An adjustable chromatography column

Abstract

This utility model belongs to the field of chromatography column technology, specifically an adjustable chromatography column, including an outer column tube; an inner column tube slidably fitted to the inner wall of the outer column tube; an upper sieve plate installed at the top of the inner column tube; a lower sieve plate installed at the bottom of the outer column tube; a feed pipe at the top of the inner column tube; a discharge pipe at the bottom of the outer column tube; a connecting assembly fixedly connected to the outer wall of the outer column tube; an observation assembly provided on the side wall of the outer column tube; the connecting assembly includes fixing lugs; the fixing lugs are evenly distributed on the outer wall of the outer column tube; a mounting seat is evenly distributed on the top of the upper sieve plate; the connecting assembly allows for the connection and adjustment of the outer and inner column tubes, facilitating the adjustment of the chromatography column capacity according to usage requirements; the observation assembly allows for the observation of the material inside the chromatography column, enhancing the adjustability and portability of the adjustable chromatography column.

Description

Technical Field

[0001] This invention belongs to the field of chromatography column technology, specifically an adjustable chromatography column. Background Technology

[0002] A chromatography column is one of the most important devices in chromatography technology. Its core function is to separate, purify, or analyze the components in a mixture through the relative movement of the stationary phase and the mobile phase. It separates substances based on differences in molecular size, with larger molecules eluding first and smaller molecules eluding later.

[0003] The interior of a chromatography column is filled with a stationary phase. When the mobile phase containing the components to be separated passes through the stationary phase, the components move at different speeds within the column due to differences in the forces they interact with the stationary phase, such as adsorption capacity, charge interaction, molecular size exclusion, and partition coefficient, thereby achieving separation.

[0004] After prolonged use, it was found that traditional chromatography columns have a fixed length and capacity when they are manufactured. When dealing with mixtures of different specifications, different types of chromatography columns need to be replaced, which is not only time-consuming and laborious but also difficult to adjust.

[0005] Therefore, this utility model provides an adjustable chromatography column. Utility Model Content

[0006] In order to overcome the shortcomings of the prior art, at least one technical problem raised in the background art is solved.

[0007] The technical solution adopted by this utility model to solve its technical problem is as follows: An adjustable chromatography column of this utility model includes an outer column tube; an inner column tube is slidably fitted to the inner wall of the outer column tube; an upper sieve plate is installed at the top of the inner column tube; a lower sieve plate is installed at the bottom of the outer column tube; an inlet pipe is provided at the top of the inner column tube; an outlet pipe is provided at the bottom of the outer column tube; a connecting component is fixedly connected to the outer wall of the outer column tube; and an observation component is provided on the side wall of the outer column tube. Through the above structure and the setting of the connecting component, the outer column tube and the inner column tube can be connected and adjusted, facilitating the adjustment of the chromatography column capacity according to usage requirements. The setting of the observation component allows for observation of the material inside the chromatography column, enhancing the adjustability and portability of the adjustable chromatography column.

[0008] Preferably, the connecting component includes a fixing lug; the fixing lug is evenly distributed on the outer wall of the outer column tube; a mounting seat is fixedly connected to the top of the upper sieve plate; the mounting seats are evenly distributed on the top of the upper sieve plate; through the above structure, the fixing lug and mounting seat can be connected to the adjustment device, which facilitates the control and adjustment of the outer and inner column tubes, and further enhances the adjustment and connection effect of the adjustable chromatography column.

[0009] Preferably, the observation component includes a first observation window; the inner column tube sidewall is provided with a second observation window; through the above structure, the setting of the first and second observation windows facilitates the observation of the materials inside the outer and inner column tubes, further enhancing the observation effect of the adjustable chromatography column.

[0010] Preferably, the top of the inner wall of the outer column tube is provided with a docking groove; the inner column tube is fixedly connected to a docking plate; the inner wall of the docking groove is slidably fitted with a docking plate; through the above structure, the docking groove and docking plate can be fully deployed and sealed between the outer column tube and the inner column tube to avoid material leakage and further enhance the docking sealing effect of the adjustable chromatography column.

[0011] Preferably, the side wall of the discharge pipe is provided with an installation groove; a filter screen is slidably fitted on the inner side wall of the installation groove; through the above structure, the installation groove and the filter screen can filter the material discharged from the discharge pipe, further enhancing the discharge screening effect of the adjustable chromatography column.

[0012] Preferably, a control plate is fixedly connected to the outer wall of the filter screen; a pull frame is fixedly connected to the side wall of the control plate; through the above structure, the setting of the control plate and the pull frame can make the replacement of the filter screen more convenient, and further enhance the portability of maintenance and replacement of the adjustable chromatography column.

[0013] Preferably, the control panel sidewall is fitted with an anti-slip pad; through the above structure, the anti-slip pad can increase the friction on the surface of the pull frame, avoid slippage, and further enhance the anti-slip effect of the adjustable chromatography column replacement and maintenance.

[0014] The beneficial effects of this utility model are as follows:

[0015] 1. The adjustable chromatography column of this utility model, through the setting of the connecting component, can connect and adjust the external column tube and the internal column tube, so as to facilitate the adjustment of the capacity of the chromatography column according to the usage requirements. Through the setting of the observation component, the material inside the chromatography column can be observed, thus enhancing the adjustment and portability of the adjustable chromatography column.

[0016] 2. The adjustable chromatography column of this utility model can be connected to the adjustment equipment through the setting of the fixed lug and the mounting base, which facilitates the control and adjustment of the external column tube and the internal column tube, and further enhances the adjustment and connection effect of the adjustable chromatography column. Attached Figure Description

[0017] The present invention will be further described below with reference to the accompanying drawings.

[0018] Figure 1 This is a perspective view of the present invention;

[0019] Figure 2 This is a schematic diagram of the internal column tube structure in this utility model;

[0020] Figure 3 This is a schematic diagram of the docking groove structure in this utility model;

[0021] Figure 4 This is a schematic diagram of the filter screen structure in this utility model.

[0022] In the diagram: 1. External column tube; 11. Internal column tube; 12. Upper screen plate; 13. Feed pipe; 14. Discharge pipe; 15. Lower screen plate; 2. Fixed hanging lug; 21. Mounting base; 3. First observation window; 31. Second observation window; 4. Connecting groove; 41. Connecting plate; 5. Mounting groove; 51. Filter screen; 6. Control panel; 61. Pulling frame; 7. Anti-slip pad. Detailed Implementation

[0023] To make the technical means, creative features, objectives and effects of this utility model easier to understand, the present utility model will be further described below in conjunction with specific embodiments.

[0024] like Figures 1 to 3 As shown in the figure, an adjustable chromatography column according to an embodiment of the present invention includes an outer column tube 1; an inner column tube 11 is slidably fitted to the inner side wall of the outer column tube 1; an upper sieve plate 12 is installed on the top of the inner column tube 11; a lower sieve plate 15 is installed on the bottom of the outer column tube 1; a feed pipe 13 is provided at the top of the inner column tube 11; a discharge pipe 14 is provided at the bottom of the outer column tube 1; a connecting assembly is fixedly connected to the outer side wall of the outer column tube 1; and an observation assembly is provided on the side wall of the outer column tube 1. During operation, the capacity of the chromatography column can be adjusted as needed through the outer column tube 1 and the inner column tube 11, and the feed pipe 13 can be used to discharge the material. The material is fed into the chromatography column, and the processed material can be discharged through the discharge pipe 14. The external column tube 1 and the internal column tube 11 can be easily connected and adjusted by the connecting component through an external adjustment device. The material inside the chromatography column can be observed by observing the setting of the observation component. The connection component allows for the connection and adjustment of the external column tube 1 and the internal column tube 11, making it convenient to adjust the capacity of the chromatography column according to the usage requirements. The observation component also enhances the portability of the adjustable chromatography column.

[0025] like Figures 1 to 3As shown, the connecting assembly includes a fixing lug 2; the fixing lug 2 is evenly distributed on the outer wall of the outer column tube 1; a mounting base 21 is fixedly connected to the top of the upper sieve plate 12; the mounting base 21 is evenly distributed on the top of the upper sieve plate 12; during operation, the fixing lug 2 and the mounting base 21 can stably connect the outer column tube 1 and the inner column tube 11, facilitating the control and adjustment of the outer column tube 1 and the inner column tube 11, and facilitating the capacity adjustment of the chromatography column; the fixing lug 2 and the mounting base 21 can be connected to the adjustment device, facilitating the control and adjustment of the outer column tube 1 and the inner column tube 11, further enhancing the adjustment and connection effect of the adjustable chromatography column.

[0026] like Figures 1 to 3 As shown, the observation assembly includes a first observation window 3; a second observation window 31 is provided on the side wall of the inner column tube 11; during operation, the materials inside the outer column tube 1 and the inner column tube 11 can be observed through the first observation window 3 and the second observation window 31, which facilitates the volume observation of the processed materials; the setting of the first observation window 3 and the second observation window 31 facilitates the observation of the materials inside the outer column tube 1 and the inner column tube 11, further enhancing the observation effect of the adjustable chromatography column.

[0027] like Figures 1 to 3 As shown, the top of the inner wall of the outer column tube 1 is provided with a docking groove 4; the inner column tube 11 is fixedly connected to the side wall with a docking plate 41; the inner wall of the docking groove 4 is slidably fitted with the docking plate 41; during operation, the docking groove 4 and the docking plate 41 can be used to achieve docking and sealing when the outer column tube 1 and the inner column tube 11 are stretched; the docking groove 4 and the docking plate 41 can be used to achieve docking and sealing when the outer column tube 1 and the inner column tube 11 are fully extended, avoiding material leakage and further enhancing the docking and sealing effect of the adjustable chromatography column.

[0028] like Figures 1 to 4 As shown, an installation groove 5 is provided on the side wall of the discharge pipe 14; a filter screen 51 is slidably fitted on the inner side wall of the installation groove 5; during operation, the material discharged from the discharge pipe 14 can be filtered through the installation groove 5 and the filter screen 51 to prevent unqualified materials from being discharged; the installation groove 5 and the filter screen 51 can filter the material discharged from the discharge pipe 14, further enhancing the discharge screening effect of the adjustable chromatography column.

[0029] like Figures 3 to 4 As shown, a control plate 6 is fixedly connected to the outer wall of the filter screen 51; a pull frame 61 is fixedly connected to the side wall of the control plate 6; during operation, the filter screen 51 can be easily replaced through the control plate 6 and the pull frame 61, reducing the tedious operation of maintenance; the setting of the control plate 6 and the pull frame 61 makes the replacement of the filter screen 51 more convenient, further enhancing the portability of maintenance and replacement of the adjustable chromatography column.

[0030] like Figure 4As shown, the control plate 6 has anti-slip pads 7 on its side walls. During operation, the anti-slip pads 7 increase the friction of the control plate 6 side walls, making it less likely for the pull frame 61 to fall off. The anti-slip pads 7 also increase the friction of the pull frame 61 surface, preventing slippage and further enhancing the anti-slip effect during the replacement and maintenance of the adjustable chromatography column.

[0031] During operation, the capacity of the chromatography column can be adjusted as needed via the external column tube 1 and the internal column tube 11. Material is delivered into the column via the feed pipe 13, and the processed material is discharged via the discharge pipe 14. The connecting assembly allows for convenient connection and adjustment of the external column tube 1 and the internal column tube 11 via an external adjustment device. The material inside the chromatography column can be observed by observing the settings of the observation assembly. The fixing lug 2 and the mounting base 21 ensure a stable connection between the external column tube 1 and the internal column tube 11, facilitating control and adjustment of the column and enabling convenient capacity adjustment. The first observation window 3 and the second observation window 31 allow observation of the materials inside the outer column tube 1 and the inner column tube 11, facilitating volume observation of the processed materials. The docking groove 4 and the docking plate 41 enable docking and sealing when the outer column tube 1 and the inner column tube 11 are stretched. The installation groove 5 and the filter screen 51 allow filtration of the materials discharged from the discharge pipe 14, preventing the discharge of unqualified materials. The control plate 6 and the pull frame 61 facilitate the replacement of the filter screen 51, reducing the tedious operation of maintenance. The anti-slip pad 7 increases the friction of the side wall of the control plate 6, making it less likely for the pull frame 61 to fall off during use.

[0032] The foregoing has shown and described the basic principles, main features, and advantages of this utility model. Those skilled in the art should understand that this utility model is not limited to the above embodiments. The embodiments and descriptions in the specification are merely illustrative of the principles of this utility model. Various changes and modifications can be made to this utility model without departing from its spirit and scope, and all such changes and modifications fall within the scope of the claimed utility model. The scope of protection of this utility model is defined by the appended claims and their equivalents.

Claims

1. An adjustable chromatography column, comprising an outer column tube (1); characterized in that: The inner wall of the outer column tube (1) is slidably fitted with an inner column tube (11); an upper screen plate (12) is installed on the top of the inner column tube (11); a lower screen plate (15) is installed on the bottom of the outer column tube (1); an inlet pipe (13) is provided on the top of the inner column tube (11); an outlet pipe (14) is provided on the bottom of the outer column tube (1); a connecting component is fixedly connected to the outer wall of the outer column tube (1); and an observation component is provided on the side wall of the outer column tube (1).

2. The adjustable chromatography column according to claim 1, characterized in that: The connecting assembly includes a fixed hanging ear (2); the fixed hanging ear (2) is evenly distributed on the outer side wall of the outer column tube (1); the top of the upper screen plate (12) is fixed with a mounting seat (21); the mounting seat (21) is evenly distributed on the top of the upper screen plate (12).

3. An adjustable chromatography column according to claim 1, characterized in that: The observation assembly includes a first observation window (3); the inner column tube (11) has a second observation window (31) on its side wall.

4. An adjustable chromatography column according to claim 1, characterized in that: The top of the inner wall of the outer column tube (1) is provided with a docking groove (4); the inner column tube (11) is fixedly connected to a docking plate (41); the inner wall of the docking groove (4) is slidably fitted with a docking plate (41).

5. An adjustable chromatography column according to claim 1, characterized in that: The discharge pipe (14) has an installation groove (5) on its side wall; a filter screen (51) is slidably fitted on the inner side wall of the installation groove (5).

6. An adjustable chromatography column according to claim 5, characterized in that: A control plate (6) is fixed to the outer wall of the filter screen (51); a pull frame (61) is fixed to the side wall of the control plate (6).

7. An adjustable chromatography column according to claim 6, characterized in that: The control panel (6) has anti-slip pads (7) on its side walls.

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