A thin layer chromatography spotting device

Abstract

The utility model provides a kind of thin layer chromatogram sample application device, including base, the base is provided with sample application platform, the sample application platform is provided with sample application seat, the one side of the sample application platform is provided with support, the support is provided with sample application head;The base is provided with intermittent drive assembly, the intermittent drive assembly is matched with the sample application platform;The inside of base is provided with support frame, the rotating motor passes through the support frame and is connected with the drive shaft, the drive shaft is connected with the drive gear, one end of the transmission shaft is connected with the support frame, and the other end passes through the transmission gear and is connected with the driving element, the transmission gear is engaged with the drive gear.The thin layer chromatogram sample application device provided by the utility model is provided with intermittent drive assembly, the intermittent rotation of sample application platform is driven by gear engagement driving element, continuous sample application can be realized, and sample application efficiency is improved.

Description

Technical Field

[0001] This utility model belongs to the field of chemical detection, and in particular relates to a thin-layer chromatography spotting device. Background Technology

[0002] Thin-layer chromatography, also known as thin-layer chromatography, is a type of solid-liquid adsorption chromatography. It utilizes the inconsistent adsorption capacity of different components for the same adsorbent, causing continuous and repeated adsorption and desorption as the mobile phase flows through the stationary phase, thus separating the components. This method is simple to operate, provides rapid identification results, and is widely used in the analysis and identification of organic compounds, the tracking and identification of organic synthesis reactions, the inspection of impurities in pharmaceutical analysis, the determination of effective components or parts of traditional Chinese medicine, and the exploration and determination of column chromatographic elution conditions in the separation and purification of traditional Chinese medicine.

[0003] Spotting is crucial for achieving accurate quantification and rapid separation in thin-layer chromatography (TLC). Currently, manual spotting typically involves drawing a parallel line with a pencil 0.8-1.5 cm from the bottom edge of the TLC plate, then repeatedly spotting the sample along this line using a glass capillary or microsyringe. However, inaccurate pressure application can easily scratch or puncture the coating on the TLC plate, making it difficult to control the size and spacing of the spotting spots, thus affecting spotting quality. Furthermore, manual spotting is slow, its accuracy is easily affected by human factors, and its efficiency is low. Summary of the Invention

[0004] In view of this, the present invention aims to overcome the defects in the prior art and propose a thin-layer chromatography spotting device.

[0005] To achieve the above objectives, the technical solution of this utility model is implemented as follows:

[0006] A thin-layer chromatography spotting device includes a base, a spotting platform on the base, a plurality of spotting seats on the spotting platform, a support on one side of the spotting platform, and a spotting head on the support.

[0007] The base is equipped with an intermittent drive component, which cooperates with the spotting stage.

[0008] Furthermore, the intermittent drive assembly includes a rotary motor, a drive gear, a transmission gear, a drive shaft, a transmission shaft, and a drive component. A support frame is internally provided in the base. The rotary motor passes through the support frame and is connected to the drive shaft. The drive shaft is connected to the drive gear. One end of the transmission shaft is connected to the support frame, and the other end passes through the transmission gear and is connected to the drive component. The transmission gear meshes with the drive gear, and the drive component cooperates with the sampling stage. The rotary motor drives the drive shaft to rotate, which synchronously drives the drive gear to rotate. The drive gear, through meshing, drives the transmission gear to rotate, which in turn drives the drive component to rotate. The drive component, through its cooperation with the sampling stage, drives the rotation of the sampling stage. The center of the drive gear coincides with the center of the sampling stage. The drive shaft can be connected to the support frame via bearings.

[0009] Furthermore, a plurality of drive grooves are provided below the sampling stage. One end of the drive groove is close to the center of the sampling stage, and the other end is located at the edge of the sampling stage. A guide groove is provided between adjacent drive grooves, and the guide groove is located at the edge of the sampling stage.

[0010] Furthermore, one end of the driving component is provided with a driving block, and the other end is provided with a guide block. The driving block cooperates with the driving groove, and the guide block cooperates with the guide groove. The transmission gear at the middle position of the sampling stage drives the rotation of the driving component, and the driving component drives the sampling seat to rotate through the cooperation of the driving block and the driving groove. When the driving component rotates, the driving block reciprocates in the driving groove, passes through the center of the sampling stage, and rotates to the next driving groove, continuing to reciprocate. While the driving block moves, the guide block moves in the guide groove. When the driving block moves at the center of the sampling stage, it cannot drive the rotation of the sampling stage. At this time, the sampling stage is in a stationary state, and the corresponding sampling seat is located below the sampling head, allowing sampling. After sampling is completed, the driving block enters the next driving groove, driving the sampling stage to rotate. After the driving block reciprocates, the next sampling seat is located below the sampling head, allowing sampling. This cycle repeats to achieve continuous sampling.

[0011] Furthermore, the distance between the drive shaft and the edge of the guide block is less than the distance between the drive shaft and the edge of the drive block. This prevents the guide block from colliding with the drive groove.

[0012] Furthermore, the edge of the guide block has an arc-shaped structure, which facilitates its fit with the guide groove.

[0013] Furthermore, the number of driving slots is 4, and the included angle between adjacent driving slots is 90 degrees; the number of sample holders is the same as the number of driving slots, and the position of the sample holders corresponds to the position of the sample head.

[0014] Compared with the prior art, this utility model has the following advantages:

[0015] The thin-layer chromatography spotting device of this invention is equipped with an intermittent drive component, which drives the spotting stage to rotate intermittently through gear meshing, thereby achieving continuous spotting, saving manpower and improving spotting efficiency. Attached Figure Description

[0016] The accompanying drawings, which form part of this utility model, are used to provide a further understanding of the utility model. The illustrative embodiments of the utility model and their descriptions are used to explain the utility model and do not constitute an undue limitation of the utility model. In the drawings:

[0017] Figure 1 This is a schematic diagram of the thin-layer chromatography spotting device described in an embodiment of the present invention;

[0018] Figure 2 This is a schematic diagram of the intermittent drive component described in an embodiment of the present utility model;

[0019] Figure 3 This is a schematic diagram of the drive gear described in an embodiment of the present utility model;

[0020] Figure 4 This is a schematic diagram of the driving component described in an embodiment of the present utility model.

[0021] Explanation of reference numerals in the attached figures:

[0022] 1. Dispensing head; 2. Base; 3. Dispensing stage; 4. Rotary motor; 5. Drive gear; 6. Transmission gear; 7. Drive shaft; 8. Transmission shaft; 9. Drive component; 10. Support frame; 31. Guide groove; 32. Drive groove; 33. Dispensing seat; 91. Drive block; 92. Guide block. Detailed Implementation

[0023] It should be noted that, unless otherwise specified, the embodiments and features described in these embodiments can be combined with each other.

[0024] In the description of this utility model, it should be understood that the terms "center," "longitudinal," "lateral," "upper," "lower," "front," "rear," "left," "right," "vertical," "horizontal," "top," "bottom," "inner," and "outer," etc., indicating orientation or positional relationships based on the orientation or positional relationships shown in the accompanying drawings, are only for the convenience of describing this utility model and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of this utility model. Furthermore, the terms "first," "second," etc., are used for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of indicated technical features. Thus, features defined with "first," "second," etc., may explicitly or implicitly include one or more of that feature. In the description of this utility model, unless otherwise stated, "a plurality of" means two or more.

[0025] In the description of this utility model, it should be noted that, unless otherwise explicitly specified and limited, the terms "installation," "connection," and "joining" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; and they can refer to the internal connection of two components. Those skilled in the art can understand the specific meaning of the above terms in this utility model based on the specific circumstances.

[0026] The present invention will now be described in detail with reference to the accompanying drawings and embodiments.

[0027] like Figure 1-4 As shown, a thin-layer chromatography spotting device includes a base 2, a spotting stage 3 on the base 2, four spotting seats 33 on the spotting stage, a support on one side of the spotting stage, and a spotting head 1 on the support; an intermittent drive assembly is provided inside the base 2, and the intermittent drive assembly cooperates with the spotting stage 3.

[0028] The intermittent drive assembly includes a rotary motor 4, a drive gear 5, a transmission gear 6, a drive shaft 7, a transmission shaft 8, and a drive component 9. A support frame 10 is provided inside the base 2. The rotary motor 4 passes through the support frame 10 and is connected to the drive shaft 7. The drive shaft 7 is connected to the drive gear 5. One end of the transmission shaft 8 is connected to the support frame 10, and the other end passes through the transmission gear 6 and is connected to the drive component 9. The transmission gear 6 meshes with the drive gear 5. The drive component 9 cooperates with the sampling stage 3. The rotary motor 4 drives the drive shaft 7 to rotate, which in turn drives the drive gear 5 to rotate. The drive gear 5, through meshing, drives the transmission gear 6 to rotate, which in turn drives the drive component 9 to rotate. The drive component 9, through its cooperation with the sampling stage 3, drives the rotation of the sampling stage 3. The center of the drive gear 5 coincides with the center of the sampling stage 3. The drive shaft 7 is connected to the support frame 10 via bearings.

[0029] Four drive slots 32 are provided below the sampling stage 3. One end of each drive slot 32 is close to the center of the sampling stage 3, and the other end is located at the edge of the sampling stage 3. A guide slot 31 is provided between adjacent drive slots 32, and the guide slot 31 is located at the edge of the sampling stage 3.

[0030] The driving component 9 has a driving block 91 at one end and a guide block 92 at the other end. The driving block 91 engages with the driving groove 32, and the guide block 92 engages with the guide groove 31. The transmission gear 6 at the middle position of the sampling stage 3 drives the rotation of the driving component 9. The driving component 9 drives the sampling seat 33 to rotate through the engagement of the driving block 91 and the driving groove 32. When the driving component 9 rotates, the driving block 91 reciprocates within the driving groove 32, passes through the center of the sampling stage 3, and rotates to the next driving groove 32, continuing its reciprocating movement. Simultaneously, the guide block 92 moves within the guide groove 31. When the drive block 91 moves at the center of the sampling stage 3, it cannot drive the sampling stage 3 to rotate. At this time, the sampling stage 3 is stationary, and the corresponding sampling seat 33 is located below the sampling head 1, allowing sampling to be performed. After sampling is completed, the drive block 91 enters the next drive groove 32, driving the sampling stage 3 to rotate. After the drive block 91 completes its reciprocating movement, the next sampling seat 33 is located below the sampling head 1, and sampling is performed. This cycle repeats to achieve continuous sampling. The distance between the drive shaft 8 and the edge of the guide block 92 is less than the distance between the drive shaft 8 and the edge of the drive block 91. This prevents the guide block 92 from colliding with the drive groove 32. The edge of the guide block 92 has an arc-shaped structure to facilitate its cooperation with the guide groove 31.

[0031] The number of drive slots 32 is 4, and the included angle between adjacent drive slots 32 is 90 degrees; the number of sample holders 33 is the same as the number of drive slots 32, and the position of the sample holders 33 corresponds to the position of the sample head 1.

[0032] Implementation process:

[0033] The rotary motor 4 drives the drive shaft 7 to rotate, which in turn drives the drive gear 5 to rotate. The drive gear 5 meshes with the transmission gear 6, which in turn drives the drive component 9 to rotate. As the drive component 9 rotates, the drive block 91 reciprocates in the drive groove 32, passes through the center of the sampling stage 3, and rotates to the next drive groove 32, continuing its reciprocating motion. Simultaneously, the guide block 92 moves within the guide groove 31. When the drive block 91 moves to the center of the sampling stage 3, it disengages from the previous drive groove 32, at which point the sampling stage 3 is stationary, and the corresponding sampling seat 33 is located below the sampling head 1, ready for sampling. After sampling is completed, the drive block 91 enters the next drive groove 32, driving the sampling stage 3 to rotate. After the drive block 91 completes its reciprocating motion, the next sampling seat 33 is located below the sampling head 1, ready for sampling. This cycle repeats, achieving continuous sampling.

[0034] The above description is only a preferred embodiment of the present utility model and is not intended to limit the present utility model. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present utility model should be included within the protection scope of the present utility model.

Claims

1. A thin layer chromatography spotting device characterized by: Includes a base (2), on which a sampling platform (3) is provided, and on which a plurality of sampling seats (33) are provided, and on one side of the sampling platform a support is provided, and on the support a sampling head (1) is provided. The base (2) is provided with an intermittent drive component, which cooperates with the spotting stage (3).

2. The thin layer chromatography spotting device of claim 1, wherein: The intermittent drive assembly includes a rotary motor (4), a drive gear (5), a transmission gear (6), a drive shaft (7), a transmission shaft (8), and a drive component (9). The base (2) has a support frame (10) inside. The rotary motor (4) passes through the support frame (10) and is connected to the drive shaft (7). The drive shaft (7) is connected to the drive gear (5). One end of the transmission shaft (8) is connected to the support frame (10), and the other end passes through the transmission gear (6) and is connected to the drive component (9). The transmission gear (6) meshes with the drive gear (5), and the drive component (9) cooperates with the sampling stage (3).

3. The thin layer chromatography spotting device of claim 2, wherein: The sample dispensing stage (3) is provided with several drive grooves (32) below it. One end of the drive groove (32) is close to the center of the sample dispensing stage (3), and the other end is located at the edge of the sample dispensing stage (3). A guide groove (31) is provided between adjacent drive grooves (32), and the guide groove (31) is located at the edge of the sample dispensing stage (3).

4. The thin-layer chromatography spotting apparatus according to claim 3, characterized in that: One end of the driving component (9) is provided with a driving block (91) and the other end is provided with a guide block (92). The driving block (91) cooperates with the driving groove (32) and the guide block (92) cooperates with the guide groove (31).

5. The thin-layer chromatography spotting apparatus according to claim 4, characterized in that: The distance between the drive shaft (8) and the edge of the guide block (92) is less than the distance between the drive shaft (8) and the edge of the drive block (91).

6. The thin-layer chromatography spotting apparatus according to claim 5, characterized in that: The edge of the guide block (92) is an arc-shaped structure.

7. The thin-layer chromatography spotting apparatus according to claim 6, characterized in that: The number of drive slots (32) is 4, and the included angle between adjacent drive slots (32) is 90 degrees; the number of sample holders (33) is the same as the number of drive slots (32), and the position of the sample holders (33) corresponds to the position of the sample head (1).

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