A device for extracting and purifying a pharmaceutical intermediate

Abstract

The utility model discloses a kind of medical intermediates extraction and purification device, it is related to purification device technical field;And the utility model includes support platform, the top of support platform is fixedly installed with box, the inside of box is equipped with screen frame, screen, activated carbon adsorption net, screen is located in screen frame and activated carbon adsorption net middle, screen frame is located at top, activated carbon adsorption net is located at bottom, activated carbon adsorption net is slidably connected with box, the both sides of screen frame are equipped with connecting block, connecting block is located at the bottom edge of screen frame, the bottom end one side edge of connecting block is fixedly installed with first horizontal plate, first horizontal plate is located in box, the bottom of box is equipped with purification mechanism;The bottom end other side edge of connecting block is fixedly installed with guide rod;The utility model avoids that pharmaceutical intermediate raw materials block screen frame and screen, influence pharmaceutical intermediate raw materials screening, improve work efficiency.

Description

Technical Field

[0001] This utility model relates to the field of purification equipment technology, specifically a pharmaceutical intermediate extraction and purification device. Background Technology

[0002] Publication number "CN219560449U" discloses a pharmaceutical intermediate purification device, including a base, a support rod on the base, and a buffer mechanism, a stirring mechanism, and a dust collection device arranged on the support rod from top to bottom. This utility model uses a sieve to perform preliminary screening of raw materials for traditional Chinese medicine intermediates, followed by further filtration by a filter screen. At the same time, an activated carbon adsorption plate adsorbs impurities and dust, which can improve the purification quality. In addition, the stirring mechanism allows for more thorough stirring, which is beneficial to improving stirring efficiency and thus improving purification efficiency.

[0003] However, in the process of using the above technologies, pharmaceutical intermediate raw materials can easily cause the screens and filters to become clogged, thus affecting the screening of pharmaceutical intermediates and reducing work efficiency. Utility Model Content

[0004] To address the problem that pharmaceutical intermediates easily clog sieves and filters, thus affecting the screening of pharmaceutical intermediates and reducing work efficiency, the purpose of this utility model is to provide a pharmaceutical intermediate extraction and purification device.

[0005] To solve the above technical problems, this utility model adopts the following technical solution: a pharmaceutical intermediate extraction and purification device, including a support platform, a box fixedly installed at the top of the support platform, a sieve frame, a sieve mesh, and an activated carbon adsorption mesh inside the box, the sieve mesh being located between the sieve frame and the activated carbon adsorption mesh, the sieve frame being located at the top, the activated carbon adsorption mesh being located at the bottom, the activated carbon adsorption mesh being slidably connected to the box, connecting blocks being provided on both sides of the sieve frame, the connecting blocks being located at the bottom edge of the sieve frame, a first horizontal plate being fixedly installed at one edge of the bottom end of the connecting block, the first horizontal plate being located in the box, and a purification device being provided at the bottom end of the box. The mechanism includes: a guide rod fixedly installed on the other side edge of the bottom of the connecting block; a fixed plate slidably fitted on the outside of the guide rod; the fixed plate being fixedly connected to the box body; a movable block fixedly installed at the bottom of the guide rod; a rotating shaft passing through the top of the box body; an eccentric wheel fixedly installed on the outside of the rotating shaft for use with the movable block; the rotating shaft being located at the eccentricity of the eccentric wheel; two symmetrically distributed connecting rods fixedly installed at the bottom of the first horizontal plate; a second horizontal plate fixedly installed at the bottom of the connecting rods; the second horizontal plate being slidably connected to the screen via a first trapezoidal block; and through slots for use with the connecting blocks being opened on both sides of the box body.

[0006] Preferably, two stirring shafts rotate through the middle of the housing, and two sleeves are fixedly installed on the outside of the two stirring shafts. The sleeves on the two stirring shafts are staggered with each other. Several evenly distributed curved stirring blades are fixedly installed on the outside of each sleeve. Gears that mesh with each other are fixedly installed at one end of the two stirring shafts. The stirring shafts are located below the rotating shaft.

[0007] Compared with the prior art, the beneficial effects of this utility model are as follows:

[0008] 1. This application avoids the clogging of the sieve frame and sieve by pharmaceutical intermediate raw materials, which affects the screening of pharmaceutical intermediate raw materials and improves work efficiency;

[0009] 2. This application enables the pharmaceutical intermediate raw materials in the box to be mixed more evenly, accelerates the extraction and purification reaction rate, and improves production efficiency. Attached Figure Description

[0010] To more clearly illustrate the technical solutions in the embodiments of this utility model or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of this utility model. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0011] Figure 1 This is a schematic diagram of the structure of this utility model.

[0012] Figure 2 This is a schematic diagram of another aspect of the structure of this utility model.

[0013] Figure 3 This is a schematic diagram of the internal structure of the box in this utility model.

[0014] Figure 4 This is a schematic diagram of the connection structure between the third trapezoidal block and the second trapezoidal groove in this utility model.

[0015] Figure 5 This utility model Figure 4 Enlarged view of point A in the middle.

[0016] Figure 6 This is a schematic diagram of the connection structure between the sleeve and the stirring blade in this utility model.

[0017] Figure 7 This is a schematic diagram of the connection structure between the box body and the first T-shaped block in this utility model.

[0018] In the diagram: 1. Support platform; 10. Through groove; 11. Box body; 12. Screen frame; 13. Screen mesh; 14. Activated carbon adsorption mesh; 15. Connecting block; 16. First horizontal plate; 17. Purification mechanism; 2. Guide rod; 20. Spring; 21. Fixing plate; 22. Moving block; 23. Rotating shaft; 24. Eccentric wheel; 25. Connecting rod; 26. Second horizontal plate; 3. Stirring shaft; 31. Sleeve; 32. Stirring blade; 33. Gear; 4. Second trapezoidal block; 41. First trapezoidal groove; 42. Third trapezoidal block; 43. Second trapezoidal groove; 44. First empty groove; 45. First T-shaped block; 5. Second empty groove; 51. Second T-shaped block; 6. Vertical plate; 61. L-shaped block. Detailed Implementation

[0019] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0020] Example: Figure 1-7 As shown, this utility model provides a pharmaceutical intermediate extraction and purification device, including a support platform 1, a box 11 fixedly installed at the top of the support platform 1, a sieve frame 12, a sieve mesh 13, and an activated carbon adsorption mesh 14 inside the box 11, the sieve mesh 13 being located between the sieve frame 12 and the activated carbon adsorption mesh 14, the sieve frame 12 being located at the top, the activated carbon adsorption mesh 14 being located at the bottom, the activated carbon adsorption mesh 14 being slidably connected to the box 11, connecting blocks 15 being provided on both sides of the sieve frame 12, the connecting blocks 15 being located at the bottom edge of the sieve frame 12, a first horizontal plate 16 being fixedly installed at one edge of the bottom end of the connecting block 15, the first horizontal plate 16 being located in the box 11, and a purification mechanism 17 being provided at the bottom end of the box 11;

[0021] A guide rod 2 is fixedly installed on the other side edge of the bottom end of the connecting block 15. A fixing plate 21 is slidably sleeved on the outside of the guide rod 2. The fixing plate 21 is fixedly connected to the box body 11. A moving block 22 is fixedly installed at the bottom end of the guide rod 2. A rotating shaft 23 is rotatably passed through the top of the box body 11. An eccentric wheel 24 that cooperates with the moving block 22 is fixedly installed on the outside of the rotating shaft 23. The rotating shaft 23 is located at the eccentric part of the eccentric wheel 24. Two symmetrically distributed connecting rods 25 are fixedly installed at the bottom end of the first horizontal plate 16. The bottom of the connecting rod 25... A second horizontal plate 26 is fixedly installed at the end. The second horizontal plate 26 is slidably connected to the screen 13 through a first trapezoidal block. Through slots 10 that cooperate with connecting blocks 15 are opened on both sides of the box body 11. The rotating shaft 23 is driven by a first motor. The first motor is supported by an L-shaped support block, which is fixedly connected to the box body 11. At the same time, the driving end of the first motor is fixedly connected to the rotating shaft 23. Since the purification mechanism 17 has been mentioned in this comparative case, it will not be described here.

[0022] Two stirring shafts 3 rotate through the middle of the housing 11. Two sleeves 31 are fixedly installed on the outside of the two stirring shafts 3. The sleeves 31 on the two stirring shafts 3 are staggered. Several evenly distributed curved stirring blades 32 are fixedly installed on the outside of each sleeve 31. A meshing gear 33 is fixedly installed at one end of the two stirring shafts 3. The stirring shafts 3 are located below the rotating shaft 23. The stirring shafts 3 are driven by a second motor. The second motor is installed on the housing 11 and is opposite to the gear 33. The drive end of the second motor is fixedly connected to the stirring shafts 3.

[0023] The bottom of the box 11 is trapezoidal, which makes it easier to discharge the processed pharmaceutical intermediate raw materials from the outlet of the box 11 into the purification unit 17.

[0024] A spring 20 is fixedly installed at the top of each moving block 22. The spring 20 is fixedly connected to the fixed plate 21. The spring 20 is located outside the guide rod 2. By setting the spring 20, the frequency of the screen frame 12 shaking up and down is increased, and the shaking efficiency of the screen frame 12 is further improved.

[0025] A second trapezoidal block 4 is fixedly installed on both sides of the screen frame 12. A first trapezoidal groove 41 that cooperates with the second trapezoidal block 4 is opened on the inner side of the connecting block 15. Two symmetrically distributed third trapezoidal blocks 42 are fixedly installed at the bottom of the screen frame 12. The third trapezoidal blocks 42 are located at the edge of the screen frame 12. A second trapezoidal groove 43 that cooperates with the third trapezoidal block 42 is opened at the top of the first horizontal plate 16. A first hollow groove 44 is opened through the side of the box body 11 near the gear 33. A first T-shaped block 45 is provided inside the first hollow groove 44. The length and width of the screen frame 12 are smaller than the length and width of the box body 11. The length of the first horizontal plate 16 is the same as the length of the screen frame 12. The lengths of the screen mesh 13 and the second horizontal plate 26 are the same as the length of the box body 11. The length of the second trapezoidal block 4 is longer than the length of the screen frame 12. By setting the second trapezoidal block 4, the first trapezoidal groove 41, the third trapezoidal block 42, and the second T-shaped block 45, the screen frame 12 is equipped with a first trapezoidal groove 43 that cooperates with the third trapezoidal block 42. The trapezoidal groove 43 facilitates the disassembly of the sieve frame 12. The sieve frame 12 is removed from the housing 11, and excess pharmaceutical intermediates are poured out. When the sieve frame 12 needs to be installed inside the housing 11, the first T-shaped block 45 is removed from the housing 11. Then, the bottom end of the third trapezoidal block 42 at the bottom of the sieve frame 12 is aligned with the upper surface of the inner wall of the first empty groove 44, and the outer wall of the second trapezoidal block 4 is aligned with the inner wall of the first empty groove 44. The sieve frame 12 is then pushed into the housing 11. The third trapezoidal block 42 slides on the second trapezoidal groove 43, and the second trapezoidal block 4 slides on the first trapezoidal groove 41. When one side of the second trapezoidal block 4 on the sieve frame 12 is aligned with one side of the inner wall of the housing 11, and the other side of the second trapezoidal block 4 is flush with the other side of the inner wall of the housing 11, it indicates that the sieve frame 12 has been successfully installed in the housing 11, and the center position of the sieve frame 12 corresponds perpendicularly to the center position of the housing 11.

[0026] A second slot 5 is provided through one side of the box 11 near the first T-shaped block 45. The second slot 5 contains a second T-shaped block 51. By providing the second slot 5, it is convenient to remove the screen 13 from the box 11 and clean the screen 13.

[0027] A vertical plate 6 is fixedly installed at the top of the screen 13. The vertical plate 6 is located on the side close to the second empty slot 5. An L-shaped block 61 is fixedly installed on the side of the screen frame 12 close to the vertical plate 6. By setting the vertical plate 6, it is easy to pull the screen 13 out of the box 11. The L-shaped block 61 makes it easy to remove the screen frame 12 from the box 11, thus improving the disassembly efficiency of the screen frame 12 and the screen 13.

[0028] Working principle: In actual use, sealing rings are provided between the first T-shaped block 45 and the first empty slot 44, and between the second T-shaped block 51 and the second empty slot 5 to improve the sealing effect. The mesh size of the sieve frame 12 is larger than that of the sieve 13. During operation, the first motor is started to rotate the shaft 23. Then, the pharmaceutical intermediate raw material is added to the box 11 from the feed port and falls into the sieve frame 12. Then, through the shaking of the sieve frame 12, large impurities are isolated in the sieve frame 12. The raw material falls from the sieve holes in the sieve frame 12 for stirring and dispersing. Then, the raw material is further screened through the sieve 13. The screened material falls onto the activated carbon adsorption net 14 to adsorb impurities and dust, and then enters the purification unit 17 for further processing.

[0029] The shaking process of the sieve frame 12 and sieve screen 13 is driven by the rotation of the rotating shaft 23, which drives the eccentric wheel 24 to rotate. Since the eccentric wheel 24 cooperates with the moving block 22 and the rotating shaft 23 is located at the eccentric part of the eccentric wheel 24, the rotation of the eccentric wheel 24 will cause the moving block 22 to reciprocate in the vertical direction. The moving block 22 drives the guide rod 2 to move up and down in the fixed plate 21. Then, since the sieve frame 12 is connected to the moving block 22 through the second trapezoidal block 4 and connected to the first horizontal plate 16 through the third trapezoidal block 42, and the first horizontal plate 16 and the second horizontal plate 26 are connected by the connecting rod 25, when the connecting block 15 moves up and down, it drives the sieve frame 12 and sieve screen 13 to move up and down, thereby preventing the pharmaceutical intermediate raw materials from clogging the sieve frame 12 and sieve screen 13.

[0030] During the stirring process, the second motor is started, which drives one of the stirring shafts 3 and the corresponding sleeve 31, stirring blade 32, and gear 33 to rotate. Then, through the meshing of the two gears 33, the other stirring shaft 3 and the corresponding sleeve 31, stirring blade 32, and gear 33 move in the opposite direction, thereby stirring and breaking up the pharmaceutical intermediate.

[0031] After the pharmaceutical intermediate is added to the housing 11 from above, it first undergoes preliminary sieving through the sieve frame 12, where large particles are retained. Next, under vibration and stirring, the material passes through the screen 13, where finer impurities are intercepted. The pre-filtered material continues to move downwards, contacting the activated carbon adsorption screen 14, where the activated carbon adsorption screen adsorbs the impurities, achieving further purification. Finally, the pre-treated pharmaceutical intermediate falls into the purification mechanism 17 at the bottom of the housing 11 for more refined purification, resulting in a high-purity pharmaceutical intermediate product.

[0032] Obviously, those skilled in the art can make various modifications and variations to this utility model without departing from its spirit and scope. Therefore, if these modifications and variations fall within the scope of the claims of this utility model and their equivalents, this utility model also intends to include these modifications and variations.

Claims

1. A pharmaceutical intermediate extraction and purification apparatus, comprising a support platform (1), characterized in that: A box (11) is fixedly installed at the top of the support platform (1). Inside the box (11) are a sieve frame (12), a sieve mesh (13), and an activated carbon adsorption mesh (14). The sieve mesh (13) is located between the sieve frame (12) and the activated carbon adsorption mesh (14). The sieve frame (12) is located at the top, and the activated carbon adsorption mesh (14) is located at the bottom. The activated carbon adsorption mesh (14) is slidably connected to the box (11). Connecting blocks (15) are provided on both sides of the sieve frame (12). The connecting blocks (15) are located at the bottom edge of the sieve frame (12). A first horizontal plate (16) is fixedly installed at one edge of the bottom end of the connecting block (15). The first horizontal plate (16) is located in the box (11). A purification mechanism (17) is provided at the bottom end of the box (11). A guide rod (2) is fixedly installed on the other side edge of the bottom end of the connecting block (15). A fixing plate (21) is slidably sleeved on the outside of the guide rod (2). The fixing plate (21) is fixedly connected to the box (11). A moving block (22) is fixedly installed at the bottom end of the guide rod (2). A rotating shaft (23) is rotatably passed through the top of the box (11). An eccentric wheel (24) that cooperates with the moving block (22) is fixedly installed on the outside of the rotating shaft (23). The rotating shaft (23) is located at the eccentric part of the eccentric wheel (24). Two symmetrically distributed connecting rods (25) are fixedly installed at the bottom end of the first horizontal plate (16). A second horizontal plate (26) is fixedly installed at the bottom end of the connecting rod (25). The second horizontal plate (26) is slidably connected to the screen (13) through a first trapezoidal block. Through slots (10) that cooperate with the connecting block (15) are opened through both sides of the box (11).

2. The pharmaceutical intermediate extraction and purification apparatus as described in claim 1, characterized in that, Two stirring shafts (3) rotate through the middle of the housing (11). Two sleeves (31) are fixedly installed on the outside of the two stirring shafts (3). The sleeves (31) on the two stirring shafts (3) are interlaced. Several annularly distributed curved stirring blades (32) are fixedly installed on the outside of each sleeve (31). Gears (33) meshing with each other are fixedly installed at one end of the two stirring shafts (3). The stirring shafts (3) are located below the rotating shaft (23).

3. The pharmaceutical intermediate extraction and purification apparatus as described in claim 1, characterized in that, The bottom of the box (11) is trapezoidal.

4. The pharmaceutical intermediate extraction and purification apparatus as described in claim 1, characterized in that, Each of the moving blocks (22) is fixedly mounted with a spring (20) at its top end. The spring (20) is fixedly connected to the fixed plate (21) and is located outside the guide rod (2).

5. The pharmaceutical intermediate extraction and purification apparatus as described in claim 1, characterized in that, The screen frame (12) is fixedly installed with second trapezoidal blocks (4) on both sides. The inner side of the connecting block (15) is provided with a first trapezoidal groove (41) that cooperates with the second trapezoidal block (4). The bottom end of the screen frame (12) is fixedly installed with two symmetrically distributed third trapezoidal blocks (42). The third trapezoidal blocks (42) are located at the edge of the screen frame (12). The top end of the first horizontal plate (16) is provided with a second trapezoidal groove (43) that cooperates with the third trapezoidal block (42). The side of the box (11) near the gear (33) is provided with a first empty groove (44). The first empty groove (44) is provided with a first T-shaped block (45) inside.

6. The pharmaceutical intermediate extraction and purification apparatus as described in claim 5, characterized in that, The box (11) has a second slot (5) through it on the side near the first T-shaped block (45), and the second slot (5) has a second T-shaped block (51) inside it.

7. The pharmaceutical intermediate extraction and purification apparatus as described in claim 5, characterized in that, The length and width of the sieve frame (12) are both smaller than the length and width of the box body (11). The length of the first horizontal plate (16) is the same as the length of the sieve frame (12). The lengths of the sieve mesh (13) and the second horizontal plate (26) are the same as the length of the box body (11). The length of the second trapezoidal block (4) is longer than the length of the sieve frame (12).

8. The pharmaceutical intermediate extraction and purification apparatus as described in claim 1, characterized in that, A vertical plate (6) is fixedly installed at the top of the screen (13). The vertical plate (6) is located on the side close to the second empty groove (5). An L-shaped block (61) is fixedly installed on the side of the screen frame (12) close to the vertical plate (6).

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