A chemical solution concentration detector

Abstract

The utility model discloses a chemical solution concentration detector, including at least one sample container, at least one liquid container, concentration sensor is different with passageway switching device's interface intercommunication respectively, and sample container, liquid container are communicated with concentration sensor through passageway switching device, passageway switching device still has the quantitative ring, and passageway switching device action makes the one end of quantitative ring and sample container or liquid container intercommunication, other end and concentration sensor intercommunication or not intercommunication. The utility model discloses a chemical solution concentration detector utilizes the structure of quantitative ring and passageway switching device, has realized the effective control to the detection sample volume, utilizes liquid / sample and pushes sample from quantitative ring to concentration sensor, and sample forms continuous flow, has guaranteed the integrity of detection and has improved the accuracy of detection, and simultaneously still can utilize liquid to clean quantitative ring, effectively reduces the cross -contamination, and still significantly reduces the cleaning difficulty.

Description

Technical Field

[0001] This utility model relates to the field of biomedical testing instrument technology, and in particular to a chemical solution concentration detector. Background Technology

[0002] Existing chemical solution concentration sensors typically use high-precision quantitative pumps to transport samples and buffer solutions to a fixed detection cell, mix them, and then transport them to the sensor for detection. However, this detection structure and method have the following problems: high-precision quantitative pumps are costly, prone to aging, and have poor long-term stability; there is no sample filling feedback mechanism, leading to excessive sample consumption or insufficient quantification; the detection cell requires frequent cleaning, has a high risk of contamination, and has high maintenance costs. Utility Model Content

[0003] To address the problems existing in the prior art, this utility model discloses a chemical solution concentration detector.

[0004] A chemical solution concentration detector includes at least one liquid container, at least one sample container, a channel switching device, and a concentration sensor. The sample container, liquid container, and concentration sensor are each connected to different interfaces of the channel switching device. The sample container and liquid container are connected to the concentration sensor through the channel switching device. The concentration sensor is used to detect the concentration of the sample.

[0005] The channel switching device is also connected to a quantitative loop. The channel switching device is activated such that one end of the quantitative loop is connected to the sample container or the liquid container, and the other end of the quantitative loop is connected to or not connected to the concentration sensor.

[0006] In practical use, the process includes two steps: sample injection and detection. During sample injection, the channel switching device activates, connecting the quantitative loop to the sample container and the liquid container to the concentration sensor via the channel switching device. The sample from the sample container then enters the quantitative loop, and liquid from the liquid container continues to flow in, maintaining a stable baseline for the concentration sensor. Sample injection is complete once the quantitative loop is full of sample. During detection, the channel switching device activates, connecting the quantitative loop to the liquid / sample container and the concentration sensor. Liquid / sample continues to flow in, pushing the sample in the quantitative loop to the concentration sensor for concentration detection. After detection, liquid continues to flow in to clean the quantitative loop. Simultaneously, the concentration sensor monitors and confirms whether cleaning of the quantitative loop is complete, precisely controlling the cleaning time to further reduce single-detection time and improve detection efficiency.

[0007] Preferably, it also includes a gas-liquid detection module, which is used to detect whether there are bubbles or liquid at its location;

[0008] The other end of the quantitative loop is connected to a concentration sensor or a gas-liquid detection module; the gas-liquid detection module is connected to the sample container through the quantitative loop or a channel switching device.

[0009] Specifically, when liquid is filled into the metering loop, the gas in the metering loop will be expelled. Therefore, there will be air bubbles on the liquid surface at the end of the metering loop away from the sample container. Thus, when the sample is filled into the metering loop, the other end of the metering loop is connected to the gas-liquid detection module. When the gas-liquid detection module detects air bubbles or liquid, it indicates that the metering loop is full of sample.

[0010] Preferably, it also includes a waste liquid container, which is connected to a concentration sensor and a gas-liquid detection module.

[0011] Specifically, in order to maintain the baseline stability of the concentration sensor, a continuous flow of liquid is required when filling the sample into the quantitative loop. Therefore, a waste liquid container is needed to collect this liquid. When performing sample solubility detection, liquid is also needed to push the sample into the concentration sensor. This liquid, as well as the sample after detection, also needs to be collected by the waste liquid container. When filling the quantitative loop, excess sample may be generated. The excess sample also needs to be collected by the waste liquid container after passing through the gas-liquid detection module.

[0012] Preferably, the channel switching device is a two-position six-way rotary valve, and the two ends of the quantitative loop, the liquid container, the sample container, the concentration sensor, and the gas-liquid detection module are respectively connected to different interfaces of the multi-position multi-way rotary valve.

[0013] Specifically, when there is only one sample container and one liquid container, the multi-position multi-port rotary valve is preferably a two-position six-port rotary valve, and the number of ports of the multi-position multi-port rotary valve increases with the increase of the number of sample containers and the number of liquid containers.

[0014] Preferably, the gas-liquid detection module is a bubble sensor.

[0015] Specifically, bubble sensors can be optical or ultrasonic, with ultrasonic sensors being more effective. Bubble sensors distinguish between gas and liquid by the difference between the reflection of light and ultrasonic waves, thus achieving non-contact gas-liquid detection.

[0016] Preferably, the gas-liquid detection module is a capacitive liquid level sensor.

[0017] Preferably, the liquid contained in the liquid container can stabilize the baseline of the concentration sensor.

[0018] Specifically, the liquid may be a buffer solution, a equilibration solution, an ionized solution, etc.

[0019] Preferably, it also includes a power unit, which is used to provide power to the liquid in the liquid container to move toward the channel switching device and to provide power to the sample in the sample container to move toward the channel switching device.

[0020] Specifically, the power unit can be a power unit with switching function, which can switch according to specific needs and then transport the specified liquid to the specified destination; multiple power units can also be set up according to their specific required locations.

[0021] Preferably, the metering ring is detachably connected to the channel switching device, the metering ring has multiple sizes, and the capacity of the metering ring is 1ul-1000ul.

[0022] Specifically, based on the volume of the sample to be tested, select a quantitative loop of appropriate size and connect it to the channel switching device.

[0023] Compared with the prior art, the advantages of this utility model are:

[0024] By utilizing the structure of the quantitative loop and channel switching device, the quantitative loop is connected to the sample container during sample injection, enabling effective control of the sample volume. During detection, the quantitative loop is connected to the liquid and concentration sensor, and the liquid pushes the sample from the quantitative loop to the concentration sensor, forming a continuous sample flow. This ensures the integrity of the detection and improves the accuracy of the detection. At the same time, the liquid can also be used to clean the quantitative loop, effectively reducing cross-contamination and significantly reducing the difficulty of cleaning. Attached Figure Description

[0025] Figure 1 This is a schematic diagram of the chemical solution concentration detector disclosed in this utility model during sample injection.

[0026] Figure 2 This is a schematic diagram of the chemical solution concentration detector disclosed in this utility model during the detection process. Detailed Implementation

[0027] The present invention will be further described below with reference to the accompanying drawings and specific embodiments.

[0028] like Figure 1-2 As shown, the chemical solution concentration detector includes at least one liquid container 10, at least one sample container 20, a channel switching device 30, and a concentration sensor 40. The sample container 20, the liquid container 10, and the concentration sensor 40 are respectively connected to different interfaces of the channel switching device 30. The sample container 20 and the liquid container 10 are connected to the concentration sensor 40 through the channel switching device 30. The concentration sensor 40 is used to detect the concentration of the sample.

[0029] The channel switching device 30 is also connected to a quantitative loop 50. The channel switching device 30 operates such that one end of the quantitative loop is connected to the sample container 20 or the liquid container 10, and the other end of the quantitative loop 50 is connected to or not connected to the concentration sensor 40.

[0030] In practical use, the process includes two steps: sample injection and detection. During sample injection, the channel switching device 30 activates, connecting the quantitative loop 50 to the sample container 20, and the liquid container 10 is connected to the concentration sensor 40 via the channel switching device 30 (e.g., ...). Figure 1 (As shown), then the sample in sample container 20 is introduced into quantitative loop 50, and liquid in liquid container 10 is continuously introduced to maintain baseline stability of concentration sensor 40. The injection is completed once quantitative loop 50 is full of sample. During detection, channel switching device 30 is activated, connecting quantitative loop 50 with liquid container 10 / sample container 20 and concentration sensor 40 (as shown). Figure 2 As shown, liquid is continuously introduced to push the sample in the quantitative loop 50 to the concentration sensor 40 to complete the concentration detection. After the detection is completed, liquid is continued to be introduced to clean the quantitative loop 50. At the same time, the concentration sensor 40 is used to monitor and confirm whether the cleaning of the quantitative loop 50 is completed, so as to accurately control the cleaning time, further reduce the single detection time, and improve the detection efficiency.

[0031] It also includes a gas-liquid detection module 60, which is used to detect whether there are bubbles or liquid at its location;

[0032] The other end of the quantitative loop 50 is connected to the concentration sensor 40 or the gas-liquid detection module 60; the gas-liquid detection module 60 is connected to the sample container 20 through the quantitative loop 50 or the channel switching device 30.

[0033] When liquid is filled into the quantitative loop 50, the gas in the quantitative loop 50 will be expelled. Therefore, there will be air bubbles on the liquid surface at the end of the quantitative loop 50 away from the sample container 20. Thus, when the sample is filled into the quantitative loop 50, the other end of the quantitative loop 50 is connected to the gas-liquid detection module 60. When the gas-liquid detection module 60 detects air bubbles or liquid, it indicates that the quantitative loop 50 is filled with sample.

[0034] It also includes a waste liquid container 70, which is connected to a concentration sensor 40 and a gas-liquid detection module 60.

[0035] To maintain baseline stability of the concentration sensor 40, a continuous flow of liquid is required when filling the sample into the quantitative loop 50. Therefore, a waste liquid container 70 is needed to collect this liquid. When performing sample solubility detection, liquid is also needed to push the sample into the concentration sensor 40. This liquid, as well as the sample after detection, also needs to be collected by the waste liquid container 70. When the sample is filled into the quantitative loop 50, excess sample may be generated. The excess sample also needs to be collected by the waste liquid container 70 after passing through the gas-liquid detection module 60.

[0036] The rotary valve is a multi-position multi-way rotary valve. The two ends of the metering ring 50, the liquid container 10, the sample container 20, the concentration sensor 40, and the gas-liquid detection module 60 are respectively connected to different interfaces of the multi-position multi-way rotary valve.

[0037] When there is only one sample container 20 and one liquid container 10, the multi-position multi-port rotary valve is preferably a two-position six-port rotary valve. The number of ports of the multi-position multi-port rotary valve increases with the increase of the number of sample containers 20 and the number of liquid containers 10.

[0038] The gas-liquid detection module 60 is a bubble sensor.

[0039] The bubble sensor 60 can be optical or ultrasonic, with the ultrasonic type being more effective. The bubble sensor 60 distinguishes between gas and liquid by the difference between the reflection of light and ultrasonic reflection of gas and liquid, thus achieving non-contact gas and liquid detection.

[0040] The gas-liquid detection module 60 is a capacitive liquid level sensor.

[0041] The liquid contained in the liquid container 10 can stabilize the baseline of the concentration sensor 40.

[0042] The liquid can be a buffer solution, a equilibration solution, or an ionized solution.

[0043] It also includes a power unit 80, which provides power to the liquid in the liquid container 10 to move toward the channel switching device 30 and to the sample in the sample container 20 to move toward the channel switching device 30.

[0044] The power unit 80 can be a power unit 80 with a switching function, which can switch according to specific needs and then transport the specified liquid to the specified destination; multiple power units 80 can also be set up according to their specific required locations.

[0045] It also includes a first power unit 81, which is located between the liquid container 10 and the channel switching device 30 and is used to provide power for the buffer solution in the liquid container 10 to move toward the channel switching device 30.

[0046] Activating the first power unit 81 causes the buffer solution in the liquid container 10 to flow toward the channel switching device 30; turning off the first power unit 81 stops the flow of the buffer solution.

[0047] It also includes a second power unit 82, which is located between the sample container 20 and the channel switching device 30 and is used to provide power for the sample in the sample container 20 to move toward the channel switching device 30.

[0048] Activating the second power unit 82 causes the sample in the sample container 20 to flow toward the channel switching device 30; turning off the second power unit 82 stops the sample flow.

[0049] The metering loop 50 is detachably connected to the channel switching device 30. The metering loop 50 is available in multiple sizes and has a capacity of 1ul-1000ul.

[0050] Based on the volume of the sample to be tested, select a suitable quantitative loop 50 and connect it to the channel switching device 30.

Claims

1. A chemical solution concentration detector, comprising at least one liquid container, at least one sample container, a channel switching device, and a concentration sensor, characterized in that, The sample container, liquid container, and concentration sensor are each connected to different interfaces of the channel switching device. The sample container and liquid container are connected to the concentration sensor through the channel switching device. The concentration sensor is used to detect the concentration of the sample. The channel switching device is also connected to a quantitative loop. The channel switching device is activated such that one end of the quantitative loop is connected to the sample container or the liquid container, and the other end of the quantitative loop is connected to or not connected to the concentration sensor.

2. The chemical solution concentration detector according to claim 1, characterized in that, It also includes a gas-liquid detection module, which is used to detect whether there are bubbles or liquid at its location; The other end of the quantitative loop is connected to a concentration sensor or a gas-liquid detection module; the gas-liquid detection module is connected to the sample container through the quantitative loop or a channel switching device.

3. The chemical solution concentration detector according to claim 2, characterized in that, It also includes a waste liquid container, which is connected to a concentration sensor and a gas-liquid detection module.

4. The chemical solution concentration detector according to claim 2, characterized in that, The channel switching device is a multi-position multi-way rotary valve. The two ends of the quantitative loop, the liquid container, the sample container, the concentration sensor, and the gas-liquid detection module are respectively connected to different interfaces of the multi-position multi-way rotary valve.

5. The chemical solution concentration detector according to claim 2, characterized in that, The gas-liquid detection module is a bubble sensor.

6. The chemical solution concentration detector according to claim 2, characterized in that, The gas-liquid detection module is a capacitive liquid level sensor.

7. The chemical solution concentration detector according to claim 1, characterized in that, The liquid contained in the liquid container can stabilize the baseline of the concentration sensor.

8. The chemical solution concentration detector according to claim 1, characterized in that, It also includes a power unit, which provides power to move the liquid in the liquid container toward the channel switching device and to move the sample in the sample container toward the channel switching device.

9. The chemical solution concentration detector according to claim 1, characterized in that, The quantitative ring is detachably connected to the channel switching device, and the quantitative ring is available in multiple sizes.

10. The chemical solution concentration detector according to claim 1, characterized in that, The capacity of the metering loop is 1ul-1000ul.

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