: The control groove is provided with a rounded corner to make the inner wall of the control groove transition smoothly.

[0017] Based on the above technical solution: the control slot is provided with a rounded corner that makes the inner wall of the control slot transition smoothly, so that the inner wall of the control slot is not easy to scratch the chip body and the chip body is not easy to be damaged.

[0018] A further improvement: The control component further includes a driver that drives the pressure head to move up and down relative to the base.

[0019] Based on the above technical solution: the control component also includes a driver that drives the pressure head to move up and down relative to the base, making the pressure head easy to control.

[0020] A further improved solution: The driver is an electromagnet, the electromagnet includes an armature that drives the pressure head, and the pressure head is fixed to the armature by screws.

[0021] Based on the above technical solution: the driver is an electromagnet, which has a simple structure and is easy to maintain.

[0022] A further improved solution: The chip body includes a first film layer and a second film layer, and the flow channel is located between the first film layer and the second film layer.

[0023] Based on the above technical solution: the chip body includes a first film layer and a second film layer, and the flow channel is formed by a part of the first film layer and a part of the second film layer. The chip body is easy to deform and can better contact the inner wall of the control groove, thereby making the flow channel have a better disconnection effect.

[0024] A further improved solution: A heat-sealing region forming the flow channel is provided between the first film layer and the second film layer.

[0025] Based on the above technical solution: a heat-sealing area is provided between the first film layer and the second film layer to form the flow channel. By providing the heat-sealing area, the flow channel has better stability and other parts of the flow channel are less prone to leakage.

[0026] The beneficial effects of this utility model are as follows:

[0027] This invention features a base with a control groove on it and a pressure head above the base. The chip body is located between the base and the pressure head. When the flow channel needs to be disconnected, the pressure head presses down, forcing a portion of the chip body into the control groove. Since the flow channel spans the control groove, the pressure head presses down, causing a portion of the chip body forming the flow channel to enter the groove. This portion of the chip body is located between the pressure head and the inner wall of the control groove, thus bending the chip body and consequently bending the flow channel, allowing it to be completely disconnected. Liquid cannot pass through the area of ​​the flow channel squeezed by the pressure head. Attached Figure Description

[0028] To more clearly illustrate the technical solutions of the embodiments of this utility model, the accompanying drawings used in the embodiments will be briefly introduced below. It should be understood that the following drawings only show some embodiments of this utility model and should not be regarded as a limitation on the scope. For users of ordinary skills in the art, other related drawings can be obtained from these drawings without creative effort.

[0029] Figure 1 This is a front view of the flow channel system of a thin-film microfluidic chip according to this utility model.

[0030] Figure 2 This is a front view of the base in the flow channel system of a thin-film microfluidic chip according to this utility model.

[0031] Figure 3 This is a front view of the control groove in the flow channel system of a thin-film microfluidic chip according to this utility model, when the cross-sectional shape is rectangular.

[0032] Figure 4This is a schematic diagram of the chip body in the flow channel system of a thin-film microfluidic chip according to this utility model.

[0033] Explanation of the labels in the diagram:

[0034] 1-Chip body; 11-Flow channel; 2-Control component; 21-Base; 211-Control slot; 22-Pressure head; 221-Driver. Detailed Implementation

[0035] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. It should be understood that the specific embodiments described herein are merely for explaining the present utility model and are not intended to limit the present utility model. All other embodiments obtained by users of the art based on the embodiments of the present utility model without creative effort are within the protection scope of the present utility model.

[0036] refer to Figures 1 to 4 A flow channel 11 system for a thin-film microfluidic chip includes a chip body 1 having a flow channel 11 and a control component 2 for controlling the on / off state of the flow channel 11.

[0037] The control component 2 includes a base 21, on which a control groove 211 is provided. The control component 2 also includes a pressure head 22 for pressing a portion of the flow channel of the chip body 1 into the control groove 211. The chip body 1 is located between the base 21 and the pressure head 22, and the channel spans the control groove 211.

[0038] Complete disconnection of flow channel 11 means that flow channel 11 is closed, and liquid entering flow channel 11 from one end cannot be discharged from the other end of flow channel 11.

[0039] refer to Figures 1 to 2 Wherein: the cross-sectional shape of the control groove 211 is V-shaped, and the cross-sectional shape of the pressure head 22 is V-shaped. Alternatively, the cross-sectional shape of the control groove 211 is U-shaped, and the cross-sectional shape of the pressure head 22 is U-shaped.

[0040] refer to Figure 3 Alternatively: the cross-sectional shape of the control groove 211 is rectangular, and the cross-sectional shape of the pressure head 22 is rectangular.

[0041] The more times the chip body 1 is bent, the more times the part of the chip body 1 that forms the flow channel 11 is bent, the more times the flow channel 11 is bent, the more contact parts the two side walls of the flow channel 11 have, which makes the flow channel 11 have a better disconnection effect, and the liquid is less likely to leak at the disconnection point of the flow channel 11.

[0042] Wherein: there are at least two control grooves 211, and at least two control grooves 211 are arranged along the length direction of the flow channel 11, and the control grooves 211 correspond one-to-one with the pressure head 22.

[0043] When the flow channel 11 is relatively long, or when there is no limitation on the volume of the chip body 1 and the volume of the control component 2, multiple control slots 211 can be set so that the same flow channel 11 can be controlled by multiple control slots 211 to open and close. In actual use, even if some control slots 211 cannot cooperate with the pressure head 22 to disconnect the flow channel 11, it will not affect other control slots 211 to cooperate with other pressure heads 22 to disconnect the flow channel 11, so that the flow channel 11 system has higher stability.

[0044] Wherein: the pressure head 22 is provided with an arc corner to prevent the pressure head 22 from damaging the chip body 1.

[0045] The control groove 211 is provided with a rounded corner to make the inner wall of the control groove 211 transition smoothly.

[0046] The rounded corners set in the control groove 211 make the inner wall of the control groove 211 transition smoothly, and the rounded corners set on the pressure head 22 make the outer wall of the pressure head 22 transition smoothly, so that there are no sharp edges on the pressure head 22 and in the control groove 211, and the chip body 1 is not easily damaged.

[0047] refer to Figure 1 , Figure 3 The control component 2 further includes a driver 221 that drives the pressure head 22 to move up and down relative to the base 21.

[0048] The actuator 221 is an electromagnet, which includes an armature that drives the pressure head 22, and the pressure head 22 is fixed to the armature by screws. The electromagnet also includes a coil, the position of which is fixed, while the armature moves relative to the coil.

[0049] The actuator 221 can also be replaced by a cylinder or the like.

[0050] Wherein: the chip body 1 includes a first film layer and a second film layer, and the flow channel 11 is located between the first film layer and the second film layer.

[0051] Specifically, a heat-sealing region forming the flow channel 11 is provided between the first film layer and the second film layer.

[0052] When the chip body 1 does not need to be reused, the flow channel 11 can also be disconnected by heat sealing before use. The heat sealing strength of the heat sealing part is lower than that of the heat sealing area so that the flow channel 11 can be easily opened.

[0053] The working principle of this embodiment:

[0054] The chip body 1 is placed on the base 21, and the flow channel 11 spans the control groove 211. When it is necessary to disconnect the flow channel 11, for example, when the flow channel 11 connects two cavities, and when it is not necessary to connect the two cavities, the flow channel 11 needs to be disconnected. At this time, the pressure head 22 is operated to press a part of the chip body 1 into the control groove 211. As a part of the chip body 1 is pressed into the control groove 211, the flow channel 11 is bent multiple times by the pressure head 22 and the control groove 211, thereby making the flow channel 11 in a disconnected state, preventing the two cavities from connecting and making it less prone to leakage at the disconnection point of the flow channel 11.

[0055] This utility model is not limited to the above-mentioned optional embodiments. Under the premise of non-contradiction, the various solutions can be combined arbitrarily. Anyone can derive other forms of products under the guidance of this utility model. However, no matter what changes are made in their shape or structure, all technical solutions that fall within the scope of the claims of this utility model are within the protection scope of this utility model.

Claims

1. A flow channel system for a thin-film microfluidic chip, characterized in that: It includes a chip body with flow channels and a control component for controlling the on / off state of the flow channels; The control component includes a base with a control slot. The control component also includes a pressure head for pressing a portion of the chip body corresponding to a flow channel into the control slot. The chip body is located between the base and the pressure head, and the channel spans the control slot.

2. The flow channel system of a thin-film microfluidic chip according to claim 1, characterized in that: The control groove has a V-shaped cross-section, and the pressure head has a V-shaped cross-section; or, the control groove has a U-shaped cross-section, and the pressure head has a U-shaped cross-section.

3. The flow channel system of a thin-film microfluidic chip according to claim 1, characterized in that: The control groove has a rectangular cross-sectional shape, and the pressure head has a rectangular cross-sectional shape.

4. The flow channel system of a thin-film microfluidic chip according to claim 1, 2, or 3, characterized in that: There are at least two control slots, and at least two control slots are arranged along the length of the flow channel, with each control slot corresponding to a pressure head.

5. The flow channel system of a thin-film microfluidic chip according to claim 1, 2, or 3, characterized in that: The pressure head is provided with a rounded corner to prevent the pressure head from damaging the chip body.

6. The flow channel system of a thin-film microfluidic chip according to claim 1, 2, or 3, characterized in that: The control groove is provided with a rounded corner to make the inner wall of the control groove transition smoothly.

7. The flow channel system of a thin-film microfluidic chip according to claim 1, characterized in that: The control component also includes a driver that drives the pressure head to move up and down relative to the base.

8. The flow channel system of a thin-film microfluidic chip according to claim 7, characterized in that: The driver is an electromagnet, which includes an armature that drives the pressure head, and the pressure head is fixed to the armature by screws.

9. The flow channel system of a thin-film microfluidic chip according to claim 1, characterized in that: The chip body includes a first film layer and a second film layer, and the flow channel is located between the first film layer and the second film layer.

10. The flow channel system of a thin-film microfluidic chip according to claim 9, characterized in that: A heat-sealing region forming the flow channel is provided between the first film layer and the second film layer.

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