liquid chromatograph

Abstract

This application discloses a liquid chromatograph, belonging to the field of chromatograph technology. It includes a liquid chromatograph body with a placement groove on the top. Two sets of reaction flasks are placed in the placement groove. Clamping blocks are provided on both sides of each reaction flask, and the two sets of clamping blocks are arranged opposite each other. A driving mechanism is provided on one side of each set of opposite clamping blocks. The driving mechanism includes a bracket, which is fixedly installed on one side of the liquid chromatograph body. When the reaction flask containing the reagent is placed in the placement groove, the corresponding reciprocating motor is started. The forward rotation of the reciprocating motor drives the two sets of screws to rotate. The moving blocks on the surface of the screws move closer together under the action of the threads. Simultaneously, the connecting rod drives the two sets of clamping blocks to move closer together. The V-grooves of the two sets of clamping blocks can clamp and fix reaction flasks of different diameters, effectively fixing reaction flasks of different diameters and improving practicality during use.

Description

Technical Field

[0001] This application relates to the field of chromatography technology, and more particularly to liquid chromatography. Background Technology

[0002] When testing implantable long-acting contraceptive pills (tube-shaped), whose main components include levonorgestrel and silicone rubber, the content and dissolution of the effective components in the finished product need to be detected using liquid chromatography.

[0003] Existing liquid chromatographs typically require reaction flasks of varying diameters depending on the application requirements. However, existing liquid chromatographs do not provide adequate support for securing these flasks, and their inconvenience in fixing flasks of different diameters results in limited practicality during use.

[0004] Therefore, this application provides a liquid chromatograph. Utility Model Content

[0005] To address the shortcomings of existing technologies, this application provides a liquid chromatograph that overcomes these deficiencies. The purpose is to solve the problem that existing liquid chromatographs, depending on the application requirements, typically require reaction flasks of varying diameters. Furthermore, existing liquid chromatographs are not sufficiently robust in securing reaction flasks and are not convenient for fixing reaction flasks of different diameters, resulting in low practicality during use.

[0006] To achieve the above objectives, this application provides the following technical solution: a liquid chromatograph, including a liquid chromatograph body, a placement groove on the top of the liquid chromatograph body, two sets of reaction flasks placed in the placement groove, clamping blocks on both sides of each reaction flask, and the two sets of clamping blocks facing each other, a driving mechanism on one side of each set of facing clamping blocks, the driving mechanism including a bracket, the bracket being fixedly installed on one side of the liquid chromatograph body, a reciprocating motor fixedly installed on the top of the bracket, reciprocating motors fixedly installed on both sides of the reciprocating motors, and both sets of reciprocating motors being rotatably connected to the bracket, a moving block being threadedly connected to the outer surface of the reciprocating motor, a connecting rod connecting the moving block to the corresponding clamping block, and a V-groove on the side of the clamping block near the reaction flask.

[0007] By adopting the above technical solution, the reaction bottle containing the reagent is placed in the placement slot, and the corresponding reciprocating motor is started. The forward rotation of the reciprocating motor drives the two sets of screws to rotate. The moving blocks on the surface of the screws move closer together under the action of the threads. At the same time, the connecting rod drives the two sets of clamping blocks to move closer together. The V-shaped grooves of the two sets of clamping blocks can clamp and fix reaction bottles of different sizes, effectively fixing reaction bottles of different sizes and improving the practicality during use.

[0008] As a preferred technical solution of this application, a controller is fixedly installed on one side of the liquid chromatograph body, and a pressure sensor is fixedly installed on the side of the clamping block near the reaction flask. The pressure sensor and the bracket are both electrically connected to the controller.

[0009] By adopting the above technical solution, when the clamping blocks on both sides of the reaction flask clamp it, the magnitude of the clamping force is monitored in real time by the pressure sensor and the data is fed back to the controller. The controller controls the start and stop of the reciprocating motor one according to the feedback data, thereby realizing the precise control of the clamping force of the two sets of clamping blocks on the reaction flask, and further improving the protection effect when clamping the reaction flask.

[0010] As a preferred technical solution of this application, two sets of support plates are fixedly installed at the bottom of the liquid chromatograph body, and support pads are fixedly installed at the bottom of each set of support plates. A movable plate is slidably connected between the two sets of support plates, and universal wheels are rotatably connected at the four corners of the bottom of the movable plate. An adjustment mechanism is provided above the movable plate.

[0011] By adopting the above technical solution, the liquid chromatograph body is easily moved by four sets of universal wheels in contact with the ground. When it is moved to the designated position, the adjustment mechanism drives the movable plate to move upward, so that the universal wheels leave the ground and the support pad contacts the ground, thereby improving the stability of the liquid chromatograph body during operation.

[0012] As a preferred embodiment of this application, the adjustment mechanism includes a reciprocating motor II, which is fixedly installed at the bottom of the liquid chromatograph body. Two sets of output ends of the reciprocating motor II are each fixedly equipped with a screw II. The end of the screw II away from the reciprocating motor II is rotatably connected to the support plate. The outer surface of the screw II is threaded with a screw II. A moving block II is fixedly installed at the bottom of the screw II. A connecting block I is fixedly installed at the top of the support plate. Connecting blocks II are hinged between both sets of moving blocks II and connecting blocks I.

[0013] By adopting the above technical solution, the reciprocating motor 2 drives the two sets of screws 2 to rotate, and the moving block 2 moves closer or further away under the action of the threads on the surface of the screw 2. The moving block 2 drives the adjusting rod to rotate through the connecting block 2, and the two sets of adjusting rods drive the movable plate to move up and down through the connecting block 1, thereby realizing the lifting control of the universal wheel, which facilitates the movement of the liquid chromatograph body and ensures the stability of the liquid chromatograph body during operation.

[0014] As a preferred technical solution of this application, two sets of guide blocks are fixedly installed on both sides of the movable plate, and two sets of guide grooves are opened on the opposite surfaces of the two sets of support plates, and the guide blocks are slidably connected to the sliding end of the corresponding guide groove.

[0015] By adopting the above technical solution, when the movable plate moves up and down, it drives four sets of guide blocks to slide in the corresponding guide grooves, guiding the reaction bottle as it moves up and down, thus ensuring the stability of the movable plate during displacement.

[0016] As a preferred technical solution of this application, the top of the liquid chromatograph body is provided with two sets of adjustment chambers, and the two adjacent sets of connecting rods are slidably connected in the same set of adjustment chambers.

[0017] By adopting the above technical solution, the adjustment cavity provides movement space for the connecting rod, which is beneficial to the smoothness of the connecting rod driving the clamping block to move.

[0018] As a preferred technical solution of this application, protective pads are fixedly installed on the opposite surfaces of the two sets of clamping blocks that are arranged opposite to each other.

[0019] By adopting the above technical solution, the protective pad improves the protection effect when clamping the reaction flask.

[0020] The beneficial effects of this application are:

[0021] 1. Place the reaction bottle containing the reagent into the placement slot, start the corresponding reciprocating motor, the forward rotation of the reciprocating motor drives the two sets of screws to rotate, the moving blocks on the surface of the screws to move closer together under the action of the threads, and at the same time, the connecting rod drives the two sets of clamping blocks to move closer together. The V-grooves of the two sets of clamping blocks can clamp and fix reaction bottles of different sizes, effectively fixing reaction bottles of different sizes and improving the practicality during use.

[0022] 2. When the clamping blocks on both sides of the reaction flask clamp it, the magnitude of the clamping force is monitored in real time by the pressure sensor and the data is fed back to the controller. The controller controls the start and stop of the reciprocating motor one according to the feedback data, thereby realizing the precise control of the clamping force of the two sets of clamping blocks on the reaction flask, and further improving the protection effect when clamping the reaction flask. Attached Figure Description

[0023] Figure 1 This is a schematic diagram of the overall structure of this application;

[0024] Figure 2 This is a top view of the structure of this application;

[0025] Figure 3 This is a schematic diagram of the drive mechanism structure;

[0026] Figure 4 for Figure 1 Enlarged structural diagram at point A in the middle.

[0027] In the diagram: 1. Liquid chromatograph body; 2. Placement slot; 3. Reaction flask; 4. Clamping block; 5. Drive mechanism; 501. Support; 502. Reciprocating motor one; 503. Screw one; 504. Moving block one; 505. Connecting rod; 6. V-groove; 7. Support plate; 8. Support pad; 9. Movable plate; 10. Casters; 11. Adjustment mechanism; 1101. Reciprocating motor two; 1102. Screw two; 1103. Moving block two; 1104. Connecting block one; 1105. Connecting block two; 1106. Adjusting rod; 12. Guide block; 13. Guide groove; 14. Controller; 15. Pressure sensor; 16. Adjustment chamber; 17. Protective pad. Detailed Implementation

[0028] The technical solutions of the embodiments of this application will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of this application, and not all embodiments. Based on the embodiments of this application, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of this application.

[0029] Reference Figure 1-4 A liquid chromatograph includes a liquid chromatograph body 1. A placement groove 2 is provided on the top of the liquid chromatograph body 1. Two sets of reaction flasks 3 are placed in the placement groove 2. Clamping blocks 4 are provided on both sides of each reaction flask 3, and the two sets of clamping blocks 4 are arranged opposite each other. A drive mechanism 5 is provided on one side of each set of opposite clamping blocks 4. The drive mechanism 5 includes a bracket 501, which is fixedly installed on one side of the liquid chromatograph body 1. A reciprocating motor 502 is fixedly installed on the top of the bracket 501. Reciprocating motors 502 are fixedly installed on both sides of the reciprocating motor 502. The reciprocating motor 502 is rotatably connected to the bracket 501. The outer surface of the reciprocating motor 502 is threaded with a moving block 504. The moving block 504 is connected to the corresponding clamping block 4 by a connecting rod 505. The clamping block 4 has a V-groove 6 on the side near the reaction flask 3. Two sets of support plates 7 are fixedly installed at the bottom of the liquid chromatograph body 1. Support pads 8 are fixedly installed at the bottom of the two sets of support plates 7. A movable plate 9 is slidably connected between the two sets of support plates 7. Universal wheels 10 are rotatably connected at the four corners of the bottom of the movable plate 9. An adjustment mechanism 11 is provided above the movable plate 9.

[0030] The reaction flask 3 containing the reagent is placed in the placement slot 2. The corresponding reciprocating motor 502 is started. The forward rotation of the reciprocating motor 502 drives the two sets of screws 503 to rotate. The moving blocks 504 on the surface of the screws 503 approach each other under the action of the threads. At the same time, the connecting rod 505 drives the two sets of clamping blocks 4 to approach each other. The V-grooves 6 of the two sets of clamping blocks 4 can clamp and fix the reaction flasks 3 of different sizes, effectively fixing the reaction flasks 3 of different sizes and improving the practicality during use. The four sets of universal wheels 10 are in contact with the ground, which facilitates the movement of the liquid chromatograph body 1. When it is moved to the designated position, the adjusting mechanism 11 drives the movable plate 9 to move upward, so that the universal wheels 10 leave the ground and the support pad 8 contacts the ground, improving the stability of the liquid chromatograph body 1 during operation.

[0031] Reference Figure 1-2 , Figure 4 A controller 14 is fixedly installed on one side of the liquid chromatograph body 1. A pressure sensor 15 is fixedly installed on the side of the clamping block 4 near the reaction flask 3. The pressure sensor 15 and the bracket 501 are both electrically connected to the controller 14. The adjustment mechanism 11 includes a reciprocating motor 1101, which is fixedly installed at the bottom of the liquid chromatograph body 1. Screws 1102 are fixedly installed on both output ends of the reciprocating motor 1101. The end of the screw 1102 away from the reciprocating motor 1101 is rotatably connected to the support plate 7. The outer surface of the screw 1102 is threaded with screws 1102. A moving block 1103 is fixedly installed at the bottom of the screw 1102. A connecting block 1104 is fixedly installed at the top of the support plate 7. A connecting block 1105 is hinged between the two sets of moving blocks 1103 and the connecting block 1104.

[0032] When the clamping blocks 4 on both sides of the reaction flask 3 clamp it, the pressure sensor 15 monitors the clamping force in real time and feeds the data back to the controller 14. The controller 14 controls the start and stop of the reciprocating motor 502 according to the feedback data, thereby achieving precise control of the clamping force of the two sets of clamping blocks 4 on the reaction flask 3, further improving the protection effect when clamping the reaction flask 3. The reciprocating motor 1101 drives the two sets of screws 1102 to rotate. The moving block 1103 moves closer or further away under the action of the threads on the surface of the screws 1102. The moving block 1103 drives the adjusting rod 1106 to rotate through the connecting block 1105. The two sets of adjusting rods 1106 drive the movable plate 9 to move up and down through the connecting block 1104, thereby realizing the lifting control of the caster wheel 10, which facilitates the movement of the liquid chromatograph body 1 and ensures the stability of the liquid chromatograph body 1 during operation.

[0033] Reference Figure 2-4Two sets of guide blocks 12 are fixedly installed on both sides of the movable plate 9. Two sets of guide grooves 13 are opened on the opposite surfaces of the two sets of support plates 7, and the guide blocks 12 are slidably connected to the sliding end of the corresponding guide groove 13. Protective pads 17 are fixedly installed on the opposite surfaces of the two sets of clamping blocks 4. When the movable plate 9 moves up and down, it drives the four sets of guide blocks 12 to slide in the corresponding guide grooves 13, guiding the reaction bottle 3 when it moves up and down, ensuring the stability of the movable plate 9 when it is displaced. The protective pads 17 improve the protection effect when clamping the reaction bottle 3.

[0034] Reference Figure 1-3 The top of the liquid chromatograph body 1 has two sets of adjustment chambers 16, and two adjacent sets of connecting rods 505 are slidably connected in the same set of adjustment chambers 16; the adjustment chambers 16 provide movement space for the connecting rods 505, which is beneficial to the smooth movement of the clamping block 4 when the connecting rods 505 drive it.

[0035] Working principle: The reaction bottle 3 containing the reagent is placed in the placement slot 2. The corresponding reciprocating motor 502 is started. The forward rotation of the reciprocating motor 502 drives the two sets of screws 503 to rotate. The moving blocks 504 on the surface of the screws 503 approach each other under the action of the threads. At the same time, the connecting rod 505 drives the two sets of clamping blocks 4 to approach each other. The V-grooves 6 of the two sets of clamping blocks 4 can clamp and fix reaction bottles 3 of different sizes, effectively fixing reaction bottles 3 of different sizes and improving the practicality during use. When the clamping blocks 4 on both sides of the reaction bottle 3 clamps it, the pressure sensor 15 monitors the magnitude of the clamping force in real time and feeds the data back to the controller 14. The controller 14 controls the start and stop of the reciprocating motor 502 according to the feedback data, thereby realizing the precise control of the clamping force of the two sets of clamping blocks 4 on the reaction bottle 3, further improving the protection effect when clamping the reaction bottle 3.

[0036] The system incorporates four sets of casters 10 that contact the ground, facilitating the movement of the liquid chromatograph body 1. Once moved to the designated position, the adjusting mechanism 11 drives the movable plate 9 upward, lifting the casters 10 off the ground and bringing the support pad 8 into contact with the ground, thus improving the stability of the liquid chromatograph body 1 during operation. The reciprocating motor 1101 drives two sets of screws 1102 to rotate, causing the moving blocks 1103 to move closer or further apart under the action of the threads on the surface of the screws 1102. The moving blocks 1103 drive the adjusting rods 1106 to rotate via the connecting block 1105, and the two adjusting rods 1106 drive the movable plate 9 to move up and down via the connecting block 1104. This achieves lifting control of the casters 10, facilitating the movement of the liquid chromatograph body 1 and ensuring its stability during operation.

[0037] At the same time, when the movable plate 9 moves up and down, it drives the four sets of guide blocks 12 to slide in the corresponding guide grooves 13, which guides the reaction bottle 3 when it moves up and down, ensuring the stability of the movable plate 9 when it is displaced; the adjustment cavity 16 provides movement space for the connecting rod 505, which is conducive to the smooth movement of the clamping block 4 when the connecting rod 505 drives it.

[0038] In addition, the protective pad 17 improves the protection effect when the reaction flask 3 is clamped.

[0039] The above description is merely a preferred embodiment of this application and is not intended to limit this application. Although this application has been described in detail with reference to the foregoing embodiments, those skilled in the art can still modify the technical solutions described in the foregoing embodiments or make equivalent substitutions for some of the technical features. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of this application should be included within the protection scope of this application.

Claims

1. A liquid chromatograph, comprising a liquid chromatograph body (1), characterized in that, The top of the liquid chromatograph body (1) is provided with a placement slot (2), in which two sets of reaction flasks (3) are placed. Clamping blocks (4) are provided on both sides of each reaction flask (3), and the two sets of clamping blocks (4) are arranged opposite to each other. A driving mechanism (5) is provided on one side of each set of opposite clamping blocks (4). The driving mechanism (5) includes a bracket (501), which is fixedly installed on one side of the liquid chromatograph body (1). The top of the bracket (501) is fixed... A reciprocating motor (502) is fixedly installed on both sides of the reciprocating motor (502), and both sets of the reciprocating motors (502) are rotatably connected to the bracket (501). A moving block (504) is threadedly connected to the outer surface of the reciprocating motor (502). A connecting rod (505) is connected between the moving block (504) and the corresponding clamping block (4). A V-groove (6) is opened on the side of the clamping block (4) near the reaction bottle (3).

2. The liquid chromatograph according to claim 1, characterized in that, A controller (14) is fixedly installed on one side of the liquid chromatograph body (1), and a pressure sensor (15) is fixedly installed on the side of the clamping block (4) near the reaction flask (3). The pressure sensor (15) and the bracket (501) are both electrically connected to the controller (14).

3. The liquid chromatograph according to claim 1, characterized in that, Two sets of support plates (7) are fixedly installed at the bottom of the liquid chromatograph body (1). Support pads (8) are fixedly installed at the bottom of both sets of support plates (7). A movable plate (9) is slidably connected between the two sets of support plates (7). Universal wheels (10) are rotatably connected at the four corners of the bottom of the movable plate (9). An adjustment mechanism (11) is provided above the movable plate (9).

4. The liquid chromatograph according to claim 3, characterized in that, The adjustment mechanism (11) includes a reciprocating motor (1101), which is fixedly installed at the bottom of the liquid chromatograph body (1). Both output ends of the reciprocating motor (1101) are fixedly installed with screws (1102). The end of the screws (1102) away from the reciprocating motor (1101) is rotatably connected to the support plate (7). The outer surface of the screws (1102) is threaded with screws (1102). The bottom end of the screws (1102) is fixedly installed with a moving block (1103). The top end of the support plate (7) is fixedly installed with a connecting block (1104). Both sets of moving blocks (1103) and connecting blocks (1104) are hinged with connecting blocks (1105).

5. The liquid chromatograph according to claim 3, characterized in that, Two sets of guide blocks (12) are fixedly installed on both sides of the movable plate (9). Two sets of guide grooves (13) are opened on the opposite surfaces of the two sets of support plates (7), and the guide blocks (12) are slidably connected to the sliding end of the corresponding guide grooves (13).

6. The liquid chromatograph according to claim 1, characterized in that, The top of the liquid chromatograph body (1) is provided with two sets of adjustment chambers (16), and the two adjacent sets of connecting rods (505) are slidably connected in the same set of adjustment chambers (16).

7. The liquid chromatograph according to claim 1, characterized in that, Protective pads (17) are fixedly installed on the opposite surfaces of the two sets of clamping blocks (4) that are arranged opposite to each other.

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