A bionic stomach structure with a four-star type pylorus and a bionic digestive system

Abstract

The utility model relates to a kind of bionic stomach structure and bionic digestive system with four-star pylorus, including pylorus and pylorus clamp, pylorus includes pylorus main body, and four-star through-hole is set up on pylorus main body;Pylorus clamp includes the first clamping plate and the second clamping plate symmetrically arranged on the upper and lower sides of pylorus main body, and the side of first clamping plate and second clamping plate close to pylorus main body is respectively provided with first flange and second flange.This bionic stomach structure with four-star pylorus is provided with the pylorus structure with unique inner hole shape, so that the inner hole of pylorus is close to the shape of a small hole when it is closed, more close to the real state of human pylorus when it is closed;And the structure of pylorus clamp is redesigned, a certain movement space is left for the driving mechanism of driving bionic stomach peristalsis, so that driving mechanism can be moved to the position of pylorus, provide conditions for further study the role of pylorus in digestive terminal.

Description

Technical Field

[0001] This utility model relates to the field of bionic stomach technology, and in particular to a bionic stomach structure and a bionic digestive system with a four-pointed star-shaped pylorus. Background Technology

[0002] In food and pharmaceutical research, objectively and accurately assessing the digestive process of food and drugs in the human body is crucial for determining food and drug components and their effects on the human digestive tract. In vitro human digestive tract simulators are devices that biomimeticly simulate the human digestive system, its digestive environment, and the fluid dynamics within the digestive tract. They can simulate the digestive process of different samples in an in vitro model, thus providing a wealth of valuable data for the development of novel functional foods. Therefore, in vitro human digestive tract simulators are becoming increasingly critical in research on food, pharmaceuticals, and even microorganisms, greatly facilitating research in food science and human nutrition.

[0003] Patent CN108735060A discloses a biomimetic human esophagus and stomach digestive system to simulate the human stomach digestion and emptying process. It includes a biomimetic stomach, a rolling compression device, and a pyloric clamp. The pyloric clamp structure consists of two clamping plates (fixed and movable parts) that can clamp. In actual experiments, the clamping plates interfere with the movement of the rollers of the rolling compression device, preventing the rollers from reaching a position closer to the pylorus. This limits further research on the role of the pylorus at the end of digestion. Furthermore, the existing pyloric structure uses a circular tube structure. After being clamped and compressed by the pyloric clamp, the "pyloric opening" becomes a flat slit, which is different from the actual structure of the pylorus after contraction. Utility Model Content

[0004] Therefore, the technical problem to be solved by this utility model is to overcome the fact that the pyloric clamp structure in the prior art interferes with the movement of the roller of the rolling extrusion device, making it impossible for the roller to reach a position closer to the pylorus, which limits further research on the role of the pylorus at the end of digestion; and the existing pyloric structure is a circular tube structure, and after the pyloric structure is clamped and extruded by the pyloric clamp, its "pyloric opening" becomes a flat slit, which is different from the actual structure of the pylorus after contraction.

[0005] To solve the above-mentioned technical problems, this utility model provides a biomimetic stomach structure with a four-pointed star-shaped pylorus, including a biomimetic stomach and a drive mechanism symmetrically arranged on both sides of the biomimetic stomach to drive its peristalsis.

[0006] The pylorus includes a pyloric body, which is disposed in a bionic stomach, and a four-pointed star-shaped through hole is coaxially opened on the pyloric body;

[0007] The pyloric clamp includes a first clamping plate and a second clamping plate symmetrically arranged on the upper and lower sides of the pyloric body. The first clamping plate and the second clamping plate are both located on the side of the pyloric body away from the driving mechanism, and the first clamping plate and the second clamping plate are respectively provided with a first flange and a second flange corresponding to the position of the pyloric body on the side of the first clamping plate and the second clamping plate close to the pyloric body.

[0008] In one embodiment of this utility model, the pyloric body is cylindrical, and two ends of the pyloric body are coaxially provided with circular grooves to form a thinning region located between the two circular grooves. The through hole is coaxially opened on the thinning region.

[0009] In one embodiment of the present invention, the first clamping plate is fixedly disposed, and the second clamping plate is connected to a driving source for driving it to move closer to or away from the first clamping plate.

[0010] In one embodiment of the present invention, both the first clamping plate and the second clamping plate are rectangular plates. The first clamping plate is horizontally arranged, the second clamping plate is vertically arranged, and at least two limiting portions are vertically arranged at the bottom of the first clamping plate, respectively located on both sides of the second clamping plate. The distance between the two limiting portions matches the width of the second clamping plate.

[0011] In one embodiment of the present invention, the free end of the limiting part is provided with rounded corners, and the edges of the second clamping plate near the first clamping plate are all provided with rounded corners.

[0012] In one embodiment of this utility model, the opposite sides of the first flange and the second flange are both horizontal surfaces and are respectively provided with protrusions corresponding to the position of the pyloric body.

[0013] In one embodiment of the present invention, at least two first connecting holes are vertically formed on the first clamping plate.

[0014] In one embodiment of the present invention, two second connecting holes are symmetrically provided at the bottom of the second clamping plate, and two third connecting holes are provided at both ends of the second clamping plate, which respectively connect to the two second connecting holes.

[0015] In one embodiment of this utility model, the pylorus body is made of an elastic material.

[0016] A biomimetic digestive system comprising a biomimetic stomach structure with a four-pointed star-shaped pylorus as described in any of the preceding claims.

[0017] The above-mentioned technical solution of this utility model has the following advantages compared with the prior art:

[0018] This invention discloses a biomimetic stomach structure and biomimetic digestive system with a four-pointed star-shaped pylorus. The pylorus includes a pyloric body with a four-pointed star-shaped through-hole. The pyloric clamp includes a first clamping plate and a second clamping plate symmetrically arranged on the upper and lower sides of the pyloric body. Both the first and second clamping plates are located on the side of the pyloric body furthest from the driving mechanism, and the first and second clamping plates, respectively, have a first flange and a second flange corresponding to the position of the pyloric body on the side closest to the pyloric body. This biomimetic stomach structure with a four-pointed star-shaped pylorus features a uniquely shaped pyloric structure, making its inner hole resemble a small hole when closed, more closely resembling the actual state of the human pylorus when closed. Furthermore, the pyloric clamp structure has been redesigned to provide sufficient space for the driving mechanism that drives the biomimetic stomach's peristalsis while still ensuring proper clamping and compression of the pylorus. This allows the driving mechanisms on both sides of the biomimetic stomach to move closer to the pylorus, providing conditions for further research on the role of the pylorus at the end of digestion. Attached Figure Description

[0019] To make the content of this utility model easier to understand, the present utility model will be further described in detail below with reference to specific embodiments and accompanying drawings.

[0020] Figure 1 This is a schematic diagram of the pylorus in its natural state, representing a preferred embodiment of the present invention, featuring a biomimetic gastric structure with a four-pointed star-shaped pylorus.

[0021] Figure 2 This is a schematic diagram of the pylorus under compression state of the biomimetic stomach structure with a four-pointed star-shaped pylorus according to a preferred embodiment of the present invention.

[0022] Figure 3 This is a perspective view of a pyloric clamp with a biomimetic stomach structure having a four-pointed star-shaped pylorus, according to a preferred embodiment of the present invention.

[0023] Figure 4 This is a schematic diagram of the pyloric clamp with a biomimetic gastric structure having a four-pointed star-shaped pylorus, according to a preferred embodiment of the present invention.

[0024] Figure 5 This is a schematic diagram showing the position of the pylorus in the bionic stomach with a four-pointed star-shaped pylorus, according to a preferred embodiment of the present invention.

[0025] Figure 6 This is a schematic diagram showing the position of the pyloric clamp and the driving mechanism in a preferred embodiment of the present invention, which features a biomimetic stomach structure with a four-pointed star-shaped pylorus.

[0026] Explanation of reference numerals in the accompanying drawings: 1. Pylorus; 11. Pylorus body; 111. Thinning area; 12. Through hole; 2. Pylorus clamp; 21. First clamping plate; 211. First flange; 212. Limiting part; 22. Second clamping plate; 221. Second flange; 3. Drive source; A. Bionic stomach; B. Drive mechanism. Detailed Implementation

[0027] The present invention will be further described below with reference to the accompanying drawings and specific embodiments, so that those skilled in the art can better understand and implement the present invention. However, the embodiments are not intended to limit the present invention. Example 1

[0028] Reference Figures 1-6 As shown, this utility model discloses a biomimetic stomach structure with a four-pointed star-shaped pylorus, comprising a biomimetic stomach A and a driving mechanism B symmetrically arranged on both sides of the biomimetic stomach to drive its peristalsis.

[0029] Pylorus 1, which includes a pyloric body 11, which is located in a bionic stomach, and a four-pointed star-shaped through hole 12 is coaxially opened on the pyloric body 11.

[0030] The pyloric clamp 2 includes a first clamping plate 21 and a second clamping plate 22 symmetrically arranged on the upper and lower sides of the pyloric body 11. The first clamping plate 21 and the second clamping plate 22 are both located on the side of the pyloric body 11 away from the driving mechanism, and the first clamping plate 21 and the second clamping plate 22 are respectively provided on the side of the first clamping plate 21 and the second clamping plate 22 that are close to the pyloric body 11, corresponding to the position of the pyloric body 11.

[0031] Specifically, the first clamp 21 is fixed to the base via a connecting frame and is located above the bionic stomach. The second clamp 22 is connected to the drive source 3 located on the base and is located below the bionic stomach, corresponding to the position of the first clamp 21. The drive source 3 can drive the second clamp 22 to move toward the first clamp 21, thereby clamping and squeezing the pyloric body 11 located between the two. The pyloric body 11 is made of an elastic material such as rubber. When the pyloric body 11 is squeezed, the four-pointed star-shaped through hole 12 will gradually become smaller, thereby simulating the contraction and closure process of the pylorus. Due to the unique shape of the four-pointed star-shaped through hole, the inner hole of the pyloric body 11 is close to the shape of a small hole when closed. Compared with the original pyloric structure, it is closer to the real structure of the human pylorus, thus better simulating the real state of the pylorus.

[0032] Specifically, the pyloric clamp 2 is positioned on the side of the pylorus 1 away from the driving mechanism. The first clamping plate 21 and the second clamping plate 22 serve as the main body, with the first flange 211 and the second flange 221 extending above and below the pylorus 1 as clamping parts. It is conceivable that the volume of the pylorus 1 is relatively small compared to the stomach body. The width of the first flange 211 and the second flange 221 is designed according to the diameter or width of the pylorus 1. In this way, it can not only meet the needs of clamping the pyloric body 11, but also leave a certain working space on both sides of the first flange 211 and the second flange 221 compared to the original overall clamping plate structure. This allows the driving mechanism on both sides of the bionic stomach to have a larger range of movement, thereby being able to move to a position closer to the pylorus 1, providing conditions for further research on the role of the pylorus 1 at the end of digestion.

[0033] This invention discloses a biomimetic stomach structure with a four-pointed star-shaped pylorus. The pylorus 1 structure features a uniquely shaped inner hole, so that when closed, its inner hole resembles a small aperture, more closely mimicking the actual state of the human pylorus when closed. Furthermore, the pylorus clamp 2 structure has been redesigned. While ensuring proper clamping and compression of the pylorus 1, it also provides sufficient space for the drive mechanism that drives the biomimetic stomach's peristalsis. This allows the drive mechanisms on both sides of the biomimetic stomach to move closer to the pylorus 1, providing conditions for further research on the role of the pylorus 1 at the end of digestion.

[0034] Reference Figure 1 and Figure 2 As shown, the pyloric body 11 is cylindrical, with coaxial circular grooves at both ends forming a thinned region 111 between the two grooves. A through-hole 12 is coaxially formed on the thinned region 111. Specifically, the thinned region 111 has better flexibility, making it easier for the star-shaped through-hole 12 to undergo controllable deformation under external force, simulating the contraction and relaxation functions of a real pylorus 1. Furthermore, the structure of a real pylorus has non-uniform thickness and complex geometric features. The combination of the thinned region 111 and the star-shaped through-hole 12, through engineering simplification, achieves similar fluid resistance variations and peristaltic wave conduction characteristics, which is closer to biomechanical behavior than uniform thickness or simple circular holes.

[0035] Reference Figure 3 and Figure 4 As shown, the first clamping plate 21 is fixedly installed, and the second clamping plate 22 is connected to a drive source 3 for driving it to move closer to or further away from the first clamping plate 21. Specifically, a telescopic drive source can be used to directly drive the second clamping plate 22 to move, or a rotary drive source can be used in conjunction with a gear and rack structure to drive the second clamping plate 22 to move. It is conceivable that the driving method of the pyloric clamp 2 is not limited to the above forms; the second clamping plate can be fixed while the first clamping plate moves, or the first and second clamping plates can move simultaneously through a drive structure.

[0036] Furthermore, both the first clamping plate 21 and the second clamping plate 22 are rectangular plates. The first clamping plate 21 is horizontally arranged, and the second clamping plate 22 is vertically arranged. At least two limiting portions 212 are vertically arranged at the bottom of the first clamping plate 21, located on both sides of the second clamping plate 22. The distance between the two limiting portions 212 matches the width of the second clamping plate 22. It is conceivable that the limiting portions 212 can guide and limit the second clamping plate 22 in the width direction, making the clamping and squeezing process of the pyloric clamp 2 on the pylorus 1 more stable, which to some extent improves the accuracy of the experiment.

[0037] Furthermore, the free end of the limiting part 212 is provided with rounded corners, and the edges of the side of the second clamping plate 22 near the first clamping plate 21 are all provided with rounded corners.

[0038] Furthermore, the opposite sides of the first flange 211 and the second flange 221 are both horizontal surfaces and are respectively provided with protrusions corresponding to the positions of the pyloric body 11.

[0039] Furthermore, at least two first connecting holes are vertically provided on the first clamping plate 21, and the first clamping plate 21 is fixed to the connecting frame through the first connecting holes and fasteners.

[0040] Furthermore, two second connecting holes are symmetrically provided at the bottom of the second clamping plate 22, and two third connecting holes are provided at both ends of the second clamping plate 22, which respectively connect to the two second connecting holes. Specifically, the output shaft of the drive source 3 is inserted into the second connecting hole, and the threaded hole on the side of the output shaft of the drive source 3 is aligned with the third connecting hole that connects to the second connecting hole. Then, a screw is inserted into the third connecting hole and screwed into the threaded hole to connect the drive source 3 and the second clamping plate 22.

[0041] Furthermore, the main body 11 of the pylorus is made of an elastic material, specifically rubber. Example 2

[0042] This utility model also discloses a biomimetic digestive system, including a biomimetic stomach structure with a four-pointed star-shaped pylorus as in Example 1.

[0043] Obviously, the above embodiments are merely illustrative examples for clear explanation and are not intended to limit the implementation. Those skilled in the art will recognize that other variations or modifications can be made based on the above description. It is neither necessary nor possible to exhaustively list all possible implementations here. However, obvious variations or modifications derived therefrom are still within the protection scope of this invention.

Claims

1. A biomimetic stomach structure with a four-pointed star-shaped pylorus, comprising a biomimetic stomach and drive mechanisms symmetrically arranged on both sides of the biomimetic stomach to drive its peristalsis, characterized in that: include, The pylorus includes a pyloric body, which is disposed in a bionic stomach, and a four-pointed star-shaped through hole is coaxially opened on the pyloric body; The pyloric clamp includes a first clamping plate and a second clamping plate symmetrically arranged on the upper and lower sides of the pyloric body. The first clamping plate and the second clamping plate are both located on the side of the pyloric body away from the driving mechanism, and the first clamping plate and the second clamping plate are respectively provided with a first flange and a second flange corresponding to the position of the pyloric body on the side of the first clamping plate and the second clamping plate close to the pyloric body.

2. The biomimetic stomach structure with a four-pointed star-shaped pylorus according to claim 1, characterized in that: The pyloric sphincter body is cylindrical, and coaxial circular grooves are provided at both ends of the pyloric sphincter body to form a thinning region located between the two circular grooves. The through hole is coaxially opened on the thinning region.

3. The biomimetic stomach structure with a four-pointed star-shaped pylorus according to claim 1, characterized in that: The first clamping plate is fixedly installed, and the second clamping plate is connected to a drive source for driving it to move closer to or away from the first clamping plate.

4. The biomimetic stomach structure with a four-pointed star-shaped pylorus according to claim 1, characterized in that: Both the first clamping plate and the second clamping plate are rectangular plates. The first clamping plate is horizontally arranged, and the second clamping plate is vertically arranged. At least two limiting parts are vertically arranged at the bottom of the first clamping plate, respectively located on both sides of the second clamping plate. The distance between the two limiting parts matches the width of the second clamping plate.

5. The biomimetic stomach structure with a four-pointed star-shaped pylorus according to claim 4, characterized in that: The free end of the limiting part is provided with rounded corners, and the edges of the second clamping plate near the first clamping plate are all provided with rounded corners.

6. The biomimetic stomach structure with a four-pointed star-shaped pylorus according to claim 1, characterized in that: The opposing sides of the first flange and the second flange are both horizontal surfaces and are respectively provided with protrusions corresponding to the position of the pyloric body.

7. The biomimetic stomach structure with a four-pointed star-shaped pylorus according to claim 1, characterized in that: The first clamping plate has at least two first connecting holes vertically formed.

8. The biomimetic stomach structure with a four-pointed star-shaped pylorus according to claim 7, characterized in that: The bottom of the second clamping plate has two symmetrical second connecting holes, and both ends of the second clamping plate have two third connecting holes that connect to the two second connecting holes respectively.

9. The biomimetic stomach structure with a four-pointed star-shaped pylorus according to claim 1, characterized in that: The main body of the pylorus is made of elastic material.

10. A biomimetic digestive system, characterized in that: Including the biomimetic stomach structure with a four-pointed star-shaped pylorus as described in any one of claims 1-9.

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