Sample pretreatment equipment

Abstract

The utility model provides sample pretreatment equipment, which is characterized in that a shell comprises a treatment cavity with a pipe hole, and the pipe hole is used for allowing detection consumables to pass through; the uniform mixing mechanism comprises a fixing frame and a uniform mixing driving part connected with the fixing frame, the fixing frame is used for fixing the detection consumables, and the uniform mixing driving part is used for driving the fixing frame to rotate along the axis of the fixing frame and uniformly mixing a solution in the detection consumables; the turning cover mechanism comprises a pretreatment turning cover with a push rod, and the pretreatment turning cover is used for blocking or opening the pipe hole; the lifting mechanism is used for driving the uniform mixing mechanism to lift, so that the detection consumables abut against or avoid the push rod; and the uniform mixing detector is used for detecting the rotation times of the fixing frame. According to the utility model, high-precision full-automatic sample pretreatment in a closed space is realized, the treatment efficiency is improved, the treatment effect can be ensured, and the condition that the sample pretreatment is not in place due to the fact that the mixing state is identified by naked eyes can be avoided.

Description

Technical Field

[0001] This utility model belongs to the field of sample pretreatment technology, and in particular relates to a sample pretreatment device. Background Technology

[0002] Nucleic acids are the carriers of genetic information in living organisms and are essential components of all known life forms. There are two main types of nucleic acids: DNA and RNA, which are primarily found in the cell nucleus and exist in a state bound to proteins. With the rapid development of molecular biology, the research and analysis of nucleic acids are increasingly being promoted and applied in fields such as clinical diagnosis, food safety, environmental monitoring, and agriculture, forestry, and animal husbandry.

[0003] Before conducting nucleic acid testing, samples and reagents need to be mixed and pretreated. Existing sample pretreatment devices cannot realize all the workflows of sample pretreatment, and some processes need to be operated manually, resulting in poor sample pretreatment effect and low processing efficiency. Utility Model Content

[0004] The main purpose of this invention is to propose a sample pretreatment device, which aims to solve the technical problems of poor sample pretreatment effect and low processing efficiency in the prior art.

[0005] To achieve the above objectives, this utility model provides a sample pretreatment device for a testing consumable for push-filling samples, comprising: a shell including a processing chamber with a tube hole for the testing consumable to pass through; a mixing mechanism including a fixing frame and a mixing drive connected to the fixing frame, the fixing frame for fixing the testing consumable, and the mixing drive for driving the fixing frame to rotate along its own axis and mixing the solution in the testing consumable; a flip-top mechanism including a pretreatment flip-top with a push rod for sealing or opening the tube hole; a lifting mechanism connected to the mixing mechanism, the lifting mechanism for driving the mixing mechanism to rise and fall, so that the testing consumable abuts against or avoids the push rod; and a mixing detector for detecting the number of rotations of the fixing frame.

[0006] In this embodiment of the utility model, the fixing frame includes: a hollow tube with a cavity for accommodating testing consumables, the upper and lower ends of the hollow tube being open and the side wall having a clamping notch; and a clamping spring piece, installed on the hollow tube and extending into the cavity through the clamping notch, the clamping spring piece being used to elastically press the testing consumables.

[0007] In this embodiment of the utility model, the hollow tube includes: a limiting section for limiting the detection consumable; and a main body section connected to the bottom of the limiting section, wherein the clamping notch is formed in the main body section, and the cross-sectional dimension of the main body section is larger than the cross-sectional dimension of the limiting section.

[0008] In this embodiment of the utility model, the pretreatment flip cover includes: a sealing part for sealing or opening the tube hole; a limiting part connected to the bottom of the sealing part, the cross-sectional dimension of the limiting part being larger than the cross-sectional dimension of the sealing part; a push rod disposed at the bottom of the limiting part; and a top plate with a limiting groove installed on the top of the outer shell, the limiting groove being used for limiting cooperation with the limiting part.

[0009] In this embodiment of the present invention, the flip-cover mechanism further includes a flip-cover driving component connected to the pre-processing flip-cover. The flip-cover driving component is used to drive the pre-processing flip-cover away from or close to the tube hole. The sample pre-processing device further includes a vertically extending flip-cover fixing plate. The flip-cover driving component is installed on the flip-cover fixing plate. The top plate has a positioning groove for the flip-cover fixing plate to extend into.

[0010] In this embodiment of the utility model, at least two of the flip cover fixing plates are arranged sequentially along the shell length direction of the outer shell, and an installation space is formed between any two adjacent flip cover fixing plates. Two flip cover driving members are installed opposite each other in the installation space, and the number of the mixing mechanism, the flip cover mechanism and the lifting mechanism is the same.

[0011] In this embodiment of the utility model, a vertically arranged main mounting plate is also provided inside the processing cavity, a guide rail is provided on the main mounting plate, and a guide groove is provided on the mixing mechanism to guide and cooperate with the guide rail.

[0012] In this embodiment of the utility model, the lifting mechanism includes: a lifting rack connected to the mixing mechanism; and a lifting drive unit installed on the main mounting plate, wherein the output end of the lifting drive unit is provided with a gear that meshes with the lifting rack.

[0013] In this embodiment of the present invention, the sample pretreatment device further includes an avoidance detector disposed near the bottom of the outer shell, and a first baffle is disposed on the mixing mechanism, the avoidance detector being used to detect the first baffle.

[0014] In this embodiment of the present invention, the sample pretreatment device further includes a flip-top detector, the flip-top mechanism is provided with a second baffle, and the flip-top detector is used to detect the second baffle located at the open position.

[0015] Through the above technical solution, the sample pretreatment device provided by this utility model embodiment has the following beneficial effects:

[0016] When using a sample pretreatment device to pretreatment the sample in the testing consumables, the pretreatment flip cover can move relative to the tube hole 11 under drive, so that the pretreatment flip cover opens the tube hole. The lifting mechanism can drive the mixing mechanism to rise to the working position, so that the operator can put the testing consumables into the fixed frame in the processing chamber through the tube hole. The lifting mechanism can drive the mixing mechanism to fall to the avoidance position, so that the fixed frame and the testing consumables avoid the pretreatment flip cover. If interference with the pretreatment flip cover can be avoided, the pretreatment flip cover can be driven to reset to the sealing position, so that the pretreatment flip cover closes the tube hole, making the processing chamber a sealed space, which can prevent the subsequent sample pretreatment from being interfered with by the external environment. The lifting mechanism can drive the mixing mechanism to rise to the working position, so that the push rod on the pretreatment cover can push and add the test consumables. After that, the lifting mechanism can drive the mixing mechanism to fall to the avoidance position. The mixing drive of the mixing mechanism can drive the fixed frame to rotate along the central axis of the test consumables. The rotation angle can be set according to actual usage requirements. During the mixing process, the mixing detector can detect the number of mixing cycles of the fixed frame. When the mixing detector detects that the number of mixing cycles has reached a specified number, the mixing drive can rotate the test consumables to the avoidance state. The test consumables in the avoidance state are set horizontally, which can avoid the test consumables interfering with the cover mechanism. The pretreatment cover can be driven to open the tube hole. The mixing drive can drive the test consumables to return to the vertical position. The lifting mechanism can drive the mixing mechanism to rise to the working position, so that the operator can take the processed test consumables through the tube hole. This invention enables the mixing of testing consumables within a sealed space through a mixing mechanism, a flip-top mechanism, and a lifting mechanism. It eliminates the need for manual opening and closing of the cover, manual pushing and adding of the testing consumables, and manual mixing. Furthermore, it allows for precise detection of the mixing state through a mixing detector. Only manual placement and retrieval of the testing consumables are required, truly achieving high-precision, fully automated sample pretreatment within a sealed space. This improves processing efficiency while ensuring processing effectiveness, avoiding situations where sample pretreatment is inadequate due to visual identification of the mixing state.

[0017] Other features and advantages of this invention will be described in detail in the following detailed description section. Attached Figure Description

[0018] The accompanying drawings are provided to illustrate the present invention and form part of the specification. They are used together with the following detailed description to explain the present invention, but do not constitute a limitation thereof. In the drawings:

[0019] Figure 1 This is a schematic diagram of the sample pretreatment device according to one embodiment of the present invention;

[0020] Figure 2 This is a partial structural schematic diagram of a sample pretreatment device according to an embodiment of the present invention;

[0021] Figure 3 This is a schematic diagram of the flip-top mechanism of a sample pretreatment device according to an embodiment of the present invention;

[0022] Figure 4 This is a partial structural schematic diagram of a sample pretreatment device according to an embodiment of the present invention.

[0023] Explanation of reference numerals in the attached figures

[0024] Label Name Label Name

[0025] 100 Sample pretreatment equipment 313 Limiting part

[0026] 1. Outer shell 32. Flip-top drive unit

[0027] 11 Pipe hole 33 Second baffle

[0028] 2. Mixing mechanism 4. Lifting mechanism

[0029] 21 Fixed frame 41 Lifting rack

[0030] 211 Hollow tube 42 Lifting drive component

[0031] 212 Clamping notch 5 Mixing detector

[0032] 213 Limiting section 6 Top plate

[0033] 214 Main body section 61 Limiting groove

[0034] 215 Clamping spring 7 Flip cover fixing plate

[0035] 22 Mixing drive unit 8 Main mounting plate

[0036] 23 First baffle 81 Guide rail

[0037] 3 Flip-top mechanism; 9 Collision avoidance detector.

[0038] 31 Pre-treatment flip cover 10 Flip cover detector

[0039] 311 Push rod 200 testing consumables

[0040] 312 Sealing part Detailed Implementation

[0041] The specific embodiments of this utility model will be described in detail below with reference to the accompanying drawings. It should be understood that the specific embodiments described herein are for illustration and explanation only and are not intended to limit the scope of this utility model.

[0042] The sample pretreatment device according to the present invention is described below with reference to the accompanying drawings.

[0043] like Figures 1 to 4 As shown in the embodiment of this utility model, the detection consumable 200 for pushing and adding samples, and the sample pretreatment device 100 include a housing 1, a mixing mechanism 2, a flip-top mechanism 3, a lifting mechanism 4, and a mixing detector 5. The housing 1 includes a processing cavity with a tube hole 11 for the detection consumable 200 to pass through. The mixing mechanism 2 includes a fixing frame 21 and a mixing drive 22 connected to the fixing frame 21. The fixing frame 21 is used to fix the detection consumable 200, and the mixing drive 22 is used to drive the fixing frame 21 to rotate along its own axis and mix the solution in the detection consumable 200. The flip-top mechanism 3 includes a pretreatment flip-top 31 with a push rod 311, which is used to block or open the tube hole 11. The lifting mechanism 4 is connected to the mixing mechanism 2 and is used to drive the mixing mechanism 2 to rise and fall, so that the detection consumable 200 abuts against or avoids the push rod 311. The mixing detector 5 is used to detect the number of rotations of the fixing frame 21. In one embodiment, the flip-top mechanism 3 further includes a flip-top drive 32 connected to the pre-processing flip-top 31, the flip-top drive 32 being used to drive the pre-processing flip-top 31 away from or towards the tube hole 11. In another embodiment, the pre-processing flip-top 31 can be moved manually.

[0044] Understandably, the testing consumable 200 contains samples and testing reagents, and the samples and reagents within the testing consumable 200 can be mixed by pushing from top to bottom. The testing consumable 200 can adopt a push-tube structure as used in the prior art. In this embodiment, the mixing drive 22 and the flip-top drive 32 can both be motors as used in the prior art. In one embodiment, the mixing detector 5 can be a photoelectric sensor, and the fixing frame 21 can be provided with a baffle structure that can extend into the photoelectric sensor. In other embodiments, the mixing detector 5 can be other detection structures.

[0045] When the sample pretreatment device 100 in this embodiment pretreatments the sample in the test consumable 200, the pretreatment flip cover 31 can move relative to the tube hole 11 under the drive, so that the pretreatment flip cover 31 opens the tube hole 11. The lifting mechanism 4 can drive the mixing mechanism 2 to rise to the working position, so that the operator can put the test consumable 200 into the fixed frame 21 in the processing chamber through the tube hole 11. The lifting mechanism 4 can drive the mixing mechanism 2 to fall to the avoidance position, so that the fixed frame 21 and the test consumable 200 avoid the pretreatment flip cover 31. In the case of avoiding interference with the pretreatment flip cover 31, the pretreatment flip cover 31 can be driven to reset to the sealing position, so that the pretreatment flip cover 31 closes the tube hole 11, making the processing chamber a sealed space, which can prevent the subsequent sample pretreatment from being interfered with by the external environment. The lifting mechanism 4 can drive the mixing mechanism 2 to rise to the working position, so that the push rod 311 on the pretreatment flip cover 31 pushes the test consumable 200 to perform a sample addition operation. After that, the lifting mechanism 4 can drive the mixing mechanism 2 to fall to the avoidance position. The mixing drive component 22 of the mixing mechanism 2 can drive the fixed frame 21 to rotate along the central axis of the test consumable 200. The rotation angle can be set according to actual usage requirements. During the mixing process, the mixing detector 5 can detect the number of mixing cycles of the fixed frame 21. When the mixing detector 5 detects... When the mixing cycle reaches the specified number, the mixing drive 22 can rotate the test consumable 200 to the avoidance state. The test consumable 200 in the avoidance state is set horizontally, which can avoid the test consumable 200 interfering with the flip cover mechanism 3. It can drive the pretreatment flip cover 31 to open the tube hole 11. The mixing drive 22 can drive the test consumable 200 to return to the vertical state. The lifting mechanism 4 can drive the mixing mechanism 2 to rise to the working position, so that the operator can take the processed test consumable 200 through the tube hole 11. In this embodiment, the mixing mechanism 2, the flip-top mechanism 3, and the lifting mechanism 4 can achieve the mixing of the test consumable 200 in the sealed space. There is no need for manual pushing and adding of the test consumable 200, nor is there any need for manual mixing. The mixing state can be accurately detected by the mixing detector 5. Only manual placement and removal of the test consumable 200 are required. This truly realizes high-precision, fully automated sample pretreatment in a sealed space, which improves processing efficiency and ensures processing effect. It can avoid the situation where the sample pretreatment is not in place due to visual identification of the mixing state.

[0046] like Figure 2As shown, the fixing frame 21 includes a hollow tube 211 and a clamping spring 215. The hollow tube 211 has a cavity for accommodating the testing consumable 200. The upper and lower ends of the hollow tube 211 are open, and the side walls have clamping notches 212. The clamping spring 215 is installed on the hollow tube 211 and extends into the cavity through the clamping notches 212. The clamping spring 215 is used to elastically press the testing consumable 200. In this embodiment, the clamping spring 215 is T-shaped. The upper end of the clamping spring 215 is connected to the hollow tube 211, and the lower end is arc-shaped and extends into the cavity through the clamping notches 212 to clamp the testing consumable 200. The structure is simple and the cost is low.

[0047] like Figure 3 As shown, the hollow tube 211 includes a limiting section 213 and a main body section 214. The limiting section 213 is used to limit the detection consumable 200. The main body section 214 is connected to the bottom of the limiting section 213, and a clamping notch 212 is formed in the main body section 214. The cross-sectional dimension of the main body section 214 is larger than that of the limiting section 213. In this embodiment, the limiting section 213 is a hollow column, and the main body section 214 is a hollow cube. By setting the hollow tube 211 into a two-section structure, it is convenient to place the detection consumable 200 while ensuring that the detection consumable 200 can be clamped, which is convenient for operation.

[0048] like Figure 4 As shown, the pretreatment flip cover 31 includes a sealing part 312 and a limiting part 313. The sealing part 312 is used to seal or open the tube hole 11. The limiting part 313 is connected to the bottom of the sealing part 312, and the cross-sectional dimension of the limiting part 313 is larger than that of the sealing part 312. A push rod 311 is disposed at the bottom of the limiting part 313. A top plate 6 with a limiting groove 61 is installed on the top of the outer shell 1. The limiting groove 61 is used to limit the engagement with the limiting part 313. In this embodiment, both the sealing part 312 and the limiting part 313 are columnar, and the sealing part 312, the limiting part 313 and the push rod 311 are coaxially arranged. The pretreatment flip cover 31 in this embodiment adopts a multi-layer design structure, which can form a structural limit between the top plate 6 and the pretreatment flip cover 31, which can prevent the pretreatment flip cover 31 from running off track and further improve the operational stability of the sample pretreatment equipment 100.

[0049] In one embodiment, the flip-top mechanism 3 further includes a flip-top drive member 32 connected to the pre-processing flip-top 31. The flip-top drive member 32 is used to drive the pre-processing flip-top 31 away from or near the tube hole 11. The sample pre-processing device 100 also includes a vertically extending flip-top fixing plate 7. The flip-top drive member 32 is mounted on the flip-top fixing plate 7. The top plate 6 has a positioning groove for the flip-top fixing plate 7 to extend into. In this embodiment, the flip-top fixing plate 7 extends downward from the top plate 6, which facilitates the installation of the flip-top drive member 32. The positioning groove of the top plate 6 facilitates the assembly of the flip-top fixing plate 7, resulting in higher assembly efficiency of the sample pre-processing device 100.

[0050] It should be noted that at least two flip-top fixing plates 7 are sequentially arranged along the length of the outer shell 1, and an installation space is formed between any two adjacent flip-top fixing plates 7. Two flip-top driving components 32 are installed opposite each other within the installation space. The number of mixing mechanism 2, flip-top mechanism 3, and lifting mechanism 4 is the same. The length of the outer shell 1 can be... Figure 1 In the left-right direction, the width direction of the outer shell 1 can be... Figure 1 In the front-back direction, the shell height direction of outer shell 1 can be... Figure 1 The up and down directions within. For example... Figure 2 As shown, in this embodiment, there are two flip-top mechanisms 3, two mixing mechanisms 2, and two lifting mechanisms 4. The flip-top mechanism 3 is located on one side of the main mounting plate 8, and the lifting mechanism 4 and the mixing mechanism 2 are located on the other side of the main mounting plate 8. The two lifting drive members 42 are arranged sequentially in the vertical direction, and the two mixing drive members 22 are arranged spaced apart in the horizontal direction. The two lifting drive members 42 are located between the two mixing drive members 22. The structure is compact and can realize the miniaturization of the sample pretreatment device 100. The flip-top drive members 32 of the two flip-top mechanisms 3 are both arranged within the installation space, which can further improve the structural compactness of the sample pretreatment device 100.

[0051] like Figure 2 As shown, a vertically arranged main mounting plate 8 is also provided inside the processing cavity. A guide rail 81 is provided on the main mounting plate 8, and the mixing mechanism 2 is provided with a guide groove that cooperates with the guide rail 81. The number of guide rails 81 in this embodiment can be set according to actual usage requirements. In this embodiment, the guiding cooperation between the guide rails 81 and the guide groove can further improve the lifting and driving accuracy of the detection consumable 200 on the mixing mechanism 2, and the structure is simple.

[0052] Specifically, the lifting mechanism 4 includes a lifting rack 41 and a lifting drive component 42. The lifting rack 41 is connected to the mixing mechanism 2; the lifting drive component 42 is mounted on the main mounting plate 8, and its output end is provided with a gear that meshes with the lifting rack 41. In this embodiment, the lifting drive component 42 can be a motor. Through the gear and rack transmission structure, the sample pretreatment equipment 100 can be made more compact, the driving stroke more precise, and the lifting mechanism 4 can drive the mixing mechanism 2 to rise and fall to a designated position. Furthermore, assembly is simple and production is convenient.

[0053] In one embodiment, the sample pretreatment device 100 further includes an avoidance detector 9 disposed near the bottom of the outer casing 1, and a first baffle 23 disposed on the mixing mechanism 2. The avoidance detector 9 is used to detect the first baffle 23. In this embodiment, the avoidance detector 9 can be a photoelectric sensor in the prior art; in other embodiments, the avoidance detector 9 can be other detection structures. The mixing mechanism 2 also includes a vertically disposed lifting plate, a guide groove disposed on the lifting plate, and a mixing drive 22 and a lifting rack 41 mounted on the lifting plate. The first baffle 23 can be disposed at the lower end of the lifting plate. In this embodiment, when the lifting mechanism 4 drives the mixing mechanism 2 to descend to the avoidance position, the avoidance detector 9 can detect the first baffle 23 and generate an avoidance completion signal. This avoids mutual interference between components due to incomplete avoidance, improving the operational stability of the sample pretreatment device 100.

[0054] It should be noted that the sample pretreatment device 100 also includes a flip-top detector 10. The flip-top mechanism 3 is provided with a second baffle 33, and the flip-top detector 10 is used to detect the second baffle 33 when it is in the open position. A flip-top connecting rod and a flip-top crank can be sequentially connected between the pretreatment flip-top 31 and the flip-top driving member 32. The flip-top driving member 32 can drive the flip-top connecting rod and the pretreatment flip-top 31 to move through the flip-top crank. One end of the flip-top connecting rod is hinged to the flip-top crank, and the other end is hinged to the pretreatment flip-top 31. The second baffle 33 can be provided on the flip-top crank. When the pretreatment flip-top 31 is in the open position, the second baffle 33 can extend into the flip-top detector 10, so that the flip-top detector 10 can detect the signal that the flip-top is in place. In this embodiment, the flip-top detector 10 can adopt a photoelectric sensor in the prior art. In other embodiments, the flip-top detector 10 can adopt other detection structures. In this embodiment, the flip-top detector 10 detects the opening operation of the flip-top mechanism 3, which can accurately detect the situation when the flip-top is in place, and facilitates the execution of the actions of other mechanisms.

[0055] In the description of this utility model, it should be understood that the terms "first" and "second" are used for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of indicated technical features. Therefore, a feature defined as "first" or "second" may explicitly or implicitly include at least one of that feature. In the description of this utility model, "multiple" means at least two, such as two, three, etc., unless otherwise explicitly specified.

[0056] In this utility model, unless otherwise explicitly specified and limited, the terms "installation," "connection," "joining," and "fixing," etc., should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral part; they can refer to a mechanical connection, an electrical connection, or a connection that allows communication between them; they can refer to a direct connection or an indirect connection through an intermediate medium; they can refer to the internal communication of two components or the interaction between two components, unless otherwise explicitly limited. Those skilled in the art can understand the specific meaning of the above terms in this utility model according to the specific circumstances.

[0057] In the description of this specification, the references to terms such as "one embodiment," "some embodiments," "example," "specific example," or "some examples," etc., indicate that a specific feature, structure, material, or characteristic described in connection with that embodiment or example is included in at least one embodiment or example of the present invention. In this specification, the illustrative expressions of the above terms do not necessarily refer to the same embodiment or example. Furthermore, the specific features, structures, materials, or characteristics described may be combined in any suitable manner in one or more embodiments or examples. Moreover, without contradiction, those skilled in the art can combine and integrate the different embodiments or examples described in this specification, as well as the features of different embodiments or examples.

[0058] Although embodiments of the present invention have been shown and described above, it is understood that the above embodiments are exemplary and should not be construed as limiting the present invention. Those skilled in the art can make changes, modifications, substitutions and variations to the above embodiments within the scope of the present invention.

Claims

1. A sample pre-treatment apparatus for pushing a sample-added detection consumable (200), characterized in that, The sample pretreatment device (100) includes: The outer casing (1) includes a processing cavity with a tube hole (11) for the passage of the testing consumable (200); The mixing mechanism (2) includes a fixed frame (21) and a mixing drive (22) connected to the fixed frame (21). The fixed frame (21) is used to fix the detection consumable (200), and the mixing drive (22) is used to drive the fixed frame (21) to rotate along its own axis and mix the solution in the detection consumable (200). The flip-top mechanism (3) includes a pre-treatment flip-top (31) with a push rod (311) for sealing or opening the tube hole (11); The lifting mechanism (4) is connected to the mixing mechanism (2). The lifting mechanism (4) is used to drive the mixing mechanism (2) to lift and lower, so that the detection consumable (200) abuts against or avoids the push rod (311). A mixing detector (5) is used to detect the number of rotations of the fixture (21).

2. The sample pretreatment apparatus according to claim 1, characterized by The fixing frame (21) includes: A hollow tube (211) is provided with a cavity for accommodating testing consumables (200). The upper and lower ends of the hollow tube (211) are open and the side wall is provided with clamping notches (212). A clamping spring (215) is installed in the hollow tube (211) and extends into the tube cavity through the clamping notch (212). The clamping spring (215) is used to elastically press the detection consumable (200).

3. The sample pretreatment apparatus according to claim 2, characterized by The hollow tube (211) includes: A limiting segment (213) is used to limit the detection consumable (200); The main body segment (214) is connected to the bottom of the limiting segment (213), the clamping notch (212) is opened in the main body segment (214), and the cross-sectional dimension of the main body segment (214) is larger than the cross-sectional dimension of the limiting segment (213).

4. The sample pretreatment apparatus according to claim 1, characterized by The pretreatment flip cover (31) includes: A sealing part (312) is used to seal or open the tube hole (11); A limiting part (313) is connected to the bottom of the sealing part (312). The cross-sectional dimension of the limiting part (313) is larger than that of the sealing part (312). The push rod (311) is disposed at the bottom of the limiting part (313). A top plate (6) with a limiting groove (61) is installed on the top of the outer shell (1). The limiting groove (61) is used to limit and cooperate with the limiting part (313).

5. The sample pretreatment apparatus according to claim 4, characterized by The flip-top mechanism (3) further includes a flip-top drive (32) connected to the pre-processing flip-top (31). The flip-top drive (32) is used to drive the pre-processing flip-top (31) away from or close to the tube hole (11). The sample pre-processing device (100) further includes a vertically extending flip-top fixing plate (7). The flip-top drive (32) is installed on the flip-top fixing plate (7). The top plate (6) has a positioning groove for the flip-top fixing plate (7) to extend into.

6. The sample pretreatment apparatus according to claim 5, characterized by At least two of the flip cover fixing plates (7) are arranged sequentially along the shell length direction of the outer shell (1), and an installation space is formed between any two adjacent flip cover fixing plates (7). Two flip cover driving members (32) are installed opposite each other in the installation space. The number of the mixing mechanism (2), the flip cover mechanism (3) and the lifting mechanism (4) is the same.

7. The sample pretreatment apparatus according to any one of claims 1 to 6, characterized by, The processing cavity is also provided with a vertically arranged main mounting plate (8), and a guide rail (81) is provided on the main mounting plate (8). The mixing mechanism (2) is provided with a guide groove that guides and cooperates with the guide rail (81).

8. The sample pretreatment apparatus according to claim 7, characterized by The lifting mechanism (4) includes: A lifting rack (41) is connected to the mixing mechanism (2); A lifting drive unit (42) is installed on the main mounting plate (8), and the output end of the lifting drive unit (42) is provided with a gear that meshes with the lifting rack (41).

9. The sample pretreatment apparatus according to any one of claims 1 to 6, characterized by, The sample pretreatment device (100) further includes an avoidance detector (9) disposed near the bottom of the outer shell (1), and a first baffle (23) is disposed on the mixing mechanism (2). The avoidance detector (9) is used to detect the first baffle (23).

10. The sample pretreatment apparatus according to any one of claims 1 to 6, characterized by, The sample pretreatment device (100) further includes a flip-top detector (10), and the flip-top mechanism (3) is provided with a second baffle (33). The flip-top detector (10) is used to detect the second baffle (33) when it is in the open position.

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