Pharmaceutical reaction kettle convenient to clean

Abstract

The utility model relates to the technical field of pharmaceutical reaction kettles, in particular to a pharmaceutical reaction kettle convenient to clean. According to the technical scheme, a top cover is installed on a kettle body, a motor is installed on the top cover, stirring blades are installed below the top cover, the motor is in transmission connection with the stirring blades through a coupler, each stirring blade comprises a rotating shaft, ultrasonic transducers are installed at the positions, located in gaps of the stirring blades, of the rotating shaft, and the ultrasonic transducers are connected with the stirring blades through a coupler. The kettle body comprises a shell and an inner container, a heat exchange interlayer is arranged between the shell and the inner container, and a scraping plate is mounted on the outer side of the stirring blade. According to the utility model, the ultrasonic transducers are arranged at the gaps of the stirring blades, so that material mixing can be enhanced during stirring by utilizing the cavitation effect of ultrasonic waves, and stubborn dirt can be removed in an auxiliary manner during cleaning; and the scraping plate mounted on the outer side can scrape materials attached to the inner wall of the kettle body in time under the driving of the stirring blades, and is matched with the ultrasonic transducer, so that the cleaning effect is greatly improved, and the efficient cleaning and stable operation of the reaction kettle are ensured.

Description

Technical Field

[0001] This utility model relates to the field of pharmaceutical reaction vessel technology, specifically to a pharmaceutical reaction vessel that is easy to clean. Background Technology

[0002] Pharmaceutical reactors are core equipment in the pharmaceutical industry used for key processes such as drug synthesis and purification. Based on the chemical reaction kinetics within a confined space, pharmaceutical reactors enhance mass transfer through stirring, ensuring thorough mixing of materials and accelerating the reaction rate. Simultaneously, heating / cooling systems regulate the reaction temperature, providing suitable thermodynamic conditions to ensure the reaction proceeds in the predetermined direction and rate. Safety accessories function in abnormal situations to guarantee production safety.

[0003] A search revealed that patent application CN218981583U discloses a reaction vessel. Although this device cleans the inner cylinder using a cleaner and rinsing structure, it still has some shortcomings. First, the cleaner has a spiral structure, which may not completely cover all corners of the inner cylinder when there are complex material residues, resulting in incomplete cleaning of some areas and affecting the cleaning effect. Second, the rinsing pipe is only located on the transmission rod, and the distribution of rinsing holes may be limited, making it impossible to thoroughly and evenly rinse the entire inner wall of the cylinder, thus making it difficult to ensure the thoroughness of the cleaning. Utility Model Content

[0004] In view of the shortcomings of the prior art, this utility model provides a pharmaceutical reaction vessel that is easy to clean and solves the problems mentioned in the background art.

[0005] The solution of this utility model to the above-mentioned technical problems is as follows:

[0006] A pharmaceutical reaction vessel that is easy to clean includes a vessel body, a top cover mounted on the vessel body, a motor mounted on the top cover, and a stirring blade mounted below the top cover. The motor is connected to the stirring blade via a coupling.

[0007] The stirring blade includes a rotating shaft, and an ultrasonic transducer is installed on the rotating shaft at the gap between the stirring blade. The vessel body includes an outer shell and an inner liner, and a heat exchange jacket is provided between the outer shell and the inner liner. A scraper is installed on the outer side of the stirring blade.

[0008] Based on the above technical solution, the present invention can be further improved as follows.

[0009] Furthermore, the scraper is provided with a clamping plate, and the clamping plate and the stirring blade are provided with fixing holes. The scraper and the stirring blade are locked and fixed by the fixing holes of the clamping plate and bolts.

[0010] The beneficial effects of adopting the above-mentioned further solutions are:

[0011] This connection method is simple and stable, facilitating the installation and removal of the scraper. During the reaction stage, only the stirring blades are needed for material mixing. When cleaning the inner wall of the vessel is required, the scraper can be quickly installed. If the scraper is worn or damaged, it can be promptly removed for replacement or repair without requiring treatment of the entire stirring blade, reducing maintenance costs and difficulty, and improving the equipment's flexibility and maintenance efficiency.

[0012] Furthermore, the bottom end of the vessel body is provided with a discharge port, which is connected to the interior of the inner liner.

[0013] The beneficial effects of adopting the above-mentioned further solutions are:

[0014] The discharge port is located at the bottom of the reactor body, utilizing gravity to facilitate the smooth discharge of materials after the reaction is complete. Directly connected to the inner liner, it ensures complete discharge, reduces residue, and prevents residual materials from affecting subsequent reactions, thus guaranteeing the independence of each reaction and the stability of product quality. This design also facilitates cleaning and maintenance of the discharge port.

[0015] Furthermore, the vessel body is provided with second connectors on both sides and a first connector at the bottom end, and both the first and second connectors are connected to the heat exchange jacket.

[0016] The beneficial effects of adopting the above-mentioned further solutions are:

[0017] The heat exchange medium, such as hot or cold water, can be easily introduced into the heat exchange jacket via the first and second connectors. The connectors on both sides and the bottom allow for more uniform flow of the heat exchange medium within the jacket, improving the efficiency and uniformity of heat exchange. This helps to precisely control the temperature inside the reactor, providing a stable temperature environment for the reaction, thereby improving reaction stability and product quality.

[0018] Furthermore, a drain pipe is provided at the bottom of the vessel on the side with the discharge port, and the drain pipe is connected to the heat exchange jacket.

[0019] The beneficial effects of adopting the above-mentioned further solutions are:

[0020] The inclusion of a drain pipe facilitates the removal of dirt, impurities, or condensate from the heat exchange jacket. Over time, impurities may accumulate in the heat exchange jacket, affecting heat exchange efficiency. Regularly draining these impurities through the drain pipe maintains the cleanliness of the heat exchange jacket, ensuring proper flow of the heat exchange medium and efficient heat exchange, extending equipment lifespan, and reducing the risk of equipment failure.

[0021] Furthermore, a support base is provided on the outer side of the vessel body, and the vessel body is supported and mounted on the frame by the support base.

[0022] The beneficial effects of adopting the above-mentioned further solutions are:

[0023] The support base provides stable support for the vessel body, allowing it to be firmly mounted on the frame. This structural design increases the stability of the vessel body, reduces the impact of vibrations generated during stirring, and ensures the safe operation of the equipment. At the same time, the support base provides space at the bottom of the vessel body, facilitating the installation of components such as discharge ports and drain pipes, and also promotes air circulation around the vessel body, facilitating heat dissipation and improving the overall performance and reliability of the equipment.

[0024] This invention provides a pharmaceutical reaction vessel that is easy to clean. It has the following beneficial effects:

[0025] A scraper can be installed on the outer side of the stirring blades. During cleaning of the reactor, the scraper effectively removes material adhering to the inner wall of the reactor, preventing long-term accumulation, reducing cleaning difficulty, and improving cleaning efficiency. An ultrasonic transducer is installed on the rotating shaft of the stirring blades at its gaps. During cleaning, the ultrasonic transducer utilizes the cavitation effect of ultrasound to separate the material from the inner wall of the reactor, achieving a more thorough cleaning. A drain pipe is located at the bottom of the reactor and connects to the heat exchange jacket, enabling timely removal of dirt and impurities from the heat exchange jacket, maintaining the cleanliness of the equipment, and preventing impurities from affecting heat exchange efficiency and reagent quality.

[0026] During mixing, only the stirring blades are used to ensure thorough mixing of materials; for cleaning, scrapers are installed as needed to target the inner wall of the vessel. This flexible usage method can adapt to the needs of different pharmaceutical processes, reducing unnecessary operations and lowering labor intensity. The scrapers are fixed to the stirring blades by clamps and bolts, making installation and disassembly convenient. When the scrapers are worn or damaged, they can be quickly replaced without affecting the normal use of the stirring blades, and also facilitating scraper maintenance. Attached Figure Description

[0027] Figure 1 This is a schematic diagram of the main appearance of the present utility model;

[0028] Figure 2 This is a schematic cross-sectional view of the vessel body of this utility model;

[0029] Figure 3 This is a schematic diagram of the appearance of the stirring blade of this utility model;

[0030] Figure 4 This is a schematic diagram of the separation state of the stirring blade and scraper of this utility model.

[0031] Explanation of reference numerals in the attached drawings: 1. Coupling; 10. Stirring blade; 1001. Rotating shaft; 11. Ultrasonic transducer; 2. Support base; 3. First connector; 4. Drain pipe; 5. Second connector; 6. Kettle body; 601. Heat exchange jacket; 602. Discharge port; 603. Outer shell; 604. Inner liner; 7. Top cover; 8. Motor; 9. Scraper; 901. Clamping plate; 902. Fixing hole. Detailed Implementation

[0032] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0033] Please see Figures 1 to 4 As shown, the embodiments provided by this utility model are as follows:

[0034] Example 1

[0035] A pharmaceutical reaction vessel designed for easy cleaning includes a vessel body 6. A support base 2 is provided on the outer side of the vessel body 6, supporting the vessel body 6 on a frame. The support base 2 provides stable support for the vessel body 6, ensuring its secure mounting. This structural design increases the stability of the vessel body 6, reduces the impact of vibrations generated during stirring, and ensures safe operation. Simultaneously, the support base 2 provides space at the bottom of the vessel body 6, facilitating the installation of components such as the discharge port 602 and the drain pipe 4. It also promotes airflow around the vessel body 6, facilitating heat dissipation and improving the overall performance and reliability of the equipment. A top cover 7 is installed on the vessel body 6, and a motor 8 is mounted on the top cover 7. An agitator blade 10 is installed below the top cover 7. The motor 8 is connected to the agitator blade 10 via a coupling 1.

[0036] Example 2

[0037] To further improve the performance, ease of use, and product quality of pharmaceutical reaction vessels, for example, such as Figures 1 to 4As shown, this utility model also includes: a stirring blade 10 including a rotating shaft 1001, an ultrasonic transducer 11 installed on the rotating shaft 1001 at the gap of the stirring blade 10; a vessel body 6 including an outer shell 603 and an inner liner 604; a discharge port 602 provided at the bottom end of the vessel body 6, the discharge port 602 communicating with the interior of the inner liner 604; the discharge port 602 being located at the bottom end of the vessel body 6, utilizing gravity to facilitate the smooth discharge of materials from the vessel body 6 after the reaction is completed; and direct communication with the interior of the inner liner 604, ensuring complete discharge of materials, reducing material residue, avoiding the impact of residual materials on the next reaction, and ensuring the independence of each reaction and the stability of product quality. Meanwhile, this design also facilitates the cleaning and maintenance of the discharge port 602. A heat exchange jacket 601 is provided between the outer shell 603 and the inner liner 604. Second connectors 5 are provided on both sides of the vessel body 6, and a first connector 3 is provided at the bottom of the vessel body 6. Both the first connector 3 and the second connector 5 are connected to the heat exchange jacket 601. Through the connection between the first connector 3 and the second connector 5 and the heat exchange jacket 601, heat exchange media of different temperatures, such as hot water or cold water, can be easily introduced into the heat exchange jacket 601. The connector design on both sides and at the bottom allows the heat exchange media to flow more evenly in the heat exchange jacket 601, improving the efficiency and uniformity of heat exchange. This helps to accurately control the temperature inside the vessel, providing a stable temperature environment for the reaction, thereby improving the stability of the reaction and the quality of the product. A drain pipe 4 is provided at the bottom of the vessel body 6 on the side with the discharge port 602. The drain pipe 4 is connected to the heat exchange jacket 601, and the drain pipe 4 facilitates the discharge of dirt, impurities, or condensate from the heat exchange jacket 601. As usage time increases, impurities may accumulate in the heat exchange jacket 601, affecting heat exchange efficiency. Regularly draining these impurities through the drain pipe 4 maintains the cleanliness of the heat exchange jacket 601, ensuring normal flow of the heat exchange medium and heat exchange efficiency, extending equipment lifespan, and reducing the risk of equipment failure. A scraper 9 is installed on the outer side of the stirring blade 10. The scraper 9 has a clamping plate 901, and fixing holes 902 are formed through both the clamping plate 901 and the stirring blade 10. The scraper 9 and stirring blade 10 are secured together using the fixing holes 902 of the clamping plate 901 and bolts. This connection method is simple and stable, facilitating the installation and removal of the scraper 9. During the reaction stage, only the stirring blade 10 can be used for material stirring. When cleaning the inner wall of the vessel 6 is required, the scraper 9 can be quickly installed. If the scraper 9 becomes worn or damaged, it can be promptly removed for replacement or repair without requiring overall treatment of the stirring blade 10, reducing maintenance costs and difficulty, and improving the equipment's operational flexibility and maintenance efficiency.

[0038] Working principle:

[0039] Open the top cover 7 and add the raw materials into the inner liner 604 of the reactor body 6. This is because the reactor body 6 serves as the main reaction site, and the inner liner 604 is used to contain the reactants and provide space for the reaction.

[0040] When motor 8 is turned on, it drives the shaft 1001 of stirring blade 10 to rotate via coupling 1, and stirring blade 10 begins to stir the raw materials inside the vessel body 6. The rotation of stirring blade 10 creates convection and turbulence in the material inside the vessel body 6, allowing different materials to come into full contact and accelerating the reaction. According to the temperature conditions required for the reaction, a suitable heat exchange medium (such as hot or cold water) is introduced into the heat exchange jacket 601 through the first connector 3 and the second connector 5. Due to the structure of the heat exchange jacket 601 between the outer shell 603 and the inner liner 604, the heat exchange medium exchanges heat with the material in the inner liner 604, thereby precisely controlling the temperature inside the vessel and creating a suitable thermal environment for the reaction.

[0041] The ultrasonic transducer 11 can be activated according to the reaction conditions. The ultrasonic transducer 11 utilizes the cavitation effect of ultrasound to generate tiny bubbles in the material and rapidly break them, forming local high temperature, high pressure and strong shock waves, which further promotes the mixing and reaction of the material and improves the reaction efficiency and effect.

[0042] Once the reaction has reached the desired effect, open the discharge port 602 to discharge the reacted material from the reactor body 6. This is because the discharge port 602 is connected to the inner liner 604, allowing the material to be discharged smoothly.

[0043] If material adheres to the inner wall of the vessel body 6, a scraper 9 can be installed. The scraper 9 is fixed to the stirring blade 10 by a clamping plate 901 and bolts. As the stirring blade 10 rotates, the scraper 9 scrapes the inner wall of the vessel body 6, removing the adhered material. At the same time, the ultrasonic transducer 11 can be turned on again to use the cavitation effect of ultrasound to assist in cleaning, separating the material from the inner wall of the vessel body 6 for a more thorough cleaning. Open the drain pipe 4 to discharge the dirt and impurities in the heat exchange jacket 601, ensuring the cleanliness of the heat exchange jacket 601 and good heat exchange performance.

[0044] After cleaning, turn off the motor 8, ultrasonic transducer 11 and other equipment, remove the scraper 9 and store it properly to prepare for the next reaction.

[0045] The foregoing has shown and described the basic principles, main features, and advantages of this utility model. It will be apparent to those skilled in the art that this utility model is not limited to the details of the exemplary embodiments described above, and that it can be implemented in other specific forms without departing from the spirit or basic characteristics of this utility model. Therefore, the embodiments should be considered exemplary and non-limiting in all respects. The scope of this utility model is defined by the appended claims rather than the foregoing description, and thus all variations falling within the meaning and scope of equivalents of the claims are intended to be included within this utility model. No reference numerals in the claims should be construed as limiting the scope of the claims.

[0046] Furthermore, it should be understood that although this specification describes embodiments, not every embodiment contains only one independent technical solution. This narrative style is merely for clarity. Those skilled in the art should consider the specification as a whole, and the technical solutions in each embodiment can also be appropriately combined to form other embodiments that can be understood by those skilled in the art.

Claims

1. A pharmaceutical reaction vessel that is easy to clean, comprising a vessel body (6), a top cover (7) mounted on the vessel body (6), a motor (8) mounted on the top cover (7), and a stirring blade (10) mounted below the top cover (7), wherein the motor (8) is connected to the stirring blade (10) via a coupling (1), characterized in that: The stirring blade (10) includes a rotating shaft (1001), and an ultrasonic transducer (11) is installed on the rotating shaft (1001) at the gap of the stirring blade (10). The vessel body (6) includes an outer shell (603) and an inner liner (604), and a heat exchange jacket (601) is provided between the outer shell (603) and the inner liner (604). A scraper (9) is installed on the outer side of the stirring blade (10).

2. The pharmaceutical reaction vessel that is easy to clean according to claim 1, characterized in that: The scraper (9) is provided with a clamping plate (901), and a fixing hole (902) is provided through the clamping plate (901) and the stirring blade (10). The scraper (9) and the stirring blade (10) are locked and fixed by the fixing hole (902) of the clamping plate (901) and the bolt.

3. The pharmaceutical reaction vessel that is easy to clean according to claim 1, characterized in that: The bottom end of the vessel body (6) is provided with a discharge port (602), which is connected to the interior of the inner liner (604).

4. The pharmaceutical reaction vessel that is easy to clean according to claim 1, characterized in that: The vessel body (6) is provided with second connectors (5) on both sides and a first connector (3) at the bottom end. Both the first connector (3) and the second connector (5) are connected to the heat exchange jacket (601).

5. The pharmaceutical reaction vessel that is easy to clean according to claim 1, characterized in that: The bottom end of the vessel body (6) is provided with a drain pipe (4) on the side with the discharge port (602), and the drain pipe (4) is connected to the heat exchange jacket (601).

6. The pharmaceutical reaction vessel that is easy to clean according to claim 1, characterized in that: The outer side of the vessel body (6) is provided with a support base (2), and the vessel body (6) is supported and mounted on the frame by the support base (2).

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