Negative pressure pelletizing isolator

Abstract

This utility model provides a negative pressure granulation isolator, relating to the technical field of granulation isolating equipment. It includes: an unpacking chamber, a crushing and weighing chamber, a feeding chamber, a transfer window assembly, a door assembly, and a negative pressure mechanism. The unpacking chamber contains an unpacking machine. The crushing and weighing chamber is sealed to the unpacking chamber and contains a crusher and an electronic balance. The feeding chamber is sealed to the crushing and weighing chamber and the feeding tank. The transfer window assembly is located between the unpacking chamber and the crushing and weighing chamber, and between the crushing and weighing chamber and the feeding chamber. The door assembly is located on the operator-facing side of the unpacking chamber, the crushing and weighing chamber, and the feeding chamber, and has a transparent viewing window and a glove operating opening. The negative pressure mechanism is connected to the unpacking chamber, the crushing and weighing chamber, and the feeding chamber, so that the unpacking chamber, the crushing and weighing chamber, and the feeding chamber are under negative pressure during operation. This gives it the advantages of high integration and good sealing performance.

Description

Technical Field

[0001] This utility model relates to the field of granulation isolation equipment technology, and in particular to a negative pressure granulation isolator. Background Technology

[0002] Granulation is a crucial step in pharmaceutical production, typically involving multiple steps such as unpacking, crushing, weighing, and feeding. These processes require extremely high levels of cleanliness in the operating environment and strict safety controls for personnel, especially when handling active pharmaceutical ingredients (APIs), to prevent dust leaks that could harm the environment and workers.

[0003] Existing granulation isolation equipment generally only provides isolation and protection for a single process, such as having only an unpacking isolation chamber or a crushing isolation chamber; and the material transfer sealing performance between the isolation chambers is insufficient, which reduces the safety and convenience of operation for operators.

[0004] Therefore, a highly integrated and well-sealed negative pressure particle isolator needs to be designed. Utility Model Content

[0005] The purpose of this utility model is to provide a negative pressure particle separator that addresses the defects and shortcomings of the existing technology, thereby solving at least one of the aforementioned technical problems. It has the advantages of high integration and good sealing performance.

[0006] To achieve the above objectives, this utility model provides a negative pressure particle separator, comprising:

[0007] The unpacking compartment is equipped with an unpacking machine for unpacking materials.

[0008] The crushing and weighing chamber is sealed to the unpacking chamber and contains a crusher and an electronic balance for crushing, weighing and dispensing materials.

[0009] The feeding chamber is sealed to the crushing and weighing chamber and the feeding tank, and is used to feed the packaged materials into the feeding tank.

[0010] A transfer window assembly is respectively disposed between the unpacking chamber and the crushing and weighing chamber, and between the crushing and weighing chamber and the feeding chamber, for sealed transfer between the chambers;

[0011] The door assemblies are respectively located on the operator-facing side of the unpacking compartment, the crushing and weighing compartment, and the feeding compartment, and have transparent windows and glove operating openings for isolation from the outside world and operation.

[0012] The negative pressure mechanism is connected to the unpacking chamber, the crushing and weighing chamber, and the feeding chamber, respectively, so that the unpacking chamber, the crushing and weighing chamber, and the feeding chamber are in a negative pressure state during operation.

[0013] Optionally, inter-compartment transfer ports are provided between the unpacking compartment and the crushing and weighing compartment, and between the crushing and weighing compartment and the feeding compartment;

[0014] The pass-through window component includes:

[0015] A sealed door, one end of which is hinged to the edge of the inter-cabin transfer port, and the other end of which is locked to the inter-cabin transfer port by a locking device;

[0016] The first inflatable sealing ring is disposed on the sealing surface between the sealing door and the inter-cabin transfer port wall.

[0017] Optionally, the unpacking compartment, the crushing and weighing compartment, and the feeding compartment are each provided with a door assembly port;

[0018] The hatch assembly includes:

[0019] The operating hatch has one end hinged to the edge of the hatch assembly opening, and the other end locked to the hatch assembly opening via an electric lock.

[0020] The second inflatable sealing ring is disposed on the sealing surface between the operating hatch and the hatch assembly opening;

[0021] A gas spring hydraulic rod assembly is disposed on both sides of the operating hatch, with one end connected to the operating hatch and the other end connected to the outer shell of the hatch, and is used to provide clamping force when the operating hatch is closed.

[0022] Optionally, the negative pressure mechanism includes:

[0023] Three air intake fans are respectively connected to the unpacking chamber, the crushing and weighing chamber and the feeding chamber to provide fresh air;

[0024] Three exhaust fans are connected to the unpacking chamber, the crushing and weighing chamber and the feeding chamber respectively, for exhaust purposes;

[0025] Three sensor assemblies are respectively installed in the unpacking chamber, the crushing and weighing chamber and the feeding chamber, for monitoring the pressure difference and temperature and humidity inside the chamber;

[0026] The controller is electrically connected to the air intake fan, the exhaust fan, and the sensor assembly, and is used to control the negative pressure state in the unpacking chamber, the crushing and weighing chamber, and the feeding chamber.

[0027] Optionally, the negative pressure particle isolator also includes:

[0028] An air inlet filter is provided in the air passage between the air inlet fan and the unpacking chamber, in the air passage between the air inlet fan and the crushing and weighing chamber, and in the air passage between the air inlet fan and the feeding chamber.

[0029] An exhaust filter is provided in the air passage between the unpacking chamber and the exhaust fan, in the air passage between the crushing and weighing chamber and the exhaust fan, and in the air passage between the feeding chamber and the exhaust fan.

[0030] Optionally, the sensor assembly includes a differential pressure sensor and a temperature and humidity sensor.

[0031] Optionally, the negative pressure granulator further includes a continuous bagging assembly, which is located on the side of the unpacking chamber away from the crushing and weighing chamber and is sealed to the unpacking chamber for transferring unpacked material into the unpacking chamber during operation.

[0032] Optionally, the unpacking compartment is provided with a transfer port on the side away from the crushing and weighing compartment;

[0033] The continuous bagging assembly includes:

[0034] The T-shaped connecting sleeve has one end of its flange sealed to the transfer port via a sealing ring.

[0035] The transfer door is hinged at one end to the edge of the transfer opening, and locked at the other end to the edge of the transfer opening via a locking assembly;

[0036] The third inflatable sealing ring is located on the sealing surface between the inner wall of the T-shaped connecting sleeve and the transfer door.

[0037] Optionally, the crushing and weighing chamber is also equipped with an air spray gun and a water spray gun;

[0038] The air spray gun is connected to an external air source, and the water spray gun is connected to an external water source, used to clean the crushing and weighing chamber after production.

[0039] The bottom of the crushing and weighing chamber is equipped with a funnel structure, which is connected to the waste liquid treatment device.

[0040] Optionally, the negative pressure granulator further includes a frame and an electrical control box; the unpacking chamber, the crushing and weighing chamber, the feeding chamber, the negative pressure mechanism, and the electrical control box are all mounted on the frame; the electrical control box is electrically connected to the unpacking machine, the crusher, the electronic balance, and the negative pressure mechanism, and is used to provide power and control their operation.

[0041] Compared with the prior art, the advantages of this application are:

[0042] This negative pressure granulator integrates an unpacking chamber, a crushing and weighing chamber, and a feeding chamber. The unpacking chamber is equipped with an unpacking machine, and the crushing and weighing chamber is equipped with a crusher and an electronic balance. A transfer window assembly ensures a sealed connection between the chambers. Each chamber has an operating door and operates under negative pressure. This allows the entire material handling process to be completed in a negative pressure, sealed environment, effectively preventing the leakage of harmful dust and ensuring operator safety. Independent operation and sealed transfer between chambers avoid cross-contamination, improving production cleanliness and system integration. It features a compact structure, excellent sealing, and high safety. Attached Figure Description

[0043] To more clearly illustrate the technical solutions in the embodiments of this utility model or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are only embodiments of this utility model. For those skilled in the art, other drawings can be obtained based on the provided drawings without creative effort.

[0044] Figure 1 This is a process flow diagram of the negative pressure particle separator according to an embodiment of the present invention;

[0045] Figure 2 This is a schematic diagram of the structure of the negative pressure particle isolator according to an embodiment of the present invention;

[0046] Figure 3 This is a front view of the over-negative pressure particle isolator according to an embodiment of the present invention;

[0047] Figure 4 This is a schematic diagram of the structure of the hidden door assembly of the negative pressure particle isolator according to an embodiment of the present invention;

[0048] Figure 5 This is a front view of the hidden door assembly of the negative pressure particle isolator according to an embodiment of the present invention;

[0049] Figure 6 This is a partially exploded structural diagram of the transfer window assembly according to an embodiment of the present utility model;

[0050] Figure 7 This is a partial exploded view of the door assembly according to an embodiment of the present utility model;

[0051] Figure 8 This is a partial exploded view of the gas spring hydraulic rod assembly according to an embodiment of the present utility model;

[0052] Figure 9 This is a partially exploded structural diagram of the continuous bagging assembly according to an embodiment of the present invention;

[0053] Explanation of reference numerals in the attached figures

[0054] 100-Negative pressure particle isolator;

[0055] 1-Unpacking compartment;

[0056] 2-Pulverizing and weighing chamber; 21-Pulverizer; 22-Electronic balance; 23-Air spray gun; 24-Water spray gun; 25-Function funnel structure;

[0057] 3-Feeding compartment; o1-Feeding port;

[0058] 4-Pass-through window assembly; 41-Sealed door; 42-First inflatable sealing ring; 43-Hinge structure; 44-Electronic lock;

[0059] 5-Door assembly; 51-Operating hatch; 52-Glove operating port; 52-Second inflation seal ring; 53-Gas spring hydraulic rod assembly; 531-Gas spring hydraulic rod first base; 532-Gas spring cylinder; 533-Gas spring stroke rod; 534-Gas spring hydraulic rod second base; 535-Ball head connector;

[0060] 61-Inlet fan; 62-Exhaust fan; 63-Differential pressure sensor; 64-Temperature and humidity sensor; 65-Inlet filter; 66-Exhaust filter;

[0061] 7-Continuous bagging assembly; 71-T-shaped connecting sleeve; 72-Pass-through door; 73-Sealing ring; 74-Third inflatable sealing ring;

[0062] 81-Rack; 82-Electrical control box; 83-Top nacelle;

[0063] 9-Feeding tank;

[0064] o3-Inter-cabin transfer port; o4-Hill door assembly port; o5-Transfer port. Detailed Implementation

[0065] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0066] It should be noted that the terms "center," "longitudinal," "lateral," "upper," "lower," "front," "rear," "left," "right," "top," "bottom," "inner," "outer," "back," "side," and "circumferential" used in this utility model to indicate the orientation or positional relationship are based on the orientation or positional relationship shown in the accompanying drawings. They are used only for the convenience of describing this utility model and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on this utility model. In addition, the terms "first" and "second" are only used to distinguish multiple parts or structures with the same or similar structures, and do not indicate any special limitation on the arrangement order or connection relationship.

[0067] Please refer to Figure 1 and Figure 9 This utility model provides a negative pressure granulation isolator 100, including: unpacking chamber 1, crushing and weighing chamber 2, feeding chamber 3, transfer window assembly 4, door assembly 5, and negative pressure mechanism.

[0068] Optionally, the unpacking chamber 1, the crushing and weighing chamber 2, and the feeding chamber 3 are installed side by side on the frame 81 of a negative pressure granulator 100.

[0069] The unpacking compartment 1 is equipped with an unpacking machine (not shown in the figure) for unpacking materials. Specifically, the unpacking machine is existing technology, so it will not be discussed in detail here.

[0070] The crushing and weighing chamber 2 is sealed to the unpacking chamber 1. The chamber contains a crusher 21 and an electronic balance 22 for crushing, weighing, and dispensing materials. Understandably, the crusher 21 is used to crush the unpacked materials, and the electronic balance 22 is used to weigh the crushed materials before dispensing them. Specifically, the crusher 21 and the electronic balance 22 are existing technologies and will not be elaborated upon here.

[0071] The feeding chamber 3 is sealed to the crushing and weighing chamber 2 and the feeding tank 9, and is used to feed the packaged material into the feeding tank 9. In this embodiment, the bottom of the feeding chamber 3 has a feeding port o1 that is sealed and connected to the feeding tank 9; the feeding tank 9 is correspondingly arranged on the lower side of the feeding chamber 3 and aligned with the feeding port o1. In this way, the packaged material can be directly fed into the feeding tank 9 for subsequent processing.

[0072] A transfer window assembly 4 is provided between the unpacking compartment 1 and the crushing and weighing compartment 2, as well as between the crushing and weighing compartment 2 and the feeding compartment 3, for sealed transfer between the compartments. Understandably, when it is necessary to transfer materials between adjacent compartments, the transfer window assembly 4 is opened; when it is not necessary to transfer materials, the transfer window assembly 4 can be closed to achieve a seal between the compartments.

[0073] The unpacking compartment 1, the crushing and weighing compartment 2, and the feeding compartment 3 are equipped with door assemblies 5 on the operator-facing side. The door assembly 5 has a transparent viewing window (not shown) and a glove operating port o2 for isolation from the outside environment and for operation. Thus, the operator can view the interior of the compartment through the transparent viewing window on the door assembly 5 and, while wearing gloves, reach into the glove operating port o2 to perform various operations on the materials located inside the compartment.

[0074] The negative pressure mechanism is connected to the unpacking chamber 1, the crushing and weighing chamber 2, and the feeding chamber 3 respectively, so that the unpacking chamber 1, the crushing and weighing chamber 2, and the feeding chamber 3 are in a negative pressure state during operation. By maintaining a negative pressure state in each chamber during the unpacking, crushing, weighing, packaging, and feeding processes, the negative pressure mechanism can effectively prevent the leakage of harmful substances, avoid cross-contamination, ensure operational safety, and meet clean production requirements.

[0075] This negative pressure granulator 100 integrates an unpacking chamber 1, a crushing and weighing chamber 2, and a feeding chamber 3. The unpacking chamber 1 is equipped with an unpacking machine, and the crushing and weighing chamber 2 is equipped with a crusher 21 and an electronic balance 22. A transfer window assembly 4 ensures a sealed connection between the chambers. Each chamber has an operating door 51 and operates under negative pressure. This allows the entire material handling process to be completed in a negative pressure, sealed environment, effectively preventing the leakage of harmful dust and ensuring operator safety. Independent operation and sealed transfer between chambers avoid cross-contamination, improving production cleanliness and system integration. It features a compact structure, good sealing, and high safety.

[0076] To achieve sealed material transfer between compartments, optionally, please refer to... Figure 4 and Figure 6 In this embodiment, inter-chamber transfer ports o3 are respectively provided between the unpacking chamber 1 and the crushing and weighing chamber 2, and between the crushing and weighing chamber 2 and the feeding chamber 3. The transfer window assembly 4 includes: a sealing door 41 and a first inflatable sealing ring 42.

[0077] One end of the sealed door 41 is hinged to the edge of the inter-cabin transfer port o3, and the other end is locked to the inter-cabin transfer port o3 via a locking member; it is used to open and close the transfer port o5. Specifically, in this embodiment, one end of the sealed door 41 is hinged to the edge of the inter-cabin transfer port o3 via a hinge structure 43, and the other end is locked to the inter-cabin transfer port o3 via an electronic lock 44.

[0078] The first inflatable sealing ring 42 is located on the sealing surface between the sealing door 41 and the wall of the inter-chamber transfer port 03. After the door is closed, the first inflatable sealing ring 42 is partially inflated and expands to fill the sealing gap, thereby achieving a tight seal and ensuring the pressure differential isolation between the chambers and the airtightness of material transfer.

[0079] To ensure the sealing reliability and ease of operation of the hatch assembly 5, optionally, please refer to... Figure 3 , Figure 7 and Figure 8 In this embodiment, the unpacking compartment 1, the crushing and weighing compartment 2, and the feeding compartment 3 are each provided with a door assembly port o4. The door assembly 5 includes: an operating door 51, a second inflatable sealing ring 52, and a gas spring hydraulic rod assembly 53.

[0080] One end of the operating hatch 51 is hinged to the edge of the hatch mounting opening o4, and the other end is locked to the hatch mounting opening o4 by an electric lock. Optionally, one end of the operating hatch 51 is hinged to the edge of the hatch mounting opening o4 by a hinge structure 43, and the other end is locked to the hatch mounting opening o4 by an electronic lock 44. In this embodiment, the operating hatch 51 is a transparent glass door, so that its entire area constitutes a transparent window; the operating hatch 51 is provided with a glove operating opening o2.

[0081] The second inflatable sealing ring 52 is located on the sealing surface between the operating hatch 51 and the hatch assembly opening o4.

[0082] The gas spring hydraulic rod assembly 53 is disposed on both sides of the operating hatch 51, with one end connected to the operating hatch 51 and the other end connected to the outer shell of the hatch, and is used to provide clamping force when the operating hatch 51 is closed. Specifically, the gas spring hydraulic rod assembly 53 includes: a first gas spring hydraulic rod base 531, a gas spring cylinder 532, a gas spring stroke rod 533, and a second gas spring hydraulic rod base 534.

[0083] The first base 531 of the gas spring hydraulic rod is located at the edge of the operating hatch 51; the second base 534 of the gas spring hydraulic rod is located on the outer shell of the hatch; the gas spring stroke rod 533 is partially piston-movingly located inside the gas spring cylinder 532; the end of the gas spring cylinder 532 away from the gas spring stroke rod 533 is connected to the first base 531 of the gas spring hydraulic rod via a ball joint connector 535; the end of the gas spring stroke rod 533 away from the gas spring cylinder 532 is connected to the second base 534 of the gas spring hydraulic rod via the ball joint connector 535; the ball joint connector 535 enables omnidirectional flexible linkage. Thus, when the operating hatch 51 is closed, the gas spring hydraulic rod provides an inward auxiliary clamping force, which, together with the second inflatable sealing ring 52, forms a stable and uniform seal, improving the hatch's sealing effect and operational smoothness.

[0084] To precisely maintain the negative pressure state of each compartment, optionally, please refer to... Figure 1 and Figure 5 In this embodiment, the negative pressure mechanism includes: three intake fans 61, three exhaust fans 62, three sensors, and a controller (not shown in the figure).

[0085] Three air intake fans 61 are connected to the unpacking chamber 1, the crushing and weighing chamber 2, and the feeding chamber 3, respectively, to provide fresh air. Specifically, the air intake fans 61 are respectively installed in the top chamber 83 on the upper side of the unpacking chamber 1, the crushing and weighing chamber 2, and the feeding chamber 3, and are connected to the unpacking chamber 1, the crushing and weighing chamber 2, and the feeding chamber 3 through pipelines.

[0086] Three exhaust fans 62 are connected to the unpacking chamber 1, the crushing and weighing chamber 2, and the feeding chamber 3, respectively, for exhaust purposes. Specifically, the exhaust fans 62 are respectively installed in the top chamber 83 on the upper side of the unpacking chamber 1, the crushing and weighing chamber 2, and the feeding chamber 3, and are connected to the unpacking chamber 1, the crushing and weighing chamber 2, and the feeding chamber 3 through pipelines.

[0087] Three sensor assemblies are respectively installed in the unpacking chamber 1, the crushing and weighing chamber 2, and the feeding chamber 3 to monitor the pressure difference and temperature and humidity inside the chambers. Optionally, the sensor assemblies include a differential pressure sensor 63 for detecting the pressure difference between the chamber and the outside environment, and a temperature and humidity sensor 64 for detecting the temperature and humidity inside the chamber.

[0088] The controller is electrically connected to the air intake fan 61, the exhaust fan 62, and the sensor assembly to control the negative pressure state in the unpacking chamber 1, the crushing and weighing chamber 2, and the feeding chamber 3.

[0089] In this way, the controller can automatically adjust the speed of the intake fan 61 and the exhaust fan 62 based on the real-time feedback of pressure difference, temperature and humidity data from the sensor components, so that the unpacking chamber 1, the crushing and weighing chamber 2, and the feeding chamber 3 each maintain a set negative pressure range, effectively preventing gas crosstalk and dust diffusion. Specifically, the controller controlling the speed of the intake fan 61 and the exhaust fan 62 based on the sensor components is existing technology, so it will not be elaborated on here.

[0090] To effectively intercept particles, dust, and microorganisms during the air intake and exhaust process of each compartment, optionally, please refer to... Figure 1 and Figure 5 In this embodiment, air inlet filters 65 are installed in the air passages between the air inlet fan 61 and the unpacking chamber 1, between the air inlet fan 61 and the crushing and weighing chamber 2, and between the air inlet fan 61 and the feeding chamber 3. Exhaust filters 66 are installed in the air passages between the unpacking chamber 1 and the exhaust fan 62, between the crushing and weighing chamber 2 and the exhaust fan 62, and between the feeding chamber 3 and the exhaust fan 62. This improves the cleanliness of the incoming air, protects the internal environment of the chamber, and prevents the leakage of harmful substances, ensuring safety and environmental protection.

[0091] To prevent the negative pressure granulator 100 from opening the door assembly 5 or pausing operation during operation to feed materials into the unpacking chamber 1, optionally, please refer to... Figure 1 and Figure 9In this embodiment, the negative pressure granulator 100 further includes a continuous bagging assembly 7. The continuous bagging assembly 7 is located on the side of the unpacking chamber 1 away from the crushing and weighing chamber 2 and is sealed to the unpacking chamber 1, and is used to transfer unpacked materials into the unpacking chamber 1 during operation.

[0092] Specifically, a transfer port o5 is provided on the side of the unpacking compartment 1 away from the crushing and weighing compartment 2. A T-shaped connecting sleeve 71, a transfer door 72, and a third inflatable sealing ring 74 are included. One end of the flange of the T-shaped connecting sleeve 71 is sealed to the transfer port o5 via a sealing ring 73. One end of the transfer door 72 is hinged to the edge of the transfer port o5, and the other end is locked to the edge of the transfer port o5 via a locking assembly. Specifically, one end of the transfer door 72 is hinged to the edge of the transfer port o5 via a hinge structure 43, and the other end is locked to the edge of the transfer port o5 via an electronic lock 44. The third inflatable sealing ring 74 is located on the sealing surface between the inner wall of the T-shaped connecting sleeve 71 and the transfer door 72.

[0093] In this way, unopened materials can be safely delivered into the unpacking chamber 1 during negative pressure operation without opening the door assembly 5 or stopping the system, ensuring continuous operation and a stable and clean internal environment.

[0094] To clean the crushing and weighing chamber 2 after production is completed, optionally, please refer to... Figure 1 In this embodiment, the crushing and weighing chamber 2 is also equipped with an air spray gun 23 and a water spray gun 24. The air spray gun 23 is connected to an external air source (not shown in the figure), and the water spray gun 24 is connected to an external water source (not shown in the figure), used to clean the crushing and weighing chamber 2 after production. To prevent waste liquid from polluting the external environment, optionally, the bottom of the crushing and weighing chamber 2 is provided with a funnel structure 25, which is connected to a waste liquid treatment device (not shown in the figure) through the funnel structure 25.

[0095] Alternatively, please refer to Figure 2 In this embodiment, the negative pressure granulator 100 further includes a frame 81 and an electrical control box 82. The unpacking chamber 1, the crushing and weighing chamber 2, the feeding chamber 3, the negative pressure mechanism, and the electrical control box 82 are all mounted on the frame 81. The electrical control box 82 is electrically connected to the unpacking machine, the crusher 21, the electronic balance 22, and the negative pressure mechanism, and is used to provide power and control their operation. Understandably, the controller mentioned above is integrated within the electrical control box 82. This improves the structural integration and system automation level of the negative pressure granulator 100.

[0096] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of this application, and are not intended to limit them. Although this application has been described in detail with reference to the foregoing embodiments, those skilled in the art should understand that modifications can still be made to the technical solutions described in the foregoing embodiments, or equivalent substitutions can be made to some or all of the technical features therein. Such modifications or substitutions do not cause the substance of the corresponding technical solutions to deviate from the scope of the technical solutions of the embodiments of this application.

Claims

1. A negative pressure granulation isolator characterized by, include: The unpacking compartment is equipped with an unpacking machine for unpacking materials. The crushing and weighing chamber is sealed to the unpacking chamber and contains a crusher and an electronic balance for crushing, weighing and dispensing materials. The feeding chamber is sealed to the crushing and weighing chamber and the feeding tank, and is used to feed the packaged materials into the feeding tank. A transfer window assembly is respectively disposed between the unpacking chamber and the crushing and weighing chamber, and between the crushing and weighing chamber and the feeding chamber, for sealed transfer between the chambers; The door assemblies are respectively located on the operator-facing side of the unpacking compartment, the crushing and weighing compartment, and the feeding compartment, and have transparent windows and glove operating openings for isolation from the outside world and operation. The negative pressure mechanism is connected to the unpacking chamber, the crushing and weighing chamber, and the feeding chamber, respectively, so that the unpacking chamber, the crushing and weighing chamber, and the feeding chamber are in a negative pressure state during operation.

2. The low pressure granulation isolator of claim 1, wherein, Inter-compartment transfer ports are provided between the unpacking compartment and the crushing and weighing compartment, and between the crushing and weighing compartment and the feeding compartment; The pass-through window component includes: A sealed door, one end of which is hinged to the edge of the inter-cabin transfer port, and the other end of which is locked to the inter-cabin transfer port by a locking device; The first inflatable sealing ring is disposed on the sealing surface between the sealing door and the inter-cabin transfer port wall.

3. The low pressure granulation isolator of claim 1, wherein, The unpacking compartment, the crushing and weighing compartment, and the feeding compartment are each provided with a door assembly port; The hatch assembly includes: The operating hatch has one end hinged to the edge of the hatch assembly opening, and the other end locked to the hatch assembly opening via an electric lock. The second inflatable sealing ring is disposed on the sealing surface between the operating hatch and the hatch assembly opening; A gas spring hydraulic rod assembly is disposed on both sides of the operating hatch, with one end connected to the operating hatch and the other end connected to the outer shell of the hatch, and is used to provide clamping force when the operating hatch is closed.

4. The negative pressure particle separator as described in claim 1, characterized in that, The negative pressure mechanism includes: Three air intake fans are respectively connected to the unpacking chamber, the crushing and weighing chamber and the feeding chamber to provide fresh air; Three exhaust fans are connected to the unpacking chamber, the crushing and weighing chamber and the feeding chamber respectively, for exhaust purposes; Three sensor assemblies are respectively installed in the unpacking chamber, the crushing and weighing chamber and the feeding chamber, for monitoring the pressure difference and temperature and humidity inside the chamber; The controller is electrically connected to the air intake fan, the exhaust fan, and the sensor assembly, and is used to control the negative pressure state in the unpacking chamber, the crushing and weighing chamber, and the feeding chamber.

5. The negative pressure particle separator as described in claim 4, characterized in that, Also includes: An air inlet filter is provided in the air passage between the air inlet fan and the unpacking chamber, in the air passage between the air inlet fan and the crushing and weighing chamber, and in the air passage between the air inlet fan and the feeding chamber. An exhaust filter is provided in the air passage between the unpacking chamber and the exhaust fan, in the air passage between the crushing and weighing chamber and the exhaust fan, and in the air passage between the feeding chamber and the exhaust fan.

6. The negative pressure particle separator as described in claim 4, characterized in that, The sensor assembly includes a differential pressure sensor and a temperature and humidity sensor.

7. The negative pressure particle separator as described in claim 1, characterized in that, It also includes a continuous bagging assembly; the continuous bagging assembly is located on the side of the unpacking chamber away from the crushing and weighing chamber and is sealed to the unpacking chamber, and is used to transfer unpacked materials into the unpacking chamber in the working state.

8. The negative pressure particle separator as described in claim 7, characterized in that, The unpacking compartment is provided with a transfer port on the side away from the crushing and weighing compartment; The continuous bagging assembly includes: The T-shaped connecting sleeve has one end of its flange sealed to the transfer port via a sealing ring. The transfer door is hinged at one end to the edge of the transfer opening, and locked at the other end to the edge of the transfer opening via a locking assembly; The third inflatable sealing ring is located on the sealing surface between the inner wall of the T-shaped connecting sleeve and the transfer door.

9. The negative pressure particle separator as described in claim 1, characterized in that, The crushing and weighing chamber is also equipped with an air spray gun and a water spray gun. The air spray gun is connected to an external air source, and the water spray gun is connected to an external water source, used to clean the crushing and weighing chamber after production. The bottom of the crushing and weighing chamber is equipped with a funnel structure, which is connected to the waste liquid treatment device.

10. The negative pressure particle separator as described in claim 1, characterized in that, It also includes a frame and an electrical control box; the unpacking chamber, the crushing and weighing chamber, the feeding chamber, the negative pressure mechanism, and the electrical control box are all installed on the frame; the electrical control box is electrically connected to the unpacking machine, the crusher, the electronic balance, and the negative pressure mechanism, and is used to provide power and control their operation.

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