Intestinal tube grafting device

Abstract

This application provides an enterobiota transplantation device, relating to the field of enterobiota transplantation, comprising: a transplantation tube, one end of which is located inside the patient's intestine and is closed with multiple exudation holes on its side wall, and the other end located outside the patient's body; a fixation component for fixing the transplantation tube to the patient's skin; and a sealing component for sealing the externally located end of the transplantation tube. This application improves the convenience and comfort of patients undergoing enterobiota transplantation.

Description

Technical Field

[0001] This application relates to the field of enterocolitis transplantation technology, and more particularly to an enterocolitis transplantation device. Background Technology

[0002] Fecal microbiota transplantation (FMT) involves transplanting functional bacteria from the feces of healthy individuals into the intestines of a patient through specific methods. This aims to regulate intestinal flora imbalance, rebuild a normally functioning intestinal microecological system, and achieve therapeutic or adjunctive therapeutic effects for both intra- and extra-intestinal diseases. FMT has been recommended by clinical guidelines for recurrent or refractory Clostridium difficile infectious diarrhea. Furthermore, it has shown some efficacy in clinical studies for treating inflammatory bowel disease, constipation, irritable bowel syndrome, metabolic syndrome, and other diseases related to intestinal flora dysbiosis, making it a promising new technology.

[0003] Among related technologies, transendoscopic enteral tubing (TET) is a commonly used transplantation method for microbiota transplantation. When there are no contraindications to colonoscopy, a flexible and bendable polymer tube with openings at both ends can be inserted through a colonoscope. The tube can be delivered deep into the colon with the aid of the inner diameter and fixed to the intestinal wall with titanium clips.

[0004] Regarding the aforementioned techniques, because the tube enters the body retrogradely and is left in the intestine through the anus, the existing TET tube is prone to dislodgement with the peristalsis of the large intestine and the patient's defecation movements. Intestinal secretions and excrement can also easily block the tube. In addition, depending on the operation, the TET tube needs to be pulled 5-10cm towards the anus every day to adjust the transplanted microbiota area. Patients experience inconvenience and significant discomfort during the 6-9 day transplantation period with the tube remaining in place, causing considerable inconvenience and discomfort for patients undergoing intestinal microbiota transplantation. Utility Model Content

[0005] To address the issues of poor convenience and comfort for patients undergoing enteromicrobial transplantation, this application provides an enteromicrobial transplantation device.

[0006] The intestinal flora transplantation device provided in this application adopts the following technical solution:

[0007] An intestinal flora transplantation device, comprising:

[0008] The transplant tube has one end located inside the patient's intestine and is sealed with multiple drainage holes on its side wall; the other end is located outside the patient's body.

[0009] Fixation components are used to secure the graft to the patient's skin; and

[0010] The occlusion assembly is used to seal the end of the transplant tube located outside the body.

[0011] Furthermore, the fixing component includes a base pad and a tube patch, wherein an adhesive layer is provided on one side of the base pad, and the tube patch is located on the side of the base pad away from the adhesive layer and is used to attach the transplant tube patch to the base pad.

[0012] Furthermore, the bottom pad is provided with a sponge layer.

[0013] Furthermore, the base pad is in the shape of an inverted triangle.

[0014] Furthermore, the tube is made of breathable adhesive and is provided with multiple tubes spaced apart along the length of the transplant tube.

[0015] Furthermore, the fixing component includes a sleeve, tube wings, and a plug. One end of the sleeve is sealed and inserted into the transplant tube. Two tube wings are provided and are located on both sides of the sleeve. The tube wings are detachably connected to the base pad. The plug is detachably connected to the end of the sleeve away from the transplant tube.

[0016] Furthermore, the tube wing is provided with mounting holes, and the bottom pad is provided with mounting protrusions, the mounting protrusions being interference-fitted with the mounting holes.

[0017] Furthermore, an elastic sealing tube is fixed to the inner wall of the cannula, and the transplant tube is connected to the cannula through the elastic sealing tube.

[0018] Furthermore, the transplant tube is provided with an elastic flap inside the exudation hole, and a limiting ring is attached to the side of the elastic flap near the inside of the transplant tube.

[0019] Furthermore, the end of the transplant tube located inside the intestine is designed with a rounded end.

[0020] In summary, this application includes at least one of the following beneficial technical effects:

[0021] 1. By setting up a transplant tube and fixing one end of the transplant tube outside the body to the patient's skin with a fixing component, and sealing the transplant tube with a sealing component, the transplant tube is stably fixed to the patient for 6-9 days. The sealing component also reduces the possibility of fluid from the transplant tube leaking out and contaminating the patient's clothing, thereby effectively improving the convenience and comfort of patients undergoing intestinal microbiota transplantation.

[0022] 2. By setting an inverted triangular base pad, the base pad can conform to the contour of the human buttock and tail. In addition, the base pad is equipped with an adhesive layer and a sponge layer, so that the base pad can be stably attached to the skin near the patient's buttock and tail. The tube patch at the location can firmly fix the transplant tube, further improving the patient's comfort.

[0023] 3. By setting a sleeve, tube wings and a plug, the transplant tube can be inserted into the sleeve, and the sleeve can be fixed to the base pad by the tube wings, reducing the possibility of the transplant tube end displacement and improving the stability of the device during use.

[0024] 4. By setting an elastic flap in the permeation space and attaching a limiting ring to the side of the elastic flap near the inside of the transplant tube, the elastic flap can only expand outward in one direction, allowing the bacterial fluid to seep out from the transplant tube, while also reducing the possibility of intestinal fluid flowing into the transplant tube. Attached Figure Description

[0025] To more clearly illustrate the technical solutions in this invention or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are some embodiments of this invention. For those skilled in the art, other drawings can be obtained from these drawings without creative effort.

[0026] Figure 1 This is a schematic diagram of the overall structure of an embodiment of this application.

[0027] Figure 2 This is a schematic diagram of the structure of the fixing component and the sealing component according to an embodiment of this application.

[0028] Figure 3 This is a schematic diagram of the structure of the transplant tube located at one end in the body according to an embodiment of this application.

[0029] Reference numerals: 1. Transplantation tube; 11. Exudation hole; 12. Round head; 2. Fixation component; 21. Base pad; 211. Protrusion; 22. Tube patch; 3. Sealing component; 31. Sleeve; 32. Tube wing; 321. Mounting hole; 33. Plug; 4. Elastic flap; 5. Limiting ring. Detailed Implementation

[0030] To make the objectives, technical solutions, and advantages of this invention clearer, the technical solutions of this invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some, not all, of the embodiments of this invention. All other embodiments obtained by those skilled in the art based on the embodiments of this invention without creative effort are within the scope of protection of this invention.

[0031] This application discloses an intestinal flora transplantation device. Please refer to... Figure 1 The intestinal flora transplantation device includes a transplantation tube 1, a fixation component 2, and a sealing component 3. The transplantation tube 1 is a flexible tube with a certain degree of rigidity, allowing it to be inserted retrogradely into the intestine through the patient's anus. To improve comfort during insertion, the end of the transplantation tube 1 located inside the body is designed with a rounded head 12 (e.g., Figure 3 As shown, the end of the transplant tube 1 that penetrates into the intestine is sealed, and multiple exudation holes 11 are provided on the side wall near this end to facilitate the drainage of the bacterial solution to be transplanted into the patient's intestine through the exudation holes 11, thereby realizing the transplantation of intestinal bacteria. The other end of the transplant tube 1 is located outside the patient's body. The fixation component 2 is located outside the patient's body and is used to fix the transplant tube 1 to the patient's skin. The sealing component 3 is used to seal the end of the transplant tube 1 located outside the body.

[0032] During intestinal microbiota transplantation, the end of the transplantation tube 1 with a permeation hole is inserted into the intestine through the anus, while the other end of the transplantation tube 1 is located outside the patient's body and fixed to the patient's skin by the fixation component 2, thus securing the transplantation tube 1 and preventing it from falling out. The sealing component 3 seals the transplantation tube 1, effectively preventing the liquid inside the transplantation tube 1 from flowing out and contaminating the patient's clothing. This allows the patient to live a normal life during intestinal microbiota transplantation, improving the convenience and comfort of the patient's life.

[0033] Please refer to Figure 1 and Figure 2 The fixing component 2 includes a base pad 21 and a tube patch 22. One side of the base pad 21 is provided with an adhesive layer. The adhesive layer can be made of medical pressure-sensitive adhesive with good breathability and low irritation. The tube patch 22 is made of breathable adhesive. By wrapping the two adhesive parts of the tube patch 22 around the transplant tube 1, the transplant tube 1 is fixed in a circumferential manner.

[0034] To further improve patient comfort, a sponge layer is provided in the base pad 21, so that when the transplant tube 1 is fixed on the base pad 21, the base pad 21 can be concave to avoid the transplant tube 1 directly pressing on the skin and causing discomfort. Furthermore, the concave shape of the transplant tube 1 on the base pad 21 can further improve the stability of the transplant tube 1 fixation.

[0035] Since the transplant tube 1 is located outside the body, starting from the anus, the base pad 21 is designed in an inverted triangular shape to adapt to the body's surface structure, such as... Figure 2 As shown (for ease of demonstrating the shape of the base pad 21), Figure 2 (Illustration of separating the base pad 21 from the tube patch 22 and the fixing component 2) and fitting the base pad 21 to fit the buttocks and tail area, so that the base pad 21 can fit the patient's skin well, allowing the patient to dress and walk normally, further improving the convenience and comfort of life for patients with intestinal microbiota transplantation.

[0036] To further improve the stability of the transplant tube 1 fixation, multiple tube patches 22 are spaced apart along the length of the transplant tube 1, thereby increasing the contact area between the tube patch 22 and the transplant tube 1, making the base pad 21 and the tube patch 22 resemble a scorpion, thus greatly improving the stability of the transplant tube 1 fixation.

[0037] The fixing component 2 includes a sleeve 31, tube wings 32, and a plug 33. One end of the sleeve 31 is sealed and inserted into the transplant tube 1. Two tube wings 32 are respectively glued and fixed to both sides of the sleeve 31, so that the tube wings 32 and the sleeve 31 form a butterfly shape. By detachably connecting the tube wings 32 to the base pad 21, the sleeve 31 can be detachably placed on the base pad 21. The plug 33 is made of rubber. By inserting the plug 33 into the end of the sleeve 31 away from the transplant tube 1, the transplant tube 1 can be sealed. To reduce the possibility of the plug 33 being lost, an anti-drop rope can be connected between the plug 33 and the sleeve 31.

[0038] When it is necessary to pull the transplant tube 1 to change the location of the intestinal flora transplantation, remove the tube wing 32 from the base pad 21, separate the sleeve 31 from the transplant tube 1, pull the transplant tube 1 15-10cm, and cut the transplant tube 1 to keep the end of the transplant tube 1 as inconvenient as possible. Then insert the transplant tube 1 into the sleeve 31 and fix the sleeve 31 to the base pad 21 with the tube wing 32 to complete the migration of the transplant tube 1. After the migration of the transplant tube 1 is completed, open the plug 33 and inject intestinal flora solution into the transplant tube 1 to realize the intestinal flora transplantation at the new location. After the injection is completed, seal the sleeve 31 with the plug 33 to facilitate the daily adjustment of the transplanted flora area.

[0039] The tube wing 32 has a mounting hole 321, and the base pad 21 has a protrusion 211. By interfering with the mounting hole 321, the tube wing 32 and the base pad 21 are snapped together. As an alternative embodiment, an adhesive layer can be provided on the side of the tube wing 32 near the base pad 21, and it can be fixed to the base pad 21 by adhesive bonding. Alternatively, the protrusion 211 can be set as a threaded post, and the tube wing 32 can be locked to the base pad 21 with a nut.

[0040] In order to achieve better sealing between the cannula 31 and the transplant tube 1, the inner diameter of the cannula 31 is larger than the outer diameter of the transplant tube 1. An elastic sealing tube is bonded and fixed to the inner wall of the cannula 31. The transplant tube 1 is inserted into the elastic sealing tube, which can achieve sealing between the transplant tube 1 and the cannula 31, and at the same time improve the stability of the transplant tube 1 inside the cannula 31.

[0041] Please refer to Figure 3Multiple exudation holes 11 are spaced apart along the length of the transplant tube 1, and these holes are staggered to reduce the possibility of bacterial leakage and the resulting push force causing the transplant tube 1 to shift. To effectively prevent intestinal fluid from flowing into the transplant tube 1 and contaminating it, an elastic flap 4 is provided inside the exudation hole 11 of the transplant tube 1. Under the pressure of the bacterial fluid, the elastic flap 4 can open, allowing the bacterial fluid to pass through the exudation hole 11 into the patient's intestine. A limiting ring 5 is provided on the side of the elastic flap 4 closest to the inside of the transplant tube 1. The limiting ring 5 is fitted to the elastic flap 4 and can effectively prevent the elastic flap 4 from opening into the transplant tube 1, thus reducing the possibility of feces entering the transplant tube 1 and causing blockage.

[0042] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention, and not to limit them; although the present invention has been described in detail with reference to the foregoing embodiments, those skilled in the art should understand that modifications can still be made to the technical solutions described in the foregoing embodiments, or equivalent substitutions can be made to some of the technical features; and these modifications or substitutions do not cause the essence of the corresponding technical solutions to deviate from the spirit and scope of the technical solutions of the embodiments of the present invention.

Claims

1. A device for transplanting enterocolitis bacteria, characterized in that, include: The transplant tube has one end located inside the patient's intestine and is sealed with multiple drainage holes on its side wall; the other end is located outside the patient's body. Fixation components are used to secure the graft to the patient's skin; as well as The occlusion assembly is used to seal the end of the transplant tube located outside the body.

2. The intestinal flora transplantation device according to claim 1, characterized in that, The fixation assembly includes a base pad and a tube patch. An adhesive layer is provided on one side of the base pad, and the tube patch is located on the side of the base pad away from the adhesive layer and is used to attach the transplant tube patch to the base pad.

3. The intestinal flora transplantation device according to claim 2, characterized in that, The base pad has a sponge layer.

4. The intestinal flora transplantation device according to claim 3, characterized in that, The base pad has an inverted triangular shape.

5. The intestinal flora transplantation device according to claim 2, characterized in that, The tube is fitted with a breathable adhesive and multiple tubes are spaced apart along the length of the transplant tube.

6. The intestinal flora transplantation device according to claim 2, characterized in that, The fixing assembly includes a sleeve, tube wings, and a plug. One end of the sleeve is sealed and inserted into the transplant tube. Two tube wings are provided and are located on both sides of the sleeve. The tube wings are detachably connected to the base pad. The plug is detachably connected to the end of the sleeve away from the transplant tube.

7. The intestinal flora transplantation device according to claim 6, characterized in that, The tube wing is provided with mounting holes, and the base pad is provided with mounting protrusions, the mounting protrusions being interference-fitted with the mounting holes.

8. The intestinal flora transplantation device according to claim 7, characterized in that, An elastic sealing tube is fixed to the inner wall of the cannula, and the transplant tube is connected to the cannula through the elastic sealing tube.

9. The intestinal flora transplantation device according to claim 1, characterized in that, The transplant tube has an elastic flap inside the exudation hole, and a limiting ring is attached to the side of the elastic flap near the inside of the transplant tube.

10. The intestinal flora transplantation device according to claim 9, characterized in that, The end of the transplant tube located inside the intestine is designed with a rounded end.

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