A microsphere plate separation device

By designing a microsphere plate separation device, the rapid dispensing of microspheres is achieved using insert plates and through-hole structures, which solves the problem of low dispensing efficiency of lyophilized diagnostic reagents, improves dispensing efficiency and product yield, and extends the shelf life of materials.

CN224546359UActive Publication Date: 2026-07-24SHANGHAI TOFFLON SCI & TECH CO LTD
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
SHANGHAI TOFFLON SCI & TECH CO LTD
Filing Date
2025-07-14
Publication Date
2026-07-24

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Abstract

The utility model discloses a kind of microsphere flat plate separation devices, including lower plate, plug-in board, upper plate and feed assembly;The upper end of the lower plate is connected with the upper plate, the plug-in board is inserted between the lower plate and the upper plate, and is slidably connected with the lower plate and the upper plate;A plurality of third through holes are opened on the upper plate, and the third through hole upper port is connected with the feed assembly;A plurality of first through holes are opened on the lower plate;Wherein, through the horizontal movement of plug-in board, the quick subpackaging of microsphere fixed number of particles is realized.The utility model aims at overcoming the defects of the prior art to provide a kind of microsphere flat plate separation device, shorten subpackaging time, improve subpackaging efficiency.
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Description

Technical Field

[0001] This utility model relates to a microsphere plate separation device. Background Technology

[0002] Lyophilized microsphere reagents are reagents formed by processing microspheres through freeze-drying technology, and they are widely used in biological, medical and other fields.

[0003] Key features include: High stability: The freeze-drying process slows down the degradation rate of bioactive substances (such as antibodies, antigens, and enzymes) in the microspheres, extending the shelf life of the reagents and facilitating storage and transportation. It can be stored for extended periods at room temperature or lower temperatures. Convenience: Simply add an appropriate amount of solvent (such as distilled water or buffer solution) to quickly reconstitute the freeze-dried microspheres, restoring their original properties and functions. Operation is simple and quick. Good uniformity: The microspheres undergo uniform dispersion treatment before freeze-drying, maintaining good uniformity afterward. This ensures consistent reagent performance for each use, improving the accuracy and repeatability of detection or experimental results. Strong adaptability: Different microsphere materials and freeze-drying processes can be selected to prepare freeze-dried microsphere reagents with specific functions, suitable for various detection methods and experimental systems, according to different application requirements.

[0004] Existing lyophilized diagnostic reagents using conventional filling methods are prone to rapid liquid evaporation, leading to product inactivation; furthermore, there is a risk of chemical reactions occurring in the liquid reagents during the pre-freezing stage. A dispensing machine can rapidly freeze reagent droplets into granules using liquid nitrogen, which are then transferred to a lyophilizer for low-temperature vacuum drying, facilitating storage and transportation. Current manual granule dispensing methods are slow, time-consuming, inefficient, and the granules are susceptible to moisture and greatly affected by external factors. Therefore, a microsphere plate separation device is proposed to address these issues. Utility Model Content

[0005] The purpose of this invention is to overcome the existing defects and provide a microsphere plate separation device that shortens the dispensing time and improves dispensing efficiency.

[0006] To achieve the above objectives, this utility model provides the following technical solution: a microsphere plate separation device, comprising a lower plate, an insertion plate, an upper plate, and a feeding assembly;

[0007] The upper end of the lower plate is connected to the upper plate, and the insert plate is inserted between the lower plate and the upper plate and is slidably connected to the lower plate and the upper plate; the upper plate has a plurality of third through holes, and the upper end of the third through holes is connected to the feeding assembly;

[0008] Multiple first through holes are provided on the lower plate;

[0009] The system achieves rapid dispensing of a fixed number of microspheres by horizontally moving the insert plate.

[0010] Preferably, the feeding assembly includes multiple hoses, with one hose connected to the upper port of each of the third through holes.

[0011] Preferably, the insert plate is a middle plate, and the middle plate has multiple second through holes.

[0012] Preferably, the upper end face of the lower plate has an insertion groove, and the middle plate is inserted into the insertion groove.

[0013] Preferably, the hole spacing between the plurality of first through holes, the plurality of second through holes and the plurality of third through holes is the same.

[0014] Preferably, the plurality of first through holes, the plurality of second through holes, and the plurality of third through holes have the same diameter.

[0015] Preferably, the centers of the first through hole and the third through hole are not on a straight line.

[0016] Compared with the prior art, the beneficial effects of this utility model are: This microsphere plate separation device can quickly separate microspheres, effectively reducing the difficulty of automatic microsphere separation, shortening the separation time, improving product yield and separation efficiency, reducing external influencing factors, helping to extend the shelf life of materials, and shortening the production cycle. Attached Figure Description

[0017] The accompanying drawings are provided to further illustrate the present invention and form part of the specification. They are used together with the embodiments of the present invention to explain the present invention, but do not constitute a limitation thereof. In the drawings:

[0018] Figure 1 This is a side view of the microsphere plate separation device of this utility model;

[0019] Figure 2 This is a top view of the microsphere plate separation device of this utility model;

[0020] Figure 3 This is a cross-sectional view of the microsphere plate separation device of this utility model.

[0021] In the diagram: 1. Lower plate; 2. Middle plate; 3. Upper plate; 4. Flexible tube; 5. First through hole; 6. Second through hole; 7. Third through hole; 8. Insertion groove; 9. Microsphere. Detailed Implementation

[0022] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0023] Please see Figure 1-3 A microsphere plate separation device includes a lower plate 1, an insert plate, an upper plate 3, and a feeding assembly; the upper end of the lower plate 1 is connected to the upper plate 3, and the insert plate is inserted between the lower plate 1 and the upper plate 3, and is slidably connected to the lower plate 1 and the upper plate 3; the upper plate 3 has multiple third through holes 7, and the upper end of the third through holes 7 is connected to the feeding assembly; the lower plate 1 has multiple first through holes 5; wherein, the horizontal movement of the insert plate enables rapid separation of a fixed number of microspheres.

[0024] Specifically, the feeding assembly includes multiple hoses 4, with one hose 4 connected to the port of each third through hole 7.

[0025] Specifically, the insert plate is a middle plate 2, and multiple second through holes 6 are opened on the middle plate 2.

[0026] Specifically, a slot 8 is provided on the upper end face of the lower plate 1, and the middle plate 2 is inserted into the slot 8.

[0027] Specifically, the hole spacing between the multiple first through holes 5, the multiple second through holes 6, and the multiple third through holes 7 is the same.

[0028] Specifically, the diameters of the multiple first through holes 5, the multiple second through holes 6, and the multiple third through holes 7 are the same.

[0029] Specifically, the centers of the first through hole 5 and the third through hole 7 are not on a straight line.

[0030] Specifically, the microspheres 9 are arranged in a row in the hose 4, and enter the second through hole 6 on the middle plate 2 through the third through hole 7 on the upper plate 3, pushing the middle plate 2. The microspheres 9 follow the movement of the middle plate 2 and fall out through the first through hole 5 on the lower plate 1.

[0031] Specifically, the number of microballs 9 entering the middle plate 2 each time is fixed, the number of microballs 9 moving with the middle plate 2 when the middle plate 2 is pushed is also fixed, and the number of microballs 9 falling out of the hole in the lower plate 1 at the end is also fixed.

[0032] This microsphere plate separation device can quickly separate microspheres, effectively reducing the difficulty of automatic microsphere separation, shortening the separation time, improving product yield and separation efficiency, reducing external influencing factors, helping to extend the shelf life of materials, and shortening the production cycle.

[0033] Finally, it should be noted that the above are merely preferred embodiments of this utility model and are not intended to limit the utility model. Although the utility model has been described in detail with reference to the foregoing embodiments, those skilled in the art can still modify the technical solutions described in the foregoing embodiments or make equivalent substitutions for some of the technical features. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of this utility model should be included within the protection scope of this utility model.

Claims

1. A microsphere plate separation device, characterized in that, It includes a lower plate (1), an insert plate, an upper plate (3), and a feeding assembly; The upper end of the lower plate (1) is connected to the upper plate (3), and the insert plate is inserted between the lower plate (1) and the upper plate (3) and is slidably connected to the lower plate (1) and the upper plate (3); the upper plate (3) has multiple third through holes (7), and the upper end of the third through holes (7) is connected to the feeding assembly; Multiple first through holes (5) are provided on the lower plate (1); The system achieves rapid dispensing of a fixed number of microspheres by horizontally moving the insert plate.

2. The microsphere plate separation device according to claim 1, characterized in that, The feeding assembly includes multiple hoses (4), with one hose (4) connected to the upper port of each of the third through holes (7).

3. The microsphere plate separation device according to claim 1, characterized in that, The insert plate is a middle plate (2), and a plurality of second through holes (6) are opened on the middle plate (2).

4. The microsphere plate separation device according to claim 3, characterized in that, The upper end face of the lower plate (1) is provided with a plug groove (8), and the middle plate (2) is inserted into the plug groove (8).

5. The microsphere plate separation device according to claim 3, characterized in that, The spacing between the plurality of first through holes (5), the plurality of second through holes (6) and the plurality of third through holes (7) is the same.

6. The microsphere plate separation device according to claim 3, characterized in that, The first through holes (5), the second through holes (6), and the third through holes (7) have the same diameter.

7. The microsphere plate separation device according to claim 3, characterized in that, The centers of the first through hole (5) and the third through hole (7) are not on the same straight line.