A mixer for pharmaceutical production

Abstract

The utility model discloses a mixing machine for pharmaceutical production, including cylinder and be used for supporting the mounting bracket of cylinder, the mounting bracket is fixedly connected with the support column on symmetry, two support column mutual end of approaching is respectively with the both ends rotation connection of cylinder, be provided with the drive assembly for driving cylinder rotation on the mounting bracket, the cylinder is formed by first mixing section, second mixing section and third mixing section mutual splicing, all be provided with the linkage assembly for adjusting the relative rotating speed of each section between first mixing section and second mixing section and between second mixing section and third mixing section, the utility model discloses a mixing machine for pharmaceutical production, through linkage assembly and baffle cooperation, can realize multiple mixing section operation combination, such as only first mixing section operation, first and second mixing section common operation etc, can according to the physical characteristic of different material and the mixing requirement flexible adjustment, improve the adaptive capacity of equipment to different batches, different formula material.

Description

Technical Field

[0001] This utility model relates to the field of pharmaceutical production technology, specifically a mixer used in pharmaceutical production. Background Technology

[0002] In pharmaceutical manufacturing, material mixing is a crucial step in ensuring the uniformity and stability of drug quality, directly affecting subsequent formulation, efficacy, and medication safety. Different types of pharmaceutical raw materials often have different physical properties, such as particle size, density, flowability, and adhesion, which places extremely high demands on the adaptability and mixing precision of mixing equipment.

[0003] Currently, commonly used mixing equipment in the pharmaceutical industry mainly includes trough mixers, cone mixers, and twin-screw mixers. Among them, traditional drum mixers are widely used due to their simple structure and convenient operation. They achieve mixing by rotating the entire drum to tumble the materials inside. However, this type of equipment has significant limitations in practical applications: in small-batch pharmaceutical manufacturing scenarios, the drum has a large margin of space, and the proportion of material tumbling within the drum is low. This can easily lead to material slipping or localized accumulation within the drum. This not only results in a serious waste of power due to ineffective rotation but also prolongs the mixing cycle due to insufficient collision and contact frequency between materials. Utility Model Content

[0004] To address the shortcomings mentioned in the background art, the purpose of this utility model is to provide a mixer for pharmaceutical production, which solves the problems of excessive space, wasted power source, and low mixing efficiency of traditional drum mixers in small-batch pharmaceutical manufacturing scenarios.

[0005] The objective of this utility model can be achieved through the following technical solutions:

[0006] A mixer for pharmaceutical production includes a cylinder and a mounting frame for supporting the cylinder. Support columns are symmetrically fixedly connected to the mounting frame. The ends of two support columns that are close to each other are rotatably connected to the two ends of the cylinder. A drive assembly for driving the cylinder to rotate is provided on the mounting frame. The cylinder is formed by splicing together a first mixing section, a second mixing section and a third mixing section. Linkage components for adjusting the relative rotation speed of each section are provided between the first mixing section and the second mixing section, as well as between the second mixing section and the third mixing section.

[0007] More preferably, the inner wall of the first mixing section is fixedly connected with several fixed baffles, and the first mixing section is provided with an inlet and an outlet. The inner walls of the second and third mixing sections are provided with several movable baffles, and the fixed baffles and movable baffles are distributed in a circumferential array.

[0008] More preferably, the second mixing section and the third mixing section are each provided with a number of receiving boxes equal to the number of movable spoilers. The interior of the receiving box is connected to the cylinder body. The movable spoilers are slidably installed inside the receiving box. An extension spring is fixedly installed between the end of the movable spoiler and the inner wall of the receiving box. The extension spring is used to drive the movable spoiler to extend into the cylinder body.

[0009] More preferably, an electric push rod is provided on the outer axial direction of the third mixing section. The output end of the electric push rod passes through the third mixing section and extends into the interior of the cylinder. A partition is fixedly connected to the output end of the electric push rod. The curved surface of the partition fits against the inner wall of the cylinder. The partition is used to divide the interior of the cylinder into independent working areas and idle areas. When the electric push rod pushes the partition to slide inside the cylinder, it will compress the movable baffle into the receiving box.

[0010] More preferably, the first mixing section and the second mixing section each have a limiting groove on their sides, and the second mixing section and the third mixing section each have a limiting ring fixedly connected to their sides that slides with the limiting groove. The limiting ring of the second mixing section is embedded in the limiting groove of the first mixing section, and the limiting ring of the third mixing section is embedded in the limiting groove of the second mixing section.

[0011] More preferably, the linkage component includes a fixed gear ring and a movable gear ring, the movable gear ring being slidably sleeved on the end of the second mixing section and keyed to the second mixing section, and the fixed gear ring being fixedly installed on the ends of the first mixing section and the third mixing section near the second mixing section.

[0012] More preferably, the linkage assembly further includes a rotating shaft fixedly mounted on the mounting bracket. The rotating shaft is vertically arranged, and a lever is rotatably connected to the rotating shaft. An annular groove is formed on the movable gear ring, and one end of the lever extends into the interior of the annular groove. A fixing post is fixedly mounted on the mounting bracket, and the fixing post and the rotating shaft are arranged parallel to each other. A top sleeve is fitted on the top of the fixing post, and a lifting spring is provided inside the top sleeve. The two ends of the lifting spring are respectively in contact with the top of the fixing post and the top of the inner wall of the top sleeve. When the end of the lever away from the movable gear ring is located on one side of the top sleeve, the movable gear ring and the fixed gear ring are in an engaged state. When the end of the lever away from the movable gear ring is located on the other side of the top sleeve, the movable gear ring and the fixed gear ring are disengaged. When the lifting spring is in a compressed state, the top of the top sleeve is lower than the height of the lever.

[0013] More preferably, the drive assembly includes a gear ring fixedly sleeved on the first mixing section, a rotary motor fixedly mounted on the mounting bracket, and a drive tooth fixedly connected to the output end of the rotary motor, the drive tooth meshing with the gear ring.

[0014] The beneficial effects of this utility model are:

[0015] 1. This utility model, through the cooperation of linkage components and partitions, can realize various combinations of mixing section operation, such as only the first mixing section operating, the first and second mixing sections operating together, etc. It can be flexibly adjusted according to the physical properties and mixing requirements of different materials, thereby improving the equipment's adaptability to different batches and different formulations of materials.

[0016] 2. This utility model uses an electric push rod to push the partition to precisely divide the working area and the idle area. In small-batch pharmaceutical manufacturing scenarios, the size of the working area can be adjusted according to the amount of material, avoiding material "slipping" or local accumulation in an excessively large space and reducing power waste. Attached Figure Description

[0017] The present invention will be further described below with reference to the accompanying drawings.

[0018] Figure 1 This is a schematic diagram of the overall structure of this utility model;

[0019] Figure 2 This is a cross-sectional view of the cylindrical structure of this utility model with one of the two linkage components engaged and the other disengaged.

[0020] Figure 3 This is a schematic diagram of the first hybrid section structure in this utility model;

[0021] Figure 4 This is a cross-sectional view of the second hybrid section structure in this utility model;

[0022] Figure 5 This is a schematic diagram of the linkage component in this utility model.

[0023] In the picture:

[0024] 1. Cylinder; 101. First mixing section; 102. Second mixing section; 103. Third mixing section; 2. Mounting frame; 3. Support column; 4. Drive assembly; 401. Gear ring; 402. Rotary motor; 403. Drive gear; 5. Linkage assembly; 501. Fixed gear ring; 502. Moving gear ring; 503. Rotating shaft; 504. Lever; 505. Annular groove; 506. Fixed stake; 507. Top sleeve; 508. Lifting spring; 6. Fixed spoiler; 7. Inlet; 8. Outlet; 9. Movable spoiler; 10. Receiving box; 11. Push-out spring; 12. Electric push rod; 13. Partition plate; 14. Limiting groove; 15. Limiting ring. Detailed Implementation

[0025] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those skilled in the art without creative effort are within the protection scope of the present utility model.

[0026] In the description of this utility model, it should be understood that the terms "opening", "upper", "lower", "thickness", "top", "middle", "length", "inner", "around" and other terms indicating orientation or positional relationship are only for the convenience of describing this utility model and simplifying the description, and do not indicate or imply that the components or elements referred to must have a specific orientation, or be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of this utility model.

[0027] like Figure 1-5 As shown, a mixer for pharmaceutical production includes a cylinder 1 and a mounting frame 2 for supporting the cylinder 1. Support columns 3 are symmetrically fixedly connected to the mounting frame 2. The ends of the two support columns 3 that are close to each other are rotatably connected to the two ends of the cylinder 1. This connection method can provide support for the stable rotation of the cylinder 1 and ensure that the cylinder 1 will not shift or shake during the mixing process.

[0028] The mounting frame 2 is equipped with a drive assembly 4 for driving the cylinder 1 to rotate. The drive assembly 4 includes a toothed ring 401 fixedly sleeved on the first mixing section 101. A rotary motor 402 is fixedly mounted on the mounting frame 2. The output end of the rotary motor 402 is fixedly connected to a drive tooth 403, which meshes with the toothed ring 401. When the rotary motor 402 is started, the drive tooth 403 drives the toothed ring 401 to rotate, thereby driving the cylinder 1 to rotate as a whole, providing power for material mixing.

[0029] The cylinder 1 is formed by splicing together a first mixing section 101, a second mixing section 102, and a third mixing section 103. Linkage components 5 for adjusting the relative rotational speed of each section are provided between the first mixing section 101 and the second mixing section 102, and between the second mixing section 102 and the third mixing section 103. The linkage components 5 include a fixed gear ring 501 and a movable gear ring 502. The movable gear ring 502 is slidably sleeved on the end of the second mixing section 102, and the fixed gear ring 501 is fixedly installed on the ends of the first mixing section 101 and the third mixing section 103 near the second mixing section 102. Meanwhile, the linkage component 5 also includes a rotating shaft 503 fixedly installed on the mounting frame 2. The rotating shaft 503 is vertically arranged, and a lever 504 is rotatably connected to the rotating shaft 503. An annular groove 505 is opened on the movable gear ring 502. One end of the lever 504 extends into the interior of the annular groove 505. A fixing post 506 is fixedly installed on the mounting frame 2. The fixing post 506 and the rotating shaft 503 are arranged parallel to each other. A top sleeve 507 is fitted on the top of the fixing post 506. A lifting spring 508 is provided inside the top sleeve 507. The two ends of the lifting spring 508 are respectively in contact with the top of the fixing post 506 and the top of the inner wall of the top sleeve 507. When the end of the lever 504 away from the moving gear ring 502 is located on one side of the top sleeve 507, the moving gear ring 502 and the fixed gear ring 501 are engaged, allowing each mixing section to rotate synchronously. When the end of the lever 504 away from the moving gear ring 502 is located on the other side of the top sleeve 507, the moving gear ring 502 and the fixed gear ring 501 are disengaged, allowing each mixing section to rotate relatively independently, thus adjusting the relative speed of each section to meet the mixing requirements of different materials. When the lifting spring 508 is compressed, the top of the top sleeve 507 is lower than the height of the lever 504, facilitating the rotation operation of the lever 504.

[0030] The inner wall of the first mixing section 101 is fixedly connected with several fixed baffles 6, which are arranged in a circumferential array. These baffles can disturb the material during the rotation of the cylinder 1, thereby increasing the degree of mixing. The first mixing section 101 is provided with an inlet 7 and an outlet 8 for easy addition and removal of the material.

[0031] The inner walls of the second mixing section 102 and the third mixing section 103 are provided with several movable baffles 9, which are also arranged in a circumferential array. Both the second mixing section 102 and the third mixing section 103 are provided with the same number of receiving boxes 10 as the movable baffles 9. The interior of the receiving box 10 is connected to the cylinder 1. The movable baffles 9 are slidably installed inside the receiving box 10. A push-out spring 11 is fixedly installed between the end of the movable baffle 9 and the inner wall of the receiving box 10. The push-out spring 11 is used to drive the movable baffle 9 to extend into the cylinder 1. The movable baffles 9 can extend under the action of the push-out spring 11, further enhancing the disturbance effect on the material, and can retract into the receiving box 10 under certain conditions to adapt to different mixing conditions.

[0032] An electric push rod 12 is axially mounted on the outer side of the third mixing section 103. The output end of the electric push rod 12 passes through the third mixing section 103 and extends into the interior of the cylinder 1. A partition 13 is fixedly connected to the output end of the electric push rod 12. The curved surface of the partition 13 fits against the inner wall of the cylinder 1. The partition 13 is used to divide the interior of the cylinder 1 into independent working areas and idle areas. When processing small batches of materials, the electric push rod 12 pushes the partition 13 to slide inside the cylinder 1, which can reduce the space of the working area and avoid problems caused by excessive space. At the same time, when the electric push rod 12 pushes the partition 13 to slide, it will force the movable baffle 9 into the receiving box 10, preventing the movable baffle 9 from obstructing the movement of the partition 13.

[0033] The first mixing segment 101 and the second mixing segment 102 each have a limiting groove 14 on their sides. The second mixing segment 102 and the third mixing segment 103 each have a limiting ring 15 fixedly connected to their sides, which slides within the limiting groove 14. The limiting ring 15 of the second mixing segment 102 is embedded in the limiting groove 14 of the first mixing segment 101, and the limiting ring 15 of the third mixing segment 103 is embedded in the limiting groove 14 of the second mixing segment 102. The cooperation of the limiting groove 14 and the limiting ring 15 ensures the stability and coaxiality of each mixing segment during splicing and rotation, preventing relative displacement between the segments.

[0034] Working principle:

[0035] Preparation stage: Based on the batch size and characteristics of the materials to be mixed, determine the required operating area and the mixing sections to be operated. If only the first mixing section 101 needs to be operated, start the electric push rod 12 to push the partition 13 to the junction of the first mixing section 101 and the second mixing section 102. At this time, the interior of the first mixing section 101 is the operating area, and the second and third mixing sections 103 are idle areas. The partition 13 compresses the movable baffle 9 at the corresponding position in the second mixing section 102 into the receiving box 10, and the spring 11 is compressed. If the first and second mixing sections 102 need to operate together, push the partition 13 to the connection between the second and third mixing sections 103, so that the interior of the first and second mixing sections 102 is the operating area, and the third mixing section 103 is the idle area. The partition 13 compresses the movable baffle 9 at the corresponding position in the third mixing section 103 into the receiving box 10.

[0036] Feeding stage: The materials to be mixed are added into the designated working area through the feed inlet 7 on the first mixing section 101, and then the sealing cover of the feed inlet 7 is closed to ensure the sealing of the mixing process.

[0037] Mixing stage: Adjust the corresponding linkage component 5 according to the determined operating mixing section. If only the first mixing section 101 is operating, rotate the lever 504 of the linkage component 5 between the first mixing section 101 and the second mixing section 102 to the other side of the top sleeve 507, so that the moving gear ring 502 disengages from the fixed gear ring 501, and the second mixing section 102 loses power; start the rotary motor 402, drive the gear 403 to drive the gear ring 401 to rotate, and then drive the first mixing section 101 to rotate. The fixed baffle 6 in the first mixing section 101 agitates and mixes the material. If the first and second mixing sections 102 operate together, the lever 504 of the linkage component 5 between the first mixing section 101 and the second mixing section 102 is rotated to one side of the top sleeve 507, so that the moving gear ring 502 meshes with the fixed gear ring 501. At the same time, the lever 504 of the linkage component 5 between the second mixing section 102 and the third mixing section 103 is rotated to the other side of the top sleeve 507, so that the third mixing section 103 loses power. The rotary motor 402 is started, the first mixing section 101 rotates, and the linkage component 5 drives the second mixing section 102 to rotate synchronously. The fixed baffle 6 of the first mixing section 101 and the movable baffle 9 in the second mixing section 102 together agitate and mix the materials.

[0038] Discharge stage: After mixing is completed, turn off the rotary motor 402. After the mixing section stops rotating, open the discharge port 8 on the first mixing section 101 to take out the mixed material.

[0039] In the description of this specification, references to terms such as "an embodiment," "example," "specific example," etc., indicate that a specific feature, structure, material, or characteristic described in connection with that embodiment or example is included in at least one embodiment or example of the present invention. In this specification, the illustrative expressions of the above terms do not necessarily refer to the same embodiment or example. Furthermore, the specific features, structures, materials, or characteristics described may be combined in any suitable manner in one or more embodiments or examples.

[0040] The foregoing has shown and described the basic principles, main features, and advantages of this utility model. Those skilled in the art should understand that this utility model is not limited to the above embodiments. The embodiments and descriptions in the specification are merely illustrative of the principles of this utility model. Various changes and modifications can be made to this utility model without departing from its spirit and scope, and all such changes and modifications fall within the scope of the claimed utility model.

Claims

1. A mixer for pharmaceutical production, characterized in that, The device includes a cylindrical body (1) and a mounting frame (2) for supporting the cylindrical body (1). Support columns (3) are symmetrically fixedly connected to the mounting frame (2). The two support columns (3) are rotatably connected to the two ends of the cylindrical body (1) respectively. A drive assembly (4) for driving the cylindrical body (1) to rotate is provided on the mounting frame (2). The cylindrical body (1) is formed by splicing together a first mixing section (101), a second mixing section (102) and a third mixing section (103). A linkage assembly (5) for adjusting the relative rotation speed of each section is provided between the first mixing section (101) and the second mixing section (102) and between the second mixing section (102) and the third mixing section (103).

2. The mixer for pharmaceutical production according to claim 1, characterized in that, The inner wall of the first mixing section (101) is fixedly connected with several fixed baffles (6), and the first mixing section (101) is provided with an inlet (7) and an outlet (8). The inner walls of the second mixing section (102) and the third mixing section (103) are provided with several movable baffles (9), and the fixed baffles (6) and the movable baffles (9) are arranged in a circular array.

3. The mixer for pharmaceutical production according to claim 2, characterized in that, The second mixing section (102) and the third mixing section (103) are each provided with the same number of receiving boxes (10) as the movable spoilers (9). The interior of the receiving box (10) is connected to the cylinder (1). The movable spoilers (9) are slidably installed inside the receiving box (10). A push-out spring (11) is fixedly installed between the end of the movable spoiler (9) and the inner wall of the receiving box (10). The push-out spring (11) is used to drive the movable spoiler (9) to extend into the cylinder (1).

4. The mixer for pharmaceutical production according to claim 3, characterized in that, An electric push rod (12) is provided on the outer axial direction of the third mixing section (103). The output end of the electric push rod (12) passes through the third mixing section (103) and extends into the interior of the cylinder (1). A partition (13) is fixedly connected to the output end of the electric push rod (12). The curved surface of the partition (13) fits against the inner wall of the cylinder (1). The partition (13) is used to divide the interior of the cylinder (1) into independent working areas and idle areas. When the electric push rod (12) pushes the partition (13) to slide inside the cylinder (1), it will compress the movable baffle (9) into the receiving box (10).

5. The mixer for pharmaceutical production according to claim 4, characterized in that, The first mixing section (101) and the second mixing section (102) each have a limiting groove (14) on their sides. The second mixing section (102) and the third mixing section (103) each have a limiting ring (15) that slides with the limiting groove (14) on their sides. The limiting ring (15) of the second mixing section (102) is embedded in the limiting groove (14) of the first mixing section (101), and the limiting ring (15) of the third mixing section (103) is embedded in the limiting groove (14) of the second mixing section (102).

6. The mixer for pharmaceutical production according to claim 5, characterized in that, The linkage component (5) includes a fixed toothed ring (501) and a movable toothed ring (502). The movable toothed ring (502) is slidably sleeved on the end of the second mixing section (102), and the movable toothed ring (502) is keyed to the second mixing section (102). The fixed toothed ring (501) is fixedly installed on the end of the first mixing section (101) and the third mixing section (103) near the end of the second mixing section (102).

7. The mixer for pharmaceutical production according to claim 6, characterized in that, The linkage component (5) further includes a rotating shaft (503) fixedly installed on the mounting bracket (2). The rotating shaft (503) is vertically arranged, and a lever (504) is rotatably connected to the rotating shaft (503). An annular groove (505) is provided on the movable gear ring (502), and one end of the lever (504) extends into the interior of the annular groove (505). A fixing post (506) is fixedly installed on the mounting bracket (2). The fixing post (506) and the rotating shaft (503) are arranged parallel to each other. A top sleeve (507) is fitted on the top of the fixing post (506), and a lifting spring (507) is provided inside the top sleeve (507). 08), the two ends of the lifting spring (508) are respectively connected to the top of the fixed pile (506) and the top of the inner wall of the top sleeve (507). When the end of the lever (504) away from the moving toothed ring (502) is located on one side of the top sleeve (507), the moving toothed ring (502) and the fixed toothed ring (501) are in a meshing state. When the end of the lever (504) away from the moving toothed ring (502) is located on the other side of the top sleeve (507), the moving toothed ring (502) and the fixed toothed ring (501) are disengaged. When the lifting spring (508) is in a compressed state, the top of the top sleeve (507) is lower than the height of the lever (504).

8. The mixer for pharmaceutical production according to claim 7, characterized in that, The drive assembly (4) includes a gear ring (401) fixedly sleeved on the first mixing section (101), a rotary motor (402) fixedly mounted on the mounting bracket (2), and a drive tooth (403) fixedly connected to the output end of the rotary motor (402), the drive tooth (403) meshing with the gear ring (401).

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