Rapid sample pretreatment instrument for acetylpyrazine detection

Abstract

The utility model discloses a rapid sample pretreatment instrument for acetylpyrazine detection, and relates to the technical field of acetylpyrazine detection. The device comprises a cylinder body, a panel is inserted into the top of the cylinder body, an extraction assembly is arranged above the panel, a pipeline is fixedly connected to the right side of the cylinder body, a pressure gauge is installed on the pipeline, a waste liquid tank is inserted into the cylinder body, and the left side and the right side of the inner wall of the waste liquid tank are each fixedly connected with two positioning insertion strips. A sample placing rack is inserted into the waste liquid tank through four positioning insertion strips. The positioning insertion strips are arranged, specifically, the waste liquid tank is placed in the cylinder body, the sample placement frame is inserted into the waste liquid tank, and the sample placement frame is positioned through the positioning insertion strips on the inner wall of the waste liquid tank, so that the waste liquid tank and the sample placement frame can be placed at the same time, and liquid cannot be influenced to enter the waste liquid tank; therefore, the frequency of opening the panel is reduced, and the working efficiency during extraction is improved.

Description

Technical Field

[0001] This invention belongs to the field of acetylpyrazine detection technology, and in particular relates to a rapid sample pretreatment instrument for acetylpyrazine detection. Background Technology

[0002] The detection of acetylpyrazine usually requires sample pretreatment to improve the accuracy and sensitivity of the detection. Solid phase extraction is usually used for the pretreatment of acetylpyrazine.

[0003] Existing solid phase extraction equipment typically includes multiple structures. During the extraction process, the panel needs to be opened frequently, and the waste liquid tank and sample rack need to be removed and placed separately. This not only increases the number of steps in the extraction process, but also makes the pretreatment process more cumbersome, thereby reducing work efficiency. Therefore, we propose a rapid sample pretreatment instrument for the detection of acetylpyrazine. Utility Model Content

[0004] The purpose of this invention is to provide a rapid sample pretreatment instrument for the detection of acetylpyrazine. By setting positioning strips, specifically placing the waste liquid tank inside the cylinder, and inserting the sample holder into the waste liquid tank, the sample holder is positioned by the positioning strips on the inner wall of the waste liquid tank. At this time, the waste liquid tank and the sample holder can be placed simultaneously without affecting the liquid entering the waste liquid tank, thereby reducing the number of times the panel needs to be opened and improving the working efficiency during extraction. This solves the problem that existing solid phase extraction equipment requires frequent opening of the panel and separate handling of the waste liquid tank and sample holder during the extraction process, which not only increases the number of steps in the extraction process but also makes the pretreatment process cumbersome.

[0005] To solve the above-mentioned technical problems, this utility model is achieved through the following technical solution:

[0006] This invention relates to a rapid sample pretreatment instrument for the detection of acetylpyrazine, comprising a cylinder, a panel inserted into the top of the cylinder, an extraction assembly disposed above the panel, a pipe fixedly connected to the right side of the cylinder, a pressure gauge installed on the pipe, a waste liquid tank inserted inside the cylinder, two positioning strips fixedly connected to the left and right sides of the inner wall of the waste liquid tank, a sample holder inserted into the waste liquid tank via four positioning strips, a horizontal plate fixedly connected to the front and back of the sample holder, a support plate fixedly connected to the bottom of each of the two horizontal plates, and several insertion holes opened inside the horizontal plates; the support plate is used to support the test tubes, improving the stability of the test tubes, and the insertion holes can limit the insertion of the test tubes; the strips are used to position the sample holder.

[0007] Furthermore, the extraction assembly includes several connecting tubes fixedly connected to the panel. A solid-phase extraction column is inserted into the top of each connecting tube. A limiting ring is fitted around the outside of the solid-phase extraction column. A support frame is fixedly connected to the surface of the limiting ring. The bottom of the support frame is fixedly connected to the top of the panel. The top of the connecting tube is made of silicone material and has elasticity. When the solid-phase extraction column is inserted, it can improve the fixing effect of the solid-phase extraction column.

[0008] Furthermore, an adjusting ring is slidably connected inside the connecting pipe, and several grooves are opened on the outer side of the adjusting ring. A conical block is fixedly connected to the bottom of the inner wall of the adjusting ring, and a connecting frame is fixedly connected to the bottom of the adjusting ring. A straight groove is opened inside the connecting frame. The conical block plays a guiding role, improves the unloading rate, and reduces the occurrence of residue.

[0009] Furthermore, a handle is provided on the outside of the connecting pipe, and a rotating rod is fixedly connected to the side of the handle facing the connecting pipe. The rotating rod passes through the connecting pipe and extends into it. The rotating rod is rotatably connected to the connecting pipe through a damping shaft. A turntable is fixedly connected to the side of the rotating rod facing the adjusting ring, and a push shaft is fixedly connected to the side of the turntable away from the rotating rod. The push shaft is slidably limited and fitted into a straight groove on the connecting frame. Since the rotating rod is connected to the connecting pipe through the damping shaft, the handle will not rotate on its own after being rotated.

[0010] Furthermore, the bottom of the connecting pipe penetrates through the panel and extends to the outside, the insertion hole on the horizontal plate corresponds to the connecting pipe, a sealing ring is fitted on the bottom of the panel, the bottom of the panel contacts the top of the cylinder through the sealing ring, and the pipe is interconnected with the cylinder; the pipe is used to connect to a vacuum pump, thereby playing a role in evacuating the cylinder.

[0011] This utility model has the following beneficial effects:

[0012] 1. This utility model, by setting a positioning strip, specifically places the waste liquid tank inside the cylinder, inserts the sample placement rack into the waste liquid tank, and positions the sample placement rack by the positioning strip on the inner wall of the waste liquid tank. At this time, the waste liquid tank and the sample placement rack can be placed simultaneously without affecting the liquid entering the waste liquid tank, thereby reducing the number of times the panel needs to be opened and improving the working efficiency during extraction.

[0013] 2. This utility model uses an adjusting ring. Specifically, when the top of the connecting pipe needs to be sealed, turning the handle drives the turntable to rotate via the rotating rod. The push shaft pushes the adjusting ring upward, allowing the groove to enter the connecting pipe. Since the adjusting ring is circular and the top of the connecting pipe is elastic, the sealing effect is higher, reducing overflow.

[0014] Of course, any product implementing this utility model does not necessarily need to achieve all of the advantages described above at the same time. Attached Figure Description

[0015] To more clearly illustrate the technical solutions of the embodiments of this utility model, the accompanying drawings used in the description of the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments of this utility model. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0016] Figure 1 This is a schematic diagram of the overall structure of this utility model;

[0017] Figure 2 This is a schematic diagram of the internal cross-sectional structure of the connecting pipe of this utility model;

[0018] Figure 3 This utility model Figure 2 A magnified structural diagram of A in the middle;

[0019] Figure 4 This is a front view cross-sectional structural diagram of the cylinder block of this utility model;

[0020] Figure 5 This is a schematic diagram of the overall structure of the sample placement rack of this utility model.

[0021] The attached diagram lists the components represented by each number as follows:

[0022] 1. Cylinder body; 11. Panel; 12. Extraction assembly; 121. Connecting pipe; 211. Adjusting ring; 212. Conical block; 213. Connecting frame; 122. Solid phase extraction column; 123. Limiting ring; 124. Support frame; 125. Rotary handle; 251. Rotating rod; 252. Turntable; 253. Push shaft; 13. Waste liquid tank; 131. Positioning insert; 14. Sample placement rack; 141. Horizontal plate; 142. Support plate; 143. Insertion hole; 2. Pipe; 21. Pressure gauge. Detailed Implementation

[0023] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the scope of protection of the present utility model.

[0024] Please see Figures 1-5As shown, this utility model is a rapid sample pretreatment instrument for the detection of acetylpyrazine, including a cylinder 1, a panel 11 inserted into the top of the cylinder 1, an extraction component 12 disposed above the panel 11, a pipe 2 fixedly connected to the right side of the cylinder 1, a pressure gauge 21 installed on the pipe 2, a waste liquid tank 13 inserted into the inside of the cylinder 1, two positioning strips 131 fixedly connected to the left and right sides of the inner wall of the waste liquid tank 13, and a sample placement rack 14 inserted into the inside of the waste liquid tank 13 through four positioning strips 131, with the sample placement rack 14 fixedly connected to the front and back. There are two horizontal plates 141, and support plates 142 are fixedly connected to the bottom of each horizontal plate 141. Several insertion holes 143 are opened inside the horizontal plates 141. The waste liquid tank 13 is placed inside the cylinder 1. The sample placement rack 14 is inserted into the waste liquid tank 13 and positioned by the positioning strip 131 on the inner wall of the waste liquid tank 13. At this time, the waste liquid tank 13 and the sample placement rack 14 can be placed at the same time without affecting the liquid entering the waste liquid tank 13, thereby reducing the number of times the panel 11 is opened and improving the working efficiency during extraction.

[0025] The extraction assembly 12 includes several connecting tubes 121 fixedly connected to the panel 11. A solid phase extraction column 122 is inserted into the top of the connecting tube 121. A limiting ring 123 is sleeved on the outside of the solid phase extraction column 122. A support frame 124 is fixedly connected to the surface of the limiting ring 123. The bottom of the support frame 124 is fixedly connected to the top of the panel 11.

[0026] An adjusting ring 211 is slidably connected inside the connecting pipe 121. Several grooves are provided on the outer side of the adjusting ring 211. A conical block 212 is fixedly connected to the bottom of the inner wall of the adjusting ring 211. A connecting frame 213 is fixedly connected to the bottom of the adjusting ring 211. A straight groove is provided inside the connecting frame 213. When it is necessary to seal the top of the connecting pipe 121, the handle 125 is turned, which drives the turntable 252 to rotate through the rotating rod 251. The push shaft 253 pushes the adjusting ring 211 upward, so that the grooves enter the connecting pipe 121. Since the adjusting ring 211 is circular and the top of the connecting pipe 121 is elastic, the sealing effect is higher and the overflow is reduced.

[0027] A handle 125 is provided on the outside of the connecting pipe 121. A rotating rod 251 is fixedly connected to the side of the handle 125 facing the connecting pipe 121. The rotating rod 251 passes through the connecting pipe 121 and extends into it. The rotating rod 251 is rotatably connected to the connecting pipe 121 through a damping rotating shaft. A turntable 252 is fixedly connected to the side of the rotating rod 251 facing the adjusting ring 211. A push shaft 253 is fixedly connected to the side of the turntable 252 away from the rotating rod 251. The push shaft 253 is slidably limited and fitted in the straight groove on the connecting frame 213.

[0028] The bottom of the connecting pipe 121 passes through the panel 11 and extends to the outside. The insertion hole 143 on the horizontal plate 141 corresponds to the connecting pipe 121. A sealing ring is fitted at the bottom of the panel 11. The bottom of the panel 11 contacts the top of the cylinder 1 through the sealing ring. The pipe 2 and the cylinder 1 are interconnected.

[0029] One specific application of this embodiment is:

[0030] In use, first place the waste liquid tank 13 inside the cylinder 1, then insert the sample placement rack 14 into the waste liquid tank 13, and position the sample placement rack 14 using the positioning strip 131 on the inner wall of the waste liquid tank 13. This allows the waste liquid tank 13 and sample placement rack 14 to be placed simultaneously, reducing the number of times the panel 11 needs to be opened. Then, cover the cylinder 1 with the panel 11, and connect the pipe 2 to the vacuum pump. The pressure gauge 21 is used to display the vacuum pressure. The vacuum pump extracts air from the cylinder 1. Next, insert the solid-phase extraction column 122 into the limiting ring 123, and insert the bottom into the top of the connecting tube 121. Since the top of the connecting tube 121 is made of silicone material and has elasticity, the solid-phase extraction column 122 is fixed to the top of the connecting tube 121. The limiting ring 123 then holds the solid-phase extraction column in place. The extraction column 122 serves as a limit to prevent the solid-phase extraction column 122 from falling off. Then, the activation liquid is poured into the solid-phase extraction column 122. Then, the handle 125 is turned, which drives the turntable 252 to rotate through the rotating rod 251. The push shaft 253 will pull the adjusting ring 211 downward. At this time, the groove on the adjusting ring 211 is exposed, thereby discharging the waste activation liquid and dropping it into the waste liquid tank 13 in the cylinder 1. Since the rotating rod 251 is connected to the connecting pipe 121 through the damping rotating shaft, the handle 125 will not rotate on its own after being turned. After the waste liquid is discharged, the handle 125 is turned in the opposite direction, so that the adjusting ring 211 is inserted into the top pipe of the connecting pipe 121, thereby sealing it. Since the adjusting ring 211 is circular, the sealing effect is better and the overflow is reduced.

[0031] The acetylpyrazine sample is then injected into the solid-phase extraction column 122. After injection, the connecting tube 121 is opened to allow the liquid to drain into the waste liquid tank 13. The connecting tube 121 is then closed, and rinsing is performed. The number of rinsing cycles and reagents are selected according to the sample. After completion, the pressure in the cylinder 1 is released, and the panel 11 is opened. The test tube is then inserted into the insertion hole 143 on the horizontal plate 141, so that the bottom of the test tube contacts the support plate 142. The test tube is then placed at the bottom of the corresponding connecting tube 121. After placement, the panel 11 is placed on the cylinder 1, and the cylinder 1 is then vacuumed. Finally, elution is performed, and the pretreated sample flows into the test tube, completing the pretreatment. The pressure in the cylinder 1 is then released, the panel 11 is opened, and the test tube is removed for subsequent testing. The sample placement rack 14 and the waste liquid tank 13 are then removed.

[0032] In the description of this specification, references to terms such as "an embodiment," "example," "specific example," etc., indicate that a specific feature, structure, material, or characteristic described in connection with that embodiment or example is included in at least one embodiment or example of the present invention. In this specification, the illustrative expressions of the above terms do not necessarily refer to the same embodiment or example. Furthermore, the specific features, structures, materials, or characteristics described may be combined in any suitable manner in one or more embodiments or examples.

[0033] The preferred embodiments of this utility model disclosed above are merely illustrative of the present utility model. These preferred embodiments do not exhaustively describe all details, nor do they limit the present utility model to the specific implementations described. Clearly, many modifications and variations can be made based on the content of this specification. This specification selects and specifically describes these embodiments to better explain the principles and practical applications of the present utility model, thereby enabling those skilled in the art to better understand and utilize it. This utility model is limited only by the claims and their full scope and equivalents.

Claims

1. A rapid sample pretreatment instrument for acetylpyrazine detection, comprising a cylinder (1), wherein a panel (11) is inserted into the top of the cylinder (1), characterized in that: An extraction assembly (12) is provided above the panel (11). A pipe (2) is fixedly connected to the right side of the cylinder (1). A pressure gauge (21) is installed on the pipe (2). A waste liquid tank (13) is inserted inside the cylinder (1). Two positioning strips (131) are fixedly connected to the left and right sides of the inner wall of the waste liquid tank (13). A sample placement rack (14) is inserted inside the waste liquid tank (13) through four positioning strips (131). A horizontal plate (141) is fixedly connected to the front and back of the sample placement rack (14). A support plate (142) is fixedly connected to the bottom of the two horizontal plates (141). Several insertion holes (143) are opened inside the horizontal plate (141).

2. The rapid sample pretreatment instrument for acetylpyrazine detection according to claim 1, characterized in that, The extraction assembly (12) includes several connecting tubes (121) fixedly connected to the panel (11). A solid phase extraction column (122) is inserted into the top of the connecting tube (121). A limiting ring (123) is sleeved on the outside of the solid phase extraction column (122). A support frame (124) is fixedly connected to the surface of the limiting ring (123). The bottom of the support frame (124) is fixedly connected to the top of the panel (11).

3. The rapid sample pretreatment instrument for acetylpyrazine detection according to claim 2, characterized in that, The connecting pipe (121) is slidably connected to an adjusting ring (211). Several grooves are opened on the outside of the adjusting ring (211). A conical block (212) is fixedly connected to the bottom of the inner wall of the adjusting ring (211). A connecting frame (213) is fixedly connected to the bottom of the adjusting ring (211). A straight groove is opened inside the connecting frame (213).

4. The rapid sample pretreatment instrument for acetylpyrazine detection according to claim 3, characterized in that, A handle (125) is provided on the outside of the connecting pipe (121). A rotating rod (251) is fixedly connected to the side of the handle (125) facing the connecting pipe (121). The rotating rod (251) passes through the connecting pipe (121) and extends into the interior. The rotating rod (251) is rotatably connected to the connecting pipe (121) through a damping shaft.

5. The rapid sample pretreatment instrument for acetylpyrazine detection according to claim 4, characterized in that, The rotating rod (251) is fixedly connected to a turntable (252) on the side facing the adjusting ring (211), and a push shaft (253) is fixedly connected to the side of the turntable (252) away from the rotating rod (251). The push shaft (253) is slidably limited and fitted in the straight groove on the connecting frame (213).

6. The rapid sample pretreatment instrument for acetylpyrazine detection according to claim 4, characterized in that, The bottom of the connecting tube (121) passes through the panel (11) and extends to the outside, and the insertion hole (143) on the horizontal plate (141) corresponds to the connecting tube (121).

7. The rapid sample pretreatment instrument for acetylpyrazine detection according to claim 4, characterized in that, A sealing ring is fitted at the bottom of the panel (11), and the bottom of the panel (11) contacts the top of the cylinder (1) through the sealing ring. The pipe (2) is connected to the cylinder (1).

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