A functional box for photothermal test strip detection and a portable infrared thermal imaging tool

Abstract

A kind of functional box of photothermal test strip detection and portable infrared thermal imaging tool;Functional box, comprising: cover, base, test strip placement table, moving drive mechanism and laser;Test strip placement table, moving drive mechanism and laser are respectively arranged in the functional area of base;Cover is detachably mounted on base, and covers functional area;Test strip placement table is used to place photothermal test strip;The output end of laser is towards test strip placement table, for irradiating the detection area of photothermal test strip;The output end of moving drive mechanism is connected to laser, for driving laser to move, so that the output end of laser moves to align the detection area of photothermal test strip;Cover is provided with detection port towards test strip placement table, and detection port is used to accommodate the detection end of hand-held infrared thermal imager.This scheme solves the problem that existing infrared thermal imaging equipment is large in structure and inconvenient to carry.

Description

Technical Field

[0001] This utility model relates to the field of infrared thermal imagers, and in particular to a functional box for photothermal test strip detection and a portable infrared thermal imaging tool. Background Technology

[0002] Lateral-flow immunochromatographic test strips have become a core technology for point-of-care testing (PoC) due to their advantages of speed, low cost, and portability. However, traditional colloidal gold test strips can only perform qualitative analysis and have limited sensitivity, especially in complex matrices where they struggle to detect ultra-low concentrations of target substances (such as infectious disease antigens and trace amounts of drugs). Although fluorescent test strips have improved sensitivity through fluorescence quantification, they still cannot meet the needs of clinical trace detection. In recent years, chemiluminescent test strips enhanced by nanozyme catalysis and surface-enhanced Raman test strips have significantly improved sensitivity through signal amplification strategies. However, the former relies on enzyme activity stability, and the latter requires an expensive large Raman spectrometer, making it difficult to meet the portability and cost requirements for PoC. To address the contradiction between sensitivity and portability, test strips utilize the photothermal effect of noble metal nanoparticles combined with infrared thermal imaging to achieve highly sensitive quantitative detection. However, the difference coefficient is significantly affected by manual operation, and existing thermal imaging modules are bulky and expensive. Although the development of integrated thermal contrast amplification readers has partially solved the reproducibility problem, device miniaturization and cost control remain bottlenecks. Utility Model Content

[0003] The purpose of this utility model is to propose a functional box for photothermal test strip detection. It can place photothermal test strips on the test strip placement platform of the base, adjust the horizontal position of the laser through a moving drive mechanism, and then install the outer cover on the base. The detection end of a handheld infrared thermal imager is fixed at the detection port of the outer cover. The combination of the handheld infrared thermal imager and the functional box allows for simple and quick acquisition of detection results.

[0004] This utility model also proposes a portable infrared thermal imaging tool, which is equipped with a handheld infrared thermal imager and the aforementioned functional box.

[0005] To achieve this objective, the present invention adopts the following technical solution:

[0006] A functional box for photothermal test strip detection includes: an outer cover, a base, a test strip placement platform, a moving drive mechanism, and a laser;

[0007] The test strip placement platform, the moving drive mechanism, and the laser are respectively located in the functional area of ​​the base; the outer cover is detachably installed on the base and covers the functional area;

[0008] The test strip placement platform is used to place photothermal test strips; the output end of the laser faces the test strip placement platform and is used to irradiate the detection area of ​​the photothermal test strip; the output end of the moving drive mechanism is connected to the laser and is used to drive the laser to move, so that the output end of the laser moves to align with the detection area of ​​the photothermal test strip.

[0009] The outer cover has a detection port facing the test strip placement platform, and the detection port is used to accommodate the detection end of a handheld infrared thermal imager.

[0010] Optimally, the outer cover is provided with a fixed inclined surface, and the fixed inclined surface is provided with the detection port; the fixed inclined surface is used to contact the plane of the handheld infrared thermal imager.

[0011] Optimally, the photothermal test strip is provided with a backing surface and a support surface; the backing surface and the support surface extend at an angle, and the lower end of the backing surface is connected to the lower end of the support surface, forming an L-shaped groove between them for accommodating the photothermal test strip.

[0012] Ideally, the angle between the back surface and the support surface is 90°.

[0013] Optimally, the moving drive mechanism includes: a screw, a moving base, and a rotary driver;

[0014] The laser is mounted on the movable base; the movable base has a threaded hole, and the screw is threaded into the threaded hole; the rotation driver is disposed on the base, and the output end of the rotation driver is connected to the screw to drive the screw to rotate, thereby causing the movable base to move linearly and thus moving the laser.

[0015] Alternatively, the moving drive mechanism may further include: a guide rail;

[0016] The guide rail is mounted on the base, and the movable seat is movably mounted on the guide rail, and the movable seat moves along the extension direction of the guide rail.

[0017] Alternatively, the moving drive mechanism may further include: a drive base;

[0018] The drive seat is mounted on the base, and the rotation driver is mounted on the drive seat;

[0019] At least two of the base, drive seat, guide rail, and test strip placement platform are integrated as a single unit.

[0020] Optimally, it may also include: a battery;

[0021] The battery is disposed on the base; the battery is electrically connected to the laser and the motion drive mechanism, and is used to supply power to the laser and the motion drive mechanism.

[0022] A portable infrared thermal imaging tool includes: a handheld infrared thermal imager and a functional box for detecting photothermal test strips as described above;

[0023] The detection end of the handheld infrared thermal imager is located at the detection port.

[0024] Optimally, the handheld infrared thermal imager is a mobile terminal; the mobile terminal is one of a mobile phone, a tablet computer, and a digital camera;

[0025] The handheld infrared thermal imager is communicatively connected to the mobile drive mechanism and / or the laser.

[0026] Compared with the prior art, one of the above technical solutions has the following beneficial effects:

[0027] This solution provides a functional box for photothermal test strip detection. It can place photothermal test strips on the test strip placement platform of the base, adjust the horizontal position of the laser through a moving drive mechanism, and then install the outer cover on the base. The detection end of the handheld infrared thermal imager is fixed in the detection port of the outer cover. The combination of the handheld infrared thermal imager and the functional box allows for simple and quick acquisition of detection results, solving the problem that existing infrared thermal imaging equipment is bulky and inconvenient to carry. Attached Figure Description

[0028] Figure 1 This is a schematic diagram of one embodiment of a portable infrared thermal imaging tool;

[0029] Figure 2 This is an exploded view of the structure of one embodiment of a portable infrared thermal imaging tool;

[0030] Figure 3 yes Figure 2 Enlarged view of section A in the middle;

[0031] Figure 4 This is a structural schematic diagram of one embodiment of the functional box.

[0032] in:

[0033] 1. Outer cover; 2. Base; 3. Test strip placement platform; 4. Motion drive mechanism; 5. Laser; 6. Battery; 10. Handheld infrared thermal imager; 11. Detection port; 12. Fixed inclined surface; 30. Photothermal test strip; 31. Backrest; 32. Support surface; 33. L-shaped groove; 301. Detection area; 41. Screw; 42. Motion seat; 43. Rotary driver; 44. Guide rail; 45. Drive seat; 421. Threaded hole. Detailed Implementation

[0034] The embodiments of this utility model are described in detail below. Examples of these embodiments are shown in the accompanying drawings, wherein the same or similar reference numerals denote the same or similar elements or elements having the same or similar functions throughout. The embodiments described below with reference to the accompanying drawings are exemplary and are only used to explain this utility model, and should not be construed as limiting this utility model.

[0035] In the description of this utility model, it should be understood that the terms "center," "longitudinal," "transverse," "length," "width," "thickness," "upper," "lower," "left," "right," "front," "rear," "vertical," "horizontal," "top," "bottom," "inner," "outer," "inner side," "outer side," "inner end," "outer end," "axial," "radial," and "circumferential," etc., indicating the orientation or positional relationship shown in the accompanying drawings, are only for the convenience of describing this utility model and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of this utility model. Furthermore, features defined with "first" and "second" may explicitly or implicitly include one or more of these features, used to distinguish descriptive features, without any order or emphasis. In the description of this utility model, unless otherwise stated, "multiple" means two or more.

[0036] like Figure 1-4 A functional box for photothermal test strip detection includes: an outer cover 1, a base 2, a test strip placement platform 3, a moving drive mechanism 4, and a laser 5;

[0037] The test strip placement platform 3, the moving drive mechanism 4, and the laser 5 are respectively disposed in the functional area 21 of the base 2; the outer cover 1 is detachably installed on the base 2 and covers the functional area 21.

[0038] The test strip placement platform 3 is used to place the photothermal test strip 30; the output end of the laser 5 faces the test strip placement platform 3 and is used to irradiate the detection area 301 of the photothermal test strip 30; the output end of the moving drive mechanism 4 is connected to the laser 5 and is used to drive the laser 5 to move, so that the output end of the laser 5 moves to align with the detection area 301 of the photothermal test strip 30.

[0039] The outer cover 1 is provided with a detection port 11 facing the test strip placement platform 3, and the detection port 11 is used to accommodate the detection end of the handheld infrared thermal imager 10.

[0040] This solution provides a functional box for photothermal test strip detection. It can place photothermal test strips 30 on the test strip placement platform 3 of the base 2, and adjust the horizontal position of the laser 5 through the moving drive mechanism 4. After the outer cover 1 is installed on the base 2, the detection end of the handheld infrared thermal imager 10 is fixed in the detection port 11 of the outer cover 1. The combination of the handheld infrared thermal imager 10 and the functional box allows for simple and quick acquisition of detection results, solving the problem that existing infrared thermal imaging equipment is bulky and inconvenient to carry.

[0041] Specifically, the outer cover 1 is installed on the base 2, which can cover the functional area 21 of the base 2, thereby separating the functional area 21 from the outside. This not only avoids the functional area 21 being affected by the external environment during the detection, but also provides a dark environment for the functional area 21, making the imaging more obvious. The functional area 21 is equipped with a test strip placement platform 3, a moving drive mechanism 4, and a laser 5. The test strip placement platform 3 is used to place the photothermal test strip 30. With the outer cover 1 open, the photothermal test strip 30 can be placed on the test strip placement platform 3, with the detection area 301 of the photothermal test strip 30 facing the detection port 11. However, the placement position of the photothermal test strip 30 may differ from the preset placement position. Therefore, the moving drive mechanism 4 can be activated. The output end of the moving drive mechanism 4 is movable, which can drive the laser 5 to move, so that the output end of the laser 5 moves to align with the detection area 301 of the photothermal test strip 30. After the test strip placement platform 3, the moving drive mechanism 4, and the laser 5 are set up, the outer cover 1 can be installed on the base 2, covering the functional area 21. Then, the handheld infrared thermal imager 10 is installed on the outer cover 1, with its detection end positioned at the detection port 11. This means the main body of the handheld infrared thermal imager 10 covers the cutout at the detection port 11, creating a completely dark environment for the functional area 21. At this point, the laser 5 and the handheld infrared thermal imager 10 can be activated. The laser 5 precisely irradiates the detection area 301 of the photothermal test strip 30 to excite the photothermal material. The handheld infrared thermal imager 10 focuses on the surface of the photothermal test strip 30 in real time, receiving thermal radiation and converting it into an electrical signal. After amplification and digital processing, a temperature distribution matrix is ​​generated, recording the temperature change (ΔT) before and after laser irradiation, and plotting a time-temperature curve. Thus, the functional box of this solution can be used in conjunction with the handheld infrared thermal imager 10, offering advantages such as small size, fast detection, and portability, solving the problem of the large and inconvenient structure of existing infrared thermal imaging equipment.

[0042] Optimally, the outer cover 1 is provided with a fixed inclined surface 12, and the fixed inclined surface 12 is provided with the detection port 11; the fixed inclined surface 12 is used to contact the plane of the handheld infrared thermal imager 10.

[0043] The fixed inclined surface 12 is used to place the handheld infrared thermal imager 10. The side of the handheld infrared thermal imager 10 with the detection end can be attached to the fixed inclined surface 12, and the detection end of the handheld infrared thermal imager 10 is placed in the detection port 11. The detection end can be snapped into the detection port 11, so that the side of the handheld infrared thermal imager 10 contacts the fixed inclined surface 12. The fixed inclined surface 12 can provide support for the handheld infrared thermal imager 10, keep the handheld infrared thermal imager 10 in an inclined state, thereby ensuring that the angle and position of the handheld infrared thermal imager 10 remain unchanged and improving detection stability.

[0044] Optimally, the photothermal test strip 30 is provided with a backing surface 31 and a supporting surface 32; the backing surface 31 and the supporting surface 32 extend at an angle, and the lower end of the backing surface 31 is connected to the lower end of the supporting surface 32, forming an L-shaped groove 33 between them for accommodating the photothermal test strip 30.

[0045] The lower end of the back surface 31 is connected to the lower end of the support surface 32. The upper end of the back surface 31 and the upper end of the support surface 32 are inclined, forming an L-shaped groove 33 between them. The photothermal test strip 30 can be directly placed in the L-shaped groove 33. Based on the inclined extension of the back surface 31 and the support surface 32, the L-shaped groove 33 uses the inclined support surface 32 to support the bottom surface of the photothermal test strip 30. The L-shaped groove 33 uses the inclined back surface 31 to support the back surface of the photothermal test strip 30, so that the detection area 301 of the photothermal test strip 30 can be kept inclined and facing the detection port 11. The L-shaped groove 33 mainly supports the bottom surface, back surface and the transition position of the two sides of the photothermal test strip 30, so that the photothermal test strip 30 is not easy to tilt forward.

[0046] Optimally, the included angle between the back surface 31 and the support surface 32 is 90°.

[0047] like Figure 3 As is generally known, the bottom and back surfaces of the photothermal test strip 30 are at a 90° angle. Therefore, when the angle between the back surface 31 and the support surface 32 is 90°, the bottom surface of the photothermal test strip 30 can make planar contact with the support surface 32, and the back surface of the photothermal test strip 30 can make planar contact with the back surface 31. The photothermal test strip 30 can be positioned at the required angle, so that the detection area 301 is located at the optimal irradiation angle of the laser 5 and the optimal detection angle of the handheld infrared thermal imager 10.

[0048] The moving drive mechanism 4 is a known mechanism with a driving and moving function, such as a cylinder, a hydraulic cylinder, a conveyor belt structure, a combination of gears and gear chains, a combination of gears and racks, etc., as long as it can drive the laser 5 to move.

[0049] Optimally, the moving drive mechanism 4 includes: a screw 41, a moving base 42, and a rotary driver 43;

[0050] The laser 5 is mounted on the movable base 42; the movable base 42 is provided with a threaded hole 421, and the screw 41 is threaded into the threaded hole 421; the rotation driver 43 is disposed on the base 2, and the output end of the rotation driver 43 is connected to the screw 41 to drive the screw 41 to rotate, thereby driving the movable base 42 to move linearly and thus moving the laser 5.

[0051] The screw 41 is threaded into the threaded hole 421 of the movable seat 42; the rotary driver 43 is located on the movable seat 42; the rotary driver 43 can drive the screw 41 to rotate, and the rotation of the screw 41 will drive the movable seat 42 to move linearly, so that the laser 5 of the movable seat 42 moves relative to the base 2, the laser 5 can be adjusted to the target position, and finally the output end of the laser 5 can be adjusted to face the detection area 301 of the photothermal test strip 30.

[0052] The rotary actuator 43 is a known mechanism for driving rotation, such as a motor or a combination of a motor and a reducer, as long as it drives the screw 41 to rotate.

[0053] Alternatively, the moving drive mechanism 4 may further include: a guide rail 44;

[0054] The guide rail 44 is mounted on the base 2, and the movable seat 42 is movably mounted on the guide rail 44. The movable seat 42 moves along the extension direction of the guide rail 44.

[0055] The guide rail 44 is mounted on the base 2 and extends along the moving direction of the movable seat 42. The rotation of the screw 41 will drive the movable seat 42 to move linearly. Since the movable seat 42 is mounted on the guide rail 44, and the movable seat 42 moves along the extending direction of the guide rail 44, the laser 5 can move along the extending direction of the guide rail 44. In this way, the guide rail 44 can improve the stability and smoothness of the movement of the laser 5.

[0056] Alternatively, the moving drive mechanism 4 may further include: a drive base 45;

[0057] The drive seat 45 is mounted on the base 2, and the rotation driver 43 is mounted on the drive seat 45;

[0058] At least two of the base 2, drive seat 45, guide rail 44 and test strip placement platform 3 are integrated into one piece.

[0059] The drive seat 45 is used to fix the rotary actuator 43 to the base 2. The functional box has multiple fixed structures, such as the base 2, drive seat 45, guide rail 44, and test strip placement platform 3. At least two of the four can be designed as an integral combination as needed, that is, any two adjacent components are formed simultaneously during molding. For example, the drive seat 45, guide rail 44, and test strip placement platform 3 can be integrally molded on the base 2, with no connection gap between them. This also simplifies the installation process of the test strip placement platform 3 and the moving drive mechanism 4 on the base 2. It is only necessary to directly install the rotary actuator 43 and the moving seat 42 on the base 2.

[0060] Optimally, it also includes: battery 6;

[0061] The battery 6 is disposed on the base 2; the battery 6 is electrically connected to the laser 5 and the moving drive mechanism 4, and is used to supply power to the laser 5 and the moving drive mechanism 4.

[0062] The functional box of this solution preferably uses battery 6 to directly power laser 5 and moving drive mechanism 4. Since the handheld infrared thermal imager 10 has its own power supply, the handheld infrared thermal imager 10 can be combined with the functional box without the need for an external power supply. It can be ready to detect at any time, solving the problem that the existing infrared thermal imaging equipment is bulky and inconvenient to carry.

[0063] A portable infrared thermal imaging tool includes: a handheld infrared thermal imager 10 and a functional box for detecting photothermal test strips as described above;

[0064] The detection end of the handheld infrared thermal imager 10 is located at the detection port 11.

[0065] Alternatively, the handheld infrared thermal imager 10 can be a mobile terminal; the mobile terminal can be one of a mobile phone, a tablet computer, and a digital camera.

[0066] The handheld infrared thermal imager 10 is communicatively connected to the mobile drive mechanism 4 and / or the laser 5.

[0067] The handheld infrared thermal imager 10 is preferably a mobile phone, tablet computer, or digital camera. These are common electronic devices in daily life, requiring only the infrared thermal imaging sensor to be externally mounted or internally integrated, and / or an additional infrared thermal imaging lens. Infrared thermal imaging mobile phones, tablet computers, and digital cameras are currently available mobile terminals, meeting the detection requirements in both software and hardware. Especially in terms of computing power, most mobile phones and tablet computers have chips that can meet the computational requirements. In practical applications, a tailored accompanying APP can be developed to automate laser irradiation, temperature acquisition, and data analysis. Users only need to load the photothermal test strip 30, launch the APP, and obtain the results to complete the detection, significantly reducing the difficulty of detection.

[0068] The communication connection method here refers to the communication established between connected devices through signal transmission and interaction, which can be divided into wired connection and wireless connection; wired connection is such as conventional data cable connection; wireless connection is such as conventional WiFi, Bluetooth, infrared, NFC, etc.

[0069] Although embodiments of the present invention have been shown and described, those skilled in the art will understand that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the present invention, the scope of which is defined by the claims and their equivalents.

Claims

1. A functional box for photothermal test strip detection, characterized in that, include: Outer casing, base, test strip placement platform, moving drive mechanism, and laser; The test strip placement platform, the moving drive mechanism, and the laser are respectively located in the functional area of ​​the base; the outer cover is detachably installed on the base and covers the functional area; The test strip placement platform is used to place photothermal test strips; the output end of the laser is oriented towards the test strip placement platform and is used to irradiate the detection area of ​​the photothermal test strip. The output end of the moving drive mechanism is connected to the laser and is used to drive the laser to move so that the output end of the laser moves to the detection area aligned with the photothermal test strip; The outer cover has a detection port facing the test strip placement platform, and the detection port is used to accommodate the detection end of a handheld infrared thermal imager.

2. The functional box for photothermal test strip detection according to claim 1, characterized in that, The outer cover has a fixed inclined surface, and the fixed inclined surface has the detection port; the fixed inclined surface is used to contact the plane of the handheld infrared thermal imager.

3. The functional box for photothermal test strip detection according to claim 1, characterized in that, The photothermal test strip is provided with a backing surface and a supporting surface; the backing surface and the supporting surface extend at an angle, and the lower end of the backing surface is connected to the lower end of the supporting surface, forming an L-shaped groove between them for accommodating the photothermal test strip.

4. The functional box for photothermal test strip detection according to claim 3, characterized in that, The angle between the backrest and the support surface is 90°.

5. The functional box for photothermal test strip detection according to claim 1, characterized in that, The moving drive mechanism includes: a screw, a moving base, and a rotary driver; The laser is mounted on the movable base; the movable base has a threaded hole, and the screw is threaded into the threaded hole; the rotation driver is disposed on the base, and the output end of the rotation driver is connected to the screw to drive the screw to rotate, thereby causing the movable base to move linearly and thus moving the laser.

6. The functional box for photothermal test strip detection according to claim 5, characterized in that, The moving drive mechanism further includes: a guide rail; The guide rail is mounted on the base, and the movable seat is movably mounted on the guide rail, and the movable seat moves along the extension direction of the guide rail.

7. The functional box for photothermal test strip detection according to claim 6, characterized in that, The moving drive mechanism further includes: a drive base; The drive seat is mounted on the base, and the rotation driver is mounted on the drive seat; At least two of the base, drive seat, guide rail, and test strip placement platform are integrated as a single unit.

8. The functional box for photothermal test strip detection according to claim 1, characterized in that, Also includes: Battery; The battery is disposed on the base; the battery is electrically connected to the laser and the motion drive mechanism, and is used to supply power to the laser and the motion drive mechanism.

9. A portable infrared thermal imaging tool, characterized in that, include: A handheld infrared thermal imager and a functional box for photothermal test strip detection as described in any one of claims 1-8; The detection end of the handheld infrared thermal imager is located at the detection port.

10. A portable infrared thermal imaging tool according to claim 9, characterized in that, The handheld infrared thermal imager is a mobile terminal; the mobile terminal is one of a mobile phone, tablet computer, and digital camera. The handheld infrared thermal imager is communicatively connected to the mobile drive mechanism and / or the laser.

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