An antigen inactivation tank device for vaccine production
By introducing heating coils, stirring rods, and a steam permeation system into the antigen inactivation tank equipment, the problem of cleaning dead spots in existing equipment has been solved, achieving efficient cleaning and safety of the inactivation tank.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- SHANGHAI GAOJI BIOENG
- Filing Date
- 2025-06-09
- Publication Date
- 2026-06-02
AI Technical Summary
Existing antigen inactivation equipment is difficult to clean efficiently after use, leaving cleaning dead spots and resulting in low work efficiency.
An antigen inactivation tank device was designed, which includes a heating coil, a stirring rod, a steam delivery system and a booster pump. The solution is heated by the heating coil, the stirring rod is stirred evenly, the steam penetrates into the fine gaps, the principle of thermal expansion and contraction is used to weaken the adhesion of dirt, and the details are cleaned by the spray gun.
It achieves efficient cleaning of the inside of the inactivation tank, improves cleaning efficiency, reduces cleaning dead spots, and ensures the safety and effectiveness of the equipment.
Smart Images

Figure CN224313497U_ABST
Abstract
Description
Technical Field
[0001] This utility model relates to the field of vaccine production technology, and in particular to an antigen inactivation tank device for vaccine production. Background Technology
[0002] In the field of vaccine production, antigen inactivation is a key step in ensuring the safety and effectiveness of vaccines. Antigen inactivation aims to destroy the infectivity of pathogens while preserving their immunogenicity, enabling the human immune system to recognize and generate an immune response.
[0003] Existing antigen inactivation equipment requires timely cleaning after installation and use. This typically involves workers using hand-held soft brushes to clean the inside of the equipment, which can easily lead to blind spots and low work efficiency, negatively impacting user experience. To address the shortcomings of existing technology, we propose an antigen inactivation tank for vaccine production. Utility Model Content
[0004] The main objective of this invention is to provide an antigen inactivation tank device for vaccine production, which can effectively solve the problems in the background art.
[0005] To achieve the above objectives, the technical solution adopted by this utility model is as follows:
[0006] An antigen inactivation tank device for vaccine production includes a base, a water storage tank located on the upper right side of the base, an inlet pipe and a drain pipe located on the lower right side of the water storage tank, a filter screen inside the inlet pipe, multiple heating tubes inside the water storage tank, an inactivation tank body located on the upper left side of the base, a steam delivery pipe between the water storage tank and the inactivation tank body, a booster pump located above the steam delivery pipe, a diverter pipe located on the outer side of the front end of the steam delivery pipe, a connecting hose located inside the diverter pipe, a spray gun located at the other end of the connecting hose, two sets of spring clips located on the outer surface of the front end of the water storage tank, and a cable management rack located on the left side of the water storage tank.
[0007] Preferably, the inactivation tank body has a double-layer structure. Multiple heating coils are installed inside the inactivation tank body. A discharge port is located at the lower front of the inactivation tank body. A column is located at the rear of the inactivation tank body. A first motor is installed at the upper end of the column. A transmission rod is installed inside the column, and the upper end of the transmission rod is connected to the rotor end of the first motor. A mounting bracket is located at the front end of the column. A sealing cover is located below the mounting bracket. A second motor is located at the middle of the upper outer surface of the sealing cover. A stirring rod is located below the sealing cover, and the upper end of the stirring rod is connected to the rotor end of the second motor.
[0008] Preferably, the water storage tank is fixedly installed on the upper right side of the base, the heating tube is detachably installed inside the water storage tank, the water inlet pipe and the sewage outlet pipe are welded to the bottom right side of the water storage tank, and the filter screen is detachably installed inside the water inlet pipe.
[0009] Preferably, the two ends of the steam delivery pipeline are detachably connected to the inactivation tank body and the water storage tank, respectively. The booster pump is detachably installed above the steam delivery pipeline. The diversion pipe is fixedly welded to the outer front end of the steam delivery pipeline. The spray gun is detachably connected to the diversion pipe through a connecting hose. The spring clip is fixedly installed at the front end of the water storage tank. The cable management rack is fixedly installed on the left side of the water storage tank by welding.
[0010] Preferably, the column is fixedly mounted on the top of the base by welding, the first motor is detachably mounted on the upper end of the column, the upper end of the transmission rod is detachably connected to the rotor end of the first motor, and the transmission rod is threadedly connected to the mounting bracket.
[0011] Preferably, the sealing cover is fixedly disposed below the mounting bracket, the second motor is detachably mounted on the upper outer surface of the sealing cover, and the upper end of the stirring rod is detachably connected to the rotor end of the second motor.
[0012] Compared with the prior art, the present invention has the following beneficial effects:
[0013] In this invention, a heating coil is used to heat the solution inside the inactivation tank. Simultaneously, a second motor controls the rotation of a stirring rod to stir the solution, ensuring even heating. A first motor controls the rotation of a transmission rod, making it easier for workers to lift the sealing cap and facilitate subsequent cleaning of the inside of the inactivation tank.
[0014] In this invention, a heating pipe heats the water inside the storage tank to generate steam. A booster pump then delivers the steam into the interior of the inactivation canister. The steam has excellent permeability, penetrating deep into the tiny gaps and pores inside the canister. The high-temperature steam causes the dirt to expand due to heat, while the inner wall of the canister remains relatively unchanged. This difference in thermal expansion and contraction creates tiny gaps between the dirt and the inner wall of the canister, weakening the adhesion between the dirt and the surface and making it easier to remove. Attached Figure Description
[0015] Figure 1 This is a schematic diagram of the overall structure of this utility model;
[0016] Figure 2 This is a schematic diagram of the connection structure between the stirring rod and the second motor of this utility model;
[0017] Figure 3 This is a schematic diagram of the connection structure between the spray gun and the steam conveying pipeline of this utility model;
[0018] Figure 4 This is a schematic diagram of the internal structure of the water storage tank of this utility model.
[0019] In the diagram: 1. Base; 2. Inactivation tank body; 3. Sealing cap; 4. Column; 5. First motor; 6. Transmission rod; 7. Mounting bracket; 8. Second motor; 9. Stirring rod; 10. Water tank; 11. Water inlet pipe; 12. Sewage outlet pipe; 13. Steam delivery pipe; 14. Booster pump; 15. Diverter pipe; 16. Spray gun; 17. Connecting hose; 18. Cable management rack; 19. Spring clip; 20. Heating tube; 21. Filter screen; 22. Discharge port; 23. Heating coil. Detailed Implementation
[0020] To make the technical means, creative features, objectives and effects of this utility model easier to understand, the present utility model will be further described below in conjunction with specific embodiments.
[0021] Example 1, as Figures 1-4 As shown, an antigen inactivation tank device for vaccine production includes a base 1. Workers place the vaccine into the inactivation tank body 2, start the first motor 5, and control the transmission rod 6 to rotate, causing the sealing cover 3 to move downwards. This, combined with the sealing strip below the sealing cover 3, seals the inactivation tank body 2. Then, under the action of the existing heating coil 23, the vaccine inside the inactivation tank body 2 is heated. Under high temperature, the proteins inside the antigen denature, and the structure of the nucleic acid is destroyed, thereby rendering the virus infective and pathogenic, achieving the purpose of inactivation. Under the action of the second motor 8, the stirring rod 9 rotates, stirring the vaccine inside the inactivation tank body 2 to ensure uniform heating, and then it is discharged from the discharge port 22 at the bottom.
[0022] Example 2, as Figures 1-4As shown, an antigen inactivation tank device for vaccine production, when the staff needs to clean the inside of the inactivation tank body 2, first ensure that the sealing cover 3 seals the inactivation tank body 2, then tighten the control valve above the discharge port 22, start the existing steam generator above the water storage tank 10, and power the heating pipe 20 to make the water inside the water storage tank 10 boil and convert it into steam. Under the action of the booster pump 14, the steam entering the booster pump 14 is pushed by the impeller. The impeller does work on the steam, increasing the kinetic energy of the steam. The steam in the impeller... Under the action of the steam, the steam is accelerated and enters the interior of the inactivation tank body 2 from above the steam conveying pipe 13. Due to the good permeability of steam, after being pressurized by the booster pump 14, it can penetrate into the tiny gaps and holes inside the inactivation tank body 2. Through the principle of thermal expansion and contraction, tiny gaps are created between the residual dirt and the inner wall of the inactivation tank body, making it easier to fall off. Finally, the control valve above the discharge port 22 is opened, and the cleaned impurities are discharged from the discharge port 22 along with the condensate formed during the condensation process, greatly improving the cleaning effect.
[0023] It should be noted that this utility model is an antigen inactivation tank device for vaccine production. During initial cleaning, the transmission rod 6 is rotated by the first motor 5 to raise the sealing cover 3, positioning the stirring rod 9 above the inactivation tank body 2. A cleaning machine is then added to the interior of the inactivation tank body 2, and workers can use a soft cleaning brush to clean the inside. Next, the first motor 5 is started to seal the inactivation tank body 2 with the sealing cover 3. The control valve above the discharge port 22 is tightened, and the steam valve on the left side of the booster pump 14 is opened to slowly introduce a small amount of steam to preheat the steam delivery pipe 13 and the interior of the inactivation tank body 2, preventing damage due to sudden temperature changes. Simultaneously, the steam delivery pipe 13 and the inactivation tank body 2 are checked for leaks. After preheating, the steam flow rate is gradually increased to ensure even distribution of steam inside the inactivation tank body 2, allowing the steam to continue acting within the inactivation tank body 2 for a period of time. The high temperature and humidity of steam soften and decompose dirt, and kill microorganisms. The softened dirt falls to the bottom of the inactivation tank body 2. After opening the control valve above the discharge port 22, the condensate is discharged and connected to the water storage tank 10 through the water inlet pipe 11 to the external water supply equipment. Under the action of the filter screen 21, impurities in the water can be effectively filtered. When the staff needs to clean the inside of the discharge port 22 pipe, they only need to close the control valve above the steam delivery pipe 13 and open the control valve above the diversion pipe 15. Under the action of the booster pump 14, the steam inside the water storage tank 10 is delivered to the inside of the connecting hose 17 and sprayed out from the spray gun 16. The staff can hold the spray gun 16 and aim it at the inside of the discharge port 22 for cleaning, which greatly improves the work efficiency. The spring buckle 19 makes it easy for the staff to store the spray gun 16. At the same time, the connecting hose 17 can be wrapped around the cable rack 18 to avoid tangling.
[0024] The foregoing has shown and described the basic principles, main features, and advantages of this utility model. Those skilled in the art should understand that this utility model is not limited to the above embodiments. The embodiments and descriptions in the specification are merely illustrative of the principles of this utility model. Various changes and modifications can be made to this utility model without departing from its spirit and scope, and all such changes and modifications fall within the scope of the claims. The scope of protection of this utility model is defined by the appended claims and their equivalents.
Claims
1. An antigen inactivation vessel for vaccine production, comprising a base (1), characterized in that: A water storage tank (10) is provided on the upper right side of the base (1). A water inlet pipe (11) and a sewage pipe (12) are provided on the bottom right side of the water storage tank (10). A filter screen (21) is provided inside the water inlet pipe (11). Multiple heating pipes (20) are provided inside the water storage tank (10). An inactivation tank body (2) is provided on the upper left side of the base (1). A steam conveying pipe (13) is provided between the water storage tank (10) and the inactivation tank body (2). A booster pump (14) is provided above the steam conveying pipe (13). A diversion pipe (15) is provided on the outer side of the front end of the steam conveying pipe (13). A connecting hose (17) is provided inside the diversion pipe (15). A spray gun (16) is provided at the other end of the connecting hose (17). Two sets of spring clips (19) are provided on the outer surface of the front end of the water storage tank (10). A cable management rack (18) is provided on the left side of the water storage tank (10).
2. The antigen inactivation tank equipment for vaccine production according to claim 1, characterized in that: The inactivation tank body (2) has a double-layer structure. Multiple heating coils (23) are installed inside the inactivation tank body (2). A discharge port (22) is provided at the front of the lower end of the inactivation tank body (2). A column (4) is provided at the rear of the inactivation tank body (2). A first motor (5) is provided at the upper end of the column (4). A transmission rod (6) is provided inside the column (4). The upper end of the transmission rod (6) is connected to the rotor end of the first motor (5). A mounting bracket (7) is provided at the front end of the column (4). A sealing cover (3) is provided below the mounting bracket (7). A second motor (8) is provided at the middle position of the upper outer surface of the sealing cover (3). A stirring rod (9) is provided below the sealing cover (3). The upper end of the stirring rod (9) is connected to the rotor end of the second motor (8).
3. The antigen inactivation tank equipment for vaccine production according to claim 1, characterized in that: The water storage tank (10) is fixedly installed on the upper right side of the base (1). The heating tube (20) is detachably installed inside the water storage tank (10). The water inlet pipe (11) and the sewage pipe (12) are welded to the bottom right side of the water storage tank (10). The filter screen (21) is detachably installed inside the water inlet pipe (11).
4. The antigen inactivation tank equipment for vaccine production according to claim 1, characterized in that: The two ends of the steam conveying pipe (13) are detachably connected to the inactivation tank body (2) and the water storage tank (10) respectively. The booster pump (14) is detachably installed above the steam conveying pipe (13). The diversion pipe (15) is fixedly welded to the outer side of the front end of the steam conveying pipe (13). The spray gun (16) is detachably connected to the diversion pipe (15) through the set connecting hose (17). The spring buckle (19) is fixedly set at the front end of the water storage tank (10). The cable rack (18) is fixedly set on the left side of the water storage tank (10) by welding.
5. The antigen inactivation tank equipment for vaccine production according to claim 2, characterized in that: The column (4) is fixedly installed above the base (1) by welding. The first motor (5) is detachably installed on the upper end of the column (4). The upper end of the transmission rod (6) is detachably connected to the rotor end of the first motor (5). The transmission rod (6) is threadedly connected to the mounting bracket (7).
6. The antigen inactivation tank equipment for vaccine production according to claim 2, characterized in that: The sealing cover (3) is fixedly installed below the mounting bracket (7), the second motor (8) is detachably installed on the upper outer surface of the sealing cover (3), and the upper end of the stirring rod (9) is detachably connected to the rotor end of the second motor (8).