A pharmaceutical chemical preparation device

Abstract

The utility model discloses a kind of pharmaceutical chemical preparation devices, it is related to pharmaceutical chemical field, including reaction kettle shell, servo motor is fixedly installed on reaction kettle shell, transmission shaft structure is fixedly installed in reaction kettle shell and on the output shaft of servo motor, transmission shaft structure is composed of transmission shaft main body, baffle ring, first limit post and second limit post, by setting transmission shaft structure on the output shaft of servo motor, adjustable paddle is set on transmission shaft structure, and adjusting fixed structure, rotating sleeve can drive gear ring rotation, using the meshing transmission of gear ring and rack, drive adjustable paddle moves along slot and accommodating groove, realize the flexible adjustment of adjustable paddle stirring length, adapt to the stirring demand of different volume, viscosity material, so as not to equip multiple sets of stirrer, reduce equipment procurement and storage cost, improve the adaptability of reaction kettle to different pharmaceutical chemical reaction working condition, guarantee material mixing uniformity and reaction effect.

Description

Technical Field

[0001] This utility model relates to the field of pharmaceutical and chemical engineering, and in particular to a pharmaceutical and chemical preparation apparatus. Background Technology

[0002] In the pharmaceutical and chemical industry, pharmaceutical preparation is a core process with extremely stringent reaction conditions. It encompasses multiple key steps, including active pharmaceutical ingredient synthesis and formulation, and the purity, efficacy, and stability of the final product are closely related to the reaction efficiency and material mixing uniformity during the preparation process. Among these, the reaction vessel, as the core reaction container in the pharmaceutical preparation process, plays a crucial role in providing a suitable environment (such as specific temperature, pressure, and stirring rate) for various chemical reactions. It is widely used in operations such as solution mixing, chemical reaction synthesis, and crystallization, and is a key piece of equipment for ensuring the quality and production efficiency of pharmaceutical products. During the operation of the reaction vessel, the stirring system is one of the core components affecting the reaction effect. Traditional reaction vessel stirring systems typically consist of a drive motor, a transmission shaft, and a fixed-size stirrer (such as a paddle or turbine stirrer). Its working principle is that the drive motor rotates the transmission shaft, which in turn causes the stirrer to agitate the materials inside the vessel, achieving thorough mixing, heat transfer, and uniform distribution of reaction products. However, in actual pharmaceutical preparation scenarios, the stirring requirements vary significantly depending on the batch and type of pharmaceutical reaction: for example, when synthesizing small batches of high-viscosity active pharmaceutical ingredients, the stirrer needs to cover a concentrated area to ensure local shear force; while when preparing large batches of low-viscosity formulations, the stirrer needs to cover a wider area to improve overall mixing efficiency.

[0003] The core limitation of traditional agitators lies in their fixed and non-adjustable stirring length (i.e., the stirring diameter formed when the agitator rotates). This defect results in poor adaptability of the reactor to different operating conditions: when the volume or viscosity of the processed material changes, or when the type of reaction is changed, the agitator with a fixed stirring diameter cannot match the new stirring requirements. If the stirring diameter is too large, excessive turbulence may be generated in a small volume of material, disrupting the reaction equilibrium; if the stirring diameter is too small, it cannot effectively cover the material in the reactor, leading to uneven mixing in certain areas, resulting in incomplete reaction and decreased product purity. To cope with different operating conditions, companies often need to equip themselves with multiple agitators of different sizes, increasing equipment procurement and storage costs. Utility Model Content

[0004] The main objective of this invention is to provide a pharmaceutical and chemical preparation apparatus that can effectively solve the problems in the background art.

[0005] To achieve the above objectives, the technical solution adopted by this utility model is as follows: A pharmaceutical chemical preparation apparatus includes a reaction vessel shell. A servo motor is fixedly installed on the reaction vessel shell. A transmission shaft structure is fixedly installed inside the reaction vessel shell and on the output shaft of the servo motor. The transmission shaft structure consists of a transmission shaft body, a retaining ring, a first limiting post, and a second limiting post. The retaining ring, the first limiting post, and the second limiting post are all fixedly sleeved on the transmission shaft body. The second limiting post is located below the retaining ring, and the first limiting post is located between the retaining ring and the second limiting post. Two adjustable blades are symmetrically and movably inserted on the first and second limiting posts. The adjustable blades consist of a blade plate, a guide plate, and a rack. The guide plate and the rack are symmetrically and fixedly installed on the inner end of the blade plate. An adjustment and fixing structure is rotatably installed inside the first limiting post. The adjustment and fixing structure consists of a gear ring, a sleeve, an internally threaded cylinder, and a bolt. The gear ring meshes with the rack. The sleeve is fixedly installed on the upper end of the gear ring. The internally threaded cylinder is fixedly inserted into the sleeve, and the bolt is installed inside the internally threaded cylinder.

[0006] Preferably, the first limiting post on the transmission shaft structure has a receiving groove, the lower end of the first limiting post has a first shaft hole, and the upper end of the first limiting post has a through hole. The receiving groove is connected to the first shaft hole and the through hole. The first limiting post is fixedly sleeved on the transmission shaft body through the first shaft hole. The transmission shaft body is fixedly installed on the output shaft of the servo motor.

[0007] Preferably, the second limiting post on the transmission shaft structure has a second shaft hole, and the second limiting post is fixedly sleeved on the transmission shaft body through the second shaft hole. Two slots are symmetrically opened on the second limiting post on both sides of the second shaft hole.

[0008] Preferably, the blade on the adjustable blade is located on one side of the drive shaft structure, the guide plate is movably inserted into a slot opened on the second limiting post, and the rack is movably inserted into a receiving groove opened on the first limiting post.

[0009] Preferably, the toothed ring on the adjusting and fixing structure is rotatably installed in the receiving groove opened on the first limiting post, the sleeve passes upward through the through hole opened on the first limiting post, and the sleeve is simultaneously located below the retaining ring, and the inner end of the bolt abuts against the transmission shaft body.

[0010] Compared with the prior art, the present invention has the following beneficial effects: By setting a transmission shaft structure consisting of a transmission shaft body, a retaining ring, a first limiting post, and a second limiting post on the output shaft of the servo motor, and setting an adjustable blade consisting of a paddle plate, a guide plate, and a rack on the transmission shaft structure, as well as an adjustment and fixing structure consisting of a gear ring, a sleeve, an internal threaded cylinder, and bolts, rotating the sleeve can drive the gear ring to rotate. Utilizing the meshing transmission between the gear ring and the rack, the adjustable blade is driven to move along the slot and the receiving groove, realizing flexible adjustment of the adjustable blade stirring length to adapt to the stirring needs of materials with different volumes and viscosities. This eliminates the need for multiple sets of agitators, reduces equipment procurement and storage costs, improves the adaptability of the reactor to different pharmaceutical and chemical reaction conditions, and ensures the uniformity of material mixing and reaction effect. Attached Figure Description

[0011] Figure 1 This is a schematic diagram of the cross-section of the reactor shell of this utility model; Figure 2 This is a schematic diagram of the transmission shaft structure of this utility model; Figure 3 This is a schematic diagram showing the positional relationship between the adjustable blade and the first and second limiting posts of this utility model. Figure 4 This is a schematic diagram of the adjusting and fixing structure of this utility model.

[0012] In the diagram: 1. Reactor shell; 2. Servo motor; 3. Drive shaft structure; 4. Adjustable blade; 5. Adjustment and fixing structure; 6. Bolt; 7. Drive shaft body; 8. Retaining ring; 9. First limiting post; 10. Receiving groove; 11. Through hole; 12. First shaft hole; 13. Second limiting post; 14. Second shaft hole; 15. Slot; 16. Paddle plate; 17. Guide plate; 18. Rack; 19. Gear ring; 20. Sleeve; 21. Internal threaded cylinder. Detailed Implementation

[0013] To make the technical means, creative features, objectives and effects of this utility model easier to understand, the present utility model will be further described below in conjunction with specific embodiments.

[0014] Please see Figure 1 , Figure 2 , Figure 3 , Figure 4As shown, a pharmaceutical chemical preparation apparatus includes a reaction vessel shell 1. A servo motor 2 is fixedly mounted on the reaction vessel shell 1. A transmission shaft structure 3 is fixedly mounted inside the reaction vessel shell 1 and on the output shaft of the servo motor 2. The transmission shaft structure 3 consists of a transmission shaft body 7, a retaining ring 8, a first limiting post 9, and a second limiting post 13. The retaining ring 8, the first limiting post 9, and the second limiting post 13 are all fixedly sleeved on the transmission shaft body 7. The second limiting post 13 is located below the retaining ring 8. The first limiting post 9 is located between the retaining ring 8 and the second limiting post 13. Two adjustable blades 4 are symmetrically and movably inserted on the first limiting post 9 and the second limiting post 13. The adjustable blades 4 are composed of a blade 16, a guide plate 17, and a rack 18. The guide plate 17 and the rack 18 are symmetrically fixedly installed at the inner end of the blade 16. An adjusting and fixing structure 5 is rotatably installed inside the first limiting post 9. The adjusting and fixing structure 5 is composed of a toothed ring 19, a sleeve 20, an internally threaded cylinder 21, and a bolt 6. The toothed ring 19 meshes with the rack 18. The sleeve 20 is fixedly installed on the upper end of the toothed ring 19, and the internal threaded cylinder 21 is fixedly inserted into the sleeve 20. The bolt 6 is installed inside the internal threaded cylinder 21. A transmission shaft structure 3 consisting of a transmission shaft body 7, a retaining ring 8, a first limiting post 9, and a second limiting post 13 is set on the output shaft of the servo motor 2. An adjustable blade 4 consisting of a paddle plate 16, a guide plate 17, and a rack 18 is set on the transmission shaft structure 3, as well as an adjustment and fixing structure 5 consisting of a toothed ring 19, a sleeve 20, an internal threaded cylinder 21, and a bolt 6. Rotating the sleeve 20 can drive the toothed ring 19 to rotate. By using the meshing transmission between the toothed ring 19 and the rack 18, the adjustable blade 4 is driven to move along the slot 15 and the receiving groove 10, so as to realize the flexible adjustment of the stirring length of the adjustable blade 4, adapt to the stirring needs of materials with different volumes and viscosities, so that multiple sets of agitators are not required, reducing equipment procurement and storage costs, improving the adaptability of the reactor to different pharmaceutical and chemical reaction conditions, and ensuring the uniformity of material mixing and reaction effect.

[0015] Specifically, the first limiting post 9 on the transmission shaft structure 3 has a receiving groove 10, a first shaft hole 12 at its lower end, and a through hole 11 at its upper end. The receiving groove 10 communicates with the first shaft hole 12 and the through hole 11. The first limiting post 9 is fixedly sleeved on the transmission shaft body 7 through the first shaft hole 12. The transmission shaft body 7 is fixedly mounted on the output shaft of the servo motor 2. The second limiting post 13 on the transmission shaft structure 3 has a second shaft hole 14. The second limiting post 13 passes through the second shaft hole 14. Hole 14 is fixedly sleeved on the drive shaft body 7. Two slots 15 are symmetrically opened on both sides of the second shaft hole 14 on the second limiting post 13. The blade 16 on the adjustable blade 4 is located on one side of the drive shaft structure 3. The guide plate 17 is movably inserted into the slot 15 opened on the second limiting post 13. The rack 18 is movably inserted into the receiving groove 10 opened on the first limiting post 9. The gear ring 19 on the adjusting fixing structure 5 is rotatably installed in the receiving groove 10 opened on the first limiting post 9. The sleeve 20 passes upward through the opening on the first limiting post 9. The sleeve 20 is located below the retaining ring 8, and the inner end of the bolt 6 abuts against the drive shaft body 7. When using this reactor for pharmaceutical preparation, the pharmaceutical chemical materials to be reacted are first added into the reactor shell 1 through the feed port. The speed parameters of the servo motor 2 are set according to the reaction requirements. Then, the servo motor 2 is started. The output shaft of the servo motor 2 drives the drive shaft body 7 in the drive shaft structure 3 to rotate. The drive shaft body 7 synchronously drives the retaining ring 8, the first limiting post 9, and the second limiting post 13 fixed on it to rotate. The first limiting post 9 and the second limiting post 13 drive the adjustable blade 4 to rotate. The adjustable blade 4 stirs the materials in the reactor shell 1, so that the materials are fully mixed and react. During the reaction, the temperature, pressure and other parameters in the reactor shell 1 can be monitored as needed. After the reaction is completed, the servo motor 2 is turned off, and the reaction products are discharged through the discharge port of the reactor shell 1. Finally, the inside of the reactor shell 1 and the adjustable blade 4 and other components are cleaned for the next use.

[0016] When adjusting the adjustable blade 4 according to the stirring requirements of materials with different volumes and viscosities, first ensure that the servo motor 2 is in the stopped state. Then, loosen the bolt 6 in the adjusting fixing structure 5 so that the inner end of the bolt 6 is disengaged from the transmission shaft body 7, thereby releasing the fixation of the sleeve 20. Then, use a tool to rotate the sleeve 20. The sleeve 20 drives the fixedly connected toothed ring 19 to rotate in the receiving groove 10 of the first limiting post 9. Since the toothed ring 19 meshes with the rack 18 of the adjustable blade 4, when the toothed ring 19 rotates, it drives the rack 18 to move horizontally in the receiving groove 10. The rack 18 drives the fixedly connected paddle 16 to move synchronously. At the same time, the guide plate 17 at the inner end of the paddle 16 slides synchronously in the slot 15 of the second limiting post 13 until the length of the paddle 16 extends meets the current stirring requirements of the material. At this time, stop rotating the sleeve 20, and then tighten the bolt 6 so that the inner end of the bolt 6 is pressed against the transmission shaft body 7 again, thereby fixing the sleeve 20 and the toothed ring 19. At this time, the adjustment of the stirring length of the adjustable blade 4 is completed.

[0017] Obviously, the above embodiments are merely illustrative examples for clear explanation and are not intended to limit the implementation. Those skilled in the art can make other variations or modifications based on the above description. It is neither necessary nor possible to exhaustively list all possible implementations here. However, obvious variations or modifications derived therefrom are still within the protection scope of this invention.

Claims

1. A pharmaceutical chemical preparation apparatus, comprising a reaction vessel shell (1), wherein a servo motor (2) is fixedly mounted on the reaction vessel shell (1), characterized in that: A transmission shaft structure (3) is fixedly installed inside the reactor shell (1) and on the output shaft of the servo motor (2). The transmission shaft structure (3) consists of a transmission shaft body (7), a retaining ring (8), a first limiting post (9), and a second limiting post (13). The retaining ring (8), the first limiting post (9), and the second limiting post (13) are all fixedly sleeved on the transmission shaft body (7). The second limiting post (13) is located below the retaining ring (8), and the first limiting post (9) is located between the retaining ring (8) and the second limiting post (13). Two adjustable blades (4) are symmetrically and movably inserted on the first limiting post (9) and the second limiting post (13). The adjustable blade (4) consists of a blade (16), a guide plate (17), and a rack (18). The guide plate (17) and the rack (18) are symmetrically fixedly installed at the inner end of the blade (16). An adjustment and fixing structure (5) is rotatably installed inside the first limiting post (9). The adjustment and fixing structure (5) consists of a toothed ring (19), a sleeve (20), an internal threaded cylinder (21), and a bolt (6). The toothed ring (19) meshes with the rack (18). The sleeve (20) is fixedly installed at the upper end of the toothed ring (19). The internal threaded cylinder (21) is fixedly inserted into the sleeve (20). The bolt (6) is installed inside the internal threaded cylinder (21).

2. The pharmaceutical chemical preparation apparatus according to claim 1, characterized in that: The first limiting post (9) on the transmission shaft structure (3) is provided with a receiving groove (10), the lower end of the first limiting post (9) is provided with a first shaft hole (12), and the upper end of the first limiting post (9) is provided with a through hole (11). The receiving groove (10) is connected to the first shaft hole (12) and the through hole (11). The first limiting post (9) is fixedly sleeved on the transmission shaft body (7) through the first shaft hole (12). The transmission shaft body (7) is fixedly installed on the output shaft of the servo motor (2).

3. The pharmaceutical chemical preparation apparatus according to claim 2, characterized in that: The second limiting post (13) on the transmission shaft structure (3) has a second shaft hole (14). The second limiting post (13) is fixedly sleeved on the transmission shaft body (7) through the second shaft hole (14). Two slots (15) are symmetrically opened on the second limiting post (13) and on both sides of the second shaft hole (14).

4. The pharmaceutical chemical preparation apparatus according to claim 3, characterized in that: The blade (16) on the adjustable blade (4) is located on one side of the transmission shaft structure (3), the guide plate (17) is movably inserted into the slot (15) opened on the second limiting post (13), and the rack (18) is movably inserted into the receiving groove (10) opened on the first limiting post (9).

5. The pharmaceutical chemical preparation apparatus according to claim 4, characterized in that: The toothed ring (19) on the adjusting and fixing structure (5) is rotatably installed in the receiving groove (10) opened on the first limiting post (9). The sleeve (20) passes upward through the through hole (11) opened on the first limiting post (9), and the sleeve (20) is simultaneously located below the retaining ring (8). The inner end of the bolt (6) abuts against the transmission shaft body (7).

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